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T-lymphocyte Infiltration in Visceral Adipose Tissue: A Primary Event in Adipose Tissue Inflammation and the Development of Obesity-Mediated Insulin Resistance
Abstract
Background— Adipose tissue inflammation may play a critical role in the pathogenesis of insulin resistance (IR). The present study examined the role of lymphocytes in adipose tissue inflammation and IR. Methods and Results— In a mouse model of obesity-mediated IR, high-fat diet (HFD) induced IR already after 5 weeks, which was associated with a marked T-lymphocyte infiltration in visceral adipose tissue. In contrast, recruitment of macrophages was delayed with an increase of MAC3-positive staining and F4/80 mRNA expression after 10 weeks of HFD, suggesting a dissociation of macrophage invasion into adipose tissue and IR initiation. In patients with type 2 diabetes, lymphocyte content in adipose tissue biopsies significantly correlated with waist circumference, a marker of IR. Immunohistochemical staining of human adipose tissue revealed the presence of mainly CD4-positive lymphocytes as well as macrophage infiltration. Most macrophages were HLA-DR–positive, reflecting activation through IFNγ, a cytokine released from CD4-positive lymphocytes. Conclusions— Proinflammatory T-lymphocytes are present in visceral adipose tissue and may contribute to local inflammatory cell activation before the appearance of macrophages, suggesting that these cells could play an important role in the initiation and perpetuation of adipose tissue inflammation as well as the development of IR.
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“Serum or plasma concentrations of TNF-a or IL-6 in healthy adults are typically 0•01-2 pmol/l (6) .”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [6]
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Cites
Obesity is associated with macrophage accumulation in adipose tissue
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041
Inflammation, Atherosclerosis, and Coronary Artery Disease
Hansson, G. K. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043430 · Cited by 8,773
Inflammation and Atherosclerosis
Libby, P., Ridker, P. M., & Maseri, A. (2002) · Circulation · doi:10.1161/hc0902.104353 · Cited by 7,724
Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664
Interferon-γ: an overview of signals, mechanisms and functions
Schroder, K., Hertzog, P. J., Ravasi, T., & Hume, D. A. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0603252 · Cited by 4,120
Chemokines — Chemotactic Cytokines That Mediate Inflammation
Luster, A. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802123380706 · Cited by 3,633
Pouliot, M., Després, J., Lemieux, S., Moorjani, S., Bouchard, C., Tremblay, A., Nadeau, A., & Lupien, P. J. (1994) · The American Journal of Cardiology · doi:10.1016/0002-9149(94)90676-9 · Cited by 2,099
Obesity-induced inflammatory changes in adipose tissue
Wellen, K. E., & Hotamisligil, G. S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200320514 · Cited by 1,823
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
Weisberg, S. P., Hunter, D., Huber, R., Lemieux, J., Slaymaker, S., Vaddi, K., Charo, I., Leibel, R. L., & Jr., A. W. F. (2006) · Journal of Clinical Investigation · doi:10.1172/jci24335 · Cited by 1,497
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Items 301–400 of 689
