Cited by 3,162Lipoproteins and Cardiovascular HealthCardiovascular Health and Risk FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies.

Open access

Gordon, D J, Probstfield, J L, Garrison, R J, Neaton, J D, Castelli, W P, Knoke, J D, Jacobs, D R, Bangdiwala, S, Tyroler, H A·1989·Circulation

DOI 10.1161/01.cir.79.1.8

Open this paper in CoChat — free account Open PDF

Abstract

The British Regional Heart Study (BRHS) reported in 1986 that much of the inverse relation of high-density lipoprotein cholesterol (HDLC) and incidence of coronary heart disease was eliminated by covariance adjustment. Using the proportional hazards model and adjusting for age, blood pressure, smoking, body mass index, and low-density lipoprotein cholesterol, we analyzed this relation separately in the Framingham Heart Study (FHS), Lipid Research Clinics Prevalence Mortality Follow-up Study (LRCF) and Coronary Primary Prevention Trial (CPPT), and Multiple Risk Factor Intervention Trial (MRFIT). In CPPT and MRFIT (both randomized trials in middle-age high-risk men), only the control groups were analyzed. A 1-mg/dl (0.026 mM) increment in HDLC was associated with a significant coronary heart disease risk decrement of 2% in men (FHS, CPPT, and MRFIT) and 3% in women (FHS). In LRCF, where only fatal outcomes were documented, a 1-mg/dl increment in HDLC was associated with significant 3.7% (men) and 4.7% (women) decrements in cardiovascular disease mortality rates. The 95% confidence intervals for these decrements in coronary heart and cardiovascular disease risk in the four studies overlapped considerably, and all contained the range 1.9-2.9%. HDLC levels were essentially unrelated to non-cardiovascular disease mortality. When differences in analytic methodology were eliminated, a consistent inverse relation of HDLC levels and coronary heart disease event rates was apparent in BRHS as well as in the four American studies.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1161/01.cir.79.1.8

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
High density lipoprotein as a protective factor against coronary heart disease
Gordon, T., Castelli, W. P., Hjortland, M. C., Kannel, W. B., & Dawber, T. R. (1977) · The American Journal of Medicine · doi:10.1016/0002-9343(77)90874-9 · Cited by 5,059
Self-citation
Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia
Frick, M. H., Elo, O., Haapa, K., Heinonen, O. P., Heinsalmi, P., Helo, P., Huttunen, J. K., Kaitaniemi, P., Koskinen, P., Manninen, V., et al. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711123172001 · Cited by 3,881
A SIMPLIFIED METHOD FOR THE ESTIMATION OF TOTAL CHOLESTEROL IN SERUM AND DEMONSTRATION OF ITS SPECIFICITY
Abell, L. L., Levy, B. B., Brodie, B. B., & Kendall, F. E. (1952) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50907-3 · Cited by 3,085
Incidence of Coronary Heart Disease and Lipoprotein Cholesterol Levels
Castelli, W. P. (1986) · JAMA · doi:10.1001/jama.256.20.2835 · Cited by 2,512
Self-citation
Epidemiological approaches to heart disease: the Framingham study
Dawber, T. R., Meadors, G. F., & Moore, F. E. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.3.279 · Cited by 2,148
Beneficial Effects of Combined Colestipol-Niacin Therapy on Coronary Atherosclerosis and Coronary Venous Bypass Grafts
Blankenhorn, D. H. (1987) · JAMA · doi:10.1001/jama.1987.03390230069027 · Cited by 1,654
High density lipoprotein metabolism.
Eisenberg, S. (1984) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37713-0 · Cited by 1,212

