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Profile and Predictors of Normal Ganglion Cell–Inner Plexiform Layer Thickness Measured with Frequency-Domain Optical Coherence Tomography
Open accessAbstract
PURPOSE: To describe the profile and identify the predictors of the ganglion cell-inner plexiform layer (GCIPL) thickness measured with frequency-domain optical coherence tomography (FD-OCT) in normal eyes. METHODS: Two hundred eighty-two normal subjects underwent macular and optic disc scanning in both eyes with Cirrus high-definition (HD)-OCT (Carl Zeiss Meditec, Dublin, CA). Linear regression analyses were performed to determine the association between GCIPL thickness and age, sex, ethnicity (Europeans, Africans, Hispanics, Asians, and Indians), eye laterality, refraction, intraocular pressure, axial length, central corneal thickness, mean retinal nerve fiber layer (RNFL) thickness, disc and rim areas, cup-to-disc area, vertical and horizontal cup-to-disc diameter ratios, vertical rim thickness, and OCT signal strength. RESULTS: The mean (±SD) age was 46.2 ± 16.9 years (range, 18-84 years). The mean and minimum GCIPL thicknesses (±SD) were 82.1 ± 6.2 and 80.4 ± 6.4 μm, respectively. There were significant differences in GCIPL thickness between macular sectors (P < 0.05), except between the superotemporal and inferonasal sectors (P = 0.63). The superonasal sector had the thickest and the inferior had the thinnest GCIPL. The GCIPL of the superior hemisphere was thicker than that of the inferior, and the nasal sector GCIPL was significantly thicker than the temporal one (P < 0.001). The average GCIPL did not differ between male and female subjects (P = 0.16) after adjustment for axial length and between ethnic groups (P = 0.41) after adjustment for age, axial length, and RNFL thickness. Significant predictors of mean GCIPL thickness were average RNFL thickness (β = 0.37, P < 0.001), age (β = -0.083, P < 0.001), axial length (β = -0.87, P = 0.001), and male sex (β = -1.62, P = 0.005). CONCLUSIONS: The independent factors associated with thinner GCIPL include thinner RNFL, older age, longer ocular axial length, and being male. Although the magnitude of the effect of age, axial length, and sex are small, these factors should be taken into account when interpreting Cirrus HD-OCT-based GCIPL thickness measurements.
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Citations
Cites
Topography of ganglion cells in human retina
Curcio, C. A., & Allen, K. A. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.903000103 · Cited by 1,844
Kerrigan, L. A., Quigley, H. A., Pease, M. E., Kerrigan, D., & Mitchell, R. S. (2000) · PubMed · Cited by 869
Improvements on Littmann's method of determining the size of retinal features by fundus photography
Bennett, A. G., Rudnicka, A. R., & Edgar, D. F. (1994) · Graefe's Archive for Clinical and Experimental Ophthalmology · doi:10.1007/bf00175988 · Cited by 693
Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT
Budenz, D. L., Anderson, D. R., Varma, R., Schuman, J., Cantor, L., Savell, J., Greenfield, D. S., Patella, V. M., Quigley, H. A., & Tielsch, J. (2007) · Ophthalmology · doi:10.1016/j.ophtha.2006.08.046 · Cited by 684
Self-citationThe Effect of Age on the Nerve Fiber Population of the Human Optic Nerve
Balazsi, A. G., Rootman, J., Drance, S. M., Schulzer, M., & Douglas, G. R. (1984) · American Journal of Ophthalmology · doi:10.1016/0002-9394(84)90509-9 · Cited by 502
Macular Segmentation with Optical Coherence Tomography
Ishikawa, H., Stein, D. M., Wollstein, G., Beaton, S., Fujimoto, J. G., & Schuman, J. S. (2005) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.04-0335 · Cited by 498
Self-citationHuman optic nerve fiber count and optic disc size.
Jonas, J. B., Schmidt, A. M., Müller-Bergh, J. A., Schlötzer-Schrehardt, U. M., & Naumann, G. O. H. (1992) · PubMed · Cited by 496
Perry, V. H., & Cowey, A. (1985) · Vision Research · doi:10.1016/0042-6989(85)90004-5 · Cited by 494
Kang, S. H., Hong, S. W., Im, S. K., Lee, S. H., & Ahn, M. D. (2010) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.09-4737 · Cited by 401
Retinal Nerve Fiber Layer Measurements in Myopia: An Optical Coherence Tomography Study
Leung, C. K.-S., Mohamed, S., Leung, K. S., Cheung, C. Y.-L., Chan, S. L.-W., Cheng, D. K.-Y., Lee, A. K.-C., Leung, G. Y. S., Rao, S. K., & Lam, D. S. C. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-0545 · Cited by 392
Self-citationRetinal thickness decreases with age: an OCT study
Alamouti, B. (2003) · British Journal of Ophthalmology · doi:10.1136/bjo.87.7.899 · Cited by 385
Mapping of Macular Substructures with Optical Coherence Tomography for Glaucoma Diagnosis
Tan, O., Li, G., Lu, A. T.-H., Varma, R., & Huang, D. (2008) · Ophthalmology · doi:10.1016/j.ophtha.2007.08.011 · Cited by 361
Retinal pathology in Alzheimer's disease. I. Ganglion cell loss in foveal/parafoveal retina
Blanks, J. C., Torigoe, Y., Hinton, D. R., & Blanks, R. H. I. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00010-3 · Cited by 330
The Effect of Age on Normal Human Optic Nerve Fiver Number and Diameter
Repka, M. X., & Quigley, H. A. (1989) · Ophthalmology · doi:10.1016/s0161-6420(89)32928-9 · Cited by 296
Histomorphometry of the human optic nerve.
Jonas, J. B., Müller-Bergh, J. A., Schlötzer-Schrehardt, U. M., & Naumann, G. O. H. (1990) · PubMed · Cited by 263
Mikelberg, F. S., Drance, S. M., Schulzer, M., Yidegiligne, H. M., & Weis, M. M. (1989) · Ophthalmology · doi:10.1016/s0161-6420(89)32718-7 · Cited by 263
Human Chorioretinal Layer Thicknesses Measured in Macula-wide, High-Resolution Histologic Sections
Curcio, C. A., Messinger, J. D., Sloan, K. R., Mitra, A., McGwin, G., & Spaide, R. F. (2011) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.10-6377 · Cited by 251
Sung, K. R., Wollstein, G., Bilonick, R. A., Townsend, K. A., Ishikawa, H., Kagemann, L., Noecker, R. J., Fujimoto, J. G., & Schuman, J. S. (2009) · Ophthalmology · doi:10.1016/j.ophtha.2009.01.004 · Cited by 228
Self-citationRetinal Nerve Fiber Layer Thickness in Normal Human Eyes
Varma, R., Skaf, M., & Barron, E. (1996) · Ophthalmology · doi:10.1016/s0161-6420(96)30381-3 · Cited by 219
Savini, G. (2005) · British Journal of Ophthalmology · doi:10.1136/bjo.2004.052498 · Cited by 219
Measurement of optic disc size: equivalence of methods to correct for ocular magnification
Garway‐Heath, D. F., Rudnicka, A. R., Lowe, T., Foster, P. J., Fitzke, F. W., & Hitchings, R. A. (1998) · British Journal of Ophthalmology · doi:10.1136/bjo.82.6.643 · Cited by 211
Age-related decline of human optic nerve axon populations
Johnson, B. M., Miao, M., & Sadun, A. A. (1987) · AGE · doi:10.1007/bf02431765 · Cited by 180
Thickness Profiles of Retinal Layers by Optical Coherence Tomography Image Segmentation
Bagci, A. M., Shahidi, M., Ansari, R., Blair, M., Blair, N. P., & Zelkha, R. (2008) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2008.06.010 · Cited by 180
Age-Related Losses of Retinal Ganglion Cells and Axons
Harwerth, R. S., Wheat, J. L., & Rangaswamy, N. V. (2008) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.08-1753 · Cited by 175
Neuronal density in the human retinal ganglion cell layer from 16-77 years
Harman, A. M., Abrahams, B. S., Moore, S., & Hoskins, R. V. (2000) · The Anatomical Record · doi:10.1002/1097-0185(20001001)260:2<124::aid-ar20>3.0.co;2-d · Cited by 169
Lalezary, M., Medeiros, F. A., Weinreb, R. N., Bowd, C., Sample, P. A., Tavares, I. M., Tafreshi, A., & Zangwill, L. M. (2006) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2006.05.004 · Cited by 160
Eriksson, U., & Alm, A. (2008) · British Journal of Ophthalmology · doi:10.1136/bjo.2007.131094 · Cited by 134
Larger Optic Nerve Heads Have More Nerve Fibers in Normal Monkey Eyes
Quigley, H. A., Coleman, A. L., & Dorman-Pease, M. E. (1991) · Archives of Ophthalmology · doi:10.1001/archopht.1991.01080100121056 · Cited by 127
Huang, J., Liu, X., Wu, Z., XIAO, H., Dustin, L., & Sadda, S. R. (2009) · Retina · doi:10.1097/iae.0b013e3181a2c1a7 · Cited by 108
Kim, C. Y., Kim, J. H., Lee, J., Lee, E. S., Seong, G. J., & Kim, C. Y. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6648 · Cited by 73
DeBuc, D. C., Somfai, G. M., Ranganathan, S., Tátrai, E., Ferencz, M., & Puliafito, C. A. (2009) · Journal of Biomedical Optics · doi:10.1117/1.3268773 · Cited by 63
Optic nerve fiber count and diameter of the retrobulbar optic nerve in normal and glaucomatous eyes
Jonas, J. B., Schmidt, A. M., Müller-Bergh, J. A., & Naumann, G. O. H. (1995) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/bf00180945 · Cited by 50
Kanno, M., Nagasawa, M., Suzuki, M., et al. (2010) · Japanese Journal of Ophthalmology · doi:10.1007/s10384-009-0753-9 · Cited by 21
Cited by
Glaucomatous damage of the macula
Hood, D. C., Raza, A. S., de Moraes, C. G. V., Liebmann, J. M., & Ritch, R. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2012.08.003 · Cited by 867
Self-citationA New Approach to Staging Diabetic Eye Disease
Channa, R., Wolf, R. M., Simo, R., Brigell, M., Fort, P., Curcio, C., Lynch, S., Verbraak, F., Abramoff, M. D., Abramoff, M. D., et al. (2024) · Ophthalmology Science · doi:10.1016/j.xops.2023.100420 · Cited by 26
Metadata
- Authors
- Mwanza, J.-C., Durbin, M. K., Budenz, D. L., Girkin, C. A., Leung, C. K., Liebmann, J. M., Peace, J. H., Werner, J. S., & Wollstein, G.
- Venue
- Investigative Opthalmology & Visual Science
- Published
- 2011-10-04
- Volume
- 52
- Issue
- 11
- Pages
- 7872
- ISSN
- 0146-0404 (ISSN-L)
- 1552-5783
- OpenAlex
- W2022681700
- Cited by
- 275
- References
- 33
- FWCI
- 15.52
- Type
- journal article
- Language
- en
- Open access
- bronze
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