The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium
Open accessAbstract
In a reconstituted flow chamber system, preincubation with chemokines can trigger the arrest of rolling monocytes, suggesting that this interaction could help recruit these cells to early atherosclerotic lesions. To date, however, the contribution of endothelium-derived chemokines found in these lesion to monocyte arrests has not been investigated. The endothelium of lesion-prone carotid arteries from apolipoprotein E-deficient (ApoE(-/-)) mice, but not control mice, presents the chemokines KC (mouse GRO-alpha) and JE (mouse monocyte chemoattractant protein-1 [MCP-1]). Arrest of a monocytic cell line or mouse blood monocytes perfused through carotid arteries of ApoE(-/-) mice was reduced by treating with either pertussis toxin, an antagonist of CXCR2, or an antibody to KC, but this process was insensitive to agents that blocked CCR-2 or JE. Conversely, monocyte accumulation more than doubled upon pre-perfusion of the carotid artery with KC but not with mouse MCP-1. Blockade of alpha(4)beta(1) integrin (VLA-4) or vascular cell adhesion molecule-1, but not CD18 or intercellular adhesion molecule-1, almost completely inhibited the arrest of monocytes. We conclude that when presented by early atherosclerotic lesions, KC but not murine MCP-1 triggers VLA-4-dependent monocyte recruitment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Additionally, recent studies showed effects of KC expression on monocyte recruitment during development of experimental atherosclerosis (47).”
From The IL-6–gp130–STAT3 pathway in hepatocytes triggers liver protection in T cell–mediated liver injury (2005) · cites this paper as [47]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The pathogenesis of atherosclerosis: a perspective for the 1990s
Ross, R. (1993) · Nature · doi:10.1038/362801a0 · Cited by 10,618
J Heart Lung Transplant 2021;40(4).
(2021) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2021.04.002 · Cited by 6,824
Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632
Self-citationBoring, L., Gosling, J., Cleary, M., & Charo, I. F. (1998) · Nature · doi:10.1038/29788 · Cited by 1,965
ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.
Nakashima, Y., Plump, A. S., Raines, E. W., Breslow, J. L., & Ross, R. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.14.1.133 · Cited by 1,693
Gu, L., Okada, Y., Clinton, S. K., Gerard, C. J., Sukhova, G. K., Libby, P., & Rollins, B. J. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80139-2 · Cited by 1,574
Atherosclerosis is an inflammatory disease
Ross, R. (1999) · American Heart Journal · doi:10.1016/s0002-8703(99)70266-8 · Cited by 1,458
Rg, G. (1981) · PubMed Central · Cited by 1,314
MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions
Gerszten, R. E., García-Zepeda, E. A., Lim, Y.-C., Yoshida, M., Ding, H. A., Gimbrone, M. A., Luster, A. D., Luscinskas, F. W., & Rosenzweig, A. (1999) · Nature · doi:10.1038/19546 · Cited by 1,263
Chemokines and the Arrest of Lymphocytes Rolling Under Flow Conditions
Campbell, J. J., Hedrick, J. A., Zlotnik, A., Siani, M. A., Thompson, D. A., & Butcher, E. C. (1998) · Science · doi:10.1126/science.279.5349.381 · Cited by 1,002
Research works printed but not linked: 5
- Gerrity, 1981, Am J Pathol, 103, 181
- Gerrity, 1981, Am J Pathol, 103, 191
- Johnson-Tidey, 1994, Am J Pathol, 144, 952
- Koch, 1993, Am J Pathol, 142, 1423
- Pattison, 1996, J Heart Lung Transplant, 15, 1194
Cited by
Sorted by citations
Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease
Jaiswal, S., Natarajan, P., Silver, A. J., Gibson, C. J., Bick, A. G., Shvartz, E., McConkey, M., Gupta, N., Gabriel, S., Ardissino, D., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1701719 · Cited by 2,683
The many roles of chemokines and chemokine receptors in inflammation
Charo, I. F., & Ransohoff, R. M. (2006) · New England Journal of Medicine · doi:10.1056/nejmra052723 · Cited by 2,523
Serbina, N. V., & Pamer, E. G. (2006) · Nature Immunology · doi:10.1038/ni1309 · Cited by 1,658
Immune and Inflammatory Mechanisms of Atherosclerosis
Galkina, E., & Ley, K. F. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132620 · Cited by 1,480
Self-citationTacke, F., Alvarez, D., Kaplan, T. J., Jakubzick, C., Spanbroek, R., Llodra, J., Garin, A., Liu, J., Mack, M., van Rooijen, N., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci28549 · Cited by 1,323
Self-citationBernhagen, J., Krohn, R. M., Lue, H., Gregory, J. L., Zernecke, A., Koenen, R. R., Dewor, M., Georgiev, I., Schober, A., Leng, L., et al. (2007) · Nature Medicine · doi:10.1038/nm1567 · Cited by 1,292
Self-citationC hemokines in I nnate and A daptive H ost D efense : Basic Chemokinese Grammar for Immune Cells
Rot, A., & von Andrian, U. H. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104543 · Cited by 1,209
Three or more routes for leukocyte migration into the central nervous system
Ransohoff, R. M., Kivisäkk, P., & Kidd, G. (2003) · Nature Reviews Immunology · doi:10.1038/nri1130 · Cited by 1,052
Increased Number of Islet-Associated Macrophages in Type 2 Diabetes
Ehses, J. A., Perren, A. A., Eppler, E., Ribaux, P., Pospisilik, J. A., Maor-Cahn, R., Guéripel, X., Ellingsgaard, H., Schneider, M. K. J., Biollaz, G., et al. (2007) · Diabetes · doi:10.2337/db06-1650 · Cited by 804
Chemokines in the Pathogenesis of Vascular Disease
Charo, I. F., & Taubman, M. B. (2004) · Circulation Research · doi:10.1161/01.res.0000146672.10582.17 · Cited by 758
Chemokines and chemokine receptors in leukocyte trafficking
Olson, T. S., & Ley, K. F. (2002) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00738.2001 · Cited by 670
Self-citationCombadière, C., Potteaux, S., Rodero, M. P., Simon, T., Pézard, A., Esposito, B., Merval, R., Proudfoot, A. E. I., Tedgui, A., & Mallat, Z. (2008) · Circulation · doi:10.1161/circulationaha.107.745091 · Cited by 696
Platelet-neutrophil-interactions: Linking hemostasis and inflammation
Zarbock, A., Polanowska‐Grabowska, R., & Ley, K. F. (2006) · Blood Reviews · doi:10.1016/j.blre.2006.06.001 · Cited by 652
Self-citationInflammation and Restenosis in the Stent Era
Welt, F. G. P., & Rogers, C. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000037100.44766.5b · Cited by 633
Monocyte and Macrophage Dynamics During Atherogenesis
Ley, K. F., Miller, Y. I., & Hedrick, C. C. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.221127 · Cited by 570
Self-citationMonocyte-Endothelial Cell Interactions in the Development of Atherosclerosis
Mestas, J., & Ley, K. F. (2008) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2008.11.004 · Cited by 562
Self-citationDecreased atherosclerosis in CX3CR1–/– mice reveals a role for fractalkine in atherogenesis
Lesnik, P., Haskell, C. A., & Charo, I. F. (2003) · Journal of Clinical Investigation · doi:10.1172/jci15555 · Cited by 487
Monocyte trafficking across the vessel wall
Gerhardt, T., & Ley, K. F. (2015) · Cardiovascular Research · doi:10.1093/cvr/cvv147 · Cited by 507