Flagged first, then by citations

Show all 27 references

Research works printed but not linked: 8

Miller NE, Forde OH, Thelle DS, Mjos OD: The Tromso Heart Study: High-density lipoprotein and coronary heart disease: A prospective case-control study. Lancet 1977; 1:965-970
Gordon DJ, Knoke J, Probstfield JL, Superko R, Tyroler HA (for the Lipid Research Clinics Program): High-density lipoprotein cholesterol and coronary heart disease in hyper- cholesterolemic men: The Lipid Research Clinics Coronary Primary Prevention Trial. Circulation 1986;74:1217-1225
The Lipid Research Clinics Program Epidemiology Commit- tee: Plasma Lipid Distribution in Selected North American Populations: The Lipid Research Clinics Program Preva- lence Study. Circulation 1979;60:427-439
The Lipid Research Clinics Program: The Coronary Primary Prevention Trial: Design and implementation. J Chronic Dis 1979;32:609-631
The Lipid Research Clinics Program: The Lipid Research Clinics Coronary Primary Prevention Trial Results: I. Reduc- tion in incidence of coronary heart disease. JA1M 1984; 251:351-364
The Multiple Risk Factor Intervention Trial Group: Statisti- cal design considerations in the NHLBI Multiple Risk Fac- tor Intervention Trial (MRFIT). J Chronic Dis 1977; 30:261-275
Multiple Risk Factor Intervention Trial Research Group: Multiple Risk Factor Intervention Trial: Risk factor changes and mortality results. JAMA 1982;248:1465-1477
Shestov DB: Results of four years of follow-up of USSR populations, in USA-USSR First Lipoprotein Symposium. US Department of Health and Human Services Publication (NIH) 83-1966, Bethesda, Md, 1982, pp 391-407