Habanjar, O., Diab‐Assaf, M., Caldefie‐Chezet, F., & Delort, L. (2022) · Biology · doi:10.3390/biology11020339 · Cited by 41
Lucas, S., Taront, S., Magnan, C., Fauconnier, L., Delacre, M., Macia, L., Delanoye, A., Verwaerde, C., Spriet, C., Saule, P., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040351 · Cited by 40
Advances in T Cells Based on Inflammation in Metabolic Diseases
Yu, W., Li, C., Zhang, D., Li, Z., Xia, P., Liu, X., Cai, X., Yang, P., Ling, J., Zhang, J., et al. (2022) · Cells · doi:10.3390/cells11223554 · Cited by 41
Adaptive Immunity and Antigen‐Specific Activation in Obesity‐Associated Insulin Resistance
Chng, M. H. Y., Alonso, M. N., Barnes, S. E., Nguyen, K. D., & Engleman, E. G. (2015) · Mediators of Inflammation · doi:10.1155/2015/593075 · Cited by 39
Surmi, B. K., Webb, C. D., Ristau, A. C., & Hasty, A. H. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00050.2010 · Cited by 40
Anand, G., Vasanthakumar, R., Mohan, V., Babu, S., & Aravindhan, V. (2014) · Europe PMC (PubMed Central) · Cited by 39
Couturier, J. P., Agarwal, N., Nehete, P. N., Baze, W. B., Barry, M. A., Sastry, K. J., Balasubramanyam, A., & Lewis, D. E. (2016) · Retrovirology · doi:10.1186/s12977-016-0260-2 · Cited by 40
Immune Cells Gate White Adipose Tissue Expansion
Cox, A. R., Chernis, N., Masschelin, P. M., & Hartig, S. M. (2019) · Endocrinology · doi:10.1210/en.2019-00266 · Cited by 39
Obesity-induced inflammation and insulin resistance: A mini-review on T-cells
Nyambuya, T. M., Dludla, P. V., Mxinwa, V., & Nkambule, B. B. (2019) · Metabolism Open · doi:10.1016/j.metop.2019.100015 · Cited by 40
Trim, W. V., Walhin, J., Koumanov, F., Bouloumié, A., Lindsay, M. A., Chen, Y., Travers, R. L., Turner, J. E., & Thompson, D. (2021) · The Journal of Physiology · doi:10.1113/jp280977 · Cited by 41
Orchestration of the Adipose Tissue Immune Landscape by Adipocytes
Bradley, D. P., Deng, T., Shantaram, D., & Hsueh, W. A. (2024) · Annual Review of Physiology · doi:10.1146/annurev-physiol-042222-024353 · Cited by 44
RANTES and fibroblast growth factor 2 in jawbone cavitations: triggers for systemic disease?
Lechner, J., & von Baehr (2013) · International Journal of General Medicine · doi:10.2147/ijgm.s43852 · Cited by 38
Contributions of innate type 2 inflammation to adipose function
Bolus, W. R., & Hasty, A. H. (2018) · Journal of Lipid Research · doi:10.1194/jlr.r085993 · Cited by 42
CD4+ T cells in obesity and obesity-associated diseases
Zhao, Y., Lin, L., Li, J., Xiao, Z., Chen, B., Wan, L., Li, M., Wu, X., Cho, C. H., & Shen, J. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.08.013 · Cited by 38
The pharmacological management of patients with comorbid psoriasis and obesity
Chiricozzi, A., Gisondi, P., & Girolomoni, G. (2019) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2019.1583207 · Cited by 38
Abdominal Fat Mass Is Associated With Adaptive Immune Activation: The CODAM Study
Thewissen, M. M., Damoiseaux, J. G. M. C., Duijvestijn, A. M., van Greevenbroek, M. M. J., Kallen, C., Feskens, E. J. M., Blaak, E. E., Schalkwijk, C. G., Stehouwer, C. D. A., Tervaert, J. W. C., et al. (2011) · Obesity · doi:10.1038/oby.2010.337 · Cited by 39
Distinct Adipose Depots from Mice Differentially Respond to a High-Fat, High-Salt Diet
DeClercq, V., Goldsby, J. S., McMurray, D. N., & Chapkin, R. S. (2016) · Journal of Nutrition · doi:10.3945/jn.115.227496 · Cited by 37
SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes
Shin, J., Fukuhara, A., Onodera, T., Kita, S., Yokoyama, C., Otsuki, M., & Shimomura, I. (2018) · Diabetes · doi:10.2337/db17-0706 · Cited by 37
McGillicuddy, F. C., Reynolds, C. M., Finucane, O., Coleman, E., Harford, K. A., Grant, C., Sergi, D., Williams, L. M., Mills, K. H. G., & Roche, H. M. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00297.2013 · Cited by 36
Association of Common Genetic Variants in the MAP4K4 Locus with Prediabetic Traits in Humans
Sartorius, T., Staiger, H., Ketterer, C., Heni, M., Machicao, F. E., Guilherme, A., Grallert, H., Schulze, M. B., Boeing, H., Stefan, N., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047647 · Cited by 36
Koethe, J. R., McDonnell, W. J., Kennedy, A. J., Abana, C. O., Pilkinton, M. A., Setliff, I., Georgiev, I. S., Barnett, L. D., Hager, C. C., Smith, R. M., et al. (2017) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000001573 · Cited by 36
Lee, G. Y., Park, C. Y., Cha, K. S., Lee, S. E., Pae, M., & Han, S. N. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.01.004 · Cited by 37
From Influenza Virus to Novel Corona Virus (SARS-CoV-2)–The Contribution of Obesity
Bhattacharya, I., Ghayor, C., Domínguez, A. P., & Weber, F. E. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.556962 · Cited by 38
THP-1 Macrophages and SGBS Adipocytes ? A New Human in vitro Model System of Inflamed Adipose Tissue
Keuper, M., Dzyakanchuk, A. A., Amrein, K. E., Wabitsch, M., & Fischer‐Posovszky, P. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2011.00089 · Cited by 36
Self-citationZhang, S., Lv, Y., Zhang, H., Gao, S., Wang, T., Feng, J., Wang, Y., Liu, C., Xu, M., Wang, X., et al. (2016) · Diabetes · doi:10.2337/db15-1626 · Cited by 37
Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
Liao, X., Zeng, Q., Xie, L., Zhang, H., Hu, W., Xiao, L., Zhou, H., Wang, F., Xie, W., Song, J., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113963 · Cited by 35
Jacobsen, M. J., Mentzel, C. M. J., Olesen, A. S., Huby, T., Jørgensen, C. B., Barrès, R., Fredholm, M., & Simar, D. (2015) · Journal of Diabetes Research · doi:10.1155/2016/8539057 · Cited by 37
Okamura, T., Hashimoto, Y., Hamaguchi, M., Obora, A., Kojima, T., & Fukui, M. (2020) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2019.04.002 · Cited by 32
[Cells of innate and adaptive immunity in type 2 diabetes and obesity].
Guzmán‐Flores, J. M., & López-Briones, S. (2012) · PubMed · Cited by 34
CXCR3 Controls T-Cell Accumulation in Fat Inflammation
Rocha, V. Z., Folco, E. J. E., Ozdemir, C., Sheikine, Y., Christen, T., Sukhova, G. K., Tang, E. H. C., Bittencourt, M. S., Santos, R. D., Luster, A. D., et al. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.303133 · Cited by 34
The macrophage at the intersection of immunity and metabolism in obesity
Samaan, M. C. (2011) · Diabetology & Metabolic Syndrome · doi:10.1186/1758-5996-3-29 · Cited by 34
Characterization of immune cells in psoriatic adipose tissue
Rose, S. M., Stansky, E., Dagur, P. K., Samsel, L., Weiner, E., Jahanshad, A., Doveikis, J., Naik, H. B., Playford, M. P., McCoy, J. P., et al. (2014) · Journal of Translational Medicine · doi:10.1186/s12967-014-0258-2 · Cited by 34
Yu, D., Xu, Z., Yin, X., Zheng, F., Lin, X., Pan, Q., & Li, H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0142848 · Cited by 35
Cai, H. Q., Weickert, T. W., Catts, V. S., Balzan, R. P., Galletly, C. A., Liu, D., O׳Donnell, M., & Weickert, C. S. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.06.017 · Cited by 34
