The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
CSF corticotropin-releasing hormone in depressed patients and normal control subjects
Abstract
The authors studied CSF corticotropin-releasing hormone (CRH) and plasma cortisol in 22 depressed patients and 18 normal control subjects. CRH levels were similar in the two groups. Depressed patients who were nonsuppressors on the dexamethasone suppression test had significantly higher levels of CRH than suppressors did. The depressed patients' CRH levels were significantly correlated with 4:00 p.m. postdexamethasone plasma cortisol levels. While the inclusion of a depressed patient with an outlier CRH value resulted in the loss of statistical significance for both of these findings, the authors suggest that these results support the hypothesis that hypercortisolism in depressed patients in part reflects a defect at or above the hypothalamus, resulting in hypersecretion of CRH.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Stress hormones: their interaction and regulation
Axelrod, J., & Reisine, T. D. (1984) · Science · doi:10.1126/science.6143403 · Cited by 1,527
Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin
Gillies, G. E., Linton, E. A., & Lowry, P. J. (1982) · Nature · doi:10.1038/299355a0 · Cited by 965
Research works printed but not linked: 16
- 10.1001/archpsyc.1970.01750040001001 · DOI · Paper page
- Gold P, Loriaux DL, Roy A, etal: The corticotropin releasing factor stimulation test: implications for the diagnosis and pathophysiology of hypercortisolism in primary affective disorders and Cushing's disease. N EngI J Med 1986; 314:1329-1335 · DOI · Paper page
- Schulte H, 1982, Acta Endocrinol (Suppl) (Copenhagen), 253, 32
- 10.1126/science.6334362 · DOI · Paper page
- 10.1136/jnnp.23.1.56 · DOI · Paper page
- 10.1210/jcem-59-6-1103 · DOI · Paper page
- 10.1001/archpsyc.1981.01780260017001 · DOI · Paper page
- Gold PW, Psychiatric implications of basic and clinical studies with corticotropin-releasing Am J Psychiatry 1984
- Davis K, 1984, 137th Annual Meeting of the American Psychiatric Association
- 10.1126/science.6328656 · DOI · Paper page
- 10.1016/0196-9781(82)90071-7 · DOI · Paper page
- 10.1016/0167-0115(82)90107-0 · DOI · Paper page
- 10.1210/endo-110-1-272 · DOI · Paper page
- 10.1016/0024-3205(82)90416-7 · DOI · Paper page
- 10.1038/297331a0 · DOI · Paper page
- 10.1016/0006-8993(86)91142-X · DOI
Cited by
The role of corticotropin-releasing factor in depression and anxiety disorders
Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378
The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression
Müller, N., & Schwarz, M. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002006 · Cited by 670
Neuroendocrine aspects of hypercortisolism in major depression
Parker, K. J., Schatzberg, A. F., & Lyons, D. M. (2003) · Hormones and Behavior · doi:10.1016/s0018-506x(02)00016-8 · Cited by 455
Merali, Z., Du, L., Hrdina, P., Palkovits, M., Faludi, G., Poulter, M. O., & Anisman, H. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4734-03.2004 · Cited by 400
De Souza, E. B. (1995) · Psychoneuroendocrinology · doi:10.1016/0306-4530(95)00011-9 · Cited by 395
Metadata
- Venue
- American Journal of Psychiatry
- Published
- 1987-05-01
- Volume
- 144
- Issue
- 5
- Pages
- 641-645
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2345802250
- Cited by
- 183
- References
- 2
- FWCI
- 4.92
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: CSF corticotropin-releasing hormone in depressed patients and normal control subjects. https://app.cochat.ai/papers/10.1176/ajp.144.5.641
- The paper
- CSF corticotropin-releasing hormone in depressed patients and normal control subjects. (1987). American Journal of Psychiatry. https://doi.org/10.1176/ajp.144.5.641
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