Sorted by citations

Items 801–900 of 1,007

Apolipoprotein A-I Zavalla (Leu 159 →Pro)
Miller, M. J., Aiello, D. P., Pritchard, H., Friel, G., & Zeller, K. I. (1998) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.18.8.1242 · Cited by 51
High-density lipoprotein cholesterol and coronary artery disease: Survey of the evidence
Rifkind, B. M. (1990) · The American Journal of Cardiology · doi:10.1016/0002-9149(90)90561-e · Cited by 52
Indications for low-density lipoprotein apheresis.
Gordon, B. R., Stein, E. A., Jones, P. H., & Illingworth, D. (1994) · American Journal of Cardiology · doi:10.1016/0002-9149(94)90461-8 · Cited by 49
Quantitative Trait Locus Analysis of Plasma Lipoprotein Levels in an Autoimmune Mouse Model
Gu, L., Johnson, M. W., & Lusis, A. J. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.2.442 · Cited by 52
Biochemical characterization of the three major subclasses of lipoprotein A-I preparatively isolated from human plasma
Duverger, N., Rader, D. J., Duchateau, P. N., Fruchart, J., Castro, G. R., & Brewer, H. B. (1993) · Biochemistry · doi:10.1021/bi00097a014 · Cited by 52
The Role of High-Density Lipoprotein Cholesterol in 2022
Sirtori, C. R., Corsini, A., & Ruscica, M. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01012-y · Cited by 55
Increased age, high body mass index and low HDL‐C levels are related to an echolucent carotid intima–media: the METEOR study
Peters, S. A. E., Lind, L., Palmer, M. K., Grobbee, D. E., Crouse, J. R., O’Leary, D. H., Evans, G., Raichlen, J. S., Bots, M. L., den Ruijter, H. M., et al. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2011.02505.x · Cited by 51
Acute Coronary Syndrome Remodels the Protein Cargo and Functions of High-Density Lipoprotein Subfractions
Tan, Y., Liu, T. R., Hu, S. W., Tian, D., Li, C., Zhong, J. K., Sun, H. G., Luo, T., Lai, W. Y., & Guo, Z. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094264 · Cited by 51
Menopausa e síndrome metabólica
Meirelles, R. M. R. (2014) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/0004-2730000002909 · Cited by 52
Validation of the Antidiabetic and Hypolipidemic Effects of Hawthorn by Assessment of Gluconeogenesis and Lipogenesis Related Genes and AMP-Activated Protein Kinase Phosphorylation
Shih, C., Lin, C., Lin, Y.-J., & Wu, J. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/597067 · Cited by 51
Cholesteryl Ester Transfer Protein in Metabolic Syndrome
Sandhofer, A., Kaser, S., Ritsch, A., Laimer, M. W., Engl, J., Paulweber, B., Patsch, J. R., & Ebenbichler, C. F. (2006) · Obesity · doi:10.1038/oby.2006.94 · Cited by 51
Comparison of Effects of Simvastatin Alone Versus Fenofibrate Alone Versus Simvastatin Plus Fenofibrate on Lipoprotein Subparticle Profiles in Diabetic Patients With Mixed Dyslipidemia (from the Diabetes and Combined Lipid Therapy Regimen Study)
May, H. T., Anderson, J. L., Pearson, R. R., Jensen, J. R., Horne, B. D., Lavasani, F., Yannicelli, H. D., & Muhlestein, J. B. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.09.095 · Cited by 51
HDL-apolipoprotein A-I exchange is independently associated with cholesterol efflux capacity
Borja, M. S., Ng, K. F., Irwin, A. D., Hong, J., Wu, X., Isquith, D. A., Zhao, X.-Q., Prazen, B. J., Gildengorin, V. L., Oda, M. N., et al. (2015) · Journal of Lipid Research · doi:10.1194/jlr.m059865 · Cited by 51
Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro
Song, Q., Zhang, Y., Han, X., Zhang, Y., Zhang, X., Gao, Y., Zhang, J., Chu, L., & Zhao, S. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.10.147 · Cited by 52
Effect of Standardized Grape Powder Consumption on the Gut Microbiome of Healthy Subjects: A Pilot Study
Yang, J., Kurnia, P. T., Henning, S. M., Lee, R., Huang, J., Garcia, M. C., Surampudi, V., Heber, D., & Li, Z. (2021) · Nutrients · doi:10.3390/nu13113965 · Cited by 54
Preβ high density lipoprotein has two metabolic fates in human apolipoprotein A-I transgenic mice
Lee, J., Lanningham‐Foster, L., Boudyguina, E. Y., Smith, T. L., Young, E. R., Colvin, P. L., Thomas, M. J., & Parks, J. S. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300422-jlr200 · Cited by 51
Haplotypes of the cholesteryl ester transfer protein gene predict lipid-modifying response to statin therapy
Winkelmann, B. R., Hoffmann, M. M., Nauck, M., Kumar, A., Nandabalan, K., Judson, R., Boehm, B. O., Tall, A. R., Ruaño, G., & März, W. (2003) · The Pharmacogenomics Journal · doi:10.1038/sj.tpj.6500195 · Cited by 51
Changes in lipid profiles of rats fed with seaweed-based diets
Wong, K., Sam, S. W., Cheung, P. C. K., & Ang, P. O. (1999) · Nutrition Research · doi:10.1016/s0271-5317(99)00108-6 · Cited by 51
Effect of alcohol and exercise on postprandial lipemia and triglyceride clearance in men
Hartung, G. H., Lawrence, S. J., Reeves, R. S., & Foreyt, J. P. (1993) · Atherosclerosis · doi:10.1016/0021-9150(93)90065-3 · Cited by 51
Impact of total and central obesity on vascular mortality in patients undergoing coronary angiography
Hoefle, G., Saely, C. H., Aczél, S., Benzer, W., Marte, T., Langer, P. H., & Drexel, H. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0802985 · Cited by 49
