Clinical Application of C-Reactive Protein for Cardiovascular Disease Detection and Prevention

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

Ridker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003233421202 · Cited by 5,850

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

Ridker, P. M., Cushman, M., Stampfer, M. J., Tracy, R. P., & Hennekens, C. H. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704033361401 · Cited by 5,504

C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus

Pradhan, A. D. (2001) · JAMA · doi:10.1001/jama.286.3.327 · Cited by 4,433

Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events

Ridker, P. M., Rifai, N., Rose, L., Buring, J. E., & Cook, N. R. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021993 · Cited by 3,604

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

Liuzzo, G., Biasucci, L. M., Gallimore, J. R., Grillo, R. L., Rebuzzi, A. G., Pepys, M. B., & Maseri, A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408183310701 · Cited by 2,354

C-Reactive Protein, the Metabolic Syndrome, and Risk of Incident Cardiovascular Events: An 8-Year Follow-Up of 14 719 Initially Healthy American Women

Ridker, P. M., Buring, J. E., Cook, N. R., & Rifai, N. (2003) · Circulation · doi:10.1161/01.cir.0000055014.62083.05 · Cited by 2,292

C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men

Köenig, W., Sund, M., Fröhlich, M., Fischer, H.-G., Löwel, H., Döring, A., Hutchinson, W. L., & Pepys, M. B. (1999) · Circulation · doi:10.1161/01.cir.99.2.237 · Cited by 1,952

Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses

Danesh, J. (2000) · BMJ · doi:10.1136/bmj.321.7255.199 · Cited by 1,692

Effect of Statin Therapy on C-Reactive Protein Levels

Albert, M. A., Danielson, E., Rifai, N., Ridker, P. M., & for the PRINCE Investigators (2001) · JAMA · doi:10.1001/jama.286.1.64 · Cited by 1,644

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

Ridker, P. M., Rifai, N., Clearfield, M., Downs, J. R., Weis, S. E., Miles, J. S., & Gotto, A. M. (2001) · New England Journal of Medicine · doi:10.1056/nejm200106283442601 · Cited by 1,557

Serum C-reactive protein concentrations are inversely associated with dietary flavonoid intake in U.S. adults

Chun, O. K., Chung, S.-J., Claycombe, K. J., & Song, W. O. (2008) · The Journal of Nutrition · doi:10.1093/jn/138.4.753 · Cited by 263

Clinical utility of inflammatory markers and advanced lipoprotein testing: Advice from an expert panel of lipid specialists

Davidson, M. H., Ballantyne, C. M., Jacobson, T. A., Bittner, V. A., Braun, L. T., Brown, A. S., Brown, W. V., Cromwell, W. C., Goldberg, R. B., McKenney, J. M., et al. (2011) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2011.07.005 · Cited by 262

Independent Association Between Plasma Leptin and C-Reactive Protein in Healthy Humans

Shamsuzzaman, A., Winnicki, M., Wolk, R. A., Svatikova, A., Phillips, B. G., Davison, D. E., Berger, P. B., & Somers, V. K. (2004) · Circulation · doi:10.1161/01.cir.0000127960.28627.75 · Cited by 262

The natural history of chronic obstructive pulmonary disease

Mannino, D. M., Watt, G. C. M., Hole, D. J., Gillis, C. R., Hart, C., McConnachie, A., Smith, G. D., Upton, M. N., Hawthorne, V. M., Sin, D. D., et al. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00024605 · Cited by 294

Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface

Miller, A. H. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2008.08.006 · Cited by 261

High-sensitivity C-reactive protein and cardiovascular risk: rationale for screening and primary prevention

Ridker, P. M. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(03)00774-4 · Cited by 261

State of the Science: Chronic Periodontitis and Systemic Health

Otomo‐Corgel, J., Pucher, J. J., Rethman, M. P., & Reynolds, M. A. (2012) · Journal of Evidence Based Dental Practice · doi:10.1016/s1532-3382(12)70006-4 · Cited by 258

S100B in neuropathologic states: The CRP of the brain?