Self-citationGalkina, E., Kadl, A., Sanders, J., Varughese, D., Sarembock, I. J., & Ley, K. F. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20052205 · Cited by 456
Self-citationBlockade of Interleukin-17A Results in Reduced Atherosclerosis in Apolipoprotein E–Deficient Mice
Smith, E. E., Prasad, K.-M. R., Butcher, M. J., Dobrian, A. D., Kolls, J. K., Ley, K. F., & Galkina, E. (2010) · Circulation · doi:10.1161/circulationaha.109.924886 · Cited by 422
Self-citationMahad, D., & Ransohoff, R. M. (2002) · Seminars in Immunology · doi:10.1016/s1044-5323(02)00125-2 · Cited by 412
Decreased Atherosclerotic Lesion Formation in CX3CR1/Apolipoprotein E Double Knockout Mice
Combadière, C., Potteaux, S., Gao, J.-L., Esposito, B., Casanova, S., Lee, E. J., Debré, P., Tedgui, A., Murphy, P. M., & Mallat, Z. (2003) · Circulation · doi:10.1161/01.cir.0000057548.68243.42 · Cited by 476
Endothelial-Dependent Mechanisms of Leukocyte Recruitment to the Vascular Wall
Rao, R. M., Yang, L., García‐Cardeña, G., & Luscinskas, F. W. (2007) · Circulation Research · doi:10.1161/circresaha.107.151860b · Cited by 400
Tsai, H., Frost, E. E., To, V., Robinson, S., ffrench‐Constant, C., Geertman, R. T., Ransohoff, R. M., & Miller, R. H. (2002) · Cell · doi:10.1016/s0092-8674(02)00838-3 · Cited by 398
Leukocyte Recruitment and Vascular Injury in Diabetic Nephropathy
Galkina, E., & Ley, K. F. (2006) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005080859 · Cited by 376
Self-citationDeficiency of cathepsin S reduces atherosclerosis in LDL receptor–deficient mice
Sukhova, G. K., Zhang, Y., Pan, J.-H., Wada, Y., Yamamoto, T., Naito, M., Kodama, T., Tsimikas, S., Witztum, J. L., Lu, M. L., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci14915 · Cited by 374
Schober, A., Manka, D. R., von Hundelshausen, P., Huo, Y., Hanrath, P., Sarembock, I. J., Ley, K. F., & Weber, C. (2002) · Circulation · doi:10.1161/01.cir.0000028590.02477.6f · Cited by 354
Self-citationApoptotic Cells with Oxidation-specific Epitopes Are Immunogenic and Proinflammatory
Chang, M.-K., Binder, C. J., Miller, Y. I., Subbanagounder, G., Silverman, G. J., Berliner, J. A., & Witztum, J. L. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031763 · Cited by 337
Rapid recruitment of inflammatory monocytes is independent of neutrophil migration
Henderson, R. B., Hobbs, J. A. R., Mathies, M., & Hogg, N. (2003) · Blood · doi:10.1182/blood-2002-10-3228 · Cited by 309
Filippo, K. D., Henderson, R. B., Laschinger, M., & Hogg, N. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.6.4308 · Cited by 305
Bot, I., de Jager, S. C. A., Zernecke, A., Lindstedt, K. A., van Berkel, T. J. C., Weber, C., & Biessen, E. A. L. (2007) · Circulation · doi:10.1161/circulationaha.106.660472 · Cited by 286
Self-citationWang, Y., Wang, G. Z., Rabinovitch, P. S., & Tabas, I. A. (2013) · Circulation Research · doi:10.1161/circresaha.114.302153 · Cited by 264
Chemokines in Vascular Dysfunction and Remodeling
Schober, A. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.161224 · Cited by 262
Atherosclerosis as an Inflammatory Disease
Tuttolomondo, A., Raimondo, D. D., Pecoraro, R., Arnao, V., Pinto, A. V., & Licata, G. (2012) · Current Pharmaceutical Design · doi:10.2174/138161212802481237 · Cited by 263
Lu, H., Huang, D., Ransohoff, R. M., & Zhou, L. (2011) · The FASEB Journal · doi:10.1096/fj.10-178939 · Cited by 264
Hristov, M., Zernecke, A., Bidzhekov, K., Liehn, E. A., Shagdarsuren, E., Ludwig, A., & Weber, C. (2007) · Circulation Research · doi:10.1161/01.res.0000259043.42571.68 · Cited by 253
Self-citationHeterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques
Waldo, S. W., Li, Y., Buono, C., Zhao, B. N., Billings, E. M., Chang, J., & Kruth, H. S. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.070513 · Cited by 259
Weber, C., Schober, A., & Zernecke, A. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000142812.03840.6f · Cited by 246
Self-citationIntegration of inflammatory signals by rolling neutrophils
Ley, K. F. (2002) · Immunological Reviews · doi:10.1034/j.1600-065x.2002.18602.x · Cited by 242
Self-citationKoszałka, P., Özüyaman, B., Huo, Y., Zernecke, A., Flögel, U., Braun, N., Buchheiser, A., Decking, U. K. M., Smith, M. L., Sévigny, J., et al. (2004) · Circulation Research · doi:10.1161/01.res.0000144796.82787.6f · Cited by 236
Self-citationDaly, C. M., & Rollins, B. J. (2003) · Microcirculation · doi:10.1038/sj.mn.7800190 · Cited by 232
Macrophage Migration Inhibitory Factor Induces Macrophage Recruitment via CC Chemokine Ligand 2
Gregory, J. L., Morand, E. F., McKeown, S. J., Ralph, J. A., Hall, P., Yang, Y. H., McColl, S. R., & Hickey, M. J. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.11.8072 · Cited by 229
Wu, M., Chiou, H., Ho, I., Chen, C., & Lee, T. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6396 · Cited by 226
Zhou, Z., Subramanian, P., Sevilmis, G., Globke, B., Soehnlein, O., Karshovska, E., Megens, R. T. A., Heyll, K., Chun, J. J. M., Saulnier‐Blache, J. S., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.02.016 · Cited by 225
Self-citationCXCR2 antagonists for the treatment of pulmonary disease
Chapman, R. W., Phillips, J. E., Hipkin, R. W., Curran, A. K., Lundell, D., & Fine, J. S. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.10.005 · Cited by 214
Chemokines in the vascular inflammatory response of atherosclerosis
Zernecke, A., & Weber, C. (2009) · Cardiovascular Research · doi:10.1093/cvr/cvp391 · Cited by 210
Self-citationKlein, C., Wüstefeld, T., Assmus, U., Roskams, T., Rose-John, S., Müller, M., Manns, M. P., Ernst, M., & Trautwein, C. (2005) · Journal of Clinical Investigation · doi:10.1172/jci200523640 · Cited by 200
Boekholdt, S. M., Peters, R. J. G., Hack, C. E., Day, N., Luben, R., Bingham, S. A., Wareham, N. J., Reitsma, P. H., & Khaw, K. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000134294.54422.2e · Cited by 197
Jia, Z., Nallasamy, P., Liu, D., Shah, H., Li, J. Z., Chitrakar, R., Si, H., McCormick, J., Zhu, H., Wei, Z., et al. (2014) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2014.11.008 · Cited by 192
An, G., Wang, H., Tang, R., Yago, T., McDaniel, J. M., McGee, S., Huo, Y., & Xia, L. (2008) · Circulation · doi:10.1161/circulationaha.108.771048 · Cited by 191
Self-citationInflammatory Chemokines in Atherosclerosis
Gencer, S., Evans, B. R., van der Vorst, E. P. C., Döring, Y., & Weber, C. (2021) · Cells · doi:10.3390/cells10020226 · Cited by 202
Self-citationWeber, C., Kraemer, S., Drechsler, M. D., Lue, H., Koenen, R. R., Kapurniotu, A., Zernecke, A., & Bernhagen, J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804017105 · Cited by 174
Self-citationRaines, E. W., & Ferri, N. (2005) · Journal of Lipid Research · doi:10.1194/jlr.r500004-jlr200 · Cited by 186
Weber, C. (2003) · Journal of Molecular Medicine · doi:10.1007/s00109-002-0391-x · Cited by 172
Self-citationLocal adipose tissue depots as cardiovascular risk factors
Thalmann, S., & MEIER, C. (2007) · Cardiovascular Research · doi:10.1016/j.cardiores.2007.03.008 · Cited by 166
