Clinical Application of C-Reactive Protein for Cardiovascular Disease Detection and Prevention

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

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Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

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C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus

Pradhan, A. D. (2001) · JAMA · doi:10.1001/jama.286.3.327 · Cited by 4,433

Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events

Ridker, P. M., Rifai, N., Rose, L., Buring, J. E., & Cook, N. R. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021993 · Cited by 3,604

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

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C-Reactive Protein, the Metabolic Syndrome, and Risk of Incident Cardiovascular Events: An 8-Year Follow-Up of 14 719 Initially Healthy American Women

Ridker, P. M., Buring, J. E., Cook, N. R., & Rifai, N. (2003) · Circulation · doi:10.1161/01.cir.0000055014.62083.05 · Cited by 2,292

C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men

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Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses

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Effect of Statin Therapy on C-Reactive Protein Levels

Albert, M. A., Danielson, E., Rifai, N., Ridker, P. M., & for the PRINCE Investigators (2001) · JAMA · doi:10.1001/jama.286.1.64 · Cited by 1,644

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

Ridker, P. M., Rifai, N., Clearfield, M., Downs, J. R., Weis, S. E., Miles, J. S., & Gotto, A. M. (2001) · New England Journal of Medicine · doi:10.1056/nejm200106283442601 · Cited by 1,557

Role of C-Reactive Protein at Sites of Inflammation and Infection

Sproston, N. R., & Ashworth, J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00754 · Cited by 3,243

The Metabolic Syndrome: Time for a Critical Appraisal

Kahn, R., Buse, J. B., Ferrannini, E., & Stern, M. P. (2005) · Diabetes Care · doi:10.2337/diacare.28.9.2289 · Cited by 2,400

Adipose Tissue, Inflammation, and Cardiovascular Disease

Berg, A. H., & Scherer, P. E. (2005) · Circulation Research · doi:10.1161/01.res.0000163635.62927.34 · Cited by 2,113

Recent advances in the relationship between obesity, inflammation, and insulin resistance.

Bastard, J., Maachi, M., Lagathu, C., Kim, M. J., Caron, M., Vidal, H., Capeau, J., & Fève, B. (2006) · PubMed · Cited by 2,090

Serum Procalcitonin and C-Reactive Protein Levels as Markers of Bacterial Infection: A Systematic Review and Meta-analysis

Simon, L., Gauvin, F., Amre, D. K., Saint-Louis, P., & Lacroix, J. (2004) · Clinical Infectious Diseases · doi:10.1086/421997 · Cited by 1,802

Psychological stress in childhood and susceptibility to the chronic diseases of aging: Moving toward a model of behavioral and biological mechanisms.

Miller, G. E., Chen, E., & Parker, K. J. (2011) · Psychological Bulletin · doi:10.1037/a0024768 · Cited by 1,785

Obesity, Metabolic Syndrome, and Cardiovascular Disease

Grundy, S. M. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0372 · Cited by 1,395

Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease

Nissen, S. E., Tuzcu, E. M., Schoenhagen, P., Crowe, T., Sasiela, W. J., Tsai, J., Orazem, J., Magorien, R. D., O'Shaughnessy, C., & Ganz, P. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa042000 · Cited by 1,325

Inflammation as a Cardiovascular Risk Factor

Willerson, J. T., & Ridker, P. M. (2004) · Circulation · doi:10.1161/01.cir.0000129535.04194.38 · Cited by 1,304

Mortality in COPD: role of comorbidities

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The vagus nerve and the inflammatory reflex – linking immunity and metabolism

Pavlov, V. A., & Tracey, K. J. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.189 · Cited by 1,040

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?: A Scientific Statement From the American Heart Association

Lockhart, P. B., Bolger, A. F., Papapanou, P. N., Osinbowale, O., Trevisan, M., Levison, M. E., Taubert, K. A., Newburger, J. W., Gornik, H. L., Gewitz, M. H., et al. (2012) · Circulation · doi:10.1161/cir.0b013e31825719f3 · Cited by 1,038

Myeloperoxidase Serum Levels Predict Risk in Patients With Acute Coronary Syndromes

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Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior

Haroon, E., Raison, C. L., & Miller, A. H. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.205 · Cited by 1,000

Adipokines: molecular links between obesity and atheroslcerosis

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Inflammation in Atherosclerosis: From Vascular Biology to Biomarker Discovery and Risk Prediction

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Genetically elevated C-reactive protein and ischemic vascular disease

