Ley, Klaus

Getting to the site of inflammation: the leukocyte adhesion cascade updated

Ley, K., Laudanna, C., Cybulsky, M. I., & Nourshargh, S. (2007) · Nature Reviews Immunology

Cell Adhesion Molecules ResearchChemokine receptors and signaling

Cited by 4,354

Development of Monocytes, Macrophages, and Dendritic Cells

Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010) · Science

Immune cells in cancerImmunotherapy and Immune Responses

Cited by 3,049

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

Orecchioni, M., Ghosheh, Y., Pramod, A. B., & Ley, K. (2019) · Frontiers in Immunology

Immune cells in cancerImmune Response and Inflammation

Cited by 2,063

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis

Cochain, C., Vafadarnejad, E., Arampatzi, P., Pelisek, J., Winkels, H., Ley, K., Wolf, D., Saliba, A.-E., & Zernecke, A. (2018) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 894

Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

Meng, F., Wang, K., Aoyama, T., Grivennikov, S. I., Paik, Y., Scholten, D., Cong, M., Iwaisako, K., Liu, X., Zhang, M., et al. (2012) · Gastroenterology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 711

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry

Winkels, H., Ehinger, E., Vassallo, M., Buscher, K., Dinh, H. Q., Kobiyama, K., Hamers, A. A. J., Cochain, C., Vafadarnejad, E., Saliba, A.-E., et al. (2018) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesSingle-cell and spatial transcriptomics

Cited by 547

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

Que, X., Hung, M.-Y., Yeang, C., Gonen, A., Prohaska, T. A., Sun, X., Diehl, C., Määttä, A., Gaddis, D. E., Bowden, K., et al. (2018) · Nature

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 529

Role of β7 Integrins in Intestinal Lymphocyte Homing and Retention

Gorfu, G., Rivera-Nieves, J., & Ley, K. (2009) · Current Molecular Medicine

Cell Adhesion Molecules ResearchT-cell and B-cell Immunology

Cited by 292

The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium

Huo, Y., Weber, C., Forlow, S. B., Sperandio, M., Thatte, J., Mack, M., Jung, S., Littman, D. R., & Ley, K. (2001) · Journal of Clinical Investigation

Atherosclerosis and Cardiovascular DiseasesChemokine receptors and signaling

Cited by 266

SAMP1/YitFc mouse strain: A spontaneous model of Crohnʼs disease-like ileitis

Pizarro, T. T., Pastorelli, L., Bamias, G., Garg, R. R., Reuter, B. K., Mercado, J. R., Chieppa, M., Arseneau, K. O., Ley, K., & Cominelli, F. (2011) · Inflammatory Bowel Diseases

Inflammatory Bowel DiseaseOcular Diseases and Behçet’s Syndrome

Cited by 192

CXCL4 Downregulates the Atheroprotective Hemoglobin Receptor CD163 in Human Macrophages

Gleissner, C. A., Shaked, I., Erbel, C., Böckler, D., Katus, H. A., & Ley, K. (2010) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesChemokine receptors and signaling

Cited by 165

Tyrosine kinase Btk regulates E-selectin–mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathways

Mueller, H., Stadtmann, A., Van Aken, H., Hirsch, E., Wang, D., Ley, K., & Zarbock, A. (2010) · Blood

Cell Adhesion Molecules ResearchPlatelet Disorders and Treatments

Cited by 164

Leukocyte Influx in Atherosclerosis

Galkina, E., & Ley, K. (2007) · Current Drug Targets

Atherosclerosis and Cardiovascular DiseasesChemokine receptors and signaling

Cited by 118

Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis

Quintar, A., McArdle, S., Wolf, D., Marki, A., Ehinger, E., Vassallo, M., Miller, J., Mikulski, Z., Ley, K., & Buscher, K. (2017) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCell Adhesion Molecules Research

Cited by 109

Identification of human exTreg cells as CD16+CD56+ cytotoxic CD4+ T cells

Freuchet, A., Roy, P., Armstrong, S. S., Oliaeimotlagh, M., Kumar, S., Orecchioni, M., Ali, A. J., Khan, A., Makings, J., Lyu, Q., et al. (2023) · Nature Immunology

T-cell and B-cell ImmunologyAtherosclerosis and Cardiovascular Diseases

Cited by 72

Corrigendum: Macrophage polarization: Different gene signatures in M1 (LPS+) vs. classically and M2 (LPS–) vs. alternatively activated macrophages

Orecchioni, M., Ghosheh, Y., Pramod, A. B., & Ley, K. (2020) · Frontiers in Immunology

Immune cells in cancerImmune Response and Inflammation

Cited by 71

Regulatory T Cell Stability and Plasticity in Atherosclerosis

Ali, A. J., Makings, J., & Ley, K. (2020) · Cells

Atherosclerosis and Cardiovascular DiseasesT-cell and B-cell Immunology

Cited by 65

Atherosclerosis in the single-cell era

Winkels, H., Ehinger, E., Ghosheh, Y., Wolf, D., & Ley, K. (2018) · Current Opinion in Lipidology

Atherosclerosis and Cardiovascular DiseasesSingle-cell and spatial transcriptomics

Cited by 54

Neutrophilic Granulocytes Modulate Invariant NKT Cell Function in Mice and Humans

Wingender, G., Hiss, M., Engel, I., Peukert, K., Ley, K., Haller, H., Kronenberg, M., & von Vietinghoff, S. (2012) · The Journal of Immunology

T-cell and B-cell ImmunologyImmunotoxicology and immune responses

Cited by 52