Effect of Serum Lipids, Lipoproteins, and Apolipoproteins on Vascular and Nonvascular Mortality in the Elderly
Räihä, I. J., Marniemi, J., Puukka, P. J., Toikka, T., Ehnholm, C., & Sourander, L. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.7.1224 · Cited by 51
Association of alcohol consumption with lipid profile in hypertensive men
Park, H., & Kim, K. (2012) · Alcohol and Alcoholism · doi:10.1093/alcalc/ags019 · Cited by 50
Familial aggregation of blood lipid response to exercise training in the health, risk factors, exercise training, and genetics (HERITAGE) Family Study.
Rice, T., Després, J.-P., Pérusse, L., Hong, Y., Province, M. A., Bergeron, J., Gagnon, J., Leon, A. S., Skinner, J. S., Wilmore, J. H., et al. (2002) · Circulation · doi:10.1161/01.cir.0000014969.85364.9f · Cited by 65
Atherosclerosis: Immune and Inflammatory Aspects
Reiss, A. B., & Glass, A. D. (2006) · Journal of Investigative Medicine · doi:10.2310/6650.2006.05051 · Cited by 50
Effects of vitamin D supplementation on 25-hydroxyvitamin D, high-density lipoprotein cholesterol, and other cardiovascular disease risk markers in subjects with elevated waist circumference
Maki, K. C., Rubin, M. R., Wong, L. G., McManus, J. F., Jensen, C. D., & Lawless, A. L. (2011) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2010.536146 · Cited by 50
Red clover extract
Mueller, M., Hobiger, S., & Jungbauer, A. (2010) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3181c94617 · Cited by 51
Dietary carbohydrates, glycemic load and serum high-density lipoprotein cholesterol concentrations among South Indian adults
Radhika, G., Ganesan, A., Sathya, R. M., Sudha, V., & Mohan, V. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602951 · Cited by 50
High-Density Lipoprotein Particles, Cell-Cholesterol Efflux, and Coronary Heart Disease Risk
Asztalos, B. F., Horvath, K. V., & Schaefer, E. J. (2018) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.118.311117 · Cited by 50
Current Therapies Focused on High-Density Lipoproteins Associated with Cardiovascular Disease
Estrada-Luna, D., Ortiz-Rodríguez, M. A., Medina-Briseño, L., Carreón‐Torres, E., Vega, J. A. I., Sharma, A. K., Cancino‐Díaz, J. C., Pérez-Méndez, O. A., Belefant‐Miller, H., & Cabrera, G. B. (2018) · Molecules · doi:10.3390/molecules23112730 · Cited by 51
Very high high-density lipoprotein cholesterol is associated with increased all-cause mortality in South Koreans
Oh, I., Hur, J. K., Ryoo, J., Jung, J. Y., Park, S. K., Yang, H. J., Choi, J., Jung, K., Won, Y., & Oh, C. (2019) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2019.01.035 · Cited by 50
Excess coronary artery disease risk in South Asian immigrants: Can dysfunctional high-density lipoprotein explain increased risk?
Dodani, S. (2008) · Vascular Health and Risk Management · doi:10.2147/vhrm.s2915 · Cited by 49
Effects of combination lipid therapy on coronary stenosis progression and clinical cardiovascular events in coronary disease patients with metabolic syndrome: a combined analysis of the Familial Atherosclerosis treatment study (FATS), the HDL-Atherosclerosis treatment study (HATS) and the Armed Forces regression Study (AFREGS)
Zhao, X.-Q., Krasuski, R. A., Baer, J., Whitney, E. J., Neradilek, B., Chait, A., Marcovina, S., Albers, J. J., & Brown, B. G. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.07.035 · Cited by 48
Effects of taurine on serum cholesterol levels and development of atherosclerosis in spontaneously hyperlipidaemic mice
Matsushima, Y., Sekine, T., Kondo, Y., Sakurai, T., Kameo, K., Tachibana, M., & Murakami, S. (2003) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2003.03828.x · Cited by 49
Kiwifruit consumption favourably affects plasma lipids in a randomised controlled trial in hypercholesterolaemic men
Gammon, C. S., Kruger, R., Minihane, A. M., Conlon, C. A., von Hurst, P. R., & Stonehouse, W. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512004400 · Cited by 49
Regulation of Endothelial Nitric Oxide Synthase and High-Density Lipoprotein Quality by Estradiol in Cardiovascular Pathology
Kypreos, K. E., Zafirovic, S. S., Πετροπούλου, Π.-Ι., Bjelogrlic, P., Resanović, I., TRAISH, A. M., & Isenović, E. R. (2014) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248413513499 · Cited by 49
Mendelian Disorders of High-Density Lipoprotein Metabolism
Oldoni, F., Sinke, R. J., & Kuivenhoven, J. A. (2014) · Circulation Research · doi:10.1161/circresaha.113.300634 · Cited by 49
Effect of whole milk compared with skimmed milk on fasting blood lipids in healthy adults: a 3-week randomized crossover study
Engel, S., Elhauge, M., & Tholstrup, T. (2017) · European Journal of Clinical Nutrition · doi:10.1038/s41430-017-0042-5 · Cited by 49
The effect of honey consumption compared with sucrose on lipid profile in young healthy subjects (randomized clinical trial)
Rasad, H., Entezari, M. H., Ghadiri, E., Mahaki, B., & Pahlavani, N. (2018) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2018.04.016 · Cited by 49
