Cited by 1,026Fibromyalgia and Chronic Fatigue Syndrome ResearchLong-Term Effects of COVID-19Coenzyme Q10 studies and effects

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A report—Chronic fatigue syndrome: Guidelines for research

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Sharpe, M C·1991·Journal of the Royal Society of Medicine

DOI 10.1177/014107689108400224PMC PMC1293107

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Diagnostic and Statistical Manual of Mental Disorders
&NA; (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802020-00022 · Cited by 12,603
Chronic Fatigue Syndrome: A Working Case Definition
Holmes, G. P., KAPLAN, J. E., GANTZ, