The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Comparison of the Berlin Definition for Acute Respiratory Distress Syndrome with Autopsy
Abstract
RATIONALE: A revised definition of clinical criteria for acute respiratory distress syndrome (ARDS), the Berlin definition, was recently established to classify patients according to their severity. OBJECTIVE: To evaluate the accuracy of these clinical criteria using diffuse alveolar damage (DAD) at autopsy as the reference standard. METHODS: All patients who died and had a clinical autopsy in our intensive care unit over a 20-year period (1991-2010) were included. Patients with clinical criteria for ARDS were identified from the medical charts and were classified as mild, moderate, or severe according to the Berlin definition using PaO2/FiO2 oxygenation criteria. Microscopic analysis from each pulmonary lobe was performed by two pathologists. MEASUREMENTS AND MAIN RESULTS: Among 712 autopsies analyzed, 356 patients had clinical criteria for ARDS at time of death, classified as mild (n = 49, 14%), moderate (n = 141, 40%), and severe (n = 166, 46%). Sensitivity was 89% and specificity 63% to identify ARDS using the Berlin definition. DAD was found in 159 of 356 (45%) patients with clinical criteria for ARDS (in 12, 40, and 58% of patients with mild, moderate, and severe ARDS, respectively). DAD was more frequent in patients who met clinical criteria for ARDS during more than 72 hours and was found in 69% of those with severe ARDS for 72 hours or longer. CONCLUSIONS: Histopathological findings were correlated to severity and duration of ARDS. Using clinical criteria the revised Berlin definition for ARDS allowed the identification of severe ARDS of more than 72 hours as a homogeneous group of patients characterized by a high proportion of DAD.
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Cites
(2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421801 · Cited by 12,941
Acute Respiratory Distress Syndrome: The Berlin Definition
(2012) · JAMA · doi:10.1001/jama.2012.5669 · Cited by 8,731
Bernard, G. R., Artigas, A., Brigham, K. L., Carlet, J., Falke, K., Hudson, L., Lamy, M., Legall, J. R., Morris, A., & Spragg, R. (1994) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.149.3.7509706 · Cited by 6,746
ACUTE RESPIRATORY DISTRESS IN ADULTS
Ashbaugh, D., Boyd Bigelow, D., Petty, T., & Levine, B. (1967) · The Lancet · doi:10.1016/s0140-6736(67)90168-7 · Cited by 4,278
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material
Ferguson, N. D., Fan, E., Camporota, L., Antonelli, M., Anzueto, A., Beale, R., Brochard, L., Brower, R., Esteban, A., Gattinoni, L., et al. (2012) · Intensive Care Medicine · doi:10.1007/s00134-012-2682-1 · Cited by 1,443
Self-citationJaeschke, R. (1994) · JAMA · doi:10.1001/jama.1994.03510290071040 · Cited by 1,049
Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury
(2006) · New England Journal of Medicine · doi:10.1056/nejmoa061895 · Cited by 980
GATTINONI, L., PELOSI, P., SUTER, P. M., PEDOTO, A., VERCESI, P., & LISSONI, A. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.1.9708031 · Cited by 900
Causes of Mortality in Patients With the Adult Respiratory Distress Syndrome
(1986) · Journal of Critical Care · doi:10.1016/s0883-9441(86)80119-8 · Cited by 805
Gajic, O., Dara, S. I., Mendez, J. L., Adesanya, A. O., Festic, E., Caples, S. M., Rana, R., St. Sauver, J. L., Lymp, J. F., Afessa, B., et al. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000133019.52531.30 · Cited by 739
Cited by
Acute respiratory distress syndrome
Matthay, M. A., Zemans, R. L., Zimmerman, G. A., Arabi, Y. M., Beitler, J. R., Mercat, A., Herridge, M., Randolph, A. G., & Calfee, C. S. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0069-0 · Cited by 2,387
Acute respiratory distress syndrome
Thompson, B. T., Chambers, R. C., & Liu, K. D. (2017) · New England Journal of Medicine · doi:10.1056/nejmra1608077 · Cited by 1,807
Calfee, C. S., Delucchi, K., Parsons, P. E., Thompson, B. T., Ware, L. B., & Matthay, M. A. (2014) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(14)70097-9 · Cited by 1,544
Polak, S. B., Van Gool, I. C., Cohen, D., von der Thüsen, J. H., & van Paassen, J. (2020) · Modern Pathology · doi:10.1038/s41379-020-0603-3 · Cited by 481
Riviello, E. D., Kiviri, W., Twagirumugabe, T., Mueller, A., Banner-Goodspeed, V. M., Officer, L., Novack, V., Mutumwinka, M., Talmor, D. S., & Fowler, R. A. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201503-0584oc · Cited by 447
Metadata
- Authors
- Thille, A. W., Esteban, A., Fernández-Segoviano, P., Rodriguez, J.-M., Aramburu, J.-A., Peñuelas, O., Cortés-Puch, I., Cardinal-Fernández, P., Lorente, J. A., & Frutos-Vivar, F.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-04-01
- Volume
- 187
- Issue
- 7
- Pages
- 761-767
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2121048953
- Cited by
- 431
- References
- 29
- FWCI
- 28.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- Thille, A. W., Esteban, A., Fernández-Segoviano, P., Rodriguez, J.-M., Aramburu, J.-A., Peñuelas, O., Cortés-Puch, I., Cardinal-Fernández, P., Lorente, J. A., & Frutos-Vivar, F. (2013). Comparison of the Berlin Definition for Acute Respiratory Distress Syndrome with Autopsy. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.201211-1981oc
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