Interferon regulatory factor 5 controls necrotic core formation in atherosclerotic lesions by impairing efferocytosis

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.

Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., Abraham, J., Adair, T., Aggarwal, R., Ahn, S. Y., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61728-0 · Cited by 14,070 · see citing works

Macrophage activation and polarization: nomenclature and experimental guidelines

Murray, P. J., Allen, J. E., Biswas, S. K., Fisher, E. A., Gilroy, D. W., Goerdt, S., Gordon, S., Hamilton, J. A., Ivashkiv, L. B., Lawrence, T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.06.008 · Cited by 6,337 · see citing works

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664 · see citing works

From Vulnerable Plaque to Vulnerable Patient

Naghavi, M., Libby, P., Falk, E., Casscells, S. W., Litovsky, S. H., Rumberger, J. A., Badimón, J. J., Stefanadis, C., Moreno, P., Pasterkamp, G., et al. (2003) · Circulation · doi:10.1161/01.cir.0000087481.55887.c9 · Cited by 2,686 · see citing works

Macrophages in the Pathogenesis of Atherosclerosis

Moore, K. J., & Tabas, I. (2011) · Cell · doi:10.1016/j.cell.2011.04.005 · Cited by 2,669 · see citing works

Transcriptional regulation of macrophage polarization: enabling diversity with identity

Lawrence, T., & Natoli, G. (2011) · Nature Reviews Immunology · doi:10.1038/nri3088 · Cited by 2,284 · see citing works

The Immunological Genome Project: networks of gene expression in immune cells

The Immunological Genome Project Consortium, Heng, T. S. P., Painter, M. W., Elpek, K., Lukacs-Kornek, V., Mauermann, N., Turley, S. J., Koller, D., Kim, F. S., Wagers, A. J., et al. (2008) · Nature Immunology · doi:10.1038/ni1008-1091 · Cited by 1,864 · see citing works

Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice

Gu, L., Okada, Y., Clinton, S. K., Gerard, C. J., Sukhova, G. K., Libby, P., & Rollins, B. J. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80139-2 · Cited by 1,574 · see citing works

Identification of a factor that links apoptotic cells to phagocytes

Hanayama, R., Tanaka, M., Miwa, K., Shinohara, A., Iwamatsu, A., & Nagata, S. (2002) · Nature · doi:10.1038/417182a · Cited by 1,401 · see citing works

PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

Bouhlel, M. A., Derudas, B., Rigamonti, E., Dièvart, R., Brozek, J., Haulon, S., Zawadzki, C., Jude, B., Torpier, G., Marx, N., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.06.010 · Cited by 1,325 · see citing works

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

Krausgruber, T., Blazek, K. D., Smallie, T., Alzabin, S., Lockstone, H. E., Sahgal, N., Hussell, T., Feldmann, M., & Udalova, I. A. (2011) · Nature Immunology · doi:10.1038/ni.1990 · Cited by 1,296 · see citing works

Macrophage death and defective inflammation resolution in atherosclerosis

Tabas, I. (2010) · Nature Reviews Immunology · doi:10.1038/nri2675 · Cited by 1,120 · see citing works

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

Takaoka, A., Yanai, H., Kondo, S., Duncan, G. S., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T. W., et al. (2005) · Nature · doi:10.1038/nature03308 · Cited by 1,042 · see citing works

Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress

Cheng, C., Tempel, D., van Haperen, R., van der Baan, A., Grosveld, F. G., Daemen, M. J. A. P., Krams, R., & de Crom, R. (2006) · Circulation · doi:10.1161/circulationaha.105.590018 · Cited by 1,002 · see citing works

Immunobiology of the TAM receptors

Lemke, G., & Rothlin, C. V. (2008) · Nature reviews. Immunology · doi:10.1038/nri2303 · Cited by 867 · see citing works

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

Kojima, Y., Volkmer, J.-P., McKenna, K., Civelek, M., Lusis, A. J., Miller, C. L., Direnzo, D., Nanda, V., Ye, J., Connolly, A. J., et al. (2016) · Nature · doi:10.1038/nature18935 · Cited by 683 · see citing works

Macrophage subsets in atherosclerosis

Chinetti, G., Colin, S., & Staels, B. (2014) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2014.173 · Cited by 640 · see citing works

Macrophage plasticity in experimental atherosclerosis

Khallou-Laschet, J., Varthaman, A., Fornasa, G., Compain, C., Gaston, A.-T., Clement, M., Dussiot, M., Levillain, O., Graff-Dubois, S., Nicoletti, A., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008852 · Cited by 517 · see citing works

Mertk Receptor Mutation Reduces Efferocytosis Efficiency and Promotes Apoptotic Cell Accumulation and Plaque Necrosis in Atherosclerotic Lesions of <i>Apoe</i> ^−/− Mice

Thorp, E., Cui, D., Schrijvers, D. M., Kuriakose, G., & Tabas, I. (2008) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.108.167197 · Cited by 357 · see citing works

Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis

Jongstra‐Bilen, J., Haidari, M., Zhu, S.-N., Chen, M., Guha, D., & Cybulsky, M. I. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060245 · Cited by 328 · see citing works

Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice.

