CoChat
Sign Up
Cited by 84Hallucinations in medical conditionsSchizophrenia research and treatmentHearing Loss and Rehabilitation

Central Auditory Processing in Patients With Auditory Hallucinations

McKay, Colette M., Headlam, Donna M., Copolov, David L.·2000·American Journal of Psychiatry
DOI 10.1176/appi.ajp.157.5.759
Open this paper in CoChat — free account

Abstract

OBJECTIVE: Data from a full assessment of auditory perception in patients with schizophrenia were used to investigate whether auditory hallucinations are associated with abnormality of central auditory processing. METHOD: Three groups of subjects participated in auditory assessments: 22 patients with psychosis and a recent history of auditory hallucinations, 16 patients with psychosis but no history of auditory hallucinations, and 22 normal subjects. Nine auditory assessments, including auditory brainstem response, monotic and dichotic speech perception tests, and nonspeech perceptual tests, were performed. Statistical analyses for group differences were performed using analysis of variance and Kruskal-Wallis tests. The results of individual patients with test scores in the severely abnormal range (more than three standard deviations from the mean for the normal subjects) were examined for patterns that suggested sites of dysfunction in the central auditory system. RESULTS: The results showed significant individual variability among the subjects in both patient groups. There were no group differences on tests that are sensitive to low brainstem function. Both patient groups performed poorly in tests that are sensitive to cortical or high brainstem function, and hallucinating patients differed from nonhallucinating patients in scores on tests of filtered speech perception and response bias patterns on dichotic speech tests. Six patients in the hallucinating group had scores in the severely abnormal range on more than one test. CONCLUSIONS: Hallucinations may be associated with auditory dysfunction in the right hemisphere or in the interhemispheric pathways. However, comparison of results for the patient groups suggests that the deficits seen in hallucinating patients may represent a greater degree of the same types of deficits seen in nonhallucinating patients.

Integrity signals

Registry

Crossref · 10.1176/appi.ajp.157.5.759

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Most clinical tests of auditory function, such as audiological assessments or far field brainstem potentials, test the most peripheral portions of the inner ear and auditory nerve leading to the brainstem, which do not appear to be affected in schizophrenia.

    “Most clinical tests of auditory function, such as audiological assessments or far field brainstem potentials, are tests of the most peripheral portions of the system in the inner ear and the auditory nerve leading to the brainstem, which do not appear to be affected in schizophrenia (6).”

    From Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia (2015) · cites this paper as [6]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
McKay, C. M., Headlam, D. M., & Copolov, D. L.
Affiliations
The University of Melbourne (AU)
ORCID
Venue
American Journal of Psychiatry
Publisher
American Psychiatric Association Publishing
Published
2000-05-01
Volume
157
Issue
5
Pages
759-766
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
DOI
10.1176/appi.ajp.157.5.759
OpenAlex
W2104625388
Cited by
84
References
27
Citations by year
2024: 3 · 2023: 5 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 6 · 2013: 6 · 2012: 7
FWCI
2.25
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Research Explorer (The University of Manchester) (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
Keywords
auditory hallucinations, central auditory processing, schizophrenia, psychosis, dichotic listening, auditory brainstem response, right hemisphere
MeSH terms
Adult, Audiometry, Auditory Cortex, Auditory Perception, Auditory Perceptual Disorders, Brain Stem, Diagnosis, Differential, Dichotic Listening Tests, Female, Hallucinations, Humans, Functional Laterality, Male, Middle Aged, Schizophrenia, Schizophrenic Psychology, Speech Discrimination Tests, Evoked Potentials, Auditory, Brain Stem

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review