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Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia

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Beetroot, A Remarkable Vegetable: Its Nitrate and Phytochemical Contents Can be Adjusted in Novel Formulations to Benefit Health and Support Cardiovascular Disease Therapies

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Hydrogen Sulfide: Recent Progression and Perspectives for the Treatment of Diabetic Nephropathy

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Cancer-derived extracellular succinate: a driver of cancer metastasis

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Metabolite-Sensing G Protein-Coupled Receptors Connect the Diet-Microbiota-Metabolites Axis to Inflammatory Bowel Disease

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Obesity and Diabetic Kidney Disease: Role of Oxidant Stress and Redox Balance

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Gut microbiota and renin-angiotensin system: a complex interplay at local and systemic levels

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High glucose and renin release: the role of succinate and GPR91

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The evolving story of the RAAS in hypertension, diabetes and CV disease – moving from macrovascular to microvascular targets

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Activation of the renal renin-angiotensin system in diabetes--new concepts

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Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells

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Succinate Receptor 1: An Emerging Regulator of Myeloid Cell Function in Inflammation

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The role of the GPR91 ligand succinate in hematopoiesis

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Succinate modulates Ca2+ transient and cardiomyocyte viability through PKA-dependent pathway

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Unsuspected task for an old team: Succinate, fumarate and other Krebs cycle acids in metabolic remodeling

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Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression

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The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis

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Hypertension: The role of biochemistry in the diagnosis and management

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Big science and big data in nephrology

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Discovery of a potent and selective small molecule hGPR91 antagonist

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Redox Activation of Mitochondrial DAMPs and the Metabolic Consequences for Development of Autoimmunity

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Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of T h 17 cells in the lymph nodes

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α-Ketoglutarate regulates acid-base balance through an intrarenal paracrine mechanism

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Pharmacological targets of metabolism in disease: Opportunities from macrophages

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Postbiotic Impact on Host Metabolism and Immunity Provides Therapeutic Potential in Metabolic Disease

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Direct Activation of ENaC by Angiotensin II: Recent Advances and New Insights

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Novel in vivo techniques to visualize kidney anatomy and function

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A New Look at Electrolyte Transport in the Distal Tubule

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The glomerulus – a view from the inside – the endothelial cell

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ERK1/2/COX-2/PGE2 signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes.

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Identification and pharmacological characterization of succinate receptor agonists

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The first decade of using multiphoton microscopy for high-power kidney imaging

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The ocular renin–angiotensin system: A therapeutic target for the treatment of ocular disease

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Maintenance of Homeostasis in the Aging Hypothalamus: The Central and Peripheral Roles of Succinate

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Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats

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Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

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Oxidative Stress and Cardiovascular Complications in Chronic Kidney Disease, the Impact of Anaemia

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Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells

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Involvement of the metabolic sensor GPR81 in cardiovascular control

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Chinese herbal drugs for the treatment of diabetic retinopathy

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Activation of HIF-1α (hypoxia inducible factor-1α) prevents dry eye-induced acinar cell death in the lacrimal gland

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Multiphoton Imaging of Renal Regulatory Mechanisms

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Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development

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Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3‐kinase‐β signaling

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Expression and Iron-Dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium

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Succinate receptor GPR91, a Gα i coupled receptor that increases intracellular calcium concentrations through PLCβ

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Forskolin-free cAMP assay for Gi-coupled receptors

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Succinate Dehydrogenase and Ribonucleic Acid Networks in Cancer and Other Diseases

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GPCRs involved in metabolic diseases: pharmacotherapeutic development updates

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Pulmonary Pathogens Adapt to Immune Signaling Metabolites in the Airway

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High glucose and renin release: the role of succinate and GPR91

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Succinate activates the collecting duct renin‐angiotensin system (RAS)

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Metabolic control of renin secretion

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Macula densa cells detect altered tissue metabolism via succinate and GPR91

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