Cardiac Fibrosis: The Fibroblast Awakens

Wound repair and regeneration

Gurtner, G. C., Werner, S., Barrandon, Y., & Longaker, M. T. (2008) · Nature · doi:10.1038/nature07039 · Cited by 6,542

Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association

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Myofibroblasts and mechano-regulation of connective tissue remodelling

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A perivascular origin for mesenchymal stem cells in multiple human organs

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Regulation of type I interferon responses

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A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

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Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors

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TGF-β signaling and the fibrotic response

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

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Cardiac Fibroblasts Play Pathogenic Roles in Idiopathic Restrictive Cardiomyopathy

Tsuru, H., Ishida, H., Narita, J., Ishii, R., Suginobe, H., Ishii, Y., Wang, R., Kogaki, S., Taira, M., Ueno, T., et al. (2021) · Circulation Journal · doi:10.1253/circj.cj-20-1008 · Cited by 11

A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of l -Carnosine

Monroe, T. B., & Anderson, E. J. (2021) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.1c00262 · Cited by 12

Single-cell transcriptome reveals effects of semaglutide on non-cardiomyocytes of obese mice

Pan, X., Chen, X., Ren, Q., Yue, L., Niu, S., Li, Z., Zhu, R., Chen, X., Jia, Z., Zhen, R., et al. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.07.034 · Cited by 11

The complicated lives of GPCRs in cardiac fibroblasts

Mazarura, G. R., Dallagnol, J. C. C., Chatenet, D., Allen, B. G., & Hébert, T. E. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00120.2022 · Cited by 12

Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces cardiac fibroblast proliferation by suppressing GATA Binding Protein 4

Liu, B., Liu, N., Liu, W., Zhang, S., Zhang, J., Li, A., & Liu, S. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.05.095 · Cited by 11

T cells to fix a broken heart

Gao, T. A., & Chen, Y. Y. (2022) · Science · doi:10.1126/science.abn0851 · Cited by 11

From Metabolic Syndrome to Atrial Fibrillation: Linking Inflammatory and Fibrotic Biomarkers with Atrial Remodeling and Imaging-Based Evaluation—A Narrative Review

Merce, A.-G., Nisulescu, D. D., Hermenean, A. O., Burciu, O. M., Munteanu, I.-R., Merce, A.-P., Brie, D. M., & Mornoş, C. (2026) · Metabolites · doi:10.3390/metabo16010059 · Cited by 12

Oncofetal Protein CRIPTO Is Involved in Wound Healing and Fibrogenesis in the Regenerating Liver and Is Associated with the Initial Stages of Cardiac Fibrosis

Karkampouna, S., van der Helm, D., Scarpa, M., van Hoek, B., Verspaget, H. W., Goumans, M., Coenraad, M. J., Kruithof, B. P. T., & Julio, M. K. (2021) · Cells · doi:10.3390/cells10123325 · Cited by 10

Cardiac Reverse Remodeling in Ischemic Heart Disease with Novel Therapies for Heart Failure with Reduced Ejection Fraction

Leancă, S. A., Afrăsânie, I., Crișu, D., Matei, I. T., Duca, Ș.-T., Costache, A. D., Aursulesei, V. O., Tudorancea, I., Mitu, O., Bădescu, M. C., et al. (2023) · Life · doi:10.3390/life13041000 · Cited by 13

Obstructive Sleep Apnea and Hypertensive Heart Disease: From Pathophysiology to Therapeutics

Liu, L., Wang, Y., Hong, L., Bragazzi, N. L., Dai, H., & Chen, H. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2412342 · Cited by 11

AKAP2-anchored extracellular signal-regulated kinase 1 (ERK1) regulates cardiac myofibroblast migration

Delaunay, M., Paterek, A., Gautschi, I., Scherler, G., & Diviani, D. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2024.119674 · Cited by 11

Myocardial fibrosis induced by nonylphenol and its regulatory effect on the TGF-β1/LIMK1 signaling pathway