Zacho, J., Tybjærg-Hansen, A., Jensen, J. S., Grande, P., Sillesen, H., & Nordestgaard, B. G. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0707402 · Cited by 839

Biological markers of oxidative stress: Applications to cardiovascular research and practice

Ho, E. C., Galougahi, K. K., Liu, C., Bhindi, R., & Figtree, G. A. (2013) · Redox Biology · doi:10.1016/j.redox.2013.07.006 · Cited by 835

Inflammatory Markers and Risk of Developing Type 2 Diabetes in Women

Hu, F. B., Meigs, J. B., Li, T. Y., Rifai, N., & Manson, J. E. (2004) · Diabetes · doi:10.2337/diabetes.53.3.693 · Cited by 788

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels

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Race and Gender Differences in C-Reactive Protein Levels

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National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 1—Full Report

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The role of TNF-α in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk

Popa, C. D., Netea, M. G., van Riel, P. L. C. M., van der Meer, J. W. M., & Stalenhoef, A. F. H. (2007) · Journal of Lipid Research · doi:10.1194/jlr.r600021-jlr200 · Cited by 781

New Markers of Inflammation and Endothelial Cell Activation: Part I

Szmitko, P. E., Wang, C.-H., Weisel, R. D., de Almeida, J. R., Anderson, T. J., & Verma, S. (2003) · Circulation · doi:10.1161/01.cir.0000089190.95415.9f · Cited by 738

Adipokines: The missing link between insulin resistance and obesity

Antuna-Puente, B., Fève, B., Fellahi, S., & Bastard, J. (2008) · Diabetes & Metabolism · doi:10.1016/j.diabet.2007.09.004 · Cited by 760

Acute-phase proteins: As diagnostic tool

Jain, S., Gautam, V., & Naseem, S. (2011) · Journal of Pharmacy And Bioallied Sciences · doi:10.4103/0975-7406.76489 · Cited by 684

Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

Mayers, J. R., Wu, C. H., Clish, C. B., Kraft, P. L., Torrence, M. E., Fiske, B. P., Yuan, C., Bao, Y., Townsend, M. K., Tworoger, S. S., et al. (2014) · Nature Medicine · doi:10.1038/nm.3686 · Cited by 672

Should C-Reactive Protein Be Added to Metabolic Syndrome and to Assessment of Global Cardiovascular Risk?

Ridker, P. M., Wilson, P. W. F., & Grundy, S. M. (2004) · Circulation · doi:10.1161/01.cir.0000132467.45278.59 · Cited by 645

Leukocyte count and coronary heart disease

Madjid, M., Awan, I., Willerson, J. T., & Casscells, S. W. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.07.056 · Cited by 654

C-reactive protein: Ligands, receptors and role in inflammation

Marnell, L. L., Mold, C., & Clos, T. W. D. (2005) · Clinical Immunology · doi:10.1016/j.clim.2005.08.004 · Cited by 625

Inflammation is associated with decreased functional connectivity within corticostriatal reward circuitry in depression

Felger, J. C., Li, Z., Haroon, E., Woolwine, B. J., Jung, M. Y., Hu, X., & Miller, A. H. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.168 · Cited by 620

Neuroendocrine-Immune Mechanisms of Behavioral Comorbidities in Patients With Cancer

Miller, A. H., Ancoli‐Israel, S., Bower, J. E., Capuron, L., & Irwin, M. R. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.10.7805 · Cited by 625

Alpha-linolenic acid and its conversion to longer chain n−3 fatty acids: Benefits for human health and a role in maintaining tissue n−3 fatty acid levels

Barceló‐Coblijn, G., & Murphy, E. J. (2009) · Progress in Lipid Research · doi:10.1016/j.plipres.2009.07.002 · Cited by 605

Inflammation and atherosclerosis: role of C-Reactive protein in risk assessment

Libby, P., & Ridker, P. M. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.02.006 · Cited by 601

Inflammatory/Antiinflammatory Properties of High-Density Lipoprotein Distinguish Patients From Control Subjects Better Than High-Density Lipoprotein Cholesterol Levels and Are Favorably Affected by Simvastatin Treatment

Ansell, B. J., Navab, M., Hama, S. Y., Kamranpour, N., Fonarow, G. C., Hough, G., Rahmani, S., Mottahedeh, R., Dave, R., Reddy, S. T., et al. (2003) · Circulation · doi:10.1161/01.cir.0000103624.14436.4b · Cited by 588

VITAMIN E, OXIDATIVE STRESS, AND INFLAMMATION

Singh, U. P., Devaraj, S., & Jialal, I. (2005) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.24.012003.132446 · Cited by 583

C-Reactive Protein: Risk Marker or Mediator in Atherothrombosis?

