Cited by 3,162Lipoproteins and Cardiovascular HealthCardiovascular Health and Risk FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

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High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies.

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Gordon, D J, Probstfield, J L, Garrison, R J, Neaton, J D, Castelli, W P, Knoke, J D, Jacobs, D R, Bangdiwala, S, Tyroler, H A·1989·Circulation

DOI 10.1161/01.cir.79.1.8

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Abstract

The British Regional Heart Study (BRHS) reported in 1986 that much of the inverse relation of high-density lipoprotein cholesterol (HDLC) and incidence of coronary heart disease was eliminated by covariance adjustment. Using the proportional hazards model and adjusting for age, blood pressure, smoking, body mass index, and low-density lipoprotein cholesterol, we analyzed this relation separately in the Framingham Heart Study (FHS), Lipid Research Clinics Prevalence Mortality Follow-up Study (LRCF) and Coronary Primary Prevention Trial (CPPT), and Multiple Risk Factor Intervention Trial (MRFIT). In CPPT and MRFIT (both randomized trials in middle-age high-risk men), only the control groups were analyzed. A 1-mg/dl (0.026 mM) increment in HDLC was associated with a significant coronary heart disease risk decrement of 2% in men (FHS, CPPT, and MRFIT) and 3% in women (FHS). In LRCF, where only fatal outcomes were documented, a 1-mg/dl increment in HDLC was associated with significant 3.7% (men) and 4.7% (women) decrements in cardiovascular disease mortality rates. The 95% confidence intervals for these decrements in coronary heart and cardiovascular disease risk in the four studies overlapped considerably, and all contained the range 1.9-2.9%. HDLC levels were essentially unrelated to non-cardiovascular disease mortality. When differences in analytic methodology were eliminated, a consistent inverse relation of HDLC levels and coronary heart disease event rates was apparent in BRHS as well as in the four American studies.

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Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
Friedewald, W. T., Levy, R. I., & Fredrickson, D. S. (1972) · Clinical Chemistry · doi:10.1093/clinchem/18.6.499 · Cited by 32,423
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
High density lipoprotein as a protective factor against coronary heart disease
Gordon, T., Castelli, W. P., Hjortland, M. C., Kannel, W. B., & Dawber, T. R. (1977) · The American Journal of Medicine · doi:10.1016/0002-9343(77)90874-9 · Cited by 5,059
Self-citation
Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia
Frick, M. H., Elo, O., Haapa, K., Heinonen, O. P., Heinsalmi, P., Helo, P., Huttunen, J. K., Kaitaniemi, P., Koskinen, P., Manninen, V., et al. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711123172001 · Cited by 3,881
A SIMPLIFIED METHOD FOR THE ESTIMATION OF TOTAL CHOLESTEROL IN SERUM AND DEMONSTRATION OF ITS SPECIFICITY
Abell, L. L., Levy, B. B., Brodie, B. B., & Kendall, F. E. (1952) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50907-3 · Cited by 3,085
Incidence of Coronary Heart Disease and Lipoprotein Cholesterol Levels
Castelli, W. P. (1986) · JAMA · doi:10.1001/jama.256.20.2835 · Cited by 2,512
Self-citation
Epidemiological approaches to heart disease: the Framingham study
Dawber, T. R., Meadors, G. F., & Moore, F. E. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.3.279 · Cited by 2,148
Beneficial Effects of Combined Colestipol-Niacin Therapy on Coronary Atherosclerosis and Coronary Venous Bypass Grafts
Blankenhorn, D. H. (1987) · JAMA · doi:10.1001/jama.1987.03390230069027 · Cited by 1,654
High density lipoprotein metabolism.
Eisenberg, S. (1984) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37713-0 · Cited by 1,212

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Research works printed but not linked: 8

