The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
A role for NF-κB–dependent gene transactivation in sunburn
Open accessAbstract
Exposure of skin to ultraviolet (UV) radiation is known to induce NF-kappaB activation, but the functional role for this pathway in UV-induced cutaneous inflammation remains uncertain. In this study, we examined whether experimentally induced sunburn reactions in mice could be prevented by blocking UV-induced, NF-kappaB-dependent gene transactivation with oligodeoxynucleotides (ODNs) containing the NF-kappaB cis element (NF-kappaB decoy ODNs). UV-induced secretion of IL-1, IL-6, TNF-alpha, and VEGF by skin-derived cell lines was inhibited by the decoy ODNs, but not by the scrambled control ODNs. Systemic or local injection of NF-kappaB decoy ODNs also inhibited cutaneous swelling responses to UV irradiation. Moreover, local UV-induced inflammatory changes (swelling, leukocyte infiltration, epidermal hyperplasia, and accumulation of proinflammatory cytokines) were all inhibited specifically by topically applied decoy ODNs. Importantly, these ODNs had no effect on alternative types of cutaneous inflammation caused by irritant or allergic chemicals. These results indicate that sunburn reactions culminate from inflammatory events that are triggered by UV-activated transcription of NF-kappaB target genes, rather than from nonspecific changes associated with tissue damage.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“However, it is likely that the photoprotective activity of vitamin D compounds includes a reduction in skin inflammation, which plays a crucial role in sunburn formation [104].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases
Barnes, P. J., & Karin, M. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704103361506 · Cited by 4,622
CpG motifs in bacterial DNA trigger direct B-cell activation
Krieg, A. M., Yi, A.-K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A., & Klinman, D. M. (1995) · Nature · doi:10.1038/374546a0 · Cited by 3,508
Dérijard, B., Hibi, M., Wu, I.-H., Barrett, T., Su, B., Deng, T., Karin, M., & Davis, R. J. (1994) · Cell · doi:10.1016/0092-8674(94)90380-8 · Cited by 3,188
Baeuerle, P. A., & Baltimore, D. (1996) · Cell · doi:10.1016/s0092-8674(00)81318-5 · Cited by 3,002
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
Yin, M.-J., Yamamoto, Y., & Gaynor, R. B. (1998) · Nature · doi:10.1038/23948 · Cited by 1,596
Rosette, C., & Karin, M. (1996) · Science · doi:10.1126/science.274.5290.1194 · Cited by 1,034
Kasibhatla, S., Brunner, T., Genestier, L., Echeverri, F., Mahboubi, A., & Green, D. R. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80054-4 · Cited by 721
Köck, A., Schwarz, T., Kirnbauer, R., Urbanski, A., Perry, P., Ansel, J. C., & Luger, T. A. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.172.6.1609 · Cited by 712
Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway
Lee, F. S., Hagler, J., Chen, Z. J., & Maniatis, T. (1997) · Cell · doi:10.1016/s0092-8674(00)81842-5 · Cited by 710
CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells
Hartmann, G., Weiner, G. J., & KRIEG, A. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.9305 · Cited by 623
Research works printed but not linked: 2
- Scharffetter-Kochanek, 1997, Biol Chem, 378, 1247
- Yuspa, 1980, Cancer Res, 40, 4694
Cited by
Sorted by citations