Dapagliflozin reduces thrombin generation and platelet activation: implications for cardiovascular risk reduction in type 2 diabetes mellitus
Kohlmorgen, C., Gerfer, S., Feldmann, K., Twarock, S., Hartwig, S., Lehr, S., Klier, M., Krüger, I., Helten, C., Keul, P., et al. (2021) · Diabetologia · doi:10.1007/s00125-021-05498-0 · Cited by 49
Plasma lipids in Turkish children: impact of puberty, socioeconomic status, and nutrition on plasma cholesterol and HDL
Mahley, R. W., Arslan, P., Pekcan, A. G., Pépin, G. M., Ağaçdiken, A., Karaağaoğlu, N., Rakıcıoğlu, N., Tosun, B. N., Dayanıklı, P., Palaoğlu, K. E., et al. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31528-5 · Cited by 48
Three generations of high-density lipoprotein cholesterol assays compared with ultracentrifugation/dextran sulfate–Mg2+ method
Harris, N., Galpchian, V., Thomas, J. S., Iannotti, E., Law, T., & Rifai, N. (1997) · Clinical Chemistry · doi:10.1093/clinchem/43.5.816 · Cited by 49
The Effect of Hormone Replacement Therapy and Exercise on Cardiovascular Disease Risk Factors in Postmenopausal Women
Haddock, B. L., Marshak, H. P. H., Mason, J. J., & Blix, G. (2000) · Sports Medicine · doi:10.2165/00007256-200029010-00004 · Cited by 49
Fetal and Maternal Lipoprotein Metabolism in Human Pregnancy Complicated by Type I Diabetes Mellitus1
Kilby, M. D., Neary, R. H., Mackness, M., & Durrington, P. N. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.5.4783 · Cited by 49
Low high-density lipoprotein cholesterol and cardiovascular disease: Risk reduction with statin therapy
Rosenson, R. S. (2006) · American Heart Journal · doi:10.1016/j.ahj.2005.03.049 · Cited by 50
Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk
Sharma, R. K. (2009) · Vascular Health and Risk Management · doi:10.2147/vhrm.s5684 · Cited by 50
The lipid-lowering effects of atorvastatin, a new HMG-CoA reductase inhibitor: results of a randomized, double-masked study.
Heinonen, T., Stein, E., Weiss, S., Mckenney, J., Davidson, M., Shurzinske, L., & Black, D. (1996) · Clinical Therapeutics · doi:10.1016/s0149-2918(96)80045-2 · Cited by 50
Epidemiology of HIV cardiac disease
Cotter, B. R. (2003) · Progress in Cardiovascular Diseases · doi:10.1053/pcad.2003.5 · Cited by 48
Dyslipidemia management update
Chang, Y., & Robidoux, J. (2017) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2017.04.005 · Cited by 50
Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models
Landowski, M., & Rickman, C. B. (2021) · Journal of Ocular Pharmacology and Therapeutics · doi:10.1089/jop.2021.0067 · Cited by 48
Nicotinic acid and the prevention of coronary artery disease
Digby, J. E., Lee, J., & Choudhury, R. P. (2009) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32832d3b9d · Cited by 48
Advanced chronic obstructive pulmonary disease is associated with high levels of high-density lipoprotein cholesterol
Reed, R. M., Iacono, A. T., DeFilippis, A. P., Eberlein, M. H., Girgis, R. E., & Jones, S. R. (2011) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2010.12.010 · Cited by 48
Drug Treatment of Hyperlipidaemia
Toth, P. P. (2010) · Drugs · doi:10.2165/10898610-000000000-00000 · Cited by 49
HDL Metabolism and CETP Inhibition
Barkowski, R. S., & Frishman, W. H. (2008) · Cardiology in Review · doi:10.1097/crd.0b013e31816a3b60 · Cited by 49
Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages*
Shrestha, E., Hussein, M., Savas, J. N., Ouimet, M., Barrett, T. J., Leone, S., Yates, J., Moore, K., Fisher, E., & Garabedian, M. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.726729 · Cited by 47
Optimizing Dyslipidemia Management for the Prevention of Cardiovascular Disease: a Focus on Risk Assessment and Therapeutic Options
Berman, A. N., & Blankstein, R. (2019) · Current Cardiology Reports · doi:10.1007/s11886-019-1175-z · Cited by 48
Effects of Fat-Modified Dairy Products on Blood Lipids in Humans in Comparison with Other Fats
Seidel, C., Deufel, T., & Jahreis, G. (2005) · Annals of Nutrition and Metabolism · doi:10.1159/000084176 · Cited by 49
Risk of cardiovascular events in patients at optimal values for combined lipid parameters
Stanek, E. J., Sarawate, C. A., Willey, V. J., Charland, S. L., & Cziraky, M. J. (2007) · Current Medical Research and Opinion · doi:10.1185/030079906x167660 · Cited by 47
Leukocyte ABCA1 gene expression is associated with fasting glucose concentration in normoglycemic men
Albrecht, C., Simon-Vermot, I., Elliott, J. I., Higgins, C. F., Johnston, D. G., & Valabhji, J. (2003) · Metabolism · doi:10.1016/j.metabol.2003.07.009 · Cited by 48
Metabolic syndrome: dietary interventions
Aude, Y. W., Mego, P. A., & Mehta, J. L. (2004) · Current Opinion in Cardiology · doi:10.1097/01.hco.0000134610.68815.05 · Cited by 48
A Novel Family-Based Intervention Trial to Improve Heart Health: FIT Heart
Mosca, L. J., Greenberger, H. M., Liao, M., Christian, A. H., Edelman, D. J., Aggarwal, B., & Öz, M. C. (2008) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.108.825786 · Cited by 48
Reaching goal in hypercholesterolaemia: dual inhibition of cholesterol synthesis and absorption with simvastatin plus ezetimibe