Guo, M. L., Yu, J., Long, X., Liu, W., Aris, A. Z., Yang, D., Luo, Y., Xu, Y., & Yu, J. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116110 · Cited by 10

The Role of Speckle Tracking Echocardiography in the Evaluation of Advanced-Heart-Failure Patients

Martini, L., Lisi, M., Pastore, M. C., Righini, F. M., Rubboli, A., Henein, M. Y., & Cameli, M. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13144037 · Cited by 10

Taurine and enzymatically modified isoquercitrin protected against methotrexate‐induced deteriorations in the conductivity and rhythmicity of the heart in rats: Antioxidant, anti‐inflammatory, and histological architecture approach

Mahmoud, M. M., El‐Batran, S., Hegazy, R. R., & El-Sayed, W. M. (2024) · Journal of Applied Toxicology · doi:10.1002/jat.4682 · Cited by 10

Circulating collagen type I fragments as specific biomarkers of cardiovascular outcome risk: Where are the opportunities?

Martin, E. M., Chang, J., González, A., & Genovese, F. (2025) · Matrix Biology · doi:10.1016/j.matbio.2025.03.001 · Cited by 9

Downregulation of HSPB1 and MGST1 Promotes Ferroptosis and Impacts Immune Infiltration in Diabetic Cardiomyopathy

Xie, Y., Liang, B., Meng, Z., Guo, R., Liu, C., Yuan, Y., Mu, W., Wang, Y., & Cao, J.-M. (2025) · Cardiovascular Toxicology · doi:10.1007/s12012-025-09982-6 · Cited by 10

Salvia miltiorrhiza Bunge root in the treatment of myocardial fibrosis: research progress and challenges

Li, Q., Ren, C., Jiang, B., Wang, X., Wang, C., Zhi, X., Li, L., Guo, X., Zhao, X., & Li, Y. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1554696 · Cited by 11

Anti-fibrosis effect of astragaloside IV in animal models of cardiovascular diseases and its mechanisms: a systematic review

Zhang, S., Li, S., Li, X., Wan, C., Cui, L., & Wang, Y. (2025) · Pharmaceutical Biology · doi:10.1080/13880209.2025.2488994 · Cited by 10

Pluripotent stem cell-based approaches for heart repair and the potential of genetic modifications

Dulak, J., Zieliński, T., Józkowicz, A., & Łoboda, A. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.07.009 · Cited by 12

EGCG Alleviates Obesity-Induced Myocardial Fibrosis in Rats by Enhancing Expression of SCN5A

Yi, H., Liu, C., Shi, J., Wang, S., Zhang, H., He, Y., Tao, J., Li, S., & Zhang, R. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.869279 · Cited by 10

Sacubitril/valsartan in Heart Failure and Beyond—From Molecular Mechanisms to Clinical Relevance

Muric, M. D., Srejovic, I. M., Joksimović, J., Sretenovic, J. Z., Jeremic, J. N., Čekerevac, I., Simovic, S. M., Djoković, D., Muric, N. N., Stojić, V., et al. (2022) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2307238 · Cited by 11

Fibroblast activation protein: Pivoting cancer/chemotherapeutic insight towards heart failure

Gehris, J., Ervin, C., Hawkins, C., Womack, S. J., Churillo, A. M., Doyle, J., Sinusas, A. J., & Spinale, F. G. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115914 · Cited by 11

Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation

Delgado‐Arija, M., Genovés, P., Pérez-Carrillo, L., González-Torrent, I., Giménez-Escamilla, I., Martínez‐Dolz, L., Portolés, M., Tarazón, E., & Roselló‐Lletí, E. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-04900-w · Cited by 11

CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF‐β1/Smad2/3 signaling in mouse viral myocarditis

Wei, J., Wang, D., Cui, C., Tan, J., Peng, M., & Lu, H. (2024) · Immunity Inflammation and Disease · doi:10.1002/iid3.1237 · Cited by 10

Application of Bioengineered Materials in the Surgical Management of Heart Failure

Pattar, S. S., Hassanabad, A. F., & Fedak, P. W. M. (2019) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2019.00123 · Cited by 10