Sen, J., & Belli, A. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21211 · Cited by 258

Results From the Periodontitis and Vascular Events (PAVE) Study: A Pilot Multicentered, Randomized, Controlled Trial to Study Effects of Periodontal Therapy in a Secondary Prevention Model of Cardiovascular Disease

Offenbacher, S., Beck, J. D., MOSS, K. L., Mendoza, L., Paquette, D. W., Barrow, D. A., Couper, D. J., Stewart, D., Falkner, K. L., Graham, S., et al. (2009) · Journal of Periodontology · doi:10.1902/jop.2009.080007 · Cited by 262

Association Between Elevated Liver Enzymes and C-Reactive Protein

Kerner, A., Avizohar, O., Sella, R., Bartha, P., Zinder, O., Markiewicz, W., Levy, Y., Brook, G. J., & Aronson, D. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000148324.63685.6a · Cited by 257

Antioxidant Vitamins C and E Improve Endothelial Function in Children With Hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial

Engler, M. M., Engler, M. B., Malloy, M. J., Chiu, E. Y., Schloetter, M. C., Paul, S. M., Stuehlinger, M., Lin, K. Y., Cooke, J. P., Morrow, J. D., et al. (2003) · Circulation · doi:10.1161/01.cir.0000086345.09861.a0 · Cited by 253

Soluble Urokinase Plasminogen Activator Receptor (suPAR) as a Biomarker of Systemic Chronic Inflammation

Rasmussen, L. J. H., Petersen, J. E. V., & Eugen‐Olsen, J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.780641 · Cited by 261

Coronary artery plaque characteristics and treatment with biologic therapy in severe psoriasis: results from a prospective observational study

Elnabawi, Y. A., Dey, A. K., Goyal, A., Groenendyk, J., Chung, J. H. N., Belur, A. D., Rodante, J. A., Harrington, C. L., Teague, H., Baumer, Y., et al. (2019) · Cardiovascular Research · doi:10.1093/cvr/cvz009 · Cited by 248

Statins Reduce Interleukin-6–Induced C-Reactive Protein in Human Hepatocytes: New Evidence for Direct Antiinflammatory Effects of Statins

Arnaud, C., Burger, F., Steffens, S., Veillard, N. R., Nguyen, T. H., Trono, D., & Mach, F. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000163840.63685.0c · Cited by 247

Serum Levels of Interleukin‐6 and C‐Reactive Protein Correlate With Body Mass Index Across the Broad Range of Obesity

Khaodhiar, L., Ling, P., Blackburn, G. L., & Bistrian, B. R. (2004) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607104028006410 · Cited by 243

The Metabolic Syndrome and Inflammation

Sutherland, J. P., McKinley, B., & Eckel, R. H. (2004) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2004.2.82 · Cited by 243

Physical Activity and High-Sensitivity C-Reactive Protein

Plaisance, E. P., & Grandjean, P. W. (2006) · Sports Medicine · doi:10.2165/00007256-200636050-00006 · Cited by 246

Elevated serum levels of alanine aminotransferase and gamma glutamyltransferase are markers of inflammation and oxidative stress independent of the metabolic syndrome

Yamada, J., Tomiyama, H., Yambe, M., Koji, Y., Motobe, K., Shiina, K., Yamamoto, Y., & Yamashina, A. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.11.036 · Cited by 242

Elevated Interleukin-18 Levels Are Associated With the Metabolic Syndrome Independent of Obesity and Insulin Resistance

Hung, J., McQuillan, B., Chapman, C., Thompson, P. L., & Beilby, J. P. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000163843.70369.12 · Cited by 240

Diffuse and Active Inflammation Occurs in Both Vulnerable and Stable Plaques of the Entire Coronary Tree