Jialal, I., Devaraj, S., & Venugopal, S. K. (2004) · Hypertension · doi:10.1161/01.hyp.0000130484.20501.df · Cited by 574

Endothelial Function Testing as a Biomarker of Vascular Disease

Verma, S., Buchanan, M. R., & Anderson, T. J. (2003) · Circulation · doi:10.1161/01.cir.0000089191.72957.ed · Cited by 575

Habitual Dietary Intake of n-3 and n-6 Fatty Acids in Relation to Inflammatory Markers Among US Men and Women

Pischon, T., Hankinson, S. E., Hotamisligil, G. S., Rifai, N., Willett, W. C., & Rimm, E. B. (2003) · Circulation · doi:10.1161/01.cir.0000079224.46084.c2 · Cited by 560

Effects of exercise and diet on chronic disease

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Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids

Adkins, Y. C., & Kelley, D. S. (2010) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2009.12.004 · Cited by 577

C-reactive Protein as a Predictor of Prognosis in Chronic Obstructive Pulmonary Disease

Dahl, M., Vestbo, J., Lange, P., Bojesen, S. E., Tybjærg‐Hansen, A., & Nordestgaard, B. G. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200605-713oc · Cited by 544

C-Reactive Protein and the Risk of Incident Colorectal Cancer

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Histopathologic Characteristics of Atherosclerotic Coronary Disease and Implications of the Findings for the Invasive and Noninvasive Detection of Vulnerable Plaques

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C-Reactive Protein Attenuates Endothelial Progenitor Cell Survival, Differentiation, and Function

Verma, S., Kuliszewski, M. A., Li, S.-H., Szmitko, P. E., Zucco, L., Wang, C., Badiwala, M., Mickle, D. A. G., Weisel, R. D., Fedak, P. W. M., et al. (2004) · Circulation · doi:10.1161/01.cir.0000127577.63323.24 · Cited by 527

Clinical Usefulness of Very High and Very Low Levels of C-Reactive Protein Across the Full Range of Framingham Risk Scores

Ridker, P. M., & Cook, N. R. (2004) · Circulation · doi:10.1161/01.cir.0000125690.80303.a8 · Cited by 516

Elevated C-Reactive Protein Levels, Psychological Distress, and Depression in 73 131 Individuals

Wium-Andersen, M. K., Ørsted, D. D., Nielsen, S. F., & Nordestgaard, B. G. (2013) · JAMA Psychiatry · doi:10.1001/2013.jamapsychiatry.102 · Cited by 489

Inflammatory processes in cardiovascular disease: a route to targeted therapies

Ruparelia, N., Chai, J. T., Fisher, E. A., & Choudhury, R. P. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.185 · Cited by 477

High-sensitivity C-reactive protein

Bassuk, S. S., Rifai, N., & Ridker, P. M. (2004) · Current Problems in Cardiology · doi:10.1016/s0146-2806(04)00074-x · Cited by 493

Obstructive Sleep Apnea

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Gut Microbiota and Inflammation

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Prevalence and sociodemographic correlates of antinuclear antibodies in the United States

Satoh, M., Chan, E. K. L., Ho, L. A., Rose, K. M., Parks, C. G., Cohn, R. D., Jusko, T. A., Walker, N. J., Germolec, D. R., Whitt, I. Z., et al. (2012) · Arthritis & Rheumatism · doi:10.1002/art.34380 · Cited by 452

Inflammation Effects on Motivation and Motor Activity: Role of Dopamine

Felger, J. C., & Treadway, M. T. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.143 · Cited by 474

What does plasma CRP tell us about peripheral and central inflammation in depression?