Th1/Th2 Balance in Young Subjects: Relationship with Cytokine Levels and Metabolic Profile
Matia‐García, I., Vadillo, E., Pelayo, R., Muñóz-Valle, J. F., García‐Chagollán, M., Loaeza‐Loaeza, J., Vences-Velázquez, A., Salgado-Goytia, L., García‐Arellano, S., & Parra‐Rojas, I. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s342545 · Cited by 36
Hagman, D. K., Kuzma, J. N., Larson, I. A., Foster‐Schubert, K. E., Kuan, L.-Y., Cignarella, A., Geamanu, E. D., Makar, K. W., Gottlieb, J. R., & Kratz, M. (2012) · Journal of Immunological Methods · doi:10.1016/j.jim.2012.08.018 · Cited by 34
Fu, C., Sheu, W. H., Lee, I., Tsai, I., Lee, W., Liang, K., Lee, W.-L., & Lin, S. (2013) · Clinica Chimica Acta · doi:10.1016/j.cca.2013.03.005 · Cited by 34
Insulin sensitivity in long-living Ames dwarf mice
Wiesenborn, D. S., Ayala, J. E., King, E. M., & Masternak, M. M. (2014) · AGE · doi:10.1007/s11357-014-9709-1 · Cited by 35
Busnelli, M., Manzini, S., Froio, A., Vargiolu, A., Cerrito, M. G., Smolenski, R. T., Giunti, M., Cinti, A., Zannoni, A., Leone, B. E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080588 · Cited by 33
In situ production of innate immune cells in murine white adipose tissue
Poglio, S., de Toni, F., Lewandowski, D., Minot, A., Arnaud, E., Barroca, V., Laharrague, P. F., Casteilla, L., & Cousin, B. (2012) · Blood · doi:10.1182/blood-2012-01-406959 · Cited by 33
Zhou, T., Wang, G., Lyu, Y., Wang, L., Zuo, S., Zou, J., Sun, L., Zhao, W., Shu, C., Yang, Y., et al. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1791-y · Cited by 33
Zhou, H., Peng, X., Hu, J., Wang, L., Luo, H., Zhang, J., Zhang, Y., Li, G., Ji, Y., Zhang, J., et al. (2021) · Nature Communications · doi:10.1038/s41467-020-20665-4 · Cited by 34
Adipose tissue and skeletal muscle plasticity modulates metabolic health
Ukropec, J., Ukropcová, B., Kurdiová, T., Gašperíková, D., & Klimeś, I. (2008) · Archives of Physiology and Biochemistry · doi:10.1080/13813450802535812 · Cited by 36
Therapeutic Potentials of Microalgae and Their Bioactive Compounds on Diabetes Mellitus
Tamel Selvan, K., Goon, J. A., Makpol, S., & Tan, J. K. (2023) · Marine Drugs · doi:10.3390/md21090462 · Cited by 32
Tibães, J. R. B., Silva, M. I. B., Wollin, B., Vine, D. F., Tsai, S. J., & Richard, C. (2023) · Obesity Reviews · doi:10.1111/obr.13665 · Cited by 32
The immune cell transcription factor T-bet: A novel metabolic regulator
Stolarczyk, E., Lord, G. M., & Howard, J. K. (2014) · Adipocyte · doi:10.4161/adip.26220 · Cited by 32
Bariatric surgery, adipose tissue and gut microbiota
Clément, K. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.141 · Cited by 33
Khalyfa, A., Gharib, S. A., Kim, J., Capdevila, Ó. S., Gozal, D., Bhattacharjee, R., Hegazi, M., & Gozal, D. (2011) · SLEEP · doi:10.1093/sleep/34.2.153 · Cited by 32
Turcotte, L. M., Yingst, A. M., & Verneris, M. R. (2016) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2016.03.016 · Cited by 30
Pae, M., Baek, Y., Lee, S., & Wu, D. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.03.011 · Cited by 31
Dwaib, H. S., AlZaim, I., Eid, A. H., Obeid, O., & EL‐Yazbi, A. F. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.626313 · Cited by 33
Dietary factors and low-grade inflammation in relation to overweight and obesity revisted
Calder, P. C. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522000782 · Cited by 32
MicroRNAs: a crossroad that connects obesity to immunity and aging
