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Cited by 51Adipokines, Inflammation, and Metabolic DiseasesNutritional Studies and DietLipoproteins and Cardiovascular Health

Diet, exercise, and C-reactive protein levels in people with abdominal obesity: the ATTICA epidemiological study

Pitsavos, Christos, Panagiotakos, Demosthenes B., Tzima, Natalia, Lentzas, Yannis, Chrysohoou, Christina, Das, Undurti N., Stefanadis, Christodoulos·2007·Angiology
DOI 10.1177/0003319707300014
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Abstract

We evaluated the association of physical activity and diet with C-reactive protein (CRP) levels among subjects with abdominal obesity. During 2001-2002, we enrolled 625 men (18 to 87 years old) and 712 women (18 to 89 years old) with abdominal obesity (waist-to-hip ratio > or =0.95 in men and > or =0.8 in women) from the Attica area, Greece. The sampling was stratified by the age-gender distribution of the region (census 2001). Among several variables, we also measured plasma high-sensitivity CRP, physical activity status, dietary habits, blood lipids, and blood pressure levels. Adherence to the Mediterranean diet was evaluated through a diet score (0 to 55) that assessed the inherent characteristics of the diet. Compared with those with low CRP levels, subjects with high CRP levels (ie, >3.0 mg/L) were physically inactive (P = .01), were less likely to adopt the Mediterranean diet (P = .008), had higher glucose levels, had a higher prevalence of hypertension, had a lower high-density lipoprotein cholesterol, and had increased smoking habits and higher anthropometric indices (all P < .05). Moreover, adoption of the Mediterranean diet in combination with medium physical activity seems to reduce the likelihood of having high CRP levels by 72% (P = .018), irrespective of smoking and various clinical and biological characteristics. Among subjects with abdominal obesity, low-grade systemic inflammation appears to be associated with the adoption of an unfavorable lifestyle, including physical inactivity and unhealthy dietary habits, as well as increased blood pressure levels and low high-density lipoprotein cholesterol.

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  • Among 5181 MESA subjects aged 45-84 years, intakes of vitamin C, vitamin E or β-carotene were not associated with CRP, IL-6 or fibrinogen concentrations after adjusting for a number of factors.

    “Among 5181 subjects from the MESA aged 45 -84 years, intakes of vitamin C, vitamin E or b-carotene were not associated with CRP, IL-6 or fibrinogen concentrations after adjusting for a number of factors (768) .”

    From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [768]

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Authors
Pitsavos, C., Panagiotakos, D. B., Tzima, N., Lentzas, Y., Chrysohoou, C., Das, U. N., & Stefanadis, C.
Affiliations
  • National and Kapodistrian University of Athens (GR)
  • Harokopio University of Athens (GR)
  • UND Life Sciences, Shaker Heights, Ohio
ORCID
Venue
Angiology
Publisher
SAGE Publications
Published
2007-04
Volume
58
Issue
2
Pages
225-233
ISSN
  • 0003-3197 (ISSN-L)
  • 1940-1574
DOI
10.1177/0003319707300014
OpenAlex
W2043500257
Cited by
51
References
36
Citations by year
2026: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2020: 1 · 2017: 3 · 2015: 5 · 2014: 1 · 2013: 5 · 2012: 5
FWCI
3.44
Type
journal article
Language
en
Open access
closed
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations
  • Angiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
Keywords
abdominal obesity, C-reactive protein, physical activity, Mediterranean diet, dietary habits, low-grade inflammation, hypertension, HDL cholesterol, smoking, waist-to-hip ratio, ATTICA study
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Analysis of Variance, Anthropometry, Blood Chemical Analysis, Blood Pressure Determination, C-Reactive Protein, Chronic Disease, Female, Greece, Humans, Male, Middle Aged, Obesity, Population Surveillance, Surveys and Questionnaires, Biomarkers, Exercise, Chi-Square Distribution, Linear Models, Diet, Mediterranean, Abdominal Fat

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