Felger, J. C., Haroon, E., Patel, T. A., Goldsmith, D. R., Wommack, E. C., Woolwine, B. J., Le, N.-A., Feinberg, R., Tansey, M. G., & Miller, A. H. (2020) · Molecular Psychiatry · doi:10.1038/s41380-018-0096-3 · Cited by 448

C-Reactive Protein: A Simple Test to Help Predict Risk of Heart Attack and Stroke

Ridker, P. M. (2003) · Circulation · doi:10.1161/01.cir.0000093381.57779.67 · Cited by 448

Exercise and Physical Activity: Clinical Outcomes and Applications

Kokkinos, P., & Myers, J. (2010) · Circulation · doi:10.1161/circulationaha.110.948349 · Cited by 444

C-Reactive Protein Modulates Risk Prediction Based on the Framingham Score

Köenig, W., Löwel, H., Baumert, J. J., & Meisinger, C. (2004) · Circulation · doi:10.1161/01.cir.0000120707.98922.e3 · Cited by 440

Raised CRP levels mark metabolic and functional impairment in advanced COPD

Broekhuizen, R. (2005) · Thorax · doi:10.1136/thx.2005.041996 · Cited by 441

The Cardiovascular Disease Continuum Validated: Clinical Evidence of Improved Patient Outcomes

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C-reactive protein in patients with COPD, control smokers and non-smokers

Pinto-Plata, V. (2005) · Thorax · doi:10.1136/thx.2005.042200 · Cited by 433

Imaging the Role of Inflammation in Mood and Anxiety-related Disorders

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A wellness study of 108 individuals using personal, dense, dynamic data clouds

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Established and Emerging Plasma Biomarkers in the Prediction of First Atherothrombotic Events

Ridker, P. M., Brown, N. J., Vaughan, D. E., Harrison, D. G., & Mehta, J. L. (2004) · Circulation · doi:10.1161/01.cir.0000133444.17867.56 · Cited by 420

Rosuvastatin in the Primary Prevention of Cardiovascular Disease Among Patients With Low Levels of Low-Density Lipoprotein Cholesterol and Elevated High-Sensitivity C-Reactive Protein

Ridker, P. M. (2003) · Circulation · doi:10.1161/01.cir.0000100688.17280.e6 · Cited by 424

Antiinflammatory Effects of Angiotensin II Subtype 1 Receptor Blockade in Hypertensive Patients With Microinflammation

Fliser, D., Buchholz, K., & Haller, H. G. (2004) · Circulation · doi:10.1161/01.cir.0000140265.21608.8e · Cited by 410

Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis

Kuo, H., Yen, C., Chang, C., Kuo, C.-K., Chen, J.-H., & Sorond, F. A. (2005) · The Lancet Neurology · doi:10.1016/s1474-4422(05)70099-5 · Cited by 409

The Clinical Significance and Potential Role of C-Reactive Protein in Chronic Inflammatory and Neurodegenerative Diseases

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Nonalcoholic Fatty Liver Disease Is Associated With Carotid Atherosclerosis

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Systemic low-grade inflammation is related to both circulating and adipose tissue TNFα, leptin and IL-6 levels in obese women

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Association Between C-Reactive Protein and Age-Related Macular Degeneration

Keenan, T. D. L., & Chew, E. Y. (2017) · International Journal of Research in Medical Sciences · doi:10.1001/jamaophthalmol.2017.2210 · Cited by 378

Association between C-reactive protein and age-related macular degeneration

Seddon, J. M. (2004) · JAMA · doi:10.1001/jama.291.6.704 · Cited by 376

Inflammatory Markers for Arterial Stiffness in Cardiovascular Diseases

Mozos, I. M., Malainer, C., Horbańczuk, J. O., Gug, C., Stoian, D. L., Luca, C. T., & Atanasov, A. G. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01058 · Cited by 395

The metabolic syndrome: time for a critical appraisal

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Erratum: Inflammatory processes in cardiovascular disease: a route to targeted therapies

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Guidelines for the management of arterial hypertension

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Effects of Fluticasone on Systemic Markers of Inflammation in Chronic Obstructive Pulmonary Disease

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Cytokines and Glucocorticoid Receptor Signaling

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The anti-inflammatory effects of exercise training in patients with type 2 diabetes mellitus

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C-Reactive Protein and Other Emerging Blood Biomarkers to Optimize Risk Stratification of Vulnerable Patients

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Increased C-Reactive Protein Levels in the Polycystic Ovary Syndrome: A Marker of Cardiovascular Disease

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Interleukin-18 and the Risk of Coronary Heart Disease in European Men

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Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in diet-induced metabolic syndrome

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The Role of Peripheral Inflammatory Markers in Dementia and Alzheimer's Disease: A Meta-Analysis

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Obesity is the major determinant of elevated C-reactive protein in subjects with the metabolic syndrome

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Promising Health Benefits of the Strawberry: A Focus on Clinical Studies

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