Rakib, A., Kiran, S., Mandal, M., & Singh, U. P. (2022) · Immunity & Ageing · doi:10.1186/s12979-022-00320-w · Cited by 35
Pignatelli, J., Castro, R., Granja, A. G., Abós, B., González, L., Jensen, L. B., & Tafalla, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110920 · Cited by 31
Romero, M. D. M., Fernández–Löpez, J., Esteve, M., & Alemany, M. (2009) · Cardiovascular Diabetology · doi:10.1186/1475-2840-8-42 · Cited by 31
Vick, L. V., Canter, R. J., Monjazeb, A. M., & Murphy, W. J. (2023) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2023.07.004 · Cited by 35
Markers of macrophage infiltration and measures of lipolysis in human abdominal adipose tissues
Michaud, A., Pelletier, M., Noël, S., Bouchard, C., & Tchernof, A. (2013) · Obesity · doi:10.1002/oby.20341 · Cited by 30
O’Rourke, R. W. (2009) · World Journal of Surgery · doi:10.1007/s00268-009-0067-6 · Cited by 30
OX40 promotes obesity-induced adipose inflammation and insulin resistance
Liu, B., Yu, H., Sun, G., Sun, X., Jin, H., Zhang, C., Shi, W., Tian, D., Liu, K., Xu, H., et al. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2552-7 · Cited by 30
Adipose tissue inflammation: are small or large fat cells to blame?
Hauner, H. (2009) · Diabetologia · doi:10.1007/s00125-009-1605-3 · Cited by 29
Self-citationInterleukin-17A Gene Expression in Morbidly Obese Women
Zapata-Gonzalez, F., Auguet, T., Aragonès, G., Guiu‐Jurado, E., Berlanga, A., Martínez, S., Martí, A., Sabench, F., Hernández, M., Aguilar, C., et al. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160817469 · Cited by 28
Clinical analysis of selected complement-derived molecules in human adipose tissue
Błogowski, W., Budkowska, M., Sałata, D., Serwin, K., Dołęgowska, B., Łokaj, M., Prowans, P., & Starzyñska, T. (2013) · Journal of Translational Medicine · doi:10.1186/1479-5876-11-11 · Cited by 28
Marzola, P., Boschi, F., Moneta, F., Sbarbati, A., & Zancanaro, C. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00336 · Cited by 33
The impact of body mass index on adaptive immune cells in the human bone marrow
Pangrazzi, L., Naismith, E., Miggitsch, C., Arana, J. A. C., Keller, M., Grubeck‐Loebenstein, B., & Weinberger, B. (2020) · Immunity & Ageing · doi:10.1186/s12979-020-00186-w · Cited by 28
Sbierski‐Kind, J., Mai, K., Kath, J., Jurisch, A., Streitz, M., Kuchenbecker, L., Babel, N., Nienen, M., Jürchott, K., Spranger, L., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000108 · Cited by 28
Visceral adiposity is associated with an increased risk of functional dyspepsia
Jung, J. G., Yang, J. N., Lee, C. G., Choi, S. H., Kwack, W. G., Lee, J. H., & Kang, H. W. (2015) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13146 · Cited by 28
Relationship between energy dense diets and white adipose tissue inflammation in metabolic syndrome
Alemany, M. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.11.013 · Cited by 28
Komorowski, J., Jankiewicz-Wika, J., Kołomecki, K., Cywiński, J. B., Piestrzeniewicz, K., Świętosławski, J., & Stepien, H. (2011) · Cytokine · doi:10.1016/j.cyto.2011.03.020 · Cited by 28
Anti-Inflammatory Diets for Obesity and Diabetes
Sears, B. (2009) · Journal of the American College of Nutrition · doi:10.1080/07315724.2009.10718115 · Cited by 27
Activation of adipose tissue macrophages in obese mice does not require lymphocytes
Behan, J. W., Ehsanipour, E. A., Sheng, X., Pramanik, R., Wang, X., Hsieh, Y., Kim, Y., & Mittelman, S. D. (2013) · Obesity · doi:10.1002/oby.20159 · Cited by 27
