Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 266

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Life’s Simple 7 and Risk of Incident Stroke: The Reasons for Geographic and Racial Differences in Stroke Study

Open access
Kulshreshtha, Ambar, Vaccarino, Viola, Judd, Suzanne E., Howard, Virginia J., McClellan, William M., Muntner, Paul, Hong, Yuling, Safford, Monika M., Goyal, Abhinav, Cushman, Mary·2013·Stroke

Abstract

Background and Purpose—: The American Heart Association developed Life’s Simple 7 (LS7) as a metric defining cardiovascular health. We investigated the association between LS7 and incident stroke in black and white Americans. Methods—: The Reasons for Geographic And Racial Differences in Stroke (REGARDS) is a national population-based cohort of 30 239 blacks and whites, aged ≥45 years, sampled from the US population from 2003 to 2007. Data were collected by telephone, self-administered questionnaires, and an in-home examination. Incident strokes were identified through biannual participant contact followed by adjudication of medical records. Levels of the LS7 components (blood pressure, cholesterol, glucose, body mass index, smoking, physical activity, and diet) were each coded as poor (0 point), intermediate (1 point), or ideal (2 points) health. An overall LS7 score was categorized as inadequate (0–4), average (5–9), or optimum (10–14) cardiovascular health. Results—: Among 22 914 subjects with LS7 data and no previous cardiovascular disease, there were 432 incident strokes over 4.9 years of follow-up. After adjusting for demographics, socioeconomic status, and region of residence, each better health category of the LS7 score was associated with a 25% lower risk of stroke (hazard ratios, 0.75; 95% confidence interval, 0.63–0.90). The association was similar for blacks and whites (interaction P value=0.55). A 1-point higher LS7 score was associated with an 8% lower risk of stroke (hazard ratios, 0.92; 95% confidence interval, 0.88–0.95). Conclusions—: In both blacks and whites, better cardiovascular health, on the basis of the LS7 score, is associated with lower risk of stroke, and a small difference in scores was an important stroke determinant.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1161/strokeaha.111.000352

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 9 references

Cited by

See all 266

Metadata

Authors
Kulshreshtha, A., Vaccarino, V., Judd, S. E., Howard, V. J., McClellan, W. M., Muntner, P., Hong, Y., Safford, M. M., Goyal, A., & Cushman, M.
Venue
Stroke
Published
2013-07
Volume
44
Issue
7
Pages
1909-1914
ISSN
  • 0039-2499 (ISSN-L)
  • 1524-4628
OpenAlex
W2153708997
Cited by
266
References
9
FWCI
12.92
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Life’s Simple 7 and Risk of Incident Stroke: The Reasons for Geographic and Racial Differences in Stroke Study. https://app.cochat.ai/papers/10.1161/strokeaha.111.000352
The paper
Kulshreshtha, A., Vaccarino, V., Judd, S. E., Howard, V. J., McClellan, W. M., Muntner, P., Hong, Y., Safford, M. M., Goyal, A., & Cushman, M. (2013). Life’s Simple 7 and Risk of Incident Stroke: The Reasons for Geographic and Racial Differences in Stroke Study. Stroke. https://doi.org/10.1161/strokeaha.111.000352

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.