Daskalopoulou, S. S., & Mikhailidis, D. P. (2006) · Current Medical Research and Opinion · doi:10.1185/030079906x89856 · Cited by 48
Plasma post-heparin lipase activities in the HERITAGE family study: the reproducibility, gender differences, and associations with lipoprotein levels
Després, J., Gagnon, J., Bergeron, J., Couillard, C., Leon, A. S., Rao, D. C., Skinner, J. S., Wilmore, J. H., & Bouchard, C. (1999) · Clinical Biochemistry · doi:10.1016/s0009-9120(98)00106-4 · Cited by 48
Role of fibrates in reducing coronary risk: a UK Consensus
The UK HDL-C Consensus Group (2004) · Current Medical Research and Opinion · doi:10.1185/030079903125002892 · Cited by 48
The Effects of Smoking on the Diagnostic Characteristics of Metabolic Syndrome: A Review
Behl, T. A., STAMFORD, B. A., & Moffatt, R. J. (2022) · American Journal of Lifestyle Medicine · doi:10.1177/15598276221111046 · Cited by 54
Protective effect of an endothelial lipase gene variant on coronary artery disease in a Chinese population
Tang, N., Wang, L., Yang, L., Zhou, B., Gu, H., Sun, Q., Cong, R.-H., Zhu, H., & Wang, B. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700399-jlr200 · Cited by 47
A Pro-Atherogenic HDL Profile in Coronary Heart Disease Patients: An iTRAQ Labelling-Based Proteomic Approach
Yan, L., Wang, D.-X., Liu, H., Zhang, X.-X., Zhao, H., Hua, L., Xu, P., & Li, Y. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098368 · Cited by 47
Beneficial effect of 1-year etanercept treatment on the lipid profile in responding patients with rheumatoid arthritis: the ETRA study
Jamnitski, A., Visman, I. M., Peters, M. J. L., Dijkmans, B. A. C., Voskuyl, A. E., & Nurmohamed, M. T. (2010) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2009.127597 · Cited by 47
Small high-density lipoprotein is associated with monocyte subsets in stable coronary artery disease
Krychtiuk, K. A., Kastl, S., Pfaffenberger, S., Pongratz, T., Hofbauer, S. L., Wonnerth, A., Katsaros, K. M., Goliasch, G., Gašpar, Ľ., Huber, K., et al. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.10.015 · Cited by 48
Current concept of reverse cholesterol transport and novel strategy for atheroprotection
Ono, K. (2012) · Journal of Cardiology · doi:10.1016/j.jjcc.2012.07.014 · Cited by 49
Dysfunctional High-Density Lipoproteins in Type 2 Diabetes Mellitus: Molecular Mechanisms and Therapeutic Implications
Bonilha, I., Zimetti, F., Zanotti, I., Papotti, B., & Sposito, A. C. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10112233 · Cited by 48
Raising HDL cholesterol in women
Merchant, N. (2009) · International Journal of Women s Health · doi:10.2147/ijwh.s5110 · Cited by 48
Description of Clinical Risk Factor Changes During Naturopathic Care for Type 2 Diabetes
Bradley, R. D., Kozura, E., Buckle, H., Kaltunas, J., Tais, S., & Standish, L. J. (2009) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2008.0249 · Cited by 47
Structural and functional changes in HDL with low grade and chronic inflammation
O'Neill, F., Riwanto, M., Charakida, M., Colin, S., Manz, J., McLoughlin, E., Khan, T. A., Klein, N. J., Kay, C. W. M., Patel, K., et al. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.03.058 · Cited by 47
Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL
Mulya, A., Lee, J., Gebre, A. K., Boudyguina, E. Y., Chung, S.-K., Smith, T. L., Colvin, P. L., Jiang, X.-C., & Parks, J. S. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800241-jlr200 · Cited by 48
Prevalence of Low HDL-Cholesterol Levels and Associated Factors Among Koreans
Kim, S. M., Han, J. H., & Park, H. S. (2006) · Circulation Journal · doi:10.1253/circj.70.820 · Cited by 47
Beyond LDL-C – The Importance of Raising HDL-C
Wierzbicki, A. S., & Mikhailidis, D. P. (2002) · Current Medical Research and Opinion · doi:10.1185/030079902125000165 · Cited by 47
Association of high-density-lipoprotein cholesterol with mortality and other risk factors for major chronic noncommunicable diseases in samples of US and Russian men
Nv, P., Оганов, Р. Г., Williams, D. H., Irving, S. H., Abernathy, J. R., Деев, А. Д., Шестов, Д. Б., Zhukovsky, G., DAVIS, C. E., & Tyroler, H. A. (1995) · Annals of Epidemiology · doi:10.1016/1047-2797(94)00104-2 · Cited by 47
Self-citation
Free radicals promote modifications in plasma high-density lipoprotein: Nuclear magnetic resonance analysis
Bradamante, S., Barenghi, L., Giudici, G. A., & Vergani, C. (1992) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(92)90027-e · Cited by 47
Atorvastatin in the Treatment of Primary Hypercholesterolemia and Mixed Dyslipidemias
Yee, H. S., & Fong, N. T. (1998) · Annals of Pharmacotherapy · doi:10.1345/aph.17231 · Cited by 47
Effects of moderate (MF) versus lower fat (LF) diets on lipids and lipoproteins: a meta-analysis of clinical trials in subjects with and without diabetes
Cao, Y., Mauger, D. T., Pelkman, C. L., Zhao, G., Townsend, S. M., & Kris-Etherton, P. M. (2009) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2008.12.008 · Cited by 46
Differing effects of aging on central and peripheral blood pressures and pulse wave velocity: a direct intraarterial study