Miller NE, Forde OH, Thelle DS, Mjos OD: The Tromso Heart Study: High-density lipoprotein and coronary heart disease: A prospective case-control study. Lancet 1977; 1:965-970
Gordon DJ, Knoke J, Probstfield JL, Superko R, Tyroler HA (for the Lipid Research Clinics Program): High-density lipoprotein cholesterol and coronary heart disease in hyper- cholesterolemic men: The Lipid Research Clinics Coronary Primary Prevention Trial. Circulation 1986;74:1217-1225
The Lipid Research Clinics Program Epidemiology Commit- tee: Plasma Lipid Distribution in Selected North American Populations: The Lipid Research Clinics Program Preva- lence Study. Circulation 1979;60:427-439
The Lipid Research Clinics Program: The Coronary Primary Prevention Trial: Design and implementation. J Chronic Dis 1979;32:609-631
The Lipid Research Clinics Program: The Lipid Research Clinics Coronary Primary Prevention Trial Results: I. Reduc- tion in incidence of coronary heart disease. JA1M 1984; 251:351-364
The Multiple Risk Factor Intervention Trial Group: Statisti- cal design considerations in the NHLBI Multiple Risk Fac- tor Intervention Trial (MRFIT). J Chronic Dis 1977; 30:261-275
Multiple Risk Factor Intervention Trial Research Group: Multiple Risk Factor Intervention Trial: Risk factor changes and mortality results. JAMA 1982;248:1465-1477
Shestov DB: Results of four years of follow-up of USSR populations, in USA-USSR First Lipoprotein Symposium. US Department of Health and Human Services Publication (NIH) 83-1966, Bethesda, Md, 1982, pp 391-407

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DiMarco, D. M., Missimer, A., Murillo, A. G., Lemos, B. S., Malysheva, O., Caudill, M. A., Blesso, C. N., & Fernández, M. L. (2017) · Lipids · doi:10.1007/s11745-017-4230-9 · Cited by 89
Apolipoprotein A-I Mimetic Peptides
Sherman, C. B., Peterson, S. J., & Frishman, W. H. (2010) · Cardiology in Review · doi:10.1097/crd.0b013e3181c4b508 · Cited by 92
Arrangement of Apolipoprotein A-I in Reconstituted High-Density Lipoprotein Disks: An Alternative Model Based on Fluorescence Resonance Energy Transfer Experiments
Tricerri, M. A., Agree, A. K. B., Sánchez, S. A., Bronski, J. C., & Jonas, A. (2001) · Biochemistry · doi:10.1021/bi002815q · Cited by 91
Coronary bypass surgery should not be offered to smokers.
Underwood, M. J., & Bailey, J. (1993) · BMJ · doi:10.1136/bmj.306.6884.1047 · Cited by 91
High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock
COCKERILL, G. W., McDonald, M. C., Mota‐Filipe, H., Cuzzocrea, S., Miller, N. E., & Thiemermann, C. (2001) · The FASEB Journal · doi:10.1096/fj.01-0075com · Cited by 90
Amount and Intensity of Physical Activity, Physical Fitness, and Serum Lipids in Men
Marrugat, J., Elosúa, R., Covas, M.-I., Balaguer, L. M., Rubiés-Prat, J., & the MARATHOM Investigators (1996) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a008786 · Cited by 90
Relationship of Endogenous Sex Hormones to Lipids and Blood Pressure in Mid-Aged Women
SHELLEY, J. M., Green, A. C., Smith, A. M. A., Dudley, E., Dennerstein, L., Hopper, J. L., & Burger, H. (1998) · Annals of Epidemiology · doi:10.1016/s1047-2797(97)00123-3 · Cited by 90
Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy Spanish population
Corella, D., Sáiz, C., Guillén, M., Portolés, O., Mulet, F., González, J. I., & Ordovás, J. M. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00477-3 · Cited by 90
A Comparison of Simvastatin and Atorvastatin up to Maximal Recommended Doses in a Large Multicenter Randomized Clinical Trial
Illingworth, D. R., Crouse, J. R., Hunninghake, D. B., Davidson, M., Escobar, I. D., Stalenhoef, A. F. H., Paragh, G., Ma, P. T. S., Liu, M., Melino, M. R., et al. (2001) · Current Medical Research and Opinion · doi:10.1185/03007990152005351 · Cited by 91
Different reactivities of high density lipoprotein2 subfractions with hepatic lipase.
Mowri, H., Patsch, W., Smith, L., Gotto, A. M., & Patsch, J. R. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40541-3 · Cited by 89
The ABCA1 Gene R230C Variant Is Associated with Decreased Risk of Premature Coronary Artery Disease: The Genetics of Atherosclerotic Disease (GEA) Study
Villarreal-Molina, M. T., Posadas‐Romero, C., Romero‐Hidalgo, S., Antúnez-Argüelles, E., Bautista-Grande, A., Vargas‐Alarcón, G., Kimura‐Hayama, E., Canizales‐Quinteros, S., Juárez-Rojas, J. G., Posadas‐Sánchez, R., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049285 · Cited by 90
Improvement in cholesterol metabolism in mice given chronic treatment of taurine and fed a high-fat diet
Murakami, S., Kondo-Ohta, Y., & Tomisawa, K. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00536-0 · Cited by 89
High-density lipoprotein subfractions
Silverman, D. I., Ginsburg, G. S., & Pasternak, R. C. (1993) · The American Journal of Medicine · doi:10.1016/0002-9343(93)90217-d · Cited by 88
Association of high-density lipoprotein subclasses and incident coronary heart disease: The Jackson Heart and Framingham Offspring Cohort Studies
Joshi, P. H., Toth, P. P., Lirette, S. T., Griswold, M. E., Massaro, J. M., Martin, S. S., Blaha, M. J., Kulkarni, K. R., Khokhar, A. A., Correa, A., et al. (2014) · European Journal of Preventive Cardiology · doi:10.1177/2047487314543890 · Cited by 91
The contribution of ApoB and ApoA1 measurements to cardiovascular risk assessment
Andrikoula, M., & McDowell, I. F. W. (2007) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2007.00714.x · Cited by 88
Altered Composition of High Density Lipoproteins in Women with the Polycystic Ovary Syndrome1
Rajkhowa, M., Neary, R. H., Kumpatla, P., Game, F. L., Jones, P. W., Obhrai, M. S., & Clayton, R. N. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.10.4318 · Cited by 88
High prevalence of low HDL-cholesterol in a pan-European survey of 8545 dyslipidaemic patients
Bruckert, É., Baccara‐Dinet, M. T., McCoy, F., & Chapman, J. (2005) · Current Medical Research and Opinion · doi:10.1185/030079905x74871 · Cited by 88
DIET AND HEART DISEASE
Gaziano, J. M., & Manson, J. E. (1996) · Cardiology Clinics · doi:10.1016/s0733-8651(05)70261-7 · Cited by 88
Chronic consumption of a low calorie, high polyphenol cranberry beverage attenuates inflammation and improves glucoregulation and HDL cholesterol in healthy overweight humans: a randomized controlled trial
Chew, B. P., Mathison, B. D., Kimble, L. L., McKay, D. L., Kaspar, K. L., Khoo, C., Chen, C. O., & Blumberg, J. B. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1643-z · Cited by 99
Prevalence and Management of Dyslipidemia in Korea: Korea National Health and Nutrition Examination Survey during 1998 to 2010
Roh, E., Ko, S., Kwon, H., Kim, N. H., Kim, J. H., Kim, C. S., Song, K., Won, J. C., Kim, D. J., Choi, S. H., et al. (2013) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2013.37.6.433 · Cited by 90
Lipid Profile Components and Risk of Ischemic Stroke
Willey, J. Z., Xu, Q., Boden-Albala, B. M., Paik, M. C., Moon, Y. P., Sacco, R. L., & Elkind, M. S. V. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.210 · Cited by 87
Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women
Kodama, S., Saito, K., Tanaka, S., Maki, M., Shimano, H., Ohashi, Y., Yamada, N., & Sone, H. (2017) · Cited by 87
Cholesterol Paradox in Patients with Paroxysmal Atrial Fibrillation
Annoura, M., Ogawa, M., Kumagai, K., Zhang, B., Saku, K., & Arakawa, K. (1999) · Cardiology · doi:10.1159/000006942 · Cited by 86
Incidence, risk factors for amputation among patients with diabetic foot ulcer in a Chinese tertiary hospital
Li, X., Xiao, T., Wang, Y., Gu, H., Liu, Z., Jiang, Y., Liu, Y., Zu-qian, L., Yang, X., Lan, Y., et al. (2011) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2011.03.014 · Cited by 87
Insulin resistance and risk factors for coronary heart disease
Laws, A., & Reaven, G. M. (1993) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(05)80245-9 · Cited by 87
Efficacy and safety of pravastatin in patients with primary hypercholesterolemia
Hunninghake, D. B., Mellies, M. J., Goldberg, A. C., Kuo, P. T., Kostis, J. B., Schrott, H. G., Insull, W., & Pan, H. (1990) · Atherosclerosis · doi:10.1016/0021-9150(90)90114-x · Cited by 86
The Andro Project: Physiological and Hormonal Influences of Androstenedione Supplementation in Men 35 to 65 Years Old Participating in a High-Intensity Resistance Training Program
Broeder, C. E., Quindry, J., Brittingham, K., Panton, L., Thomson, J., Appakondu, S., Breuel, K., Byrd, R., Douglas, J., Earnest, C., et al. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.20.3093 · Cited by 109
Stent as a Novel Technology for Coronary Artery Disease and Their Clinical Manifestation
Ullah, M., Wahab, A., Khan, S. U., Zaman, U., Rehman, K. U., Hamayun, S., Naeem, M., Ali, H. H. M., Riaz, T., Saeed, S., et al. (2022) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2022.101415 · Cited by 90
Genetic Analysis of 103 Candidate Genes for Coronary Artery Disease and Associated Phenotypes in a Founder Population Reveals a New Association between Endothelin-1 and High-Density Lipoprotein Cholesterol
Paré, G., Serre, D., Brisson, D., Anand, S. S., Montpetit, A., Tremblay, G., Engert, J. C., Hudson, T. J., & Gaudet, D. (2007) · The American Journal of Human Genetics · doi:10.1086/513286 · Cited by 86
Relationship between Mediterranean Diet Score and atherothrombotic risk: Findings from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994
Carter, S. J., Roberts, M. B., Salter, J., & Eaton, C. B. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.12.035 · Cited by 85
Sex Difference in High Density Lipoprotein Cholesterol in Six Countries
DAVIS, C. E., Williams, D. H., Оганов, Р. Г., Tao, S.-C., Rywik, S. L., Stein, Y., & Little, J. A. (1996) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a008686 · Cited by 85
Plant sterol esters lower plasma lipids and most carotenoids in mildly hypercholesterolemic adults
Judd, J. T., Baer, D. J., Chen, S. C., Clevidence, B. A., Muesing, R. A., Kramer, M., & Meijer, G. W. (2002) · Lipids · doi:10.1007/s11745-002-0861-y · Cited by 85
Dyslipidemia and Cardiovascular Disease in Women
Cífková, R., & Krajčoviechová, A. (2015) · Current Cardiology Reports · doi:10.1007/s11886-015-0609-5 · Cited by 86
The Helsinki Heart Study: Central Findings and Clinical Implications
Huttunen, J. K., Manninen, V., Mänttäri, M., Koskinen, P., Romo, M., Tenkanen, L., Heinonen, O. P., & Frick, M. H. (1991) · Annals of Medicine · doi:10.3109/07853899109148041 · Cited by 85
Nicotinic acid, alone and in combinations, for reduction of cardiovascular risk
Brown, B. G., & Zhao, X.-Q. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.02.039 · Cited by 84
Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: Results of the randomized, double-blind, placebo-controlled INEF study
Warnholtz, A., Wild, P. S., Ostad, M. A., Elsner, V., Stieber, F., Schinzel, R., Walter, U., Peetz, D., Lackner, K. J., Blankenberg, S., et al. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.08.003 · Cited by 84