Mauriello, A., Sangiorgi, G., Fratoni, S., Palmieri, G., Bonanno, E., Anemona, L., Schwartz, R. S., & Spagnoli, L. G. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.01.054 · Cited by 238

Multi-Biomarker Risk Stratification of N-Terminal Pro-B-Type Natriuretic Peptide, High-Sensitivity C-Reactive Protein, and Cardiac Troponin T and I in End-Stage Renal Disease for All-Cause Death

Apple, F. S., Murakami, M. M., Pearce, L. A., & Herzog, C. A. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2004.035741 · Cited by 238

Multiple Markers of Inflammation and Weight Status: Cross-sectional Analyses Throughout Childhood

Skinner, A. C., Steiner, M. J., Henderson, F. W., & Perrin, E. M. (2010) · PEDIATRICS · doi:10.1542/peds.2009-2182 · Cited by 237

The Roles of Hypoxia Signaling in the Pathogenesis of Cardiovascular Diseases

Abe, H., Semba, H., & Takeda, N. (2017) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.rv17009 · Cited by 244

Circulating Pregnancy-Associated Plasma Protein A Predicts Outcome in Patients With Acute Coronary Syndrome but No Troponin I Elevation

Lund, J., Qin, Q., Ilva, T., Pettersson, K. S. I., Voipio‐Pulkki, L., Porela, P., & Pulkki, K. J. (2003) · Circulation · doi:10.1161/01.cir.0000096054.18485.07 · Cited by 233

Local Production of Lipoprotein-Associated Phospholipase A 2 and Lysophosphatidylcholine in the Coronary Circulation

Lavi, S., McConnell, J. P., Rihal, C. S., Prasad, A., Mathew, V., Lerman, L. O., & Lerman, A. (2007) · Circulation · doi:10.1161/circulationaha.106.671420 · Cited by 229

Circulating endothelial progenitor cells in patients with unstable angina: association with systemic inflammation

George, J. (2004) · European Heart Journal · doi:10.1016/j.ehj.2004.03.026 · Cited by 227

Influence of anti-tumour necrosis factor therapy on cardiovascular risk factors in patients with active rheumatoid arthritis

Popa, C. D., Netea, M. G., Radstake, T. R. D. J., der Meer, J. W. M. V., Stalenhoef, A. F. H., van Riel, P. L. C. M., & Barerra, P. (2004) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2004.023119 · Cited by 224

Fetuin-Mineral Complex Reflects Extraosseous Calcification Stress in CKD

Hamano, T., Matsui, I., Mikami, S., Tomida, K., Fujii, N., Imai, E., Rakugi, H., & Isaka, Y. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009090944 · Cited by 223

Carbohydrate Intake, Glycemic Index, Glycemic Load, and Dietary Fiber in Relation to Risk of Stroke in Women

Oh, K. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi026 · Cited by 220

Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28 838 middle-aged men and women

Lee, D.-H. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl086 · Cited by 219

Association of Common CRP Gene Variants with CRP Levels and Cardiovascular Events

Miller, D. T., Zee, R. Y. L., Suk Danik, J., Kozlowski, P., Chasman, D. I., Lazarus, R., Cook, N. R., Ridker, P. M., & Kwiatkowski, D. J. (2005) · Annals of Human Genetics · doi:10.1111/j.1529-8817.2005.00210.x · Cited by 220

Sedentary Time and Markers of Chronic Low-Grade Inflammation in a High Risk Population

Henson, J. J., Yates, T. E., Edwardson, C. L., Khunti, K. K., Talbot, D. C. S., Gray, L. J., Leigh, T. M., Carter, P., & Davies, M. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078350 · Cited by 219

Association between serum gamma-glutamyltransferase and C-reactive protein

Lee, D., & Jacobs, D. R. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.08.027 · Cited by 216

The novel role of C-reactive protein in cardiovascular disease: Risk marker or pathogen

