Cited by 52Sodium Intake and HealthBlood Pressure and Hypertension StudiesElectrolyte and hormonal disorders

National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness: Building on the Current Scientific Evidence

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Oh, Young S., Appel, Lawrence J., Galis, Zorina S., Hafler, David A., He, Jiang, Hernandez, Amanda L., Joe, Bina, Karumanchi, S. Ananth +10 more·2016·Hypertension

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Crossref · 10.1161/hypertensionaha.116.07415

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  • The mechanisms of salt sensitivity of blood pressure are complex and likely involve responses beyond excess volume retention, including vascular dysfunction, arterial stiffness, sympathetic activation, impaired renin-angiotensin axis suppression, mineralocorticoid receptor activation, and immune cell modulation.

    “The mechanisms are complex and likely involve a host of responses beyond excess volume retention, including vascular dysfunction, arterial stiffness, sympathetic activation, impaired renin-angiotensin axis suppression, mineralocorticoid receptor activation, and immune cell modulation.156,157”

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Authors
Oh, Y. S., Appel, L. J., Galis, Z. S., Hafler, D. A., He, J., Hernandez, A. L., Joe, B., Karumanchi, S. A., Maric-Bilkan, C., Mattson, D., Mehta, N. N., Randolph, G., Ryan, M., Sandberg, K., Titze, J., Tolunay, E., Toney, G. M., & Harrison, D. G.
Affiliations
  • Tulane University (US)
  • From the Division of Cardiovascular Sciences (Y.S.O, Z.S.G., C.M.-B., E.T.) and Division of Intramural Research (N.N.M.), National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD; Department of Medicine, Johns Hopkins University, Baltimore, MD (L.J.A.); Department of Neurology and Department of Immunobiology, Yale University School of Medicine, New Haven, CT (A.L.H., D.A.H.); Department of Epidemiology, Tulane University, New Orleans, LA (J.H.); Department of Physiology...
Corresponding author
Oh, Young S.
Venue
Hypertension
Published
2016-08
Volume
68
Issue
2
Pages
281-288
ISSN
  • 0194-911X (ISSN-L)
  • 1524-4563
OpenAlex
W2466915263
Cited by
52
References
69
Citations by year
2026: 1 · 2025: 2 · 2024: 3 · 2023: 4 · 2021: 4 · 2020: 9 · 2019: 5 · 2018: 10 · 2017: 12 · 2016: 2
FWCI
1.19
Type
journal article
Language
en
Open access
Locations
  • Hypertension (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (5r01hl119380-04, Z99 HL999999, UL1TR001863)
  • National Heart, Lung, and Blood Institute (R01HL020176, R01 HL-119380)
  • National Institute of General Medical Sciences (T32GM007205)
  • National Institute of Diabetes and Digestive and Kidney Diseases (P30DK072488)
  • National Center for Advancing Translational Sciences
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
Keywords
dietary salt, sodium intake, cardiovascular disease, salt reduction, human health, disease risk
MeSH terms
Humans, United States, Sodium Chloride, Dietary, National Heart, Lung, and Blood Institute (U.S.)

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