Authors: Gordon, D. J., Probstfield, J. L., Garrison, R. J., Neaton, J. D., Castelli, W. P., Knoke, J. D., Jacobs, D. R., Bangdiwala, S., & Tyroler, H. A.
Affiliations: National Institutes of Health (US)
ORCID: Probstfield, J L
Neaton, J D
Knoke, J D
Jacobs, D R
Bangdiwala, S
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1989-01
Volume: 79
Issue: 1
Pages: 8-15
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/01.cir.79.1.8
OpenAlex: W2077760013
Cited by: 3,162
References: 27
Citations by year: 2026: 35 · 2025: 41 · 2024: 62 · 2023: 69 · 2022: 90 · 2021: 90 · 2020: 90 · 2019: 84 · 2018: 96 · 2017: 87 · 2016: 81 · 2015: 125 · 2014: 137 · 2013: 125 · 2012: 129
FWCI: 61.95
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01hv012156-034)
National Heart, Lung, and Blood Institute (N01-HV32961, N01-HV 12156, N01-HV 12159)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: HDL cholesterol, coronary artery disease, cardiovascular mortality, inverse association, Framingham Heart Study, Multiple Risk Factor Intervention Trial, British Regional Heart Study, cardiovascular risk, sex differences
MeSH terms: Adult, Aged, Cardiovascular Diseases, Clinical Trials as Topic, Female, Humans, Cholesterol, HDL, Male, Middle Aged, Prospective Studies, Regression Analysis, Risk Factors, Sex Factors, Statistics as Topic, Cohort Studies

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High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies.

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