Tugging at the Heart Strings: The Septin Cytoskeleton in Heart Development and Disease

Moore, K. S., Moore, R. A., Wang, C. E., & Norris, R. A. (2020) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd7010003 · Cited by 10

3,4-Dihydroxybenzalacetone (DBL) Prevents Aging-Induced Myocardial Changes in Senescence-Accelerated Mouse-Prone 8 (SAMP8) Mice

Giridharan, V. V., Karuppagounder, V., Arumugam, S., Nakamura, Y., Guha, A., Barichello, T., Quevedo, J., Watanabe, K., Konishi, T., & Thandavarayan, R. A. (2020) · Cells · doi:10.3390/cells9030597 · Cited by 10

A Large Mammalian Model of Myocardial Regeneration After Myocardial Infarction in Fetal Sheep

Hodges, M. M., Zgheib, C., & Liechty, K. W. (2020) · Advances in Wound Care · doi:10.1089/wound.2018.0894 · Cited by 10

New Insights and Current Approaches in Cardiac Hypertrophy Cell Culture, Tissue Engineering Models, and Novel Pathways Involving Non-Coding RNA

Kastner, N., Zlabinger, K., Spannbauer, A., Traxler, D., Mester-Tonczar, J., Hašimbegović, E., & Gyöngyösi, M. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01314 · Cited by 10

Cannabinoids in Metabolic Syndrome and Cardiac Fibrosis

Navarrete, C. M., García‐Martín, A., DeMesa, J., & Muñóz, E. (2020) · Current Hypertension Reports · doi:10.1007/s11906-020-01112-7 · Cited by 10

Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease

Sullivan, R., Randhawa, V. K., Lalonde, T. J., Yu, T., Kiaii, B. B., Luyt, L. G., Wisenberg, G., & Dhanvantari, S. (2020) · CJC Open · doi:10.1016/j.cjco.2020.10.015 · Cited by 10

Appearance of Heterogeneous Macrophages During Development of Isoproterenol-Induced Rat Myocardial Fibrosis

Koga, M., Karim, M. R., Kuramochi, M., Izawa, T., Kuwamura, M., & Yamate, J. (2021) · Toxicologic Pathology · doi:10.1177/0192623320982526 · Cited by 10

Loss of endothelial cell-specific autophagy-related protein 7 exacerbates doxorubicin-induced cardiotoxicity

Luu, A. Z., Luu, V. Z., Chowdhury, B., Kosmopoulos, A., Pan, Y., Al-Omran, M. A., Quan, A., Teoh, H., Hess, D. A., & Verma, S. (2021) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2021.100926 · Cited by 10

AMPK/Sirt1-mediated inflammation is positively correlated with myocardial fibrosis during ageing

Song, Y., Zhang, Y., Zhang, X., Hu, S., Wang, J., Deng, G., & Zhou, Z. (2022) · Acta cardiologica. Supplementum · doi:10.1080/00015385.2022.2119667 · Cited by 10

Reprint of “The complex dynamics of myocardial interstitial fibrosis in heart failure. Focus on collagen cross-linking”

González, A., López, B., Ravassa, S., José, G. S., & Dı́ez, J. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.07.016 · Cited by 9

Invited Commentary: The Hunt for Mechanistic Origins of Liver Fibrosis in the Fontan Circulation

Rychik, J. R., & Goldmuntz, E. (2021) · World Journal for Pediatric and Congenital Heart Surgery · doi:10.1177/2150135121989974 · Cited by 10

Identification of early cardiac dysfunction and heterogeneity after pressure and volume overload in mice by high-frequency echocardiographic strain imaging

Xu, R., Ding, Z., Li, H., Shi, J., Cheng, L., Xu, H., Wu, J., & Zou, Y. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1071249 · Cited by 9

Myocardial fibrosis in rheumatic heart disease: emerging concepts and clinical implications

Putra, T. M. H., Rodríguez-Fernández, R., Widodo, W. A., Elfiana, M., Laksono, S., Nguyen, Q. N., Tan, J. W. C., & Narula, J. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1230894 · Cited by 9

Association of pulmonary black carbon accumulation with cardiac fibrosis in residents of Sao Paulo, Brazil

Takano, A. P. C., de André, C. D. S., de Almeida, R., Waked, D., Veras, M. M., & Saldiva, P. H. N. (2024) · Environmental Research · doi:10.1016/j.envres.2024.118380 · Cited by 9

Are Endomyocardial Ventricular Biopsies Useful for Assessing Myocardial Fibrosis?

