The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy
Abstract
OBJECTIVE: Because of the role of psychological factors in insomnia, the shortcomings of hypnotic medications, and patients' greater acceptance of nonpharmacological treatments for insomnia, the authors conducted a meta-analysis to examine the efficacy and durability of psychological treatments for the clinical management of chronic insomnia. METHOD: A total of 59 treatment outcome studies, involving 2,102 patients, were selected for review on the basis of the following criteria: 1) the primary target problem was sleep-onset, maintenance, or mixed insomnia, 2) the treatment was nonpharmacological, 3) the study used a group design, and 4) the outcome measures included sleep-onset latency, time awake after sleep onset, number of nighttime awakenings, or total sleep time. RESULTS: Psychological interventions, averaging 5.0 hours of therapy time, produced reliable changes in two of the four sleep measures examined. The average effect sizes (i.e., z scores) were 0.88 for sleep latency and 0.65 for time awake after sleep onset. These results indicate that patients with insomnia were better off after treatment than 81% and 74% of untreated control subjects in terms of sleep induction and sleep maintenance, respectively. Stimulus control and sleep restriction were the most effective single therapy procedures, whereas sleep hygiene education was not effective when used alone. Clinical improvements seen at treatment completion were well maintained at follow-ups averaging 6 months in duration. CONCLUSIONS: The findings indicate that nonpharmacological interventions produce reliable and durable changes in the sleep patterns of patients with chronic insomnia.
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“The recommended first-line treatment, Cognitive Behavioral Therapy for Insomnia (CBTI) does not carry these risks and is therefore preferable for reasons beyond demonstrated efficacy(244-248), efficacy relative to medications(249-253), and effectiveness(254).”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [247]
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“Research suggests that relaxation is especially effective in helping with sleep initiation [29].”
From Non-Pharmacological Treatment of Insomnia (2012) · cites this paper as [29]
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“65) relative to waitlist and placebo control groups.(4) A second meta-analysis conducted by Murtagh and Greenwood(17) including 66 studies concluded that CBT, compared with a placebo control, led to a 24-minute decrease in sleep onset latency (d 5 .”
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“CBT-I has also been shown to have similar effect sizes with respect to sleep continuity [11,12] and comparable or better effects than BZRA hypnotics [13,14].”
ResultResting-State Subjective Experience and EEG Biomarkers Are Associated with Sleep-Onset Latency
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Hypnotic medication in the treatment of chronic insomnia: non nocere! Doesn't anyone care?
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“Go! to Sleep”: A Web-Based Therapy for Insomnia
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Self-citationInterpretive Biases in Chronic Insomnia: An Investigation Using a Priming Paradigm
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Self-citationSleep spindles may predict response to cognitive-behavioral therapy for chronic insomnia
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ResultSLEEP DISORDERS PRESENTING AS PSYCHIATRIC DISORDERS
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A Preliminary Evaluation of the Physiological Mechanisms of Action for Sleep Restriction Therapy
Vallières, A., Ceklic, T., Bastien, C., & Espie, C. A. (2013) · Sleep Disorders · doi:10.1155/2013/726372 · Cited by 24
Insomnia in places of detention: a review of the most recent research findings
Elger, B. S. (2007) · Medicine Science and the Law · doi:10.1258/rsmmsl.47.3.191 · Cited by 24
“…are stimulus control therapy, sleep restriction, sleep hygiene, paradoxical intention, progressive muscle relaxation, and cognitive therapy (Spielman et al., 1987; Morin et al., 1994, 1999; Murtagh and Greenwood, 1995; Edinger et al., 2001; Backhaus et al., 2001; Sateia and Nowell, 2004).”
BackgroundCan mental healthcare nurses improve sleep quality for inpatients?
de Niet, G., Tiemens, B. G., & Hutschemaekers, G. J. M. (2010) · British Journal of Nursing · doi:10.12968/bjon.2010.19.17.78558 · Cited by 23
Health and functional status of twins with chronic regional and widespread pain.
Aaron, L. A., Arguelles, L., Ashton, S., Belcourt, M., Herrell, R. K., Goldberg, J. H., Smith, W. R., Buchwald, D., & Buchwald, D. (2002) · PubMed · Cited by 24
What's wrong with prescribing hypnotics?