Aggarwal, B. B., Vijayalekshmi, R. V., & Sung, B. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-0149 · Cited by 812
Pillai, S., Oresajo, C., & Hayward, J. (2005) · International Journal of Cosmetic Science · doi:10.1111/j.1467-2494.2004.00241.x · Cited by 706
Photoaging: mechanisms and repair
Rabe, J. H., Mamelak, A. J., McElgunn, P. J. S., Morison, W. L., & Sauder, D. N. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2005.05.010 · Cited by 610
Ultraviolet light induced injury: Immunological and inflammatory effects
Clydesdale, G. J., Dandie, G. W., & Muller, H. K. (2001) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.2001.01047.x · Cited by 590
Huang, S., Pettaway, C. A., Uehara, H., Bucana, C. D., & Fidler, I. J. (2001) · Oncogene · doi:10.1038/sj.onc.1204535 · Cited by 556
Abeyama, K., Stern, D. M., Ito, Y., Kawahara, K., Yoshimoto, Y., Tanaka, M., Uchimura, T., Ida, N., Yamazaki, Y., Yamada, S., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci22782 · Cited by 547
Self-citationNuclear factor-kappa B and cancer: its role in prevention and therapy
Bharti, A. C., & Aggarwal, B. B. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01154-1 · Cited by 516
Mizumoto, N., Kumamoto, T., Robson, S. C., Sévigny, J., Matsue, H., Enjyoji, K., & Takashima, A. (2002) · Nature Medicine · doi:10.1038/nm0402-358 · Cited by 327
Self-citationPhotochemoprevention of ultraviolet B signaling and photocarcinogenesis
Afaq, F., Adhami, V. M., & Mukhtar, H. (2005) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.07.019 · Cited by 319
Emdad, L., Sarkar, D., Su, Z.-Z., Randolph, A. L., Boukerche, H., Valerie, K. C., & Fisher, P. B. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3029 · Cited by 279
The Pathogenesis of Pterygium: Current Concepts and Their Therapeutic Implications
Chui, J. J. Y., Girolamo, N. D., Wakefield, D., & Coroneo, M. T. (2008) · The Ocular Surface · doi:10.1016/s1542-0124(12)70103-9 · Cited by 279
The UV response of the skin: a review of the MAPK, NFκB and TNFα signal transduction pathways
Muthusamy, V., & Piva, T. J. (2010) · Archives of Dermatological Research · doi:10.1007/s00403-009-0994-y · Cited by 265
Maverakis, E., Miyamura, Y., Bowen, M. P., Correa, G., Ono, Y., & Goodarzi, H. (2009) · Journal of Autoimmunity · doi:10.1016/j.jaut.2009.11.011 · Cited by 267
Kiriakidis, S., Andreakos, E., Monaco, C. G., Foxwell, B. M. J., Feldmann, M., & Paleolog, E. M. (2003) · Journal of Cell Science · doi:10.1242/jcs.00286 · Cited by 245
TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN INFLAMMATION
Kracht, M., & Saklatvala, J. (2002) · Cytokine · doi:10.1006/cyto.2002.0895 · Cited by 229
Cooper, S., & Bowden, G. T. (2007) · Current Cancer Drug Targets · doi:10.2174/156800907780809714 · Cited by 208
Chamcheu, J. C., Roy, T., Uddin, M. B., Banang‐Mbeumi, S., Chamcheu, R. N., Walker, A. L., Liu, Y., & Huang, S. (2019) · Cells · doi:10.3390/cells8080803 · Cited by 212
Nutraceuticals for Skin Care: A Comprehensive Review of Human Clinical Studies
Pérez-Sánchez, A., Barrajón‐Catalán, E., Herranz‐López, M., & Micol, V. (2018) · Nutrients · doi:10.3390/nu10040403 · Cited by 194
Involvement of NF-κB signalling in skin physiology and disease
Bell, S. A., Degitz, K., Quirling, M., Jilg, N., Page, S., & Brand, K. (2003) · Cellular Signalling · doi:10.1016/s0898-6568(02)00080-3 · Cited by 173
Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking
Mummert, M. E., Mohamadzadeh, M., Mummert, D. I., Mizumoto, N., & Takashima, A. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.6.769 · Cited by 166
Self-citationLópez-Camarillo, C., Aréchaga Ocampo, E., López Casamichana, M., Pérez-Plasencia, C., Álvarez-Sánchez, E., & Marchat, L. A. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms13010142 · Cited by 165
Roy, T., Boateng, S. T., Uddin, M. B., Banang‐Mbeumi, S., Yadav, R. K., Bock, C. R., Folahan, J. T., Siwe‐Noundou, X., Walker, A. L., King, J. A. C., et al. (2023) · Cells · doi:10.3390/cells12121671 · Cited by 182
Scheinman, P. L., Vocanson, M., Thyssen, J. P., Johansen, J. D., Nixon, R. L., Dear, K., Botto, N. C., Morot, J., & Goldminz, A. M. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-021-00271-4 · Cited by 174
Chaiprasongsuk, A., Janjetovic, Z., Kim, T.-K., Jarrett, S. G., D'Orazio, J. A., Holick, M. F., Tang, E. K. Y., Tuckey, R. C., Panich, U., Li, W., et al. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101206 · Cited by 146
Desmet, C. J., Gosset, P., Pajak, B., Cataldo, D. D., Bentires‐Alj, M., Lekeux, P. M., & Bureau, F. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.9.5766 · Cited by 137
Sand, J., Haertel, E., Biedermann, T., Contassot, E., Ernst Reichmann, A., French, L. E., Werner, S., & Beer, H. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0009-4 · Cited by 132
Hamada, T., Torikai, M., Kuwazuru, A., Tanaka, M., Horai, N., Fukuda, T., Yamada, S., Nagayama, S., Hashiguchi, K., Sunahara, N., et al. (2008) · Arthritis & Rheumatism · doi:10.1002/art.23729 · Cited by 130
Self-citationHinata, K., Gervin, A. M., Zhang, J. Y., & Khavari, P. A. (2003) · Oncogene · doi:10.1038/sj.onc.1206198 · Cited by 130
Biological consequences of cyclobutane pyrimidine dimers
Vink, A. A., & Roza, L. (2001) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/s1011-1344(01)00245-7 · Cited by 122
Self-citationGreul, A., Grundmann, J., Heinrich, F., Pfitzner, I., Bernhardt, J. H., Ambach, A., Biesalski, H. K., & Gollnick, H. P. M. (2002) · Skin Pharmacology and Physiology · doi:10.1159/000064534 · Cited by 124
Ichihashi, M., Ando, H., Yoshida, M., Niki, Y., & Matsui, M. S. (2009) · Anti-aging Medicine · doi:10.3793/jaam.6.46 · Cited by 123
Levine, L., Lucci, J. A., Pazdrak, B., Cheng, J. Z., Guo, Y., Townsend, C. M., & Hellmich, M. R. (2003) · PubMed · Cited by 122
Nuclear factor kappa B—molecular biomedicine: the next generation
Celec, P. (2004) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2003.12.015 · Cited by 113
NF‐κB activity blockade impairs the angiogenic potential of human pancreatic cancer cells
Xiong, H. Q., Abbruzzese, J. L., Lin, E. H., Wang, L., Zheng, L., & Xie, K. (2003) · International Journal of Cancer · doi:10.1002/ijc.11562 · Cited by 110
Skin cancer: role of ultraviolet radiation in carcinogenesis
Mancebo, S. E., & Wang, S. Q. (2014) · Reviews on Environmental Health · doi:10.1515/reveh-2014-0041 · Cited by 108
Prostaglandin E2 is required for ultraviolet B-induced skin inflammation via EP2 and EP4 receptors
Kabashima, K., Nagamachi, M., Honda, T., Nishigori, C., Miyachi, Y., TOKURA, Y., & Narumiya, S. (2006) · Laboratory Investigation · doi:10.1038/labinvest.3700491 · Cited by 99
Tanaka, K., Hasegawa, J., Asamitsu, K., & Okamoto, T. (2005) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.088674 · Cited by 96