Wilson, A., Ryan, M. C., & Boyle, A. (2005) · International Journal of Cardiology · doi:10.1016/j.ijcard.2005.01.068 · Cited by 217

Bad Marriage, Broken Heart? Age and Gender Differences in the Link between Marital Quality and Cardiovascular Risks among Older Adults

Liu, H., & Waite, L. J. (2014) · Journal of Health and Social Behavior · doi:10.1177/0022146514556893 · Cited by 218

C-Reactive Protein Is a Marker for Human Immunodeficiency Virus Disease Progression

Lau, B. M. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.1.64 · Cited by 212

The Effect of Darapladib on Plasma Lipoprotein-Associated Phospholipase A2 Activity and Cardiovascular Biomarkers in Patients With Stable Coronary Heart Disease or Coronary Heart Disease Risk Equivalent

Mohler, E. R., Ballantyne, C. M., Davidson, M. H., Hanefeld, M., Ruilope, L. M., Johnson, J. L., & Zalewski, A. A. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.11.079 · Cited by 210

Multiple Plaque Rupture and C-Reactive Protein in Acute Myocardial Infarction

Tanaka, A., Shimada, K., Sano, T., Namba, M., Sakamoto, T., Nishida, Y., Kawarabayashi, T., Fukuda, D., & Yoshikawa, J. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.01.053 · Cited by 211

Circulating inflammatory markers and risks of cardiovascular and non‐cardiovascular disease

Lowe, G. D. O. (2005) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2005.01416.x · Cited by 211

Developmental psychoneuroendocrine and psychoneuroimmune pathways from childhood adversity to disease

Kuhlman, K. R., Chiang, J. J., Horn, S., & Bower, J. E. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.05.020 · Cited by 208

Vascular Calcification: Pathophysiology and Risk Factors

Chen, N. X., & Moe, S. M. (2012) · Current Hypertension Reports · doi:10.1007/s11906-012-0265-8 · Cited by 207

Sensitive and Quantitative Detection of C-Reaction Protein Based on Immunofluorescent Nanospheres Coupled with Lateral Flow Test Strip

Hu, J., Zhang, Z., Wen, C., Tang, M., Wu, L., Liu, C., Zhu, L. Q., & Pang, D. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b01427 · Cited by 205

Aspirin-Triggered Lipoxin and Resolvin E1 Modulate Vascular Smooth Muscle Phenotype and Correlate with Peripheral Atherosclerosis

Ho, K. J., Spite, M., Owens, C. D., Lancero, H., Kroemer, A. H. K., Pande, R., Creager, M. A., Serhan, C. N., & Conte, M. S. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.091082 · Cited by 204

Oxidized low density lipoprotein and innate immune receptors

Miller, Y. I., Chang, M.-K., Binder, C. J., Shaw, P. X., & Witztum, J. L. (2003) · Current Opinion in Lipidology · doi:10.1097/00041433-200310000-00004 · Cited by 200

Myeloid-related protein 8/14 complex is released by monocytes and granulocytes at the site of coronary occlusion: a novel, early, and sensitive marker of acute coronary syndromes

Altwegg, L., Neidhart, M., Hersberger, M., Muller, S., Eberli, F. R., Corti, R., Roffi, M., Sütsch, G., Gay, S., von Eckardstein, A., et al. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehm078 · Cited by 199

Population Distributions of C-reactive Protein in Apparently Healthy Men and Women in the United States: Implication for Clinical Interpretation

Rifai, N., & Ridker, P. M. (2003) · Clinical Chemistry · doi:10.1373/49.4.666 · Cited by 201

Testosterone replacement therapy and cardiovascular risk

Gagliano‐Jucá, T., & Basaria, S. S. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0211-4 · Cited by 200

An Update on the Role of Markers of Inflammation in Atherosclerosis

Corrado, E., Rizzo, M., Coppola, G., Fattouch, K., Novo, G., Marturana, I., Ferrara, F., & Novo, S. (2010) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.2600 · Cited by 195

