Cited by 341Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesChild and Adolescent Psychosocial and Emotional Development

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Application of DSM-5 Criteria for Autism Spectrum Disorder to Three Samples of Children With DSM-IV Diagnoses of Pervasive Developmental Disorders

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Abstract

OBJECTIVE: Substantial revisions to the DSM-IV criteria for autism spectrum disorders (ASDs) have been proposed in efforts to increase diagnostic sensitivity and specificity. This study evaluated the proposed DSM-5 criteria for the single diagnostic category of autism spectrum disorder in children with DSM-IV diagnoses of pervasive developmental disorders (PDDs) and non-PDD diagnoses. METHOD: Three data sets included 4,453 children with DSM-IV clinical PDD diagnoses and 690 with non-PDD diagnoses (e.g., language disorder). Items from a parent report measure of ASD symptoms (Autism Diagnostic Interview-Revised) and clinical observation instrument (Autism Diagnostic Observation Schedule) were matched to DSM-5 criteria and used to evaluate the sensitivity and specificity of the proposed DSM-5 criteria and current DSM-IV criteria when compared with clinical diagnoses. RESULTS: Based on just parent data, the proposed DSM-5 criteria identified 91% of children with clinical DSM-IV PDD diagnoses. Sensitivity remained high in specific subgroups, including girls and children under 4. The specificity of DSM-5 ASD was 0.53 overall, while the specificity of DSM-IV ranged from 0.24, for clinically diagnosed PDD not otherwise specified (PDD-NOS), to 0.53, for autistic disorder. When data were required from both parent and clinical observation, the specificity of the DSM-5 criteria increased to 0.63. CONCLUSIONS: These results suggest that most children with DSM-IV PDD diagnoses would remain eligible for an ASD diagnosis under the proposed DSM-5 criteria. Compared with the DSM-IV criteria for Asperger's disorder and PDD-NOS, the DSM-5 ASD criteria have greater specificity, particularly when abnormalities are evident from both parents and clinical observation.

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Crossref · 10.1176/appi.ajp.2012.12020276

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Research works printed but not linked: 2

  1. Rutter M, 2003, Social Communication Questionnaire (SCQ)
  2. Constantino JN, 2005, Social Responsiveness Scale (SRS)

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Metadata

Authors
Huerta, M., Bishop, S. L., Duncan, A., Hus, V., & Lord, C.
Affiliations
Cincinnati Children's Hospital Medical Center (US)
Venue
American Journal of Psychiatry
Published
2012-10
Volume
169
Issue
10
Pages
1056-1064
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
OpenAlex
W2111411972
Cited by
341
References
19
Citations by year
2026: 3 · 2025: 13 · 2024: 7 · 2023: 11 · 2022: 13 · 2021: 28 · 2020: 16 · 2019: 20 · 2018: 28 · 2017: 30 · 2016: 35 · 2015: 37 · 2014: 50 · 2013: 43 · 2012: 6
FWCI
22.26
Type
journal article
Language
en
Open access
Locations
  • American Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • Rutgers University Community Repository (Rutgers University) (submittedVersion)
Funders
  • National Institutes of Health (5rc1mh089721-02)
  • National Institute of Mental Health (RC1 MH-089721, R01MH081873)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD065277)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
autism spectrum disorder, DSM-5 diagnostic criteria, DSM-IV, pervasive developmental disorders, sensitivity and specificity, Asperger syndrome, pervasive developmental disorder not otherwise specified, autistic disorder, children
MeSH terms
Adolescent, Autistic Disorder, Child, Child Development Disorders, Pervasive, Child, Preschool, Female, Humans, Male, Psychometrics, Sensitivity and Specificity, Asperger Syndrome, Diagnostic and Statistical Manual of Mental Disorders

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