The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
Contribution of adipogenesis to healthy adipose tissue expansion in obesity
Open accessAbstract
The manner in which white adipose tissue (WAT) expands and remodels directly impacts the risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT is associated with increased risk for insulin resistance, whereas subcutaneous WAT expansion is protective. Moreover, pathologic WAT remodeling, typically characterized by adipocyte hypertrophy, chronic inflammation, and fibrosis, is associated with insulin resistance. Healthy WAT expansion, observed in the "metabolically healthy" obese, is generally associated with the presence of smaller and more numerous adipocytes, along with lower degrees of inflammation and fibrosis. Here, we highlight recent human and rodent studies that support the notion that the ability to recruit new fat cells through adipogenesis is a critical determinant of healthy adipose tissue distribution and remodeling in obesity. Furthermore, we discuss recent advances in our understanding of the identity of tissue-resident progenitor populations in WAT made possible through single-cell RNA sequencing analysis. A better understanding of adipose stem cell biology and adipogenesis may lead to novel strategies to uncouple obesity from metabolic disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“The distribution of body fat in obesity is closely correlated with metabolic health. The expansion of visceral fat depots increases risks for metabolic disorders, whereas subcutaneous fat depots pose lesser risks or can even offer protection (Vishvanath and Gupta, 2019).”
From Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity (2025) · cites this paper as Vishvanath and Gupta, 2019
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function
Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481
Adipokines in inflammation and metabolic disease
Ouchi, N., Parker, J. L., Lugus, J. J., & Walsh, K. (2011) · Nature Reviews Immunology · doi:10.1038/nri2921 · Cited by 4,625
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
Tontonoz, P., Hu, E., & Spiegelman, B. M. (1994) · Cell · doi:10.1016/0092-8674(94)90006-x · Cited by 3,564
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
Wu, J., Boström, P., Sparks, L. M., Li, Y., Choi, J. H., Giang, A.-H., Khandekar, M. J., Virtanen, K. A., Nuutila, P., Schaart, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.05.016 · Cited by 3,406
What we talk about when we talk about fat
Rosen, E. D., & Spiegelman, B. M. (2014) · Cell · doi:10.1016/j.cell.2013.12.012 · Cited by 2,373
Dynamics of fat cell turnover in humans
Spalding, K. L., Arner, E., Westermark, P. O., Bernard, S., Buchholz, B. A., Bergmann, O., Blomqvist, L., Hoffstedt, J., Näslund, E., Britton, T., et al. (2008) · Nature · doi:10.1038/nature06902 · Cited by 2,357
Adipose tissue remodeling and obesity
Sun, K., Kusminski, C. M., & Scherer, P. E. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45887 · Cited by 1,941
Adipogenesis and metabolic health
Ghaben, A. L., & Scherer, P. E. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0093-z · Cited by 1,395
Barroso, I., Gurnell, M., Crowley, V. E. F., Agostini, M., Schwabe, J. W., Soos, M. A., Maslen, G. L., Williams, T. D. M., Lewis, H., Schafer, A. J., et al. (1999) · Nature · doi:10.1038/47254 · Cited by 1,368
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
Kim, J.-Y., van de Wall, E., Laplante, M., Azzara, A., Trujillo, M. E., Hofmann, S. M., Schraw, T., Durand, J. L., Li, H., Li, G., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31021 · Cited by 1,310 · cited 1×
“These engineered animals are more or equally obese compared with their control littermates, but metabolically healthy (56–59).”
Background
Flagged first, then by citations
Cited by
Sorted by citations
Items 401–500 of 556
Cheng, Y., Zhang, K., Liu, J., & Liu, G. (2025) · Journal of Endocrinological Investigation · doi:10.1007/s40618-025-02568-7 · Cited by 2
Regulation of adipogenesis by nucleotides
Pinette, J. A., Bryant, H. G., Myers, J. W., & Zaganjor, E. (2025) · Biochemical Society Transactions · doi:10.1042/bst20253045 · Cited by 2
Yi, X., Ling, J., Meng, H., Wu, L., Zhu, S., & Zhu, L. (2022) · Obesity Surgery · doi:10.1007/s11695-022-06003-1 · Cited by 2
So, J., Strobel, O., Wann, J., Kim, K., Paul, A., Acri, D. J., Dabin, L. C., Kim, J., & Roh, H. C. (2024) · eLife · doi:10.7554/elife.97981.1 · Cited by 2
Cordero, O. J., Kotrulev, M., & Gomez-Touriño, I. M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137093 · Cited by 2
New Insights into Adipose Tissue Metabolic Function and Dysfunction, 2nd Edition
Pallio, G., & Mannino, F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25179258 · Cited by 2
Vascular-Adipose Crosstalk: Angiogenesis and Adipose Tissue Remodeling
Fitzgibbons, T. P., Kogan, S., & Tran, K. V. (2025) · Circulation Research · doi:10.1161/circresaha.124.325899 · Cited by 2
Wafer, R., Tandon, P., & Minchin, J. E. N. (2025) · eLife · doi:10.7554/elife.107327 · Cited by 3
Teklu, M., Zhou, W., Kapoor, P., Patel, N. H., Playford, M. P., Sorokin, A. V., Dey, A., Teague, H., Manyak, G. A., Rodante, J. A., et al. (2021) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2021.100231 · Cited by 1
Roca-Rivada, A., Cruzeiro, M. D., Denis, R., Zhang, Q., Rouault, C., Rouillé, Y., Launay, J., Cruciani‐Guglielmacci, C., Mattot, V., Clément, K., et al. (2024) · JCI Insight · doi:10.1172/jci.insight.168418 · Cited by 1
Xiang, Y., Shen, L., Xue, Y., Wang, Z., Zhou, R., Cao, Y. Z., Zhu, Z., Xu, P., Yu, X., Fang, P., et al. (2024) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15881 · Cited by 1
Sakata, K., & Fukuchi, M. (2024) · Genes to Cells · doi:10.1111/gtc.13162 · Cited by 1
Nakajima, K., Takahashi, K., Tanaka, M., Kawashima, M., Machida, K., Nakao, Y., Takubo, K., & Goda, N. (2025) · The Journal of Biochemistry · doi:10.1093/jb/mvaf015 · Cited by 1
González-Arceo, M., Aguirre, L., Ibarruri, J., Cebrían, M., Martín, M. Á., Portillo, M. P., & Gómez‐Zorita, S. (2025) · Scientific Reports · doi:10.1038/s41598-025-10202-y · Cited by 1
Todurov, Plehutsa, О. І., Pylypchuk, & Hrynevych, A. A. (2025) · Diabetes Obesity Metabolic Syndrome · doi:10.57105/2415-7252-2025-4-03 · Cited by 1
Хіміч, С. Д., Polishchuk, I. V., Malyshevsky, I. O., Funikov, A. V., & Olkhomyak, O. O. (2025) · Reports of Vinnytsia National Medical University · doi:10.31393/reports-vnmedical-2025-29(3)-09 · Cited by 1
The transcription factor CUX1 exerts opposing roles in human and mouse adipocyte differentiation
Chen, Y., Liu, L., Calhoun, R. P., Cheng, L., Steger, D. J., & Seale, P. (2025) · Molecular Metabolism · doi:10.1016/j.molmet.2025.102290 · Cited by 1
Lei, Y., Gan, M., Wang, K., Liao, T., Yang, Y., Zhao, X., Zhang, X., Chen, D., Wang, X., Ma, J., et al. (2025) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-025-00835-2 · Cited by 1
Peng, Z. Y., Zhang, H., Ding, Y., Liu, Z., & Xie, M. (2026) · Cell Reports · doi:10.1016/j.celrep.2025.116801 · Cited by 1
Gm15441 improves adipogenesis and insulin sensitivity by TXNIP regulation in white adipose tissue
Shi, Y., Huang, L., Yang, X., Zhang, J., & Chen, L. (2026) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2026.159718 · Cited by 1
Shi, H., Tang, J., Yan, X., Ke, T., Mao, D., DeLing, K. O. N. G., & Li, C. (2026) · Communications Biology · doi:10.1038/s42003-026-09749-x · Cited by 1
Taege, N., Britsemmer, J. H., Israel, A., Krause, C., Junge, S., Feuchtinger, A., Ussar, S., Pfluger, P. T., Gemoll, T., Schriever, S. C., et al. (2026) · iScience · doi:10.1016/j.isci.2026.115101 · Cited by 1
miR-10b-5p regulates adipocyte lineage commitment and adipogenesis via targeting of Gata6 and Tubby
Kalenderoglou, N., Dimitri, F., Gonzalez, C. N., Vidal‐Puig, A., Hobbs, J., Younis, A. Z., Christodoulides, C., Carobbio, S., & Christian, M. (2026) · Cell Communication and Signaling · doi:10.1186/s12964-026-02834-y · Cited by 1
Barros, H. D. D. F. Q., Casagrande, B. P., Araújo, D. D., Mutran, T. A. J., Telles, M. M., Estadella, D., & Pisani, L. P. (2026) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-026-10038-5 · Cited by 3
Mesenteric adipose tissue: from protective gatekeeper to driver of inflammatory bowel disease
Gliniak, C. M. (2026) · Immunometabolism · doi:10.1097/in9.0000000000000081 · Cited by 1
Assessment of the obesogenic properties of PFAS using an in vitro-based testing strategy
Lentz, S. B. I., Bil, W., Bokkers, B. G. H., van Merode, K., Kamstra, J. H., & Legler, J. (2026) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2026.106142 · Cited by 1
Abdallah, H., Khalil, M., Mahdi, L., Pietragalla, G., Faienza, M. F., Garruti, G., & Portincasa, P. (2026) · Nutrients · doi:10.3390/nu18142317 · Cited by 1
Muoio, F., Panella, S., Harder, Y., & Tallone, T. (2021) · Biologics · doi:10.3390/biologics1020008 · Cited by 1
Physiology of obesity and metabolism
Chu, J. J., & Mehrzad, R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90965-5.00004-0 · Cited by 1
Temporal and spatial metabolite dynamics impart control in adipogenesis
Eckel‐Mahan, K. L. (2022) · The Journal of Cell Biology · doi:10.1083/jcb.202210021 · Cited by 1
Boubertakh, B., Courtemanche, O., Marsolais, D., Marzo, V. D., & Silvestri, C. (2023) · Journal of Lipid Research · doi:10.1016/j.jlr.2023.100444 · Cited by 1
The Expanding Problem of Regional Adiposity: Revisiting a 1985 Diabetes Classic by Ohlson et al.
Gupta, O. T., & Gupta, R. K. (2024) · Diabetes · doi:10.2337/dbi24-0021 · Cited by 1
Self-citationMicro/Nanobubble-Assisted Lipotransfer
Halaseh, F. F., Sherafat, A. A., Zaki, D. P., Alaniz, L., Rahimian, H., Tang, J., Arora, J. S., Sayadi, L. R., Evans, G. R. D., Ziegler, M. E., et al. (2024) · Annals of Plastic Surgery · doi:10.1097/sap.0000000000004145 · Cited by 1
Comprehensive understanding of context-specific functions of PHF2 in lipid metabolic tissues
Jeong, D., Yun, J.-E., Lee, K. H., Moon, G. H., Hong, K. Y., Park, J., Fukuda, J., Lee, Y. S., & Chun, Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-93438-y · Cited by 1
Rocha, K. C. E., Tan, B., Kempf, J., Medina, C., Beldona, V., Qian, C., Duan, Y., Xiang, Q., Yoo, A., Du, X., et al. (2025) · Molecular Metabolism · doi:10.1016/j.molmet.2025.102246 · Cited by 1
Adipose Tissue and Cancer Cachexia: What Nurses Need to Know
McClement, S. (2021) · Asia-Pacific Journal of Oncology Nursing · doi:10.4103/apjon.apjon-2134 · Cited by 1
Seyres, D., Cabassi, A., Lambourne, J. J., Burden, F., Farrow, S., McKinney, H., Batista, J., Kempster, C., Pietzner, M., Slingsby, O. C., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.06.961805 · Cited by 1
Liu, Y., Lin, D. W., Wang, H., Zhang, H., Deng, T., Liu, R., Ning, T., Bai, M., Ying, G., & Ba, Y. (2020) · doi:10.21203/rs.3.rs-42455/v1 · Cited by 1
Igf2 regulates early postnatal DPP4 + preadipocyte pool expansionPreprint
Altun, I., Vo, K. H. D., Walia, S., Yan, X., Singh, I., Karlina, R., Miok, V., Kang, L., Reichenbach, V. K., Israel, A., et al. (2025) · Genes & Development · doi:10.1101/gad.352710.125 · Cited by 1
Татарчук, Т. Ф., Косей, Н. В., Regeda, S. I., Tutchenko, T. М., & Glamazda, M. (2020) · Scientific digest of association of obstetricians and gynecologists of Ukraine · doi:10.35278/2664-0767.1(45).2020.212250
Delcourt, M., Delsinne, V., Colet, J., Declèves, A., & Tagliatti, V. (2021) · Biomolecules · doi:10.3390/biom11050662
da Silva, L., Vanzella, L. M., Lima, M. F., Nogueira, A. M., de Almeida, N. S., Guilhermo, R. D. A. R., Leite, I. O., & Toledo, A. C. C. G. (2021) · Research Society and Development · doi:10.33448/rsd-v10i5.15064
Obésité métaboliquement normale
Scheen, A. J., Esser, N., & Paquot, N. (2021) · Elsevier eBooks · doi:10.1016/b978-2-294-76753-1.00052-7
Adipose tissue: Structure, function and metabolism
Frühbeck, G., & Gómez‐Ambrosi, J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821848-8.00064-0
Fgf6 Promotes Adipocyte Progenitor Cell Proliferation for Adipose Tissue HomeostasisPreprint
Liu, C., Meng, M., Xu, B., Li, G., Cao, Y., Wang, D., Qiu, J., Yu, J., Xu, L., Ma, X., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4058692
Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life
Inaba, M., & Mori, K. (2021) · MDPI eBooks · doi:10.3390/books978-3-0365-2345-3
Liu, Y., Lin, D., Zhang, H., Wang, H., Deng, T., Liu, R., Ning, T., Bai, M., Ying, G., & Ba, Y. (2020) · Research Square · doi:10.21203/rs.3.rs-89813/v1
Liu, Y., Lin, D., Wang, H., Zhang, H., Deng, T., Liu, R., Ning, T., Bai, M., Ying, G., & Ba, Y. (2020) · doi:10.21203/rs.3.rs-103656/v1
Macchi, C., Moregola, A., Greco, M. F., Svecla, M., Bonacina, F., Dhup, S., Dadhich, R. K., Audano, M., Sonveaux, P., Mauro, C., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3910128
Microbiota intestinal y modulación del tejido adiposo en la patogénesis de la obesidad
Leonario-Rodriguez, M., & Saavedra, N. (2022) · Archivos Latinoamericanos de Nutrición · doi:10.37527/2022.72.2.004 · Cited by 1
Growth of meat animals/adipose tissue development
Chen, Y.-J., Liao, P.-X., Mersmann, H. J., Chen, C., & Ding, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85125-1.00059-4
Yao, X., Mai, X., Tian, Y., Liu, Y., Jin, G., Li, Z., Chen, S., Dai, X., Jin, X., Huang, L., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.20.558627
Loss of CTRP10 results in female obesity with preserved metabolic healthPreprint
Chen, F., Sarver, D. C., Saqib, M., Vélez, L. M., Aja, S. M., Seldin, M. M., & Wong, G. W. (2024) · eLife · doi:10.7554/elife.93373.1
Sagñay-Novillo, A. F., Vermudez-Pirela, V. J., & Patricia-Elizabeth, V. I. (2024) · MQRInvestigar · doi:10.56048/mqr20225.8.1.2024.1343-1359
Yao, T., Wei, D., Tian, X., Zhao, L., Wan, Q., Zhang, X., Cai, J., Li, S., Diao, B., Feng, S., et al. (2024) · Lipids in Health and Disease · doi:10.1186/s12944-024-02069-1
Zhu, L., Feng, Z., Shu, X. Y., Gao, Q., Wu, J., Du, Z., Li, R., Wang, L., Chen, N., Li, Y., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14992777
Zhu, L., Feng, Z., Shu, X. Y., Gao, Q., Wu, J., Du, Z., Li, R., Wang, L., Chen, N., Li, Y., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14992774
Lambert, J. M., Kovilakath, A., Jamil, M., Valentine, Y. A., Anderson, A. K., Montefusco, D. J., & Cowart, L. A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.13.612482
Chun, J., Kim, B., Jeong, M., & Kim, Y. S. (2024) · Natural Product Sciences · doi:10.20307/nps.2024.30.3.212
So, J., Strobel, O., Wann, J., Kim, K., Paul, A., Acri, D. J., Dabin, L. C., Peng, G., Kim, J., & Roh, H. C. (2024) · eLife · doi:10.7554/elife.97981.2
Spop deficiency impairs adipogenesis and promotes thermogenic capacity in mice
Li, Q., Liu, Y., Wang, Y., Zhang, Q., Zhang, N., Song, D., Wang, F., Gao, Q., Chen, Y., Zhang, G., et al. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011514
Kim, N. K., Baek, K., Lee, A. Y., Kim, H. Y., & Kim, J. H. (2024) · Journal of Korean Medicine for Obesity Research · doi:10.15429/jkomor.2024.24.2.121
Shen, C., Nie, K., Wang, H., Gao, Y., Jiang, X., Su, H., Wang, Z., Tang, Y., Lu, F., Dong, H., et al. (2025) · Chinese Medicine · doi:10.1186/s13020-024-01053-2
Braud, L., Bernabe, M., Vernerey, J., Miranda, A. M. A., Dominguez, A., Churikov, D., Richaud, M., McAllan, L., Lachaud, C., Gil, J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.06.631346
The role of adiposopathy in the development of obesity-related diseases
Kim, O. T., Дадаева, В. А., Ивановна, Л. Д., & Drapkina, O. M. (2025) · Russian Journal of Preventive Medicine · doi:10.17116/profmed20252802196
Loss of CTRP10 results in female obesity with preserved metabolic healthPreprint
Chen, F., Sarver, D. C., Saqib, M., Vélez, L. M., Aja, S. M., Seldin, M. M., & Wong, G. W. (2025) · eLife · doi:10.7554/elife.93373.2
Wafer, R., Tandon, P., & Minchin, J. E. N. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.20.649706
Cota, C. C., Miranda-Castro, S., Souza-Gomes, A. F., Leite, L. B., Forte, P. M., Monteiro, A. M., Pereira, W. V. C., de Moura, S. S., & Nunes-Silva, A. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14124170 · Cited by 1
Wafer, R., Tandon, P., & Minchin, J. E. N. (2025) · eLife · doi:10.7554/elife.107327.1
Hydrogels for adipose tissue engineering
Babu, S., Anthraper, M. S. J., Ramu, J., Rajendran, A. K., & Jayakumar, R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-29260-6.00007-x
Paul, F., Wang, H., Wang, J., Tan, L. J., Chia, C. Y., Sun, L., Goh, H. J., Kelly, M., Sadananthan, S. A., Narayanan, G., et al. (2025) · medRxiv · doi:10.1101/2025.07.28.25332029
Mediated amperometric monitoring of redox changes during adipocyte differentiation
Saunier, V., Volat, F., Gironde, C., Chaput, B., Renaud, L., Bouloumié, A., & Bergel, A. (2026) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2026.109484
Fronczek, M., Banach, M., Goławski, M., & Osadnik, T. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-27333-9.00013-0
Impact of Stress on Hormonal Imbalance in Rats with Alimentary Obesity
Shotaev, V. V., Doshkhokloeva, K. R., Vakhidova, P. H.-A., Dudkin, R. A., Kostiukova, D. Y., Ionova, S. M., Burzhunova, M. K., & Tsybulina, A. V. (2024) · International Journal of Social and Psychological Aspects of Healthcare · doi:10.51847/ibeauqnjrs
Zhang, S., Zhang, Z., Xiao, Y., Chen, M., Hu, L., Tang, H., Liao, L., & Li, X. (2025) · Critical Public Health · doi:10.1080/09581596.2025.2571874
Association of Body Composition with Insulin Resistance in a Middle-Aged Population
Zhou, K., Zhang, Y., Chen, M., Deng, Q., Kang, H., Li, K., Wu, Y., Zhang, J., Zhu, J., Zheng, T., et al. (2025) · Hormone and Metabolic Research · doi:10.1055/a-2691-0442
Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction
Jousma, J., Han, Z., Park, J., Yan, G., Zhang, S., Kwon, Y., Nukala, S. B., Kandola, J., Pinho, S., Liew, C. W., et al. (2025) · Advanced Science · doi:10.1002/advs.202506106 · Cited by 1
Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model
Zhang, Q., Wang, Y., Zhang, H., Xu, G., Xu, S., & Yang, G. (2025) · Integrative Zoology · doi:10.1111/1749-4877.70047
Zhu, L., Feng, Z., Shu, X., Gao, Q., Wu, J., Du, Z., Li, R., Wang, L., Chen, N., Li, Y., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14992783
Kittichaiworakul, R., Thongkumkoon, P., Vaddhanaphuti, C. S., Rojanaverawong, W., Sutheeworapong, S., Wongpoomchai, R., & Dissook, S. (2026) · Nutrients · doi:10.3390/nu18162667
Abudujilile, D., Wang, W., Aimaier, A., Chang, L., Dong, Y., Wang, Y., Fan, X., Ma, Y., Wang, Y., Ziyayiding, D., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21332744
Zhu, L., Feng, Z., Shu, X., Gao, Q., Wu, J., Du, Z., Li, R., Wang, L., Chen, N., Li, Y., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14992780
Abudujilile, D., Wang, W., Aimaier, A., Chang, L., Dong, Y., Wang, Y., Fan, X., Ma, Y., Wang, Y., Ziyayiding, D., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21332741
Additional file 2 of Slc25a5 regulates adipogenesis by modulating ERK signaling in OP9 cells
Zhu, S., Wang, W., Zhang, J., Ji, S., Jing, Z., & Chen, Y. Q. (2022) · Figshare · doi:10.6084/m9.figshare.19112731
Additional file 1 of Slc25a5 regulates adipogenesis by modulating ERK signaling in OP9 cells
Zhu, S., Wang, W., Zhang, J., Ji, S., Jing, Z., & Chen, Y. Q. (2022) · Figshare · doi:10.6084/m9.figshare.19112728
Han, X., Li, W., He, X., Lu, X., Zhang, Y. F., Li, Y., Bi, G., Ma, X., Huang, X., Bai, R., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26624554
Han, X., Li, W., He, X., Lu, X., Zhang, Y. F., Li, Y., Bi, G., Ma, X., Huang, X., Bai, R., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26624557
Yao, T., Wei, D., Tian, X., Zhao, L., Wan, Q., Zhang, X., Cai, J., Li, S., Diao, B., Feng, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25449015
Zhou, J., Zhang, S., Teng, Y., Lu, J., Guo, Y., Yan, S., Tao, F., & Huang, K. (2023) · Figshare · doi:10.6084/m9.figshare.23208021
Braud, L., Ninni, A., Miranda, A. M. A., Baudelet, É., Vernerey, J., Villaverde, M., Sciarretta, F., Bernabe, M., Girondier, L., Elia, I., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.18.694395
Thomas, N. S., Sankofi, B. M., Cen, H. H., Sekhri, M., Murguia, S. J., Cherian, M. A., Stout, M. B., Miller, B. F., Rudolph, M. C., & Wellberg, E. A. (2026) · Communications Biology · doi:10.64898/2025.12.21.695772
Overweight worsens the metabolic presentation of type 1 diabetes mellitus in children
Muzslay, E., Herczeg, V., Pusztai, R. I., Forstreuter, V. Z., Soós, D., Takács, J., Tóth‐Heyn, P., & Luczay, A. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1740046
Sysoeva, V., Arbatskiy, M. S., Kulebyakin, K. Y., Tyurin‐Kuzmin, P. A., Semina, E. V., Сергеевна, К. П., Brodsky, I. B., Romashin, D. D., Altyeva, A. F., Сергеевич, В. Н., et al. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1734183
Wang, Y., Zhu, L., Yang, Y., You, Z., Peng, Z., Yang, S., Lu, Y., Zhao, Y., Kong, Y., Wan, Q., et al. (2026) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfag006
Camon, C., Kip, E., Lord, R. A., Decourt, C., Prescott, M., Clarkson, J., Prókai-Tátrai, K., Correa, S. M., Campbell, R. E., & Garratt, M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.26.701850
So, J., Wann, J., Kim, K., Taleb, S., Kim, H.-G., Kumari, M., Banks, A. S., Dong, X. C., & Roh, H. C. (2026) · Metabolism · doi:10.1016/j.metabol.2026.156548
Nan, B., Pan, K., Xu, C., Zhao, J., & Zhang, J. (2026) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2026.119896
Hwang, J., Choi, H., & Kim, H. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.108515
Yu, X., Li, Y., Feng, Y., Cheng, Z., Sun, B., & Cai, X.-R. (2026) · Abdominal Radiology · doi:10.1007/s00261-026-05449-6
Metadata
- Authors
- Vishvanath, L., & Gupta, R. K.
- Affiliations
- The University of Texas at Dallas (US)
- Touchstone (China) (CN)
- Corresponding author
- Gupta, Rana K.
- Venue
- Journal of Clinical Investigation
- Published
- 2019-10-01
- Volume
- 129
- Issue
- 10
- Pages
- 4022-4031
- ISSN
- 0021-9738 (ISSN-L)
- 1558-8238
- PMC
- PMC6763245
- OpenAlex
- W2978642359
- Cited by
- 558
- References
- 98
- Citations by year
- 2026: 77 · 2025: 72 · 2024: 89 · 2023: 92 · 2022: 98 · 2021: 85 · 2020: 43 · 2019: 2
- FWCI
- 8.39
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK119163, R56DK119163)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- adipogenesis, obesity, metabolically healthy obesity, adipose tissue remodeling, visceral adipose tissue, subcutaneous adipose tissue, insulin resistance, adipocyte hypertrophy, adipose tissue inflammation, adipose tissue fibrosis, adipose-derived stem cells, single-cell RNA sequencing
- MeSH terms
- RNA-Seq, Animals, Energy Metabolism, Humans, Insulin Resistance, Obesity, Risk Factors, Stem Cells, Metabolic Syndrome, Adipogenesis, Mice, Adipose Tissue, White, Adipocytes, White, Single-Cell Analysis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review