Qiao, J. H., Tripathi, J., Mishra, N. K., Cai, Y., Tripathi, S., Wang, X. P., Imes, S., Fishbein, M. C., Clinton, S. K., Libby, P., et al. (1997) · Europe PMC (PubMed Central) · Cited by 327 · see citing works

Resident Intimal Dendritic Cells Accumulate Lipid and Contribute to the Initiation of Atherosclerosis

Paulson, K. E., Zhu, S.-N., Chen, M., Nurmohamed, S., Jongstra‐Bilen, J., & Cybulsky, M. I. (2009) · Circulation Research · doi:10.1161/circresaha.109.210781 · Cited by 316 · see citing works

In Vivo Silencing of the Transcription Factor IRF5 Reprograms the Macrophage Phenotype and Improves Infarct Healing

Courties, G., Heidt, T., Sebas, M., Iwamoto, Y., Jeon, D., Truelove, J. J., Tricot, B., Wojtkiewicz, G. R., Dutta, P., Sager, H. B., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.11.023 · Cited by 278 · see citing works

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions

Han, S., Liang, C.-P., Seimon, T. A., Ranalletta, M., Welch, C. L., Collins-Fletcher, K., Accili, D., Tabas, I. A., & Tall, A. R. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.02.008 · Cited by 274 · see citing works

Lactadherin Deficiency Leads to Apoptotic Cell Accumulation and Accelerated Atherosclerosis in Mice

Ait-Oufella, H., Kinugawa, K., Zoll, J., Simon, T., Boddaert, J., Heeneman, S., Blanc-Brude, O., Barateau, V., Potteaux, S., Merval, R., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.662080 · Cited by 255 · see citing works

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

Cai, B., Thorp, E. B., Doran, A. C., Subramanian, M., Sansbury, B. E., Lin, C., Spite, M. R., Fredman, G., & Tabas, I. A. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1524292113 · Cited by 253 · see citing works

Functional Role of CD11c + Monocytes in Atherogenesis Associated With Hypercholesterolemia

Wu, H., Gower, R. M., Wang, H., Perrard, X. D., Ma, R., Bullard, D. C., Burns, A. R., Paul, A., Smith, C. W., Simon, S. I., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.823740 · Cited by 232 · see citing works

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

Dalmas, E., Toubal, A., Alzaid, F., Blazek, K., Eames, H. L., Lebozec, K., Pini, M., Hainault, I., Montastier, E., Denis, R. G. P., et al. (2015) · Nature Medicine · doi:10.1038/nm.3829 · Cited by 205 · see citing works

IRF5 controls both acute and chronic inflammation

Weiss, M., Byrne, A. J., Blazek, K. D., Saliba, D. G., Pease, J. E., Perocheau, D. P. B., Feldmann, M., & Udalova, I. A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1506254112 · Cited by 164 · see citing works

Macrophage deficiency of p38α MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice

Seimon, T. A., Wang, Y., Han, S., Senokuchi, T., Schrijvers, D. M., Kuriakose, G., Tall, A. R., & Tabas, I. A. (2009) · Journal of Clinical Investigation · doi:10.1172/jci37262 · Cited by 155 · see citing works

IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages

Saliba, D. G., Heger, A., Eames, H. L., Oikonomopoulos, S., Teixeira, A. S., Blazek, K. D., Androulidaki, A., Wong, D., Goh, F. G., Weiss, M., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.07.034 · Cited by 133 · see citing works

Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4

Fernandez-Boyanapalli, R. F., Frasch, S. C., McPhillips, K. A., Vandivier, R. W., Harry, B. L., Riches, D. W. H., Henson, P. M., & Bratton, D. L. (2008) · Blood · doi:10.1182/blood-2008-05-160564 · Cited by 133 · see citing works

TNF-α Inhibits Macrophage Clearance of Apoptotic Cells via Cytosolic Phospholipase A2 and Oxidant-Dependent Mechanisms

McPhillips, K. A., Janssen, W. J., Ghosh, M., Byrne, A. M., Gardai, S. J., Remigio, L. K., Bratton, D. L., Kang, J. L., & Henson, P. M. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.12.8117 · Cited by 106 · see citing works

CD11c/CD18 Dominates Adhesion of Human Monocytes, Macrophages and Dendritic Cells over CD11b/CD18

Sándor, N., Lukácsi, S., Ungai-Salánki, R., Orgován, N., Szabó, B., Horváth, R., Erdei, A., & Bajtay, Z. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163120 · Cited by 93 · see citing works

Lipopolysaccharide inhibits macrophage phagocytosis of apoptotic neutrophils by regulating the production of tumour necrosis factor α and growth arrest-specific gene 6

Feng, X., Deng, T., Zhang, Y., Su, S., Wei, C., & Han, D. (2010) · Immunology · doi:10.1111/j.1365-2567.2010.03364.x · Cited by 92 · see citing works

Granulocyte Macrophage Colony-Stimulating Factor Regulates Dendritic Cell Content of Atherosclerotic Lesions

Shaposhnik, Z., Wang, X., Weinstein, M. M., Bennett, B. J., & Lusis, A. J. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000254673.55431.e6 · Cited by 87 · see citing works

Spontaneous mutation of the Dock2 gene in Irf5 − / − mice complicates interpretation of type I interferon production and antibody responses

Purtha, W. E., Swiecki, M. K., Colonna, M., Diamond, M. S., & Bhattacharya, D. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1118155109 · Cited by 77 · see citing works

Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques

Seneviratne, A. N., Cole, J. E., Goddard, M. E., Park, I., Mohri, Z., Sansom, S. N., Udalova, I. A., Krams, R., & Monaco, C. G. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.10.034 · Cited by 46 · see citing works

Increased interleukin-1α and interleukin-1β production by macrophages of low-density lipoprotein receptor knock-out mice stimulated with lipopolysaccharide is CD11c/CD18-receptor mediated

Netea, M. G. (1998) · Immunology · doi:10.1046/j.1365-2567.1998.00598.x · Cited by 19 · see citing works

Variants of the Interferon Regulatory Factor 5 Gene Regulate Expression of IRF5 mRNA in Atherosclerotic Tissue But Are Not Associated With Myocardial Infarction

Mälarstig, A., Sigurðsson, S., Eriksson, P. O., Paulsson‐Berne, G., Hedin, U., Wallentin, L. C., Siegbahn, A. G., Hamsten, A., & Syvänen, A.-C. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.163733 · Cited by 14 · see citing works

Macrophages as a therapeutic target to promote diabetic wound healing

Sharifiaghdam, M., Shaabani, E., Majidi, R. F., Smedt, S. C. D., Braeckmans, K., & Fraire, J. C. (2022) · Molecular Therapy · doi:10.1016/j.ymthe.2022.07.016 · Cited by 596 · see citing works

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

Engelen, S. E., Robinson, A., Zurke, Y.-X., & Monaco, C. G. (2022) · Nature Reviews Cardiology · doi:10.1038/s41569-021-00668-4 · Cited by 442 · see citing works

LncRNA MIAT sponges miR-149-5p to inhibit efferocytosis in advanced atherosclerosis through CD47 upregulation

Ye, Z.-M., Yang, S., Xia, Y., Hu, R., Chen, S., Li, B., Chen, S.-L., Luo, X., Mao, L., Li, Y., et al. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1409-4 · Cited by 208 · see citing works

Immune Clearance of Senescent Cells to Combat Ageing and Chronic Diseases

Song, P., An, J., & Zou, M.-H. (2020) · Cells · doi:10.3390/cells9030671 · Cited by 198 · see citing works

The Multiple Roles of Interferon Regulatory Factor family in Health and Disease

Wang, L., Zhu, Y., Zhang, N., Xian, Y., Tang, Y., Ye, J., Reza, F., He, G., Wen, X., & Jiang, X. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01980-4 · Cited by 178 · see citing works

Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity

Cole, J. E., Park, I., Ahern, D., Kassiteridi, C., Danso‐Abeam, D., Goddard, M. E., Green, P. A., Maffia, P., & Monaco, C. G. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy109 · Cited by 172 · see citing works

Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE -/- mice

Ma, C., Xia, R., Yang, S., Liu, L., Zhang, J., Feng, K., Shang, Y., Qu, J., Li, L., Chen, N., et al. (2019) · Theranostics · doi:10.7150/thno.38115 · Cited by 141 · see citing works

Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms

Tajbakhsh, A., Rezaee, M., Kovanen, P. T., & Sahebkar, A. (2018) · Pharmacology &amp; Therapeutics · doi:10.1016/j.pharmthera.2018.02.003 · Cited by 134 · see citing works

Macrophages reprogram after ischemic stroke and promote efferocytosis and inflammation resolution in the mouse brain

Zhang, W., Zhao, J., Wang, R., Jiang, M., Ye, Q., Smith, A. D., Chen, J., & Shi, Y. (2019) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13256 · Cited by 129 · see citing works

Advances and challenges in targeting IRF5, a key regulator of inflammation

Almuttaqi, H., & Udalova, I. A. (2018) · FEBS Journal · doi:10.1111/febs.14654 · Cited by 116 · see citing works

Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture

Sun, J., Singh, P., Shami, A., Kluza, E., Pan, M., Djordjevic, D., Michaelsen, N. B., Kennbäck, C., van der Wel, N. N., Orho‐Melander, M., et al. (2023) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.04.008 · Cited by 114 · see citing works

Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease

Sheng, X., Qiu, C., Liu, H., Gluck, C. A., Hsu, J. Y., He, J., Hsu, C., Sha, D., Weir, M. R., Isakova, T., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2005905117 · Cited by 105 · see citing works

HMGB1–C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis

Liu, T., Xiang, A., Peng, T., Doran, A. C., Tracey, K. J., Barnes, B. J., Tabas, I. A., Son, M., & Diamond, B. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1907490116 · Cited by 93 · see citing works

Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture–prone atherosclerotic plaques

Edsfeldt, A., Swart, M., Singh, P., Dib, L. H., Sun, J., Cole, J. E., Park, I., Al-Sharify, D., Persson, A. F., Nitulescu, M., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehab920 · Cited by 91 · see citing works

IRF5 guides monocytes toward an inflammatory CD11c + macrophage phenotype and promotes intestinal inflammation

Corbin, A., Gomez-Vazquez, M., Berthold, D. L., Attar, M., Arnold, I. C., Powrie, F. M., Sansom, S. N., Udalova, I. A., Sansom, S. N., & Udalova, I. A. (2020) · Science Immunology · doi:10.1126/sciimmunol.aax6085 · Cited by 85 · see citing works

NOX2 inhibition stabilizes vulnerable plaques by enhancing macrophage efferocytosis via MertK/PI3K/AKT pathway