Choi, C. U., Kim, E. J., Kim, S. H., Shin, S. Y., Choi, U.-J., Kim, J. W., Lim, H. E., Rha, S., Park, C. G., Seo, H. S., et al. (2010) · Journal of Hypertension · doi:10.1097/hjh.0b013e328337dad6 · Cited by 46
Cardiovascular disease in women: Sex differences in presentation, risk factors, and evaluation
Polk, D. M., & Naqvi, T. Z. (2005) · Current Cardiology Reports · doi:10.1007/s11886-005-0072-9 · Cited by 46
Recognizing and Improving Health Care Disparities in the Prevention of Cardiovascular Disease in Women
Jarvie, J. L., & Foody, J. M. (2010) · Current Cardiology Reports · doi:10.1007/s11886-010-0135-4 · Cited by 46
MRI-measured regression of carotid atherosclerosis induced by statins with and without niacin in a randomised controlled trial: the NIA plaque study
Sibley, C. T., Vavere, A. L., Gottlieb, I., Cox, C., Matheson, M. B., Spooner, A. E., Godoy, G., Fernandes, V., Wasserman, B. A., Bluemke, D. A., et al. (2013) · Heart · doi:10.1136/heartjnl-2013-303926 · Cited by 46
Diet Quality and Biomarker Profiles Related to Chronic Disease Prevention: The Multiethnic Cohort Study
Guillermo, C., Boushey, C. J., Franke, A. A., Monroe, K. R., Lim, U., Wilkens, L. R., Marchand, L. L., & Maskarinec, G. (2019) · Journal of the American College of Nutrition · doi:10.1080/07315724.2019.1635921 · Cited by 44
Correlates of high HDL cholesterol among women with coronary heart disease
Bittner, V., Simon, J. A., Fong, J., Blumenthal, R. S., Newby, L. K., & Stefanick, M. L. (2000) · American Heart Journal · doi:10.1016/s0002-8703(00)90238-2 · Cited by 46
Apolipoprotein A-II: Evaluating its significance in dyslipidaemia, insulin resistance, and atherosclerosis
Chan, D. C., Ng, T. W., & Watts, G. F. (2011) · Annals of Medicine · doi:10.3109/07853890.2011.573498 · Cited by 46
A Prospective Study of High-Density Lipoprotein Cholesterol, Cholesteryl Ester Transfer Protein Gene Variants, and Healthy Aging in Very Old Japanese-American Men
Koropatnick, T. A., Kimbell, J., Chen, R., Grove, J., Donlon, T. A., Masaki, K., Rodríguez, B. L., Willcox, B. J., Yano, K., & Curb, J. D. (2008) · The Journals of Gerontology Series A · doi:10.1093/gerona/63.11.1235 · Cited by 46
Paraoxonase-1 reduces monocyte chemotaxis and adhesion to endothelial cells due to oxidation of palmitoyl, linoleoyl glycerophosphorylcholine
Ahmed, Z. (2002) · Cardiovascular Research · doi:10.1016/s0008-6363(02)00659-4 · Cited by 46
High-density lipoprotein composition and paraoxonase activity in Type I diabetes
Valabhji, J., McColl, A. J., Schächter, M., Dhanjil, S. K., Richmond, W., & Elkeles, R. S. (2001) · Clinical Science · doi:10.1042/cs1010659 · Cited by 46
Relationship between physical activity and HDL-cholesterol in healthy older men and women: a cross-sectional and exercise intervention study
Fonong, T., Toth, M. J., Ades, P. A., Katzel, L. I., Calles-Escandón, J., & Poehlman, É. T. (1996) · Atherosclerosis · doi:10.1016/s0021-9150(96)05950-3 · Cited by 46
HDL: a recipe for longevity
Barter, P. J. (2004) · Atherosclerosis Supplements · doi:10.1016/j.atherosclerosissup.2004.03.003 · Cited by 46
Prevalence and correlates of alcohol use: a population‐based study in Hong Kong
Janghorbani, M., Ho, S. Y., Lam, T. H., & Janus, E. D. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00268.x · Cited by 46
Metabolism of ApoA-I as Lipid-Free Protein or as Component of Discoidal and Spherical Reconstituted HDLs
Kee, P. H., Rye, K., Taylor, J. L., Barrett, P. H. R., & Barter, P. J. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000038485.94020.7f · Cited by 46
Endocrine Responses to Chronic Androstenedione Intake in 30- to 56-Year-Old Men
Brown, G. A., Vukovich, M. D., Martini, E. R., Kohut, M. L., Franke, W. D., Jackson, D. A., & King, D. S. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.11.6940 · Cited by 49
Lipoprotein profile and cholesteryl ester transfer protein in neonates
Kaser, S., Ebenbichler, C. F., Wolf, H. J., Sandhofer, A., Stanzl, U., Ritsch, A., & Patsch, J. R. (2001) · Metabolism · doi:10.1053/meta.2001.23307 · Cited by 46
Design, Synthesis, and Biological Evaluation of Thio-Containing Compounds with Serum HDL-Cholesterol-Elevating Properties
Elokdah, H. M., Sulkowski, T. S., Abou-Gharbia, M. A., Butera, J. A., Chai, S., McFarlane, G. R., McKean, M., Babiak, J., Adelman, S. J., & Quinet, E. M. (2003) · Journal of Medicinal Chemistry · doi:10.1021/jm030219z · Cited by 46
Effect of Promoters and Enhancers on Expression, Transgene DNA Persistence, and Hepatotoxicity After Adenoviral Gene Transfer of Human Apolipoprotein A-I
Linthout, S. V., Collen, D., & Geest, B. D. (2002) · Human Gene Therapy · doi:10.1089/10430340252899000 · Cited by 47
Gene activation, apolipoprotein A-I/high density lipoprotein, atherosclerosis prevention and longevity.
Luoma, P. (1997) · Acta Pharmacologica et Toxicologica · doi:10.1111/j.1600-0773.1997.tb00032.x · Cited by 42
Atherosclerosis and HIV in the highly active antiretroviral therapy era
Mooser, V. (2003) · AIDS · doi:10.1097/00002030-200304001-00009 · Cited by 46