Guo, H., Xu, B., Yang, X., Peng, D., Wang, Y., Liu, X., Cui, C., & Jiang, Y. (2014) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.21821 · Cited by 27
LPS response pattern of inflammatory adipokines in an in vitro 3T3-L1 murine adipocyte model
Chirumbolo, S., Franceschetti, G., Zoico, E., Bambace, C., Cominacini, L., & Zamboni, M. M. (2014) · Inflammation Research · doi:10.1007/s00011-014-0721-9 · Cited by 27
Cardiovascular disease and diabetes: the vulnerable patient
Hess, K., Marx, N., & Lehrke, M. (2012) · European Heart Journal Supplements · doi:10.1093/eurheartj/sus002 · Cited by 28
Self-citationPoelkens, F., Lammers, G., Pardoel, E. M., Tack, C. J., & Hopman, M. T. E. (2013) · Experimental Physiology · doi:10.1113/expphysiol.2013.072710 · Cited by 27
Bisphenol AF promotes inflammation in human white adipocytes
Chernis, N., Masschelin, P. M., Cox, A. R., & Hartig, S. M. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00175.2019 · Cited by 26
Time-Restricted Feeding Restores Obesity-Induced Alteration in Adipose Tissue Immune Cell Phenotype
Lee, Y., Kim, Y., Lee, M., Wu, D., & Pae, M. (2021) · Nutrients · doi:10.3390/nu13113780 · Cited by 26
Modulating cholesterol-rich lipid rafts to disrupt influenza A virus infection
Li, Y.-J., Chen, C., Yang, J., & Chiu, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.982264 · Cited by 26
Nutrition and Metabolic Correlates of Obesity and Inflammation: Clinical Considerations
Johnson, A. R., & Makowski, L. (2015) · Journal of Nutrition · doi:10.3945/jn.114.200758 · Cited by 26
Interactions between differential fatty acids and inflammatory stressors—impact on metabolic health
Murphy, A. M., Lyons, C. L., Finucane, O. M., & Roche, H. M. (2014) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2014.05.003 · Cited by 26
Kadooka, Y., Ogawa, A., Ikuyama, K., & Sato, M. (2011) · International Dairy Journal · doi:10.1016/j.idairyj.2011.02.001 · Cited by 26
Bouwman, J. J. M., Diepersloot, R. J. A., & Visseren, F. L. J. (2009) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00166-09 · Cited by 26
Chan, P., & Hsieh, P. (2017) · InTech eBooks · doi:10.5772/65458 · Cited by 26
Ursini, F., Mauro, D., Naty, S., Gagliardi, D., & Grembiale, R. D. (2012) · Clinical Rheumatology · doi:10.1007/s10067-012-2034-0 · Cited by 25
Aso, Y., Terasawa, T., Kato, K., Jojima, T., Suzuki, K., Iijima, T., Kawagoe, Y., Mikami, S., Kubota, Y., Inukai, T., et al. (2013) · Translational research · doi:10.1016/j.trsl.2013.07.011 · Cited by 25
Melanin-concentrating hormone and immune function
Lakaye, B., Coumans, B., Harray, S., & Grisar, T. M. (2009) · Peptides · doi:10.1016/j.peptides.2009.05.004 · Cited by 25
Zhao, R., Li, W., Lu, Y., Qin, J., Wu, C., Tian, M., He, T., Yi, S., Tang, D., Sun, L., et al. (2014) · Mediators of Inflammation · doi:10.1155/2014/596967 · Cited by 25
Strodthoff, D., Lundberg, A. M., Agardh, H. E., Ketelhuth, D. F. J., Paulsson‐Berne, G., Arner, P., Hansson, G. K., & Gerdes, N. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.301105 · Cited by 25
Tous, M., Ferrer‐Lorente, R., & Badimón, L. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00059.2014 · Cited by 24
Chemokines and their association with body mass index among healthy Saudis
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Magnuson, A. M., Regan, D. P., Booth, A. D., Fouts, J. K., Solt, C. M., Hill, J. L., Dow, S. W., & Foster, M. T. (2019) · European Journal of Nutrition · doi:10.1007/s00394-019-02019-z · Cited by 24