Wang, Y., Liu, X.-Y., Wang, Y., Zhao, W.-X., Li, F.-D., Guo, P.-R., Fan, Q., & Wu, X.-F. (2023) · Redox Biology · doi:10.1016/j.redox.2023.102763 · Cited by 81 · see citing works

Targeting senescent cells to attenuate cardiovascular disease progression

Song, P., Zhao, Q., & Zou, M. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101072 · Cited by 76 · see citing works

Exosomal CagA derived from Helicobacter pylori-infected gastric epithelial cells induces macrophage foam cell formation and promotes atherosclerosis

Yang, S., Xia, Y., Luo, X., Chen, S., Li, B., Ye, Z.-M., Chen, S., Mao, L., Jin, H., Li, Y., et al. (2019) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2019.07.011 · Cited by 75 · see citing works

Signals governing monocyte differentiation during inflammation

Orozco, S. L., Canny, S., & Hamerman, J. A. (2021) · Current Opinion in Immunology · doi:10.1016/j.coi.2021.07.007 · Cited by 69 · see citing works

RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism

Senatus, L. M., López‐Díez, R., Egaña-Gorroño, L., Liu, J., Hu, J., Daffu, G. K., Li, Q., Rahman, K., Vengrenyuk, Y., Barrett, T. J., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.137289 · Cited by 68 · see citing works

Potential Mechanisms and Effects of Efferocytosis in Atherosclerosis

Wang, L., Li, H., Tang, Y., & Yao, P. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.585285 · Cited by 62 · see citing works

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

Park, I., Goddard, M. E., Cole, J. E., Zanin, N., Lyytikäinen, L., Lehtimäki, T. J., Andreakos, E., Feldmann, M., Udalova, I. A., Drozdov, I. A., et al. (2022) · Nature Communications · doi:10.1038/s41467-021-27862-9 · Cited by 61 · see citing works

Therapeutic Targeting of IRFs: Pathway-Dependence or Structure-Based?

Thompson, C. D., Matta, B., & Barnes, B. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02622 · Cited by 56 · see citing works

A Galectin-9–Driven CD11c high Decidual Macrophage Subset Suppresses Uterine Vascular Remodeling in Preeclampsia

Li, Y., Sang, Y., Chang, Y., Xu, C., Lin, Y., Zhang, Y., Chiu, P. C. N., Yeung, W. S. B., Zhou, H., Dong, N., et al. (2024) · Circulation · doi:10.1161/circulationaha.123.064391 · Cited by 60 · see citing works

Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization

Wei, J., Tang, D., Lu, C., Yang, J., Lu, Y., Wang, Y., Jia, L., Wang, J., Ru, W., Lü, Y., et al. (2019) · Mucosal Immunology · doi:10.1038/s41385-019-0169-x · Cited by 54 · see citing works

Pathophysiology of Atherosclerotic Plaque Development-Contemporary Experience and New Directions in Research

Kowara, M., & Cudnoch‐Jędrzejewska, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073513 · Cited by 54 · see citing works

Metabolic and Molecular Mechanisms of Macrophage Polarisation and Adipose Tissue Insulin Resistance

Orliaguet, L., Ejlalmanesh, T., & Alzaïd, F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165731 · Cited by 50 · see citing works

Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management

Dong, X., Suo, Y., Yu, J. Z., Yu, F., Feng, L., Zheng, J., Li, G., Ma, S., Hao, Y., Zhang, H., et al. (2025) · ACS Nano · doi:10.1021/acsnano.5c00216 · Cited by 50 · see citing works

Molecular mechanisms and genetic regulation in atherosclerosis

Jackson, A. O., Regine, M. A., Chakrabarti, S., & Long, S. (2018) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2018.09.006 · Cited by 49 · see citing works

Macrophage ALDH2 (Aldehyde Dehydrogenase 2) Stabilizing Rac2 Is Required for Efferocytosis Internalization and Reduction of Atherosclerosis Development

Zhang, J., Zhao, X., Guo, Y., Liu, Z., Wei, S., Yuan, Q., Shang, H., Sang, W., Cui, S., Xu, T., et al. (2022) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.121.317204 · Cited by 49 · see citing works

IRF5-mediated immune responses and its implications in immunological disorders

Kaur, A., Lee, L., Chow, S.-C., & Fang, C.-M. (2018) · International Reviews of Immunology · doi:10.1080/08830185.2018.1469629 · Cited by 41 · see citing works

Astragalus Flavone Ameliorates Atherosclerosis and Hepatic Steatosis Via Inhibiting Lipid-Disorder and Inflammation in apoE−/− Mice

Ma, C.-R., Zhang, J., Yang, S., Hua, Y., Su, J., Shang, Y., Wang, Z.-Y., Feng, K., Zhang, J., Yang, X.-X., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.610550 · Cited by 41 · see citing works

IGFBP6 Is Downregulated in Unstable Carotid Atherosclerotic Plaques According to an Integrated Bioinformatics Analysis and Experimental Verification

Liu, Y., Huan, W., Wu, J., Zou, S., & Qu, L. (2020) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.52993 · Cited by 40 · see citing works

Dead cell and debris clearance in the atherosclerotic plaque: Mechanisms and therapeutic opportunities to promote inflammation resolution

Dhawan, U. K., Singhal, A., & Subramanian, M. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105699 · Cited by 40 · see citing works

CD200 Limits Monopoiesis and Monocyte Recruitment in Atherosclerosis

Kassiteridi, C., Cole, J. E., Griseri, T., Falck-Hansen, M., Goddard, M. E., Seneviratne, A. N., Green, P. A., Park, I., Shami, A., Pattarabanjird, T., et al. (2021) · Circulation Research · doi:10.1161/circresaha.119.316062 · Cited by 37 · see citing works

Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation

Ryzhakov, G., Almuttaqi, H., Corbin, A., Berthold, D. L., Khoyratty, T. E., Eames, H. L., Bullers, S. J., Pearson, C. F., Ai, Z., Zec, K., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-27038-5 · Cited by 37 · see citing works

Diverse mechanisms of IRF5 action in inflammatory responses.