Authors: Gordon, D. J., Probstfield, J. L., Garrison, R. J., Neaton, J. D., Castelli, W. P., Knoke, J. D., Jacobs, D. R., Bangdiwala, S., & Tyroler, H. A.
Affiliations: National Institutes of Health (US)
ORCID: Probstfield, J L
Neaton, J D
Knoke, J D
Jacobs, D R
Bangdiwala, S
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1989-01
Volume: 79
Issue: 1
Pages: 8-15
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/01.cir.79.1.8
OpenAlex: W2077760013
Cited by: 3,162
References: 27
Citations by year: 2026: 35 · 2025: 41 · 2024: 62 · 2023: 69 · 2022: 90 · 2021: 90 · 2020: 90 · 2019: 84 · 2018: 96 · 2017: 87 · 2016: 81 · 2015: 125 · 2014: 137 · 2013: 125 · 2012: 129
FWCI: 61.95
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01hv012156-034)
National Heart, Lung, and Blood Institute (N01-HV32961, N01-HV 12156, N01-HV 12159)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: HDL cholesterol, coronary artery disease, cardiovascular mortality, inverse association, Framingham Heart Study, Multiple Risk Factor Intervention Trial, British Regional Heart Study, cardiovascular risk, sex differences
MeSH terms: Adult, Aged, Cardiovascular Diseases, Clinical Trials as Topic, Female, Humans, Cholesterol, HDL, Male, Middle Aged, Prospective Studies, Regression Analysis, Risk Factors, Sex Factors, Statistics as Topic, Cohort Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks