An Adaptation of the Nitrous Oxide Method to the Study of the Cerebral Circulation in Children; Normal Values for Cerebral Blood Flow and Cerebral Metabolic Rate in Childhood1
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The relative energy and oxygen demands of the developing brain are markedly greater than those of the adult brain.
“the relative energy and oxygen demands of the developing brain are markedly greater than that of the adult brain (Kennedy and Sokoloff, 1957).”
From The Cellular and Molecular Landscapes of the Developing Human Central Nervous System (2016) · cites this paper as Kennedy and Sokoloff, 1957
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- Authors
- Kennedy, C., & Sokoloff, L.
- Affiliations
- Children's Hospital of Philadelphia (US)
- Venue
- Journal of Clinical Investigation
- Published
- 1957-07-01
- Volume
- 36
- Issue
- 7
- Pages
- 1130-1137
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC1072700
- OpenAlex
- W2144097932
- Cited by
- 300
- References
- 35
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 7 · 2023: 2 · 2022: 6 · 2021: 10 · 2020: 7 · 2019: 9 · 2018: 10 · 2017: 13 · 2016: 9 · 2015: 5 · 2014: 11 · 2013: 9 · 2012: 11
- FWCI
- 4.26
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Surgery › Biomedical and Chemical Research
- Keywords
- cerebral blood flow, cerebral metabolic rate, children, reference values, cerebral circulation, pediatric neurophysiology
- MeSH terms
- Acclimatization, Brain, Cerebrovascular Circulation, Child, Humans, Nitrous Oxide, Reference Values
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