Abu-Taha, M. I., Rius, C., Hermenegildo, C., Noguera, I., Cerdá‐Nicolás, M., Issekutz, A. C., Jose, P. J., Cortijo, J., Morcillo, E. J., & Sanz, M. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803157 · Cited by 161
Chemokines and Chemokine Receptors: Multipurpose Players in Neuroinflammation
Ransohoff, R. M., Liu, L., & Cardona, A. E. (2007) · International review of neurobiology · doi:10.1016/s0074-7742(07)82010-1 · Cited by 163
Akhtar, S., Hartmann, P., Karshovska, E., Rinderknecht, F.-A. B., Subramanian, P., Gremse, F., Grommes, J., Jacobs, M. J. H. M., Kiessling, F. M., Weber, C., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05886 · Cited by 157
Self-citationRegulation of endothelial progenitor cell homing after arterial injury
Hristov, M., Zernecke, A., Liehn, E. A., & Weber, C. (2007) · Thrombosis and Haemostasis · doi:10.1160/th07-03-0181 · Cited by 151
Self-citationLucas, A., Bursill, C. A., Guzik, T. J., Sadowski, J., Channon, K. M., & Greaves, D. R. (2003) · Circulation · doi:10.1161/01.cir.0000097119.57756.ef · Cited by 154
Therapeutic targeting of chemokine interactions in atherosclerosis
Koenen, R. R., & Weber, C. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3048 · Cited by 153
Self-citationChemokines in vascular remodeling
Zernecke, A., & Schober, A. (2007) · Thrombosis and Haemostasis · doi:10.1160/th07-02-0085 · Cited by 151
Reilly, K. B., Srinivasan, S. R., Hatley, M. E., Patricia, M. K., Lannigan, J. A., Bolick, D. T., Vandenhoff, G. E., Pei, H., Natarajan, R. D., Nadler, J. L., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m303857200 · Cited by 147
Deep Vein Thrombosis Resolution Is Modulated by Monocyte CXCR2-Mediated Activity in a Mouse Model
Henke, P. K., Varga, A. J., De, S. K., Deatrick, C. B., Eliason, J. L., Arenberg, D. A., Sukheepod, P., Thanaporn, P., Kunkel, S. L., Upchurch, G. R., et al. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000129537.72553.73 · Cited by 147
Oxidized Phospholipids Trigger Atherogenic Inflammation in Murine Arteries
Fürnkranz, A., Schober, A., Bochkov, V. N., Bashtrykov, P., Krönke, G., Kadl, A., Binder, B. R., Weber, C., & Leitinger, N. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000153106.03644.a0 · Cited by 143
Self-citationSchober, A., Zernecke, A., Liehn, E. A., von Hundelshausen, P., Knarren, S., Kuziel, W. A., & Weber, C. (2004) · Circulation Research · doi:10.1161/01.res.0000149518.86865.3e · Cited by 139
Self-citationHartmann, P., Zhou, Z., Natarelli, L., Wei, Y., Nazari-Jahantigh, M., Zhu, M., Grommes, J., Steffens, S., Weber, C., & Schober, A. (2016) · Nature Communications · doi:10.1038/ncomms10521 · Cited by 140
Self-citationGalkina, E., Harry, B. L., Ludwig, A., Liehn, E. A., Sanders, J. M., Bruce, A. C., Weber, C., & Ley, K. F. (2007) · Circulation · doi:10.1161/circulationaha.106.678474 · Cited by 136
Self-citationModulation of Atherogenesis by Chemokines
Boisvert, W. A. (2004) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2004.02.006 · Cited by 135
GRO family chemokines are specialized for monocyte arrest from flow
Smith, D. F., Galkina, E., Ley, K. F., & Huo, Y. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00153.2005 · Cited by 132
Self-citationLaudanna, C., & Alon, R. (2005) · Thrombosis and Haemostasis · doi:10.1160/th05-07-0482 · Cited by 129
The role of monocytes in atherosclerotic coronary artery disease
Pamukçu, B., Lip, G. Y. H., Devitt, A., Griffiths, H. R., & Shantsila, E. (2010) · Annals of Medicine · doi:10.3109/07853890.2010.497767 · Cited by 127
