Magnetic measurement of S-T and T-Q segment shifts in humans. Part I: early repolarization and left bundle branch block
Open accessAbstract
The direct-current magnetocardiogram not only shows the features usually seen on the electrocardiogram, but also shows the T-Q (baseline) shift due to cardiac injury current. The first direct-current magnetocardiogram measurements of the human heart are presented here. The hypothesis tested is that there is no injury current associated with the S-T shift seen in two electrocardiogram abnormalities: early repolarization, and left bundle branch block. The data from three typical early repolarization subjects and one typical left bundle branch block patient are presented. It is found, in each case, that although there is appreciable S-T shift, there is essentially no baseline shift on the direct-current magnetocardiogram. The absence of baseline shift proves that the S-T shifts in these cases are not "apparent" shifts, caused by a dc injury current which is interrupted during the S-T interval; instead, these are "true" S-T shifts caused by a current flowing only during systole, presumably due to an altered repolarization of the ventricles. It is also found that the direct-current magnetocardiogram does not have routine clinical application because of a practical problem. This is the presence of false baseline shifts due to noncardiac currents, mostly in the gastrointestinal tract, which could be suppressed in only about one-third of the subjects. However, the direct-current magnetocardiogram may be useful as a research tool, for clarifying the cause of the S-T shift in selected subjects.
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DC-MCG is clinically feasible, although requiring EMS.
“Unfortunately, although requiring EMS, DC-MCG is also clinically feasible (107)”
From Clinical magnetocardiography: the unshielded bet—past, present, and future (2023) · cites this paper as [107]
The Discussion explicitly says the dcMCG “cannot at this time be used as a clinical diagnostic tool” because false T-Q shifts could not be reliably suppressed in most subjects. The Magnetic Measurements section describes use of a magnetically shielded room, but that does not support the claim that dcMCG was clinically feasible. (LLM, conf=0.91)
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Experimental — accuracy not yet measuredMCG can provide additional diagnostic information not achievable with electrocardiography alone.
“although theory and experimental research suggest and confirm that it can provide additional diagnostic information not achievable with electrocardiography alone (1, 2, 4–6, 9, 16, 107).”
From Clinical magnetocardiography: the unshielded bet—past, present, and future (2023) · cites this paper as [107]
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Self-citation
- Authors
- Savard, P., Cohen, D., Lepeschkin, E., Cuffin, B. N., & Madias, J. E.
- ORCID
- Venue
- Circulation Research
- Published
- 1983-08
- Volume
- 53
- Issue
- 2
- Pages
- 264-273
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2137833623
- Cited by
- 43
- References
- 20
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 1 · 2019: 1 · 2018: 1 · 2013: 2
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Massachusetts Institute of Technology
- National Institutes of Health
- Natural Sciences and Engineering Research Council of Canada
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › ECG Monitoring and Analysis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- early repolarization, left bundle branch block, ventricular repolarization, electrocardiographic abnormalities
- MeSH terms
- Electrocardiography, Heart, Heart Diseases, Heart Function Tests, Humans, Magnetics, Myocardial Contraction
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