The Relationship Between Plasma Osteoprotegerin Levels and Coronary Artery Calcification in Uncomplicated Type 2 Diabetic Subjects

Anand, D. V., Lahiri, A., Lim, E., Hopkins, D., & Corder, R. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.12.054 · Cited by 191

Examining the role of neuroinflammation in major depression

Furtado, M., & Katzman, M. A. (2015) · Psychiatry Research · doi:10.1016/j.psychres.2015.06.009 · Cited by 199

Endothelial Dysfunction: From Molecular Mechanisms to Measurement, Clinical Implications, and Therapeutic Opportunities

Brocq, M. L. L., Leslie, S. J., Milliken, P. H., & Megson, I. L. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.2013 · Cited by 196

High‐intensity interval and moderate‐intensity continuous training elicit similar enjoyment and adherence levels in overweight and obese adults

Vella, C. A., Taylor, K., & Drummer, D. J. (2017) · European Journal of Sport Science · doi:10.1080/17461391.2017.1359679 · Cited by 211

Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain: The Cardiovascular Health Study

Fornage, M., Chiang, Y. A., O'Meara, E. S., Psaty, B. M., Reiner, A. P., Siscovick, D. S., Tracy, R. P., & Longstreth, W. T. (2008) · Stroke · doi:10.1161/strokeaha.107.508135 · Cited by 187

Endogenous Reproductive Hormones and C-reactive Protein Across the Menstrual Cycle: The BioCycle Study

Gaskins, A. J., Wilchesky, M., Mumford, S. L., Whitcomb, B. W., Browne, R. W., Wactawski‐Wende, J., Perkins, N. J., & Schisterman, E. F. (2012) · American Journal of Epidemiology · doi:10.1093/aje/kwr343 · Cited by 193

Cardiac Disease in Chronic Obstructive Pulmonary Disease

Falk, J., Kadiev, S., Criner, G. J., Scharf, S. M., Minai, O. A., & Diaz, P. (2008) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200708-142et · Cited by 185

Effects of Statins on Nonlipid Serum Markers Associated with Cardiovascular Disease

Balk, E. M., Lau, J., Goudas, L. C., Jordan, H. S., Kupelnick, B., Kim, L. U., & Karas, R. H. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-139-8-200310210-00011 · Cited by 187

Homocysteine and reactive oxygen species in metabolic syndrome, type 2 diabetes mellitus, and atheroscleropathy: The pleiotropic effects of folate supplementation

Hayden, M. R., & Tyagi, S. C. (2004) · Nutrition Journal · doi:10.1186/1475-2891-3-4 · Cited by 183

Inflammation and Microvascular Dysfunction in Cardiac Syndrome X Patients Without Conventional Risk Factors for Coronary Artery Disease

Mayoral, A. R., Rimoldi, O. E., Camici, P. G., & Kaski, J. C. (2013) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2012.12.011 · Cited by 182

C-Reactive Protein Induces Matrix Metalloproteinase-1 and -10 in Human Endothelial Cells

Montero, I. D., Orbe, J., Varo, N., Beloqui, Ó., Monreal, J. I., Rodríguez, J. A., Dı́ez, J., Libby, P., & Páramo, J. A. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.10.070 · Cited by 181

Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro

Kleemann, R., Verschuren, L., de Rooij, B. F., Lindeman, J. H. N., de Maat, M. P. M., Szalai, A. J., Princen, H. M. G., & Kooistra, T. (2004) · Blood · doi:10.1182/blood-2003-11-3791 · Cited by 181

YKL-40, a biomarker of inflammation, is elevated in patients with type 2 diabetes and is related to insulin resistance

Rathcke, C. N., Johansen, J. S., & Vestergaard, H. (2006) · Inflammation Research · doi:10.1007/s00011-005-0010-8 · Cited by 182

Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo

Hein, T. W., Singh, U. S., Vasquez-Vivar, J. M., Devaraj, S., Kuo, L., & Jialal, I. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.02.002 · Cited by 176

Binding and Internalization of C-Reactive Protein by Fcgamma Receptors on Human Aortic Endothelial Cells Mediates Biological Effects

Devaraj, S., Clos, T. W. D., & Jialal, I. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000168573.10844.ae · Cited by 178

Mechanisms of Resolution of Inflammation: A Focus on Cardiovascular Disease

Maskrey, B. H., Megson, I. L., Whitfield, P. D., & Rossi, A. G. (2011) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.110.213850 · Cited by 177

Overview of hemostatic factors involved in atherosclerotic cardiovascular disease

Kannel, W. B. (2005) · Lipids · doi:10.1007/s11745-005-1488-8 · Cited by 177

Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy

Stark, K. D., & Holub, B. J. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.765 · Cited by 177

Plasma C-Reactive Protein and Risk of Cancer: A Prospective Study from Greece

Trichopoulos, D., Ψαλτοπούλου, Θ., Orfanos, P., Trichopoulou, A., & Boffetta, P. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0626 · Cited by 176

Uric Acid Levels Are Associated With All-Cause and Cardiovascular Disease Mortality Independent of Systemic Inflammation in Men From the General Population

Meisinger, C., Köenig, W., Baumert, J., & Döring, A. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.160184 · Cited by 173

Chemokines and Cardiovascular Risk

Aukrust, P., Halvorsen, B. L., Yndestad, A., Ueland, T., Øie, E., Otterdal, K., Gullestad, L. L., & Damås, J. K. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.161240 · Cited by 180

High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease

Rohrer, L., Hersberger, M., & von Eckardstein, A. (2004) · Current Opinion in Lipidology · doi:10.1097/00041433-200406000-00006 · Cited by 175

Chronic obstructive pulmonary disease and the risk of cardiovascular diseases

Schneider, C., Bothner, U., Jick, S. S., & Meier, C. R. (2010) · European Journal of Epidemiology · doi:10.1007/s10654-010-9435-7 · Cited by 172

C-Reactive protein as a biomarker for major depressive disorder?

Orsolini, L., Pompili, S., Tempia Valenta, S., Salvi, V., & Volpe, U. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031616 · Cited by 171

Depression and inflammation in patients with coronary heart disease: findings from the Heart and Soul Study

Whooley, M. A., Caska, C. M., Hendrickson, B. E., Rourke, M. A., Ho, J., & Ali, S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.10.016 · Cited by 171

Central obesity as a major determinant of increased high-sensitivity C-reactive protein in metabolic syndrome

Santos, A. C., Lopes, C. M. M., Guimarães, J. T., & Barros, H. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803035 · Cited by 174

Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases

Wagner, K., Wallner, M., Mölzer, C., Gazzin, S., Bulmer, A. C., Tiribelli, C., & Vítek, L. (2015) · Clinical Science · doi:10.1042/cs20140566 · Cited by 171

Multi-Omic Analysis of the Microbiome and Metabolome in Healthy Subjects Reveals Microbiome-Dependent Relationships Between Diet and Metabolites

Tang, Z.-Z., Chen, G., Hong, Q., Huang, S., Smith, H., Shah, R. D., Scholz, M. B., & Ferguson, J. F. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00454 · Cited by 175

Can Exercise Training With Weight Loss Lower Serum C-Reactive Protein Levels?

Okita, K., Nishijima, H., Murakami, T., Nagai, T., Morita, N., Yonezawa, K., Iizuka, K., Kawaguchi, H., & Kitabatake, A. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000140199.14930.32 · Cited by 169

Inflammation, Hypertension, and the Metabolic Syndrome

Grundy, S. M. (2003) · JAMA · doi:10.1001/jama.290.22.3000 · Cited by 170

C-Reactive Protein Levels and Survival in Patients With Moderate to Very Severe COPD

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