Standardizing ADOS Domain Scores: Separating Severity of Social Affect and Restricted and Repetitive Behaviors
Open accessAbstract
Standardized Autism Diagnostic Observation Schedule (ADOS) scores provide a measure of autism severity that is less influenced by child characteristics than raw totals (Gotham et al. in Journal of Autism and Developmental Disorders, 39(5), 693-705 2009). However, these scores combine symptoms from the Social Affect (SA) and Restricted and Repetitive Behaviors (RRB) domains. Separate calibrations of each domain would provide a clearer picture of ASD dimensions. The current study separately calibrated raw totals from the ADOS SA and RRB domains. Standardized domain scores were less influenced by child characteristics than raw domain totals, thereby increasing their utility as indicators of Social-Communication and Repetitive Behavior severity. Calibrated domain scores should facilitate efforts to examine trajectories of ASD symptoms and links between neurobiological and behavioral dimensions.
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Standardized scores have been developed for the ADOS-2.
“To address the need for an ASD severity metric, standardized scores have been developed for the ADOS-2 (Gotham et al. 2009; Hus et al. 2013, 2014).”
From Recent Advances in Autism Research as Reflected in DSM-5 Criteria for Autism Spectrum Disorder (2015) · cites this paper as Hus et al. 2014
The ADOS 10-point severity scores are calibrated across different ages and test versions, allowing examination of change in symptom severity over time.
“These 10-point severity scores allow for examining change in symptom severity over time as they are calibrated across different ages and test versions [28].”
From Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study (2015) · cites this paper as [28]
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- Authors
- Hus, V., Gotham, K., & Lord, C.
- Affiliations
- Vanderbilt University (US)
- Cornell University (US)
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2012-11-11
- Volume
- 44
- Issue
- 10
- Pages
- 2400-2412
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- PMC
- PMC3612387
- OpenAlex
- W2051230880
- Cited by
- 568
- References
- 29
- Citations by year
- 2026: 36 · 2025: 30 · 2024: 46 · 2023: 62 · 2022: 57 · 2021: 70 · 2020: 58 · 2019: 50 · 2018: 47 · 2017: 40 · 2016: 29 · 2015: 22 · 2014: 14 · 2013: 7
- FWCI
- 6.95
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Rutgers University Community Repository (Rutgers University) (submittedVersion)
- Funders
- Autism Speaks (AS7032, AS2482)
- National Institutes of Health (5rc1mh089721-02)
- National Institute of Mental Health (RC1 MH-089721, T32MH018921, K01MH103500, R01MH081873)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Keywords
- Autism Diagnostic Observation Schedule, autism severity, social affect, restricted and repetitive behaviors, Z-score, score calibration
- MeSH terms
- Autistic Disorder, Calibration, Child, Humans, Male, Reference Standards, Severity of Illness Index, Social Behavior Disorders, Symptom Assessment
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