Makarov, I. A., Voronkina, D., Гурщенков, А. В., Рыжков, А. В., Starshinova, A. A., Kudlay, D. A., & Mitrofanova, L. B. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13113275 · Cited by 9

Research progress on programmed cell death of cardiomyocytes in pressure-overload hypertrophic cardiomyopathy

Xiao, F., Li, H., Wang, J., Wu, H., Cai, Y., Wang, J., Che, H., Li, G., Xia, Z., Xie, Y., et al. (2025) · APOPTOSIS · doi:10.1007/s10495-025-02146-5 · Cited by 12

Shenfu injection inhibits myocardial fibrosis by regulating glycolysis through the PI3K-AKT/HIF-1α signaling pathway

Li, X., Li, D., Liu, S., Wang, Y., Fan, X., Yan, Z., Tan, S., Zhuang, P., & Zhang, Y. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.157529 · Cited by 10

Heart failure: mechanistic insights and precision therapeutic strategies

Zhang, F., Zhang, X., Jian, J., Zeng, X., Zheng, C., Zhang, Y., & Gao, J. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1696793 · Cited by 10

State of change: epigenetic and mitochondrial regulation of cardiac fibroblast activation

Garvin, A. M., & Hale, T. M. (2022) · Current Opinion in Physiology · doi:10.1016/j.cophys.2022.100557 · Cited by 9

Inappropriate Activation of TLR4/NF-κB is a Cause of Heart Failure

Zhou, J., Lin, H., Lv, T., Hao, J., Zhang, H., Sun, S., Yang, J., Chi, J., & Guo, H. (2022) · Cardiovascular Innovations and Applications · doi:10.15212/cvia.2022.0020 · Cited by 9

Induction of Senescence by Loss of Gata4 in Cardiac Fibroblasts

Zhang, Z., Shayani, G., Xu, Y., Kim, A., Hong, Y., Feng, H., & Zhu, H. (2023) · Cells · doi:10.3390/cells12121652 · Cited by 10

Transient receptor potential vanilloid type 1: cardioprotective effects in diabetic models

Bao, J., Gao, Z., Hu, Y., Ye, L., & Wang, L. (2023) · Channels · doi:10.1080/19336950.2023.2281743 · Cited by 9

Integrin αV mediated activation of myofibroblast via mechanoparacrine of transforming growth factor β1 in promoting fibrous scar formation after myocardial infarction

Chen, Y.-W., Cheng, P., Yin, Y., Cai, H., Chen, J.-Z., Feng, M., Guo, W., Zhao, P., Zhang, C., Shan, X., et al. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.149360 · Cited by 9

Defining Transcriptomic Heterogeneity between Left and Right Ventricle-Derived Cardiac Fibroblasts

Dewar, M. B., Ehsan, F., Izumi, A., Zhang, H., Zhou, Y., Shah, H., Langburt, D., Suresh, H., Wang, T., Hacker, A., et al. (2024) · Cells · doi:10.3390/cells13040327 · Cited by 11

Mechanical stimulation of induced pluripotent stem cell derived cardiac fibroblasts

Bekedam, F. T., Smal, R., Smit, M. C., Aman, J., Noordegraaf, A. V., Bogaard, H. J., Goumans, M., de Man, F. S., & Valldeperas, A. L. (2024) · Scientific Reports · doi:10.1038/s41598-024-60102-w · Cited by 11

Plumbagin improves myocardial fibrosis after myocardial infarction by inhibiting the AKT/mTOR pathway to upregulate autophagy levels

Guo, S., Qi, X., Zhang, L., Lu, K., Li, X., Zhu, J., & Feng, L. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114086 · Cited by 10

Regulatory effects of resveratrol on nitric oxide signaling in cardiovascular diseases

Abolfazli, S., Karav, S., Johnston, T. P., & Sahebkar, A. (2025) · Pharmacological Reports · doi:10.1007/s43440-025-00694-w · Cited by 9

Sanggenon C protects against pressure overload-induced cardiac hypertrophy via the calcineurin/NFAT2 pathway

Xiao, L., Gu, Y., Gao, L., Shangguan, J., Chen, Y., Zhang, Y., & Li, L. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7288 · Cited by 9

Ski drives an acute increase in MMP-9 gene expression and release in primary cardiac myofibroblasts

Landry, N. M., Kavosh, M., Filomeno, K. L., Rattan, S. G., Czubryt, M. P., & Dixon, I. (2018) · Physiological Reports · doi:10.14814/phy2.13897 · Cited by 9

Genetic variants of HIF1α are associated with right ventricular fibrotic load in repaired tetralogy of Fallot patients: a cardiovascular magnetic resonance study

Hoang, T. T., Manso, P. H., Edman, S., Mercer‐Rosa, L., Mitchell, L. E., Sewda, A., Swartz, M. D., Fogel, M. A., Agopian, A. J., & Goldmuntz, E. (2019) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/s12968-019-0555-2 · Cited by 9

Direct Cardiac Reprogramming for Cardiovascular Regeneration and Differentiation

Sadahiro, T., & Ieda, M. (2020) · The Keio Journal of Medicine · doi:10.2302/kjm.2019-0008-oa · Cited by 9

Cardioprotection by AN-7, a prodrug of the histone deacetylase inhibitor butyric acid: Selective activity in hypoxic cardiomyocytes and cardiofibroblasts

Nudelman, V., Zahalka, M. A., Nudelman, A., Rephaeli, A., & Kessler‐Icekson, G. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173255 · Cited by 9

Losing Regulation of the Extracellular Matrix is Strongly Predictive of Unfavorable Prognostic Outcome after Acute Myocardial Infarction

Sung, P., Lin, K., Chai, H., Chiang, J. Y., Shao, P., Luo, C., & Yip, H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176219 · Cited by 9

LDL‑induced NLRC3 inflammasome activation in cardiac fibroblasts contributes to cardiomyocytic dysfunction

Wang, P., Zhang, W., Feng, Z., Zhang, J., Sun, Y. J., & Zhang, W. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12165 · Cited by 10

Myocardial Cytoskeletal Adaptations in Advanced Kidney Disease

Halim, A., Narayanan, G., Hato, T., Ho, L., Wan, D., Siedlecki, A. M., Rhee, E. P., Allegretti, A. S., Nigwekar, S. U., Zehnder, D., et al. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.121.022991 · Cited by 9

Ultrasonic Microbubble Cavitation Deliver Gal-3 shRNA to Inhibit Myocardial Fibrosis after Myocardial Infarction

Li, W., Jin, Q., Zhang, L., He, S., Song, Y., Xu, L., Deng, C., Wang, L., Qin, X., & Xie, M. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15030729 · Cited by 9

Spleen tyrosine kinase (SYK) signals are implicated in cardio-cerebrovascular diseases

Li, M., Wang, P., Zou, Y., Wang, W., Zhao, Y., Liu, M., Wu, J., Zhang, Y., Zhang, N., & Sun, Y. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e15625 · Cited by 11

Differential Expression of Transforming Growth Factor-β1 Is Associated With Fetal Regeneration After Myocardial Infarction

Hodges, M. M., Zgheib, C., Xu, J., Hu, J., Dewberry, L. C. K., Hilton, S. A., Allukian, M., Gorman, J. H., Gorman, R. C., & Liechty, K. W. (2019) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2018.12.042 · Cited by 9

Short term cyclical stretch phosphorylates p38 and ERK1/2 MAPKs in cultured fibroblasts from the hearts of rainbow trout, Oncorhynchus mykiss

Johnston, E. F., & Gillis, T. E. (2019) · Biology Open · doi:10.1242/bio.049296 · Cited by 9

Epigenetic Regulation of Heart Failure: Cell Type Matters

Padula, S. L., & Yutzey, K. E. (2021) · Circulation Research · doi:10.1161/circresaha.121.319642 · Cited by 9

Trends in worldwide research on cardiac fibrosis over the period 1989–2022: a bibliometric study

Mao, Y., Fu, Q., Feng, S., Zhang, W., Zhong, Z., Zhou, Y., & Yang, C. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1182606 · Cited by 9

The role of TGF-β in cardiac fibrosis and heart failure: A review

Shah, G. B., & Prajapati, A. K. (2024) · IP International Journal of Comprehensive and Advanced Pharmacology · doi:10.18231/j.ijcaap.2024.001 · Cited by 8

Cardiac Metabolism

Martı́n-Puig, S., & Menendez-Montes, I. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-44087-8_19 · Cited by 9

5-Demethylnobiletin Ameliorates Isoproterenol-Induced Cardiac Fibrosis and Apoptosis by Repressing the Sirt1/FOXO3a/NF-κB and Wnt/β-Catenin Pathways

Du, H., Huangfu, W., Liu, Z., Jia, G., Zhao, F., & Cheng, W. (2024) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b24-00122 · Cited by 8

Cell autonomous TLR4 signaling modulates TGF-β induced activation of human cardiac fibroblasts

Vijayakumar, G., Latha, A., Anil, A. P., Surve, Y., Aiswarya, R., Nair, B. G., & Pillai, I. C. L. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e42452 · Cited by 8

Diverse potential of chimeric antigen receptor‐engineered cell therapy: Beyond cancer

Wu, L., Zhu, L., & Chen, J. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70306 · Cited by 9

Diabetic cardiomyopathy: Mechanistic insights on molecular pathways and emerging therapeutic approaches

Kaur, R., Singh, S., Sood, P., Singh, S., Banerjee, S., & Singh, T. G. (2025) · Heart Failure Reviews · doi:10.1007/s10741-025-10562-7 · Cited by 9

Human induced pluripotent stem cell-derived cardiomyocytes for disease modeling and drug discovery

Moriwaki, T., Tani, H., & Tohyama, S. (2025) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2025.1687840 · Cited by 8

Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice

Desai, V. G., Azevedo‐Pouly, A. C. P., Vijay, V., Phanavanh, B., Moland, C. L., Han, T., Revollo, J. R., Aryal, B., Rao, V. A., & Fuscoe, J. C. (2022) · Journal of Applied Toxicology · doi:10.1002/jat.4405 · Cited by 8

Adapted clustering method for generic analysis of histological fibrosis staining as an open source tool

Remes, A. K., Noormalal, M., Schmiedel, N., Frey, N., Frank, D., Müller, O. J., & Graf, M. (2023) · Scientific Reports · doi:10.1038/s41598-023-30196-9 · Cited by 8

Novel polysaccharide identified from Cortinarius purpurascens demonstrated anti-fibrosis effects in cardiac fibroblasts

Niu, P., Tan, X., Zhou, X., Xu, X., Guannan, Z., Li, P., & Bai, M. (2023) · Food Bioscience · doi:10.1016/j.fbio.2023.103157 · Cited by 8

Computational screen for sex-specific drug effects in a cardiac fibroblast signaling network model

Watts, K. M., Nichols, W., & Richardson, W. J. (2023) · Scientific Reports · doi:10.1038/s41598-023-44440-9 · Cited by 8

Astragalus (Astragalus mongholicus) Improves Ventricular Remodeling via ESR1 Downregulation RhoA/ROCK Pathway

Dai, H., Tao, S., Guan, Y., Zhang, Y., Yang, Z., Jia, J., Zhang, X., & Zhang, G. (2023) · International Heart Journal · doi:10.1536/ihj.23-265 · Cited by 8

Synthesis of amide derivatives containing the imidazole moiety and evaluation of their anti‐cardiac fibrosis activity

Yang, Y., Guo, J., Liu, C., Nan, J., Wu, Y., & Jin, C. H. (2024) · Archiv der Pharmazie · doi:10.1002/ardp.202400131 · Cited by 8

Protein Arginine Methyltransferases: Emerging Targets in Cardiovascular and Metabolic Disease

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Pericardial Fluid Accumulates microRNAs That Regulate Heart Fibrosis after Myocardial Infarction

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Aging-associated mechanisms of atrial fibrillation progression and their therapeutic potential

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The m7G methylation modification: An emerging player of cardiovascular diseases

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Therapeutic potential of targeting microRNAs to regulate cardiac fibrosis: miR-433 a new fibrotic player

Ooi, J. Y. Y., Bernardo, B. C., & McMullen, J. R. (2016) · Annals of Translational Medicine · doi:10.21037/atm.2016.12.01 · Cited by 8

AdipoRs- a potential therapeutic target for fibrotic disorders

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Single-cell transcriptional profile of ACE2 in healthy and failing human hearts

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Effects of High-Fat Diet Induced Obesity and Fructooligosaccharide Supplementation on Cardiac Protein Expression

Sarfaraz, S., Singh, S., Hawke, A., Clarke, S. T., & Ramdath, D. D. (2020) · Nutrients · doi:10.3390/nu12113404 · Cited by 8

Actin-granule formation is an additional step in cardiac myofibroblast differentiation

He, L., Liu, R., Yue, H., Ren, S., Zhu, G., Guo, Y., & Qin, C. (2021) · Annals of Translational Medicine · doi:10.21037/atm-20-8231 · Cited by 8

SAHA could inhibit TGF-β1/p38 pathway in MI-induced cardiac fibrosis through DUSP4 overexpression

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Latent‑transforming growth factor β‑binding protein 2 accelerates cardiac fibroblast apoptosis by regulating the expression and activity of caspase‑3

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Rejuvenating the Aging Heart by Enhancing the Expression of the Cisd2 Prolongevity Gene

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A prognostic fibroblast-related risk signature in colorectal cancer

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MircroRNA-145 Attenuates Cardiac Fibrosis Via Regulating Mitogen-Activated Protein Kinase Kinase Kinase 3

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Knockdown of HIPK2 Attenuates Angiotensin II–Induced Cardiac Fibrosis in Cardiac Fibroblasts

Xu, F., Mao, B., Li, Y., & Zhao, Y. (2022) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001292 · Cited by 7

Cardiovascular consequences of sickle cell disease

Palomarez, A., Jha, M., Romero, X. M., & Horton, R. E. (2022) · Biophysics Reviews · doi:10.1063/5.0094650 · Cited by 10

Gβγ subunits colocalize with RNA polymerase II and regulate transcription in cardiac fibroblasts

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Integrated bioinformatics analysis for identifying key genes and pathways in female and male patients with dilated cardiomyopathy

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A bibliometric analysis of cardiomyocyte apoptosis from 2014 to 2023: A review

Wang, R., Luo, X. W., Li, S., Wen, X., Zhang, X., Zhou, Y., & Xie, W. (2023) · Medicine · doi:10.1097/md.0000000000035958 · Cited by 8

Cardiac fibroblasts in myocardial injury and heart failure

Linthout, S. V., Matz, I., González, A., & Davis, J. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf902 · Cited by 38

Cardiac fibrosis: Pathobiology and therapeutic targets

Czubryt, M. P., & Hale, T. M. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.110066 · Cited by 74

Pathophysiology of cardiac fibroblasts and impacts on the severity of the cardiac disease

Duttaroy, A. K., & Mallick, R. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99570-2.00016-3

Characteristics and Regulation of Cardiac Fibroblasts

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The Janus face of myofibroblasts in the remodeling heart

Hermans, K. C. M., Daskalopoulos, E. P., & Blankesteijn, W. M. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.11.017 · Cited by 33