Cited by 821Cardiac electrophysiology and arrhythmiasAcute Myocardial Infarction ResearchCardiac pacing and defibrillation studies

Prevention of Torsade de Pointes in Hospital Settings: A Scientific Statement From the American Heart Association and the American College of Cardiology Foundation

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Drew, Barbara J., Ackerman, Michael J., Funk, Marjorie, Gibler, W. Brian, Kligfield, Paul, Menon, Venu, Philippides, George J., Roden, Dan M. +1 more·2010·Circulation

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Crossref · 10.1161/circulationaha.109.192704

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117 of 117 references verified0 citation errors · 0 not checkable

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  • QTc values > 500 ms have been associated with an increased prevalence of torsades de pointes and other arrhythmias.

    “This is clinically relevant as QTc values > 500 ms have been associated with an increased prevalence of torsades de pointes and other arrhythmias (34).”

    From Effect of Hypoglycemia on QT Interval in Individuals With and Without Type 2 Diabetes: A Randomized Crossover Trial (2025) · cites this paper as [34]

    The “Premonitory ECG Signs of TdP” section states that QTc >500 ms is associated with a two- to threefold higher risk of torsades de pointes in congenital long-QT syndrome studies, with similar increased risk described in drug-induced cases. The copy does not establish that this threshold is associated with increased prevalence of other arrhythmias; the Summary lists other ventricular events as warning signs for torsades, not as outcomes associated with QTc >500 ms. Page numbers were not available in the supplied copy. (LLM, conf=0.88)

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Research works printed but not linked: 1

  1. [1]Dessertenne F La tachycardie ventriculaire á deux foyers opposes variables Arch Mal Coeur Vaiss 1966 59 263 272 4956181

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Authors
Drew, B. J., Ackerman, M. J., Funk, M., Gibler, W. B., Kligfield, P., Menon, V., Philippides, G. J., Roden, D. M., & Zareba, W.
Venue
Circulation
Published
2010-03-02
Volume
121
Issue
8
Pages
1047-1060
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2082072065
Cited by
821
References
115
Citations by year
2026: 32 · 2025: 37 · 2024: 49 · 2023: 41 · 2022: 48 · 2021: 81 · 2020: 90 · 2019: 69 · 2018: 51 · 2017: 62 · 2016: 46 · 2015: 39 · 2014: 43 · 2013: 43 · 2012: 38
FWCI
28.78
Type
journal article
Language
en
Open access
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Heart, Lung, and Blood Institute (R01HL081642)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords
torsades de pointes, ventricular arrhythmia prevention, hospitalized patients, antiarrhythmic drugs, QT prolongation, drug-induced arrhythmia
MeSH terms
Electrocardiography, Heart Rate, Hospital Units, Humans, Monitoring, Physiologic, Risk Factors, United States, Torsades de Pointes

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