Bolick, D. T., Srinivasan, S. R., Kim, K. W., Hatley, M. E., Clemens, J. J., Whetzel, A. M., Ferger, N., Macdonald, T. L., Davis, M. D., Tsao, P. S., et al. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000162171.30089.f6 · Cited by 119
Blanchet, X., Langer, M., Weber, C., Koenen, R. R., & von Hundelshausen, P. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00175 · Cited by 121
Self-citationZeiffer, U., Schober, A., Lietz, M., Liehn, E. A., Erl, W., Emans, N., Yan, Z.-Q., & Weber, C. (2004) · Circulation Research · doi:10.1161/01.res.0000121105.72718.5c · Cited by 118
Self-citationHatley, M. E., Srinivasan, S. R., Reilly, K. B., Bolick, D. T., & Hedrick, C. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301175200 · Cited by 116
Potteaux, S., Combadière, C., Esposito, B., Lécureuil, C., Ait‐Oufella, H., Merval, R., Ardouin, P., Tedgui, A., & Mallat, Z. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000231527.22762.71 · Cited by 122
Dual targeting of CCR2 and CCR5: therapeutic potential for immunologic and cardiovascular diseases
Zhao, Q. (2010) · Journal of Leukocyte Biology · doi:10.1189/jlb.1009671 · Cited by 113
CXCL5 limits macrophage foam cell formation in atherosclerosis
Rousselle, A., Qadri, F., Leukel, L., Yılmaz, R., Fontaine, J., Sihn, G., Bäder, M., Ahluwalia, A., & Duchêne, J. (2013) · Journal of Clinical Investigation · doi:10.1172/jci66580 · Cited by 114
Effect of C-reactive protein on chemokine expression in human aortic endothelial cells
Devaraj, S. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2003.12.005 · Cited by 113
Glucose Regulates Monocyte Adhesion Through Endothelial Production of Interleukin-8
Srinivasan, S. R., Yeh, M. W., Danziger, E. C., Hatley, M. E., Riggan, A. E., Leitinger, N., Berliner, J. A., & Hedrick, C. C. (2003) · Circulation Research · doi:10.1161/01.res.0000061714.74668.5c · Cited by 102
Charo, I. F., & Peters, W. (2003) · Microcirculation · doi:10.1038/sj.mn.7800191 · Cited by 100
Lin, M., Carlson, E. C., Diaconu, E., & Pearlman, E. M. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.0806502 · Cited by 98
Jia, Z., Babu, P. V. A., Si, H., Nallasamy, P., Zhu, H., Wei, Z., Misra, H. P., Li, Y., & Liu, D. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.03.035 · Cited by 99
Inflammatory mediators in atherosclerotic vascular disease
Zernecke, A., & Weber, C. (2005) · Basic Research in Cardiology · doi:10.1007/s00395-005-0511-6 · Cited by 94
Self-citationLysophosphatidic acid in atherosclerotic diseases
Schober, A., & Siess, W. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.02021.x · Cited by 93
Induction of dendritic cell-like phenotype in macrophages during foam cell formation
Cho, H., Shashkin, P. N., Gleissner, C. A., Dunson, D., Jain, N., Lee, J. K., Miller, Y. I., & Ley, K. F. (2007) · Physiological Genomics · doi:10.1152/physiolgenomics.00051.2006 · Cited by 92
Self-citationKorbecki, J., Maruszewska, A., Bosiacki, M., Chlubek, D., & Baranowska‐Bosiacka, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010205 · Cited by 90
Zhang, K., Li, T. X., Liu, L., Feng, Y., Dong, Y.-B., Li, B., Shang, D., Fang, W., Cao, Y., & Chen, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072744 · Cited by 89
Schröder, K., Vecchione, C., Jung, O., Schreiber, J. G., Shiri‐Sverdlov, R., van Gorp, P. J., Busse, R., & Brandes, R. P. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.03.026 · Cited by 86
Papadopoulou, C., Corrigall, V., Taylor, P. R., & Poston, R. N. (2008) · Cytokine · doi:10.1016/j.cyto.2008.05.009 · Cited by 83
Liehn, E. A., Schober, A., & Weber, C. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000143135.71440.75 · Cited by 83
Self-citationChemokine-like functions of MIF in atherosclerosis
Schober, A., Bernhagen, J., & Weber, C. (2008) · Journal of Molecular Medicine · doi:10.1007/s00109-008-0334-2 · Cited by 82
Self-citationSmith, D. F., Deem, T. L., Bruce, A. C., Reutershan, J., Wu, D. D., & Ley, K. F. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.0306227 · Cited by 82
Self-citationChemokines and microRNAs in atherosclerosis
Hartmann, P., Schober, A., & Weber, C. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1925-z · Cited by 82
Self-citationCXCL1 promotes arteriogenesis through enhanced monocyte recruitment into the peri-collateral space
Vries, M. H. M., Wagenaar, A., Verbruggen, S. E. L., Molin, D. G. M., & Post, M. J. (2014) · Angiogenesis · doi:10.1007/s10456-014-9454-1 · Cited by 81
Aspects on pathophysiological mechanisms in COPD
Larsson, K. (2007) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2007.01837.x · Cited by 83
Chemokine regulation of atherosclerosis
Barlic, J., & Murphy, P. M. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.1206761 · Cited by 80
Liehn, E. A., Merx, M. W., Postea, O., Becher, S., Djalali-Talab, Y., Shagdarsuren, E., Kelm, M., Zernecke, A., & Weber, C. (2007) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2007.00194.x · Cited by 79
Self-citationG2A Deficiency in Mice Promotes Macrophage Activation and Atherosclerosis
Bolick, D. T., Skaflen, M. D., Johnson, L. E., Kwon, S., Howatt, D. A., Daugherty, A., Ravichandran, K. S., & Hedrick, C. C. (2008) · Circulation Research · doi:10.1161/circresaha.108.181131 · Cited by 78
Metadata
- Authors
- Huo, Y., Weber, C., Forlow, S. B., Sperandio, M., Thatte, J., Mack, M., Jung, S., Littman, D. R., & Ley, K.
- Affiliations
- University of Virginia (US)
- RWTH Aachen University (DE)
- Ludwig-Maximilians-Universität München (DE)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Ley, Klaus
- ORCID
- Venue
- Journal of Clinical Investigation
- Published
- 2001-11-01
- Volume
- 108
- Issue
- 9
- Pages
- 1307-1314
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC209441
- OpenAlex
- W2117908470
- Cited by
- 266
- References
- 50
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 5 · 2019: 4 · 2018: 6 · 2017: 8 · 2016: 5 · 2015: 11 · 2014: 9 · 2013: 12 · 2012: 17
- FWCI
- 5.30
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- RWTH Publications (RWTH Aachen) (submittedVersion)
- Funders
- American Heart Association (HL-58108)
- Deutsche Forschungsgemeinschaft
- University of British Columbia
- National Institutes of Health (58108)
- National Heart, Lung, and Blood Institute (HL 58108, R01HL058108)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Health Sciences › Medicine › Oncology › Chemokine receptors and signaling
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Keywords
- MCP-1, atherosclerosis, CXCR2, VLA-4, alpha4beta1 integrin, monocyte recruitment, ApoE-deficient mice, carotid artery, pertussis toxin, CCR2, VCAM-1, CD18, ICAM-1
- MeSH terms
- Animals, Antibodies, Monoclonal, Arteriosclerosis, Carotid Arteries, Cell Adhesion, Cell Line, Chemotactic Factors, Endothelium, Vascular, Growth Substances, Humans, Mice, Inbred C57BL, Monocytes, Virulence Factors, Bordetella, Protein Binding, Time Factors, Integrins, Receptors, Lymphocyte Homing, CD18 Antigens, Chemokine CCL2, Chemokines, CXC, Receptors, Interleukin-8B, Intercellular Signaling Peptides and Proteins, Pertussis Toxin, Integrin alpha4beta1, Mice, Rats, Chemokine CXCL1
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review