Khoyratty, T. E., & Udalova, I. (2018) · International Journal of Biochemistry and Cell Biology · doi:10.1016/j.biocel.2018.03.012 · Cited by 34 · see citing works

Architecture‐Engineered Electrospinning Cascade Regulates Spinal Microenvironment to Promote Nerve Regeneration

Tang, Y., Xu, Z., Tang, J., Xu, Y., Li, Z., Wang, W., Wu, L., Xi, K., Gu, Y., & Chen, L. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202202658 · Cited by 33 · see citing works

Macrophage autophagy regulates mitochondria‐mediated apoptosis and inhibits necrotic core formation in vulnerable plaques

Xiao, Q., Che, X., Cai, B., Tao, Z., Zhang, H., Shao, Q., & Pu, J. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14715 · Cited by 33 · see citing works

Guanxinkang Decoction Attenuates the Inflammation in Atherosclerosis by Regulating Efferocytosis and MAPKs Signaling Pathway in LDLR−/− Mice and RAW264.7 Cells

Zhang, Y., Ding, J., Wang, Y., Feng, X., Du, M., & Liu, P. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.731769 · Cited by 33 · see citing works

Macrophage reprogramming into a pro-healing phenotype by siRNA delivered with LBL assembled nanocomplexes for wound healing applications

Sharifiaghdam, M., Shaabani, E., Sharifiaghdam, Z., Keersmaecker, H. D., Lucas, B., Lammens, J., Ghanbari, H., Teimoori‐Toolabi, L., Vervaet, C., Beer, T. D., et al. (2021) · Nanoscale · doi:10.1039/d1nr03830c · Cited by 32 · see citing works

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice

Leipner, J., Dederichs, T.-S., von Ehr, A., Rauterberg, S., Ehlert, C. A., Merz, J., Dufner, B., Hoppe, N., Krebs, K., Heidt, T., et al. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101250 · Cited by 31 · see citing works

Resolvin T4 enhances macrophage cholesterol efflux to reduce vascular disease

Walker, M. E., Matteis, R. D., Perretti, M., & Dalli, J. (2024) · Nature Communications · doi:10.1038/s41467-024-44868-1 · Cited by 30 · see citing works

eNOS-Nitric Oxide System Contributes to a Novel Antiatherogenic Effect of Leonurine via Inflammation Inhibition and Plaque Stabilization

Ning, K., Wang, M.-J., Ge, L., Zhang, Y., Li, M.-Y., Yang, B., Chen, Y., Huang, Y., Li, Z., Huang, Y., et al. (2020) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.119.264887 · Cited by 29 · see citing works

Mechanism of Efferocytosis in Determining Ischaemic Stroke Resolution—Diving into Microglia/Macrophage Functions and Therapeutic Modality

Xie, X.-D., Dong, S., Liu, R., Shi, L., & Zhu, T. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04060-4 · Cited by 28 · see citing works

Inflammatory Macrophage-Targeted Atherosclerosis Treatment by miRNA-Delivered, MRI-Visible, and Anti-Inflammatory Nanomedicine

Li, X., Chen, Y., Cao, X., Feng, W., Chen, Y., & Zhang, J. (2025) · ACS Nano · doi:10.1021/acsnano.4c16585 · Cited by 28 · see citing works

Research progress on the active ingredients of traditional Chinese medicine in the intervention of atherosclerosis: A promising natural immunotherapeutic adjuvant

Jing, J., Zhu, C., Gong, R., Qi, X., Zhang, Y., & Zhang, Z. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114201 · Cited by 26 · see citing works

New Concepts on the Pathophysiology of Acute Coronary Syndrome

Yuan, D., Chu, J., Qian, J., Lin, H., Zhu, G., Chen, F., & Liu, X. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2404112 · Cited by 26 · see citing works

IRF5 siRNA Nanoimmunotherapy: Restoring Macrophage Efferocytosis in Atherosclerosis

He, Z., Luo, Y., Duan, Z., Su, B., Zeng, W., Guo, Y., Li, Y., He, X., Shi, H., Zhou, Z., et al. (2025) · Circulation · doi:10.1161/circulationaha.125.075352 · Cited by 24 · see citing works

Macrophages in Atheromatous Plaque Developmental Stages

von Ehr, A., Bode, C., & Hilgendorf, I. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.865367 · Cited by 23 · see citing works

Ca2+ Flux: Searching for a Role in Efferocytosis of Apoptotic Cells in Atherosclerosis

Tajbakhsh, A., Kovanen, P. T., Rezaee, M., Banach, M., & Sahebkar, A. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8122047 · Cited by 24 · see citing works