(2004) · Drug and Therapeutics Bulletin · doi:10.1136/dtb.2004.421289 · Cited by 24
Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders
Ferracioli-Oda, E., Qawasmi, A., & Bloch, M. H. (2014) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.12.1.73 · Cited by 26
Nonpharmacologic approaches to the management of insomnia.
Lande, R. G., & Gragnani, C. T. (2010) · PubMed · Cited by 22
Efficacy of cognitive behavioral therapy for comorbid insomnia: a meta-analysis
Okajima, I., & Inoue, Y. (2017) · Sleep and Biological Rhythms · doi:10.1007/s41105-017-0124-8 · Cited by 24
Larouche, M., Côté, G., Bélisle, D., & Lorrain, D. (2014) · Pathologie Biologie · doi:10.1016/j.patbio.2014.07.002 · Cited by 23
“However, 20 to 30% of participants suffering from insomnia do not respond to this treatment [19,20].”
BackgroundNichterholsamer Schlaf und Insomnie
Riemann, D., Voderholzer, U., & Berger, M. (2003) · Der Nervenarzt · doi:10.1007/s00115-003-1524-3 · Cited by 18
“Dies ist eine wesentliche Voraussetzung, um Patienten die später noch darzustellenden verhaltenstherapeutischen Techniken zu vermitteln (eine Literaturliste zum Selbststudium s. Infobox).”
BackgroundInfluentialManagement of insomnia: update and new approaches
Riemann, D. W. (2010) · Nature and Science of Sleep · doi:10.2147/nss.s6642 · Cited by 23
“Morin et al included 59 studies to determine the value of pre–post changes on the outcome parameters, such as sleep latency (SL), wake time after sleep onset (WASO), number of awakenings (NOA) and total sleep time (TST), reporting effect sizes (Cohen 85 ) of SL = 0.88, WASO = 0.65, NOA = 0.53, and TST = 0.42.”
InfluentialKempler, L., Sharpe, L., Marshall, N. S., & Bartlett, D. J. (2020) · SLEEP · doi:10.1093/sleep/zsaa101 · Cited by 21
Physical Fitness and Resilience: A Review of Relevant Constructs, Measures, and Links to Well-Being
Robson, S. M. (2014) · Rand health quarterly · doi:10.7249/rhq-03-04-06 · Cited by 23
Optimizing circadian cycles and behavioral insomnia treatment in migraine
Rains, J. C. (2008) · Current Pain and Headache Reports · doi:10.1007/s11916-008-0037-y · Cited by 22
Metadata
- Authors
- Morin, C. M., Culbert, J. P., & Schwartz, S. M.
- Affiliations
- Virginia Commonwealth University (US)
- ORCID
- Charles M. Morin
- Venue
- American Journal of Psychiatry
- Published
- 1994-08-01
- Volume
- 151
- Issue
- 8
- Pages
- 1172-1180
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W1926957827
- Cited by
- 1,098
- References
- 32
- Citations by year
- 2026: 7 · 2025: 19 · 2024: 20 · 2023: 20 · 2022: 19 · 2021: 31 · 2020: 40 · 2019: 28 · 2018: 28 · 2017: 31 · 2016: 40 · 2015: 51 · 2014: 52 · 2013: 48 · 2012: 49
- FWCI
- 6.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r29mh047020-05)
- National Institute of Mental Health (NIMH MH-47020)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- insomnia, non-pharmacological treatment, psychological intervention, sleep onset insomnia, sleep maintenance insomnia, stimulus control, sleep restriction, sleep hygiene education, sleep latency, treatment efficacy, treatment durability
- MeSH terms
- Adult, Behavior Therapy, Biofeedback, Psychology, Chronic Disease, Circadian Rhythm, Female, Follow-Up Studies, Health Education, Humans, Sleep Initiation and Maintenance Disorders, Male, Medical Records, Psychotherapy, Relaxation Therapy, Sleep, Wakefulness, Cognitive Behavioral Therapy, Treatment Outcome
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