The DOI matches its Crossref record; 115 of the 117 references it cites were found in a registry or an index.
Responses of blood lipids to aerobic, resistance, and combined aerobic with resistance exercise training: a systematic review of current evidence.
Abstract
This review considers the effectiveness of aerobic exercise training with different intensities (moderate and high) as well as the type of exercise (aerobic, resistance, and combined aerobic with resistance) in altering the blood lipids. We reviewed various trials via a systematic search of PubMed, published reviews, and references from original articles. We selected studies that involved aerobic and/or resistance and/or combined exercise training in healthy adults over a limit of 12 weeks and had examined the response of training to one or more of the following: triglycerides, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. We selected a total of 84 studies, 58 were randomized controlled trials. Comparisons between intensities of aerobic exercise programs resulted in favorable effects only for high intensity. The most frequently observed alteration was an increase in the high-density lipoprotein cholesterol, whereas reductions in triglycerides, total cholesterol, and low-density lipoprotein cholesterol appeared less often. Moreover, the evidence of the positive effect of resistance exercise marks out a trend mainly for the low-density lipoprotein cholesterol levels, whereas for combined exercise, results extracted from a short list of published studies show improvements in values of both the high-density lipoprotein cholesterol and the low-density lipoprotein cholesterol. High-intensity aerobic training results in improvement in high-density lipoprotein cholesterol. For resistance and combined exercise, the results are inconsistent. The heterogeneity between the types of exercise did not allow reliable comparisons.
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“The most frequently observed alteration was an increase in the HDL cholesterol, whereas reductions in triglycerides, total cholesterol, and LDL cholesterol appeared less often (160).”
From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [160]
In the citing paper
“A recent meta-analysis comparing aerobic exercise programs showed favorable effects only for highintensity programs.”
From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [160]
In the citing paper
“Previous works were not systematic [14] or included non-randomized trials [13, 15]; limited pooled data analyses have been previously published [16, 17].”
From The Effect of Exercise Training on Blood Lipids: A Systematic Review and Meta-analysis (2025) · cites this paper as [15]
In the citing paper
“Previous work has shown CT [15] with the aerobic component conducted at vigorous [9] or high intensity [5] to be optimal.”
From The Effect of Exercise Training on Blood Lipids: A Systematic Review and Meta-analysis (2025) · cites this paper as [15]
In the citing paper
“Our analysis found superior TC changes with a combination of aerobic and resistance modalities, which is consistent with previous work [15], although a range of study quality designs were considered in that analysis.”
From The Effect of Exercise Training on Blood Lipids: A Systematic Review and Meta-analysis (2025) · cites this paper as [15]
In the citing paper
“An AET intervention ≥ 12 weeks was considered the minimum time to affect lipid profiles [34, 35].”
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Metadata
- Authors
- Tambalis, K., Panagiotakos, D. B., Kavouras, S. A., & Sidossis, L. S.
- Affiliations
- Harokopio University of Athens (GR)
- Corresponding author
- Sidossis, Labros S.
- Venue
- Angiology
- Publisher
- SAGE Publications
- Published
- 2008-10-30
- Volume
- 60
- Issue
- 5
- Pages
- 614-632
- ISSN
- 0003-3197 (ISSN-L)
- 1940-1574
- OpenAlex
- W2118107288
- Cited by
- 224
- References
- 117
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 11 · 2023: 15 · 2022: 16 · 2021: 11 · 2020: 14 · 2019: 15 · 2018: 12 · 2017: 12 · 2016: 16 · 2015: 22 · 2014: 9 · 2013: 18 · 2012: 14
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Angiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Keywords
- serum lipids, aerobic exercise training, resistance training, concurrent training, high-intensity exercise, moderate-intensity exercise, triglycerides, total cholesterol, HDL cholesterol, LDL cholesterol, exercise intensity, cardiovascular risk factors
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Cardiovascular Diseases, Exercise Therapy, Female, Humans, Lipids, Male, Middle Aged, Biomarkers, Treatment Outcome, Evidence-Based Medicine, Dyslipidemias, Resistance Training, Young Adult
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