Defining the Role of Monocytes in Sjögren’s Syndrome

Sequí-Sabater, J. M., & Beretta, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112765 · Cited by 23 · see citing works

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Bai, Q., Lao, X., Pang, S., Zhao, Y., Liu, Y., Tian, X. Y., & Hao, J. (2025) · Advanced Materials · doi:10.1002/adma.202420189 · Cited by 21 · see citing works

Recent advances in dead cell clearance during acute lung injury and repair

Noone, P. M., & Reddy, S. P. (2021) · Faculty Reviews · doi:10.12703/r/10-33 · Cited by 21 · see citing works

Synergistic inflammatory signaling by cGAS may be involved in the development of atherosclerosis

Lu, G., Chen, S.-C., Xia, Y., Ye, Z.-M., Cao, F., & Hu, B. (2021) · Aging · doi:10.18632/aging.202491 · Cited by 20 · see citing works

Protective Functions of Liver X Receptor α in Established Vulnerable Plaques: Involvement of Regulating Endoplasmic Reticulum–Mediated Macrophage Apoptosis and Efferocytosis

Che, X., Xiao, Q., Song, W., Zhang, H., Sun, B., Geng, N., Tao, Z., Shao, Q., & Pu, J. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.018455 · Cited by 20 · see citing works

Interferon regulatory factor 5: a potential target for therapeutic intervention in inflammatory diseases

Yu, X., Rehman, A. U., Dang, L., Zhang, X., Liu, J., Xiong, X., Chen, G., & Jian, Z. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1535823 · Cited by 19 · see citing works

Integrating Bulk RNA and Single-Cell Sequencing Data Unveils Efferocytosis Patterns and ceRNA Network in Ischemic Stroke

Yuan, J., Liao, Y.-S., Zhang, T.-C., Tang, Y.-Q., Yu, P., Liu, Y., Cai, D., Yu, S., & Zhao, L. (2024) · Translational Stroke Research · doi:10.1007/s12975-024-01255-8 · Cited by 20 · see citing works

Functional diversity of macrophages in vascular biology and disease.

Park, I., Kassiteridi, C., & Monaco, C. (2017) · Vascular pharmacology · doi:10.1016/j.vph.2017.10.005 · Cited by 18 · see citing works

Activation of CD137 signaling promotes macrophage apoptosis dependent on p38 MAPK pathway-mediated mitochondrial fission

Xu, Y., Zhang, Y., Xu, Y., Zang, G., Li, B., Xia, H., & Yuan, W. (2021) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2021.106003 · Cited by 19 · see citing works

Air pollution and atherosclerosis

Seneviratne, A. N., & Miller, M. R. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.119240 · Cited by 19 · see citing works

IRF5 governs macrophage adventitial infiltration to fuel abdominal aortic aneurysm formation

Wang, Y., Liu, Z., Song, S., Wang, J., Jin, C., Jia, L., Ma, Y., Yuan, T., Cai, Z., & Xiang, M. (2024) · JCI Insight · doi:10.1172/jci.insight.171488 · Cited by 18 · see citing works

Arsenic trioxide alleviates atherosclerosis by inhibiting CD36-induced endocytosis and TLR4/NF-κB-induced inflammation in macrophage and ApoE-/- mice

Li, Z., Zou, X., Lu, R., Wan, X., Sun, S., Wang, S., Qu, Y., Zhang, Y., Li, Z., Yang, L. M., et al. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111452 · Cited by 18 · see citing works

Defective efferocytosis of vascular cells in heart disease

Singh, B., Li, K. S., Cui, K., Peng, Q., Cowan, D. B., Wang, D., Chen, K., & Chen, H. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1031293 · Cited by 16 · see citing works

Spatiotemporal Gene Coexpression and Regulation in Mouse Cardiomyocytes of Early Cardiac Morphogenesis

Liu, Y., Lu, P., Wang, Y., Morrow, B. E., Zhou, B., & Zheng, D. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.012941 · Cited by 15 · see citing works

Insights on TAM Formation from a Boolean Model of Macrophage Polarization Based on In Vitro Studies

Marku, M., Verstraete, N., Raynal, F., Madrid-Mencía, M., Domagala, M., Fournié, J., Ysebaert, L., Poupot, M., & Pancaldi, V. (2020) · Cancers · doi:10.3390/cancers12123664 · Cited by 16 · see citing works

Sonodynamic Therapy Promotes Efferocytosis via CD47 Down-Regulation in Advanced Atherosclerotic Plaque

Cao, Y., Yao, J., Gao, W., Cao, Z., Diabakte, K., Wang, L., Sun, X., & Tian, Y. (2022) · International Heart Journal · doi:10.1536/ihj.21-233 · Cited by 15 · see citing works

Identification of ITGAX and CCR1 as potential biomarkers of atherosclerosis via Gene Set Enrichment Analysis

Yan, S., Meng, L., Guo, X., Chen, Z., Zhang, Y.-M., & Li, Y. (2022) · Journal of International Medical Research · doi:10.1177/03000605211039480 · Cited by 13 · see citing works

Interplay Between KLF4, STAT, IRF, and NF-κB in VSMC and Macrophage Plasticity During Vascular Inflammation and Atherosclerosis

Łopacinska, N., Wesoły, J., & Bluyssen, H. A. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262010205 · Cited by 14 · see citing works

MicroRNA-22 inhibition promotes the development of atherosclerosis via targeting interferon regulator factor 5

Wu, Z., Geng, J., Bai, Y., Qi, Y., Chang, C. C., Jiao, Y., & Guo, Z. (2021) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112922 · Cited by 12 · see citing works

The macrophage-derived motor protein KIF13B enhances MERTK-mediated efferocytosis and prevents atherosclerosis in mice

Xu, Y., Chen, J., Liu, Y., Zhang, G., Miao, G., Wu, J., Lu, K., Zhao, Y., Zhang, W., Zheng, L., et al. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf523 · Cited by 11 · see citing works

Identification of pathways and key genes in male late‑stage carotid atherosclerosis using bioinformatics analysis

Zhang, D., Li, X., Jing, B., Shi, H., Chang, S., Chen, Z., Zheng, Y., Pan, Y., Qian, G., & Zhao, G. (2022) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2022.11387 · Cited by 10 · see citing works

MAT2A promotes atherosclerotic plaque vulnerability by mediating epigenetic reprogramming of macrophages

Du, Z., Wan, P., Du, M., Li, S., Yan, Q., Sun, S., Tang, C., Jiang, Z., Li, S., Shi, G., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-66121-z · Cited by 8 · see citing works

More Than a Cleanup Crew: The Expanding Biology of Efferocytosis

Pandit, R., Hillman, H., Williams, J. W., & Yurdagul, A. (2025) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.125.323211 · Cited by 7 · see citing works

Expression of ectopic trypsin in atherosclerotic plaques and the effects of aprotinin on plaque stability

Shi, J., Pan, H., Liu, K., Pan, M., & Si, G.-J. (2020) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108460 · Cited by 8 · see citing works

Identification of ALEKSIN as a novel multi-IRF inhibitor of IRF- and STAT-mediated transcription in vascular inflammation and atherosclerosis

Antonczyk, A., Kluzek, K., Herbich, N., Boroujeni, M. E., Krist, B., Wronka, D., Karlik, A., Przybył, Ł., Plewiński, A., Wesoły, J., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1471182 · Cited by 7 · see citing works

Haemodynamic Effects on the Development and Stability of Atherosclerotic Plaques in Arterial Blood Vessel

Lei, W., Qian, S., Zhu, X., & Hu, J. (2023) · Interdisciplinary Sciences Computational Life Sciences · doi:10.1007/s12539-023-00576-w · Cited by 7 · see citing works

Emerging areas for therapeutic discovery in SLE

Maria, N. I., & Davidson, A. (2018) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.09.004 · Cited by 7 · see citing works

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Huang, Z., Shen, S., Li, W., Wang, M., Yu, Y., Luo, W., Han, X., Xu, Z., Min, J., Long, X., et al. (2025) · Advanced Science · doi:10.1002/advs.202503192 · Cited by 7 · see citing works

IRF5 Mediates Artery Inflammation in Salt-Sensitive Hypertension by Regulating STAT1 and STAT2 Phosphorylation to Increase ESM1 Transcription: Insights from Bioinformatics and Mechanistic Analysis

Shao, Q., Wang, H., Li, S., Zeng, M., Zhang, S., & Yan, X. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083722 · Cited by 6 · see citing works

Environmental modulators of vascular physiology and inflammation

Seneviratne, A. N., Majumdar, A., Surendranath, K., & Miller, M. R. (2025) · Experimental Physiology · doi:10.1113/ep092309 · Cited by 5 · see citing works

The role of interferon regulatory factors in atherosclerosis: from cell type-specific mechanisms to therapeutic strategies

Huang, J., Wang, J., Chen, H. H., Guo, F., & Yuan, X. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1795987 · Cited by 5 · see citing works

Correlative analysis of transcriptome and proteome in Penaeus vannamei reveals key signaling pathways are involved in IFN-like antiviral regulation mediated by interferon regulatory factor (PvIRF)

Liu, Y., He, Y., Cao, J., Lu, H., Zou, R., Zuo, Z., Li, R., Zhang, Y., & Sun, J. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.127138 · Cited by 5 · see citing works

IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice

Mai, L. T., Smans, M., Silva‐Barrios, S., Fabié, A., & Stäger, S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03071 · Cited by 5 · see citing works

Interferon Regulatory Factor 5 (IRF5) Gene Haplotypes Are Associated with Premature Coronary Artery Disease. Association of the IRF5 Polymorphisms with Cardiometabolic Parameters. The Genetics of Atherosclerotic Disease (GEA) Mexican Study

Posadas‐Sánchez, R., Cardoso-Saldaña, G. C., Fragoso, J. M., & Vargas‐Alarcón, G. (2021) · Biomolecules · doi:10.3390/biom11030443 · Cited by 5 · see citing works

The role of interferon regulatory factors in atherosclerosis

Wang, Y., Fang, T., Zheng, X., & Huangfu, N. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1606034 · Cited by 4 · see citing works

The Role of Ubiquitination on Macrophages in Cardiovascular Diseases and Targeted Treatment

Wang, L., Zhang, Y., Yue, J., & Zhou, R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26094260 · Cited by 4 · see citing works

Periaortic lymphatic vessels protect against thoracic aortic dissection through mobilizing immune response

Pei, Y., Lin, W., Zhang, T., Chu, X., Xu, H., Sun, Y., Xu, M., Xu, Y., Huang, F., Huang, D., et al. (2025) · Cardiovascular Research · doi:10.1093/cvr/cvaf215 · Cited by 3 · see citing works