Supreme EnLIGHTenment: Damage Recognition and Signaling in the Mammalian UV Response
Herrlich, P. A., Karin, M., & Weiß, C. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.01.001 · Cited by 94
Hair follicles serve as local reservoirs of skin mast cell precursors
Kumamoto, T., Shalhevet, D., Matsue, H., Mummert, M. E., Ward, B. R., Jester, J. V., & Takashima, A. (2003) · Blood · doi:10.1182/blood-2003-02-0449 · Cited by 93
Self-citationLennikov, A., Mirabelli, P., Mukwaya, A., Schaupper, M., Thangavelu, M., Lachota, M., Ali, Z., Jensen, L. D., & Lagali, N. (2018) · Angiogenesis · doi:10.1007/s10456-018-9594-9 · Cited by 88
Hildesheim, J., Awwad, R. T., & Fornace, A. J. (2004) · Journal of Investigative Dermatology · doi:10.1111/j.1523-1747.2004.22229.x · Cited by 90
Gao, W., Wang, Y., Hwang, E., Lin, P., Bae, J., Seo, S. A., Yan, Z., & Yi, T. (2018) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2018.06.007 · Cited by 89
Molecular imaging of the transcription factor NF-κB, a primary regulator of stress response
Carlsen, H., Alexander, G., Austenaa, L. M. I., Ebihara, K., & Blomhoff, R. (2004) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.02.024 · Cited by 79
Lu, J., Guo, J.-H., Tu, X.-L., Zhang, C., Zhao, M., Zhang, Q.-W., & Gao, F.-H. (2016) · PLOS ONE · doi:10.1371/journal.pone.0159998 · Cited by 79
Keratinocytes in epidermal immune responses
Steinhoff, M. S., Brzoska, T., & Luger, T. A. (2001) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/01.all.0000011062.60720.e3 · Cited by 79
Martin, K., Müller, P., Schreiner, J., Prince, S. S., Lardinois, D., Heinzelmann-Schwarz, V. A., Thommen, D. S., & Zippelius, A. (2014) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-014-1565-4 · Cited by 78
Molecular changes during skin aging and wound healing after fractional ablative photothermolysis
Helbig, D., & Paasch, U. (2011) · Skin Research and Technology · doi:10.1111/j.1600-0846.2010.00477.x · Cited by 77
Li, B., Chen, M., Liu, X., & Guo, S. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.04.028 · Cited by 78
Bou-Dargham, M. J., Khamis, Z. I., Cognetta, A. B., & Sang, Q. A. (2016) · Medicinal Research Reviews · doi:10.1002/med.21406 · Cited by 76
The protective effect of 18β-Glycyrrhetinic acid against UV irradiation induced photoaging in mice
Kong, S.-Z., Chen, H.-M., Yu, X.-T., Zhang, X., Feng, X.-X., Kang, X.-H., Li, W.-J., Huang, N., Luo, H., & Su, Z.-R. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2014.12.008 · Cited by 73
Garg, C., Sharma, H., & Garg, M. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101127 · Cited by 70
Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells
Farahani, M., Treweeke, A. T., Toh, C., Till, K. J., Harris, R. J., Cawley, J. C., Zuzel, M., & Chen, H. (2005) · Leukemia · doi:10.1038/sj.leu.2403631 · Cited by 70
Co-activation of ERK, NF-κB, and GADD45β in Response to Ionizing Radiation
Wang, T., Hu, Y., Dong, S., Fan, M., Tamae, D., Ozeki, M., Gao, Q., Gius, D. R., & Li, J. J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m410982200 · Cited by 64
Pterygium—The Good, the Bad, and the Ugly
Acker, S. I. V., den Bogerd, B. V., Haagdorens, M. K. C., Siozopoulou, V., Dhubhghaill, S. N., Pintelon, I., & Koppen, C. (2021) · Cells · doi:10.3390/cells10071567 · Cited by 66
Johansen, C., Riis, J. L., Gedebjerg, A., Kragballe, K., & Iversen, L. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.240671 · Cited by 67
Seo, K. H., Lee, H.-S., Jung, B., Ko, H.-M., Choi, J., Park, S. J., Choi, I.-H., Lee, H.-K., & Im, S. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-2774 · Cited by 61
Karthikeyan, R., Kanimozhi, G., Prasad, N. R., Balupillai, A., Muthusamy, G., Shanmugham, M., & Gunaseelan, S. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.04.027 · Cited by 61
Calniquer, G., Khanin, M., Ovadia, H., Linnewiel‐Hermoni, K., Stepensky, D., Trachtenberg, A., Sedlov, T., Braverman, O., Levy, J., & Sharoni, Y. (2021) · Molecules · doi:10.3390/molecules26071931 · Cited by 61
Practical and experimental consideration of sun protection in dermatology
Ting, W. W., Vest, C. D., & Sontheimer, R. D. (2003) · International Journal of Dermatology · doi:10.1046/j.1365-4362.2003.01867.x · Cited by 58
Shanmugam, R., Jayaprakasan, V., Gökmen‐Polar, Y., Kelich, S. L., Miller, K. D., Yip-Schneider, M., Liang Cheng, C., Bhat‐Nakshatri, P., Sledge, G. W., Nakshatri, H., et al. (2006) · The Prostate · doi:10.1002/pros.20482 · Cited by 56
Epigenetics changes associated to environmental triggers in autoimmunity
Cañas, C. A., Cañas, F., Bonilla‐Abadía, F., Ospina, F. E., & Tobón, G. J. (2015) · Autoimmunity · doi:10.3109/08916934.2015.1086996 · Cited by 49
The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair
Ramnath, D., Powell, E. E., Scholz, G. M., & Sweet, M. J. (2016) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2016.08.014 · Cited by 49
The Nuclear-Factor κB Pathway Is Activated in Pterygium
Siak, J. J. K., Ng, S. L., Seet, L., Beuerman, R. W., & Tong, L. H. T. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-5735 · Cited by 48
Thatcher, T. H., Luzina, I. G., Fishelevich, R., Tomai, M. A., Miller, R. L., & Gaspari, A. A. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700167 · Cited by 47
Lee, J., Ko, S.-H., Ye, S., & Chung, M.-H. (2013) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2013.01.010 · Cited by 46
Short-chain aldehyde-derived ligands for RAGE and their actions on endothelial cells
Yamamoto, Y., Yonekura, H., Watanabe, T., Sakurai, S., Li, H., Harashima, A., Myint, K. M., Osawa, M., Takeuchi, A., Takeuchi, M., et al. (2007) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2007.01.030 · Cited by 44
Lee, S.-J., Lee, K. B., Son, Y. H., Shin, J., Lee, J.-H., Kim, H.-J., Hong, A.-Y., Bae, H. W., Kwon, M.-A., Lee, W. J., et al. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.550 · Cited by 44
HMGB‐1 induces IL‐6 production in human synovial fibroblasts through c‐Src, Akt and NF‐κB pathways
Hou, C., Fong, Y., & Tang, C. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22541 · Cited by 42
Ting, W. W., & Sontheimer, R. D. (2001) · Lupus · doi:10.1191/096120301667674688 · Cited by 41
Seo, K. H., Ko, H., Choi, J. H., Jung, H. H., Chun, Y. H., Choi, I., Lee, H., & Im, S. (2004) · European Journal of Immunology · doi:10.1002/eji.200424957 · Cited by 39
Xeroderma Pigmentosum: General Aspects and Management
Piccione, M., Fortina, A. B., Ferri, G., Andolina, G., Beretta, L., Cividini, A., Marni, E. D., Caroppo, F., Citernesi, U., & Liddo, R. D. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11111146 · Cited by 45
Torres, J., Enríquez‐de‐Salamanca, A., Fernández, I., Ares, M. T. R., Quadrado, M. J., Murta, J., del Castillo, J. M. B., Stern, M. E., & Calonge, M. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6673 · Cited by 36
UV induces VEGF through a TNF‐α‐independent pathway
Kosmadaki, M. G., Yaar, M., Arble, B. L., & Gilchrest, B. A. (2003) · The FASEB Journal · doi:10.1096/fj.02-0379fje · Cited by 36
HMGB-1 induces cell motility and α5β1 integrin expression in human chondrosarcoma cells
Tang, C., Keng, Y.-T., & Liu, J. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.02.014 · Cited by 33
Kim, H. N., Gil, C. H., Kim, Y. R., Shin, H. K., & Choi, B. T. (2016) · Scientific Reports · doi:10.1038/srep31169 · Cited by 34
Lee, S., Lee, E. J., Lee, G. M., Yun, J.-H., & Yoo, W. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1162934 · Cited by 32
McGee, H. M., Woods, G. M., Bennett, B., & Chung, R. S. (2010) · Photochemical & Photobiological Sciences · doi:10.1039/b9pp00155g · Cited by 31
Topical Administration of Manuka Oil Prevents UV-B Irradiation-Induced Cutaneous Photoaging in Mice
Kwon, O. S., Jung, S. H., & Yang, B. S. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/930857 · Cited by 32
The NLRP1 Inflammasome Pathway Is Silenced in Cutaneous Squamous Cell Carcinoma
Sand, J., Fenini, G., Grossi, S., Hennig, P., Filippo, M. D., Levesque, M. P., Werner, S., French, L. E., & Beer, H. (2019) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.01.025 · Cited by 29
Potential Photoprotective Effect of Dietary Corn Silk Extract on Ultraviolet B-Induced Skin Damage
Kim, Y.-H., Cho, A., Kwon, S.-A., Kim, M., Song, M., Han, H. W., Shin, E.-J., Park, E., & Lee, S.-M. (2019) · Molecules · doi:10.3390/molecules24142587 · Cited by 32
Yokozeki, H., Wu, M., Sumi, K., Awad, S., Satoh, T., Katayama, I., Takeda, K., Akira, S., Kaneda, Y., & Nishioka, K. (2004) · Gene Therapy · doi:10.1038/sj.gt.3302341 · Cited by 30
Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABAA partial agonist, in humans
van Amerongen, G., Siebenga, P. S., Gurrell, R., Dua, P., Whitlock, M., Gorman, D. N., Okkerse, P., Hay, J. L., Butt, R. P., & Groeneveld, G. J. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.12.006 · Cited by 30
Xu, M. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i16.2361 · Cited by 30
Zhang, J., Song, H., Lu, Y., Chen, H., Jiang, S., & Li, L. (2016) · Oncology Reports · doi:10.3892/or.2016.4888 · Cited by 29
The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes
Hogan, K. A., Ravindran, A., Podolsky, M. A., & Glick, A. B. (2013) · Cytokine · doi:10.1016/j.cyto.2013.09.004 · Cited by 29
Morinda citrifolia Linn. (Rubiaceae) leaf extracts mitigate UVB-induced erythema
West, B. J., Deng, S., Palu, '. K., & Jensen, C. J. (2009) · Journal of Natural Medicines · doi:10.1007/s11418-009-0327-7 · Cited by 29
Involvement of hyaluronan in epidermal Langerhans cell maturation and migration in vivo
Mummert, D. I., Takashima, A., Ellinger, L., & Mummert, M. E. (2003) · Journal of Dermatological Science · doi:10.1016/s0923-1811(03)00160-9 · Cited by 29
Self-citationGarcía‐Pérez, M., Allaeys, I., Rusu, D., Pouliot, R., Janežić, T. S., & Poubelle, P. E. (2013) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2013.10.034 · Cited by 28
Influence of GSTT1 and GSTM1 Genotypes on Sunburn Sensitivity
Kerb, R., BROCKMOLLER, J., Schlagenhaufer, R., Sprenger, R., Roots, I., & Brinkmann, U. (2002) · American Journal of PharmacoGenomics · doi:10.2165/00129785-200202020-00007 · Cited by 27
Kim, Y. H., Chung, I. Y., Choi, M., Kim, Y. S., Lee, J. H., Park, C. H., Kang, S. S., Roh, G. S., Choi, W. S., Yoo, J. M., et al. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.02.002 · Cited by 26
Kinose, Y., Sawada, K., Makino, H., Ogura, T., Mizuno, T., Suzuki, N., Fujikawa, T., Morii, E., Nakamura, K., Sawada, I., et al. (2015) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-14-0696 · Cited by 26
Modeling of solar UV-induced photodamage on the hair follicles in human skin organoids
Kim, M.-J., Ahn, H.-J., Kong, D., Lee, S., Kim, D.-H., & Kang, K.-S. (2024) · Journal of Tissue Engineering · doi:10.1177/20417314241248753 · Cited by 25
Alexander, G., Carlsen, H., & Blomhoff, R. (2005) · Experimental Eye Research · doi:10.1016/j.exer.2005.09.012 · Cited by 24
Receptors in Skin Ageing and Antiageing Agents
Ghersetich, I., Troiano, M., GIORGI, V. D., & Lotti, T. (2007) · Dermatologic Clinics · doi:10.1016/j.det.2007.06.018 · Cited by 24
Mechanism by which H-2g, a glucose analog of blood group H antigen, mediates angiogenesis
Zhu, K., Amin, M. A., Zha, Y., Harlow, L. A., & Koch, A. E. (2004) · Blood · doi:10.1182/blood-2004-08-3140 · Cited by 24
Kulms, D., & Schwarz, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006372200 · Cited by 24
Xu, M. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i44.6960 · Cited by 23
Myotrophin–κB DNA interaction in the initiation process of cardiac hypertrophy
Gupta, S., & Sen, S. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(02)00178-7 · Cited by 23
Kim, Y. J., Kim, H.-N., Shin, M., & Choi, B. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/539172 · Cited by 22
Guo, M., Lu, Y., Yang, J.-P., Zhao, X., & Lü, Y. (2016) · Pharmaceutical Biology · doi:10.1080/13880209.2016.1199041 · Cited by 23
Metadata
- Authors
- Abeyama, K., Eng, W., Jester, J. V., Vink, A. A., Edelbaum, D., Cockerell, C. J., Bergstresser, P. R., & Takashima, A.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- Netherlands Organisation for Applied Scientific Research (NL)
- Corresponding author
- Takashima, Akira
- Venue
- Journal of Clinical Investigation
- Published
- 2000-06-15
- Volume
- 105
- Issue
- 12
- Pages
- 1751-1759
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC378515
- OpenAlex
- W2136200385
- Cited by
- 160
- References
- 66
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 4 · 2023: 3 · 2022: 3 · 2021: 9 · 2020: 1 · 2019: 7 · 2018: 7 · 2017: 1 · 2016: 11 · 2015: 3 · 2014: 3 · 2013: 5 · 2012: 3
- FWCI
- 4.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01 AR 35068, R01-AR40042, R01-AR43777, R01AR040042, R01AR043777, R01AR035068)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › NF-κB Signaling Pathways
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Keywords
- NF-κB, sunburn, ultraviolet radiation, skin inflammation, decoy oligonucleotides, gene transactivation, inflammatory cytokines, interleukin-1, interleukin-6, TNF-α, vascular endothelial growth factor, epidermal hyperplasia, leukocyte infiltration, topical gene therapy
- MeSH terms
- Animals, Base Sequence, Cell Line, Edema, Female, Gene Expression Regulation, Hyperplasia, Langerhans Cells, Mice, Inbred A, Mice, Inbred BALB C, Oligodeoxyribonucleotides, Skin, Sunburn, Ultraviolet Rays, Transcriptional Activation, Keratinocytes, NF-kappa B, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review