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Steinhardt, A. P., Tellechea, M. L., Rosso, L. A. G., Brites, F. D., Frechtel, G. D., & Poskus, E. (2011) · BMC Medical Genetics · doi:10.1186/1471-2350-12-166 · Cited by 24
Amadatsu, T., Morinaga, J., Kawano, T., Terada, K., Kadomatsu, T., Miyata, K., Endo, M., Kasamo, D., Kuratsu, J., & Oike, Y. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166285 · Cited by 24
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Marques, S. D. O., Muller, A. P., Luciano, T. F., Tramontin, N. D. S., Caetano, M. D. S., Pieri, B. L. D. S., Amorim, T. L., de Oliveira, M. A. L., & de Souza, C. T. (2022) · Nutrients · doi:10.3390/nu14142906 · Cited by 27
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Hintikka, J. E., Lensu, S., Mäkinen, E., Karvinen, S. M., Honkanen, M., Lindén, J., Garrels, T., Pekkala, S., & Lahti, L. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18084049 · Cited by 21
Graziani, F., Cialdella, P., Liuzzo, G., Basile, E., Brugaletta, S., Pedicino, D., Leccesi, L., Guidone, C., Iaconelli, A., Mingrone, G., et al. (2011) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2011.04.010 · Cited by 22
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Metadata
- Authors
- Kintscher, U., Hartge, M., Hess, K., Foryst-Ludwig, A., Clemenz, M., Wabitsch, M., Fischer-Posovszky, P., Barth, T. F. E., Dragun, D., Skurk, T., Hauner, H., Blüher, M., Unger, T., Wolf, A.-M., Knippschild, U., Hombach, V., & Marx, N.
- Affiliations
- Universität Ulm (DE)
- From the Center for Cardiovascular Research (U.K., M.H., A.F.-L., M.C., T.U.), Institute of Pharmacology, Charité-Universitaetsmedizin, Berlin, Germany; the Department of Internal Medicine II – Cardiology (K.H., V.H., N.M.), University of Ulm, Germany; the Division of Pediatric Endocrinology, Department of Pediatrics and Adolescent Medicine (M.W., P.F.-P.), University of Ulm, Germany; the Department of Pathology (T.F.E.B.), University of Ulm, Germany; the Department of Nephrology, Campus Virchow...
- ORCID
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2008-07
- Volume
- 28
- Issue
- 7
- Pages
- 1304-1310
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2163270865
- Cited by
- 692
- References
- 23
- Citations by year
- 2026: 7 · 2025: 17 · 2024: 21 · 2023: 23 · 2022: 27 · 2021: 34 · 2020: 39 · 2019: 30 · 2018: 34 · 2017: 45 · 2016: 41 · 2015: 41 · 2014: 55 · 2013: 74 · 2012: 52
- FWCI
- 37.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Arteriosclerosis Thrombosis and Vascular Biology (publishedVersion)
- PubMed (publishedVersion)
- mediaTUM (Technical University of Munich) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- T cell infiltration, visceral adipose tissue, adipose tissue inflammation, insulin resistance, obesity, high-fat diet, macrophage recruitment, CD4-positive lymphocytes, HLA-DR, interferon-gamma, type 2 diabetes, waist circumference
- MeSH terms
- Aged, Animals, Cell Movement, Cells, Cultured, Diabetes Mellitus, Type 2, Dietary Fats, Disease Models, Animal, Humans, Insulin Resistance, Interferon-gamma, Macrophages, Male, Mice, Inbred C57BL, Middle Aged, Obesity, Time Factors, Panniculitis, CD4-Positive T-Lymphocytes, Adipocytes, Chemokine CCL2, Body Size, Intra-Abdominal Fat, Mice, Chemokine CXCL12
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