The role of integrin-related genes in atherosclerosis complicated by abdominal aortic aneurysm

Hong, D., Ma, L., Jin, L., Tang, L., Chen, L., & Qiu, Z. (2024) · Medicine · doi:10.1097/md.0000000000040293 · Cited by 3 · see citing works

LncRNA SCARNA8 promotes atherosclerotic plaque instability by inhibiting macrophage efferocytosis

Yin, X., Chen, X., Wang, T., Yang, J., Yu, J., & Yang, J. (2025) · Epigenetics · doi:10.1080/15592294.2025.2487317 · Cited by 3 · see citing works

Targeted restoration of macrophage mitochondrial function by astaxanthin-geniposide co-assembled nanosystem for atherosclerosis treatment

Luo, X., Zhao, C., Yu, F., Dong, X., Hao, Y., Zhang, H., Liu, B., & Jiang, Y. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.176037 · Cited by 2 · see citing works

Disruption of the novel nested gene Aff3ir mediates disturbed flow-induced atherosclerosis in mice

He, S., Huang, L., Chen, Z., Yuan, Z., Zhao, Y., Zeng, L., Zhu, Y., & He, J. (2025) · eLife · doi:10.7554/elife.103413.3 · Cited by 2 · see citing works

Unravelling immune cell complexity in atherosclerosis

Clément, M., & Mallat, Z. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy165 · Cited by 2 · see citing works

IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards a pathogenic CD11c + macrophage phenotypePreprint

Corbin, A., Gomez-Vazquez, M., Khoyratty, T. E., Berthold, D. L., Almuttaqi, H., Attar, M., Arnold, I. C., Powrie, F. M., Sansom, S. N., & Udalova, I. A. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/601963 · Cited by 2 · see citing works

Advancing therapeutic targeting of the vulnerable plaque

Newman, A. A. C., Cyr, Y., & Moore, K. J. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac060 · Cited by 2 · see citing works

Gut Microbiota-Derived Leucine Promotes Cold-Induced Atherosclerosis by Inhibiting Macrophage EfferocytosisPreprint

Gong, Y., Yan, S. R., Fang, N., Zhang, Y., Zhang, N., Li, L., Wang, Z., Wang, K., Hou, T., Ji, X., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4666347/v1 · Cited by 2 · see citing works

Mechanisms of aging in the cardiovascular system: challenges and opportunities

Zhao, X., Yang, X., Lin, Y., Lei, R., Ding, W., He, X.-Y., Cao, Y. J., Zhang, D., Liu, P., Liang, M., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1635736 · Cited by 4 · see citing works

PYK2 controls intestinal inflammation via activation of IRF5 in macrophagesPreprint

Ryzhakov, G., Almuttaqi, H., Corbin, A., Khoyratty, T. E., Berthold, D. L., Bullers, S. J., Eames, H. L., Ai, Z., Bonham, S., Fischer, R., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.24.113076 · Cited by 1 · see citing works

Arsenic Trioxide Ameliorates Atherosclerosis by Inhibiting CD36-Induced Endocytosis and Tlr4/Nf-Κb-Induced Inflammation in Macrophage and Apoe-/- MicePreprint

Zou, X., Li, Z., WAN, X., Sun, S., Wang, S., Qu, N., Zhang, Y., Lu, R., Li, Z., Yang, L. M., et al. (2022) · SSRN Electronic Journal · doi:10.22541/au.170669100.03220590/v1 · Cited by 1 · see citing works

Disruption of the novel nested gene Aff3ir mediates disturbed flow-induced atherosclerosis in micePreprint

He, S., Huang, L., Chen, Z., Yuan, Z., Zhao, Y., Zeng, L., Zhu, Y., & He, J. (2024) · eLife · doi:10.7554/elife.103413 · Cited by 1 · see citing works

Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture–prone atherosclerotic plaques

Edsfeldt, A., Swart, M., Singh, P., Dib, L. H., Sun, J., Cole, J. E., Park, I., Al-Sharify, D., Persson, A. F., Nitulescu, M., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehab920 · Cited by 91 · see citing works

Shear stress and interferon regulatory gactor 5 modulate myeloid cell behaviour in atherosclerosis

Seneviratne, A. N. (2014) · doi:10.25560/45408 · Cited by 1 · see citing works

Macrophage-specific IRF5 deficiency stabilizes atherosclerotic plaques in ApoE−/− mice

Hilgendorf, I., Haerdtner, C., Leipner, J., Dufner, B., Hoppe, N., Wolf, D., Stachon, P., Zirlik, A., & Bode, C. (2020) · European Heart Journal · doi:10.1093/ehjci/ehaa946.3748 · Cited by 2 · see citing works

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice

Leipner, J., Dederichs, T.-S., von Ehr, A., Rauterberg, S., Ehlert, C. A., Merz, J., Dufner, B., Hoppe, N., Krebs, K., Heidt, T., et al. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101250 · Cited by 31 · see citing works

Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice

Döring, Y., Soehnlein, O., Drechsler, M. D., Shagdarsuren, E., Chaudhari, S. M., Meiler, S. U., Hartwig, H., Hristov, M., Koenen, R. R., Hieronymus, T., et al. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.236539 · Cited by 48 · see citing works