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Cited by 240

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Insight into the heterogeneity of breast cancer through next-generation sequencing

Open access
Russnes, Hege G., Navin, Nicholas, Hicks, James, Borresen-Dale, Anne-Lise·2011·Journal of Clinical Investigation

Abstract

Rapid and sophisticated improvements in molecular analysis have allowed us to sequence whole human genomes as well as cancer genomes, and the findings suggest that we may be approaching the ability to individualize the diagnosis and treatment of cancer. This paradigmatic shift in approach will require clinicians and researchers to overcome several challenges including the huge spectrum of tumor types within a given cancer, as well as the cell-to-cell variations observed within tumors. This review discusses how next-generation sequencing of breast cancer genomes already reveals insight into tumor heterogeneity and how it can contribute to future breast cancer classification and management.

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Crossref · 10.1172/jci57088

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Metadata

Authors
Russnes, H. G., Navin, N., Hicks, J., & Borresen-Dale, A.-L.
Venue
Journal of Clinical Investigation
Published
2011-10-03
Volume
121
Issue
10
Pages
3810-3818
ISSN
0021-9738 (ISSN-L)
OpenAlex
W1964302896
Cited by
240
References
5
FWCI
7.85
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Insight into the heterogeneity of breast cancer through next-generation sequencing. https://app.cochat.ai/papers/10.1172/jci57088
The paper
Russnes, H. G., Navin, N., Hicks, J., & Borresen-Dale, A.-L. (2011). Insight into the heterogeneity of breast cancer through next-generation sequencing. Journal of Clinical Investigation. https://doi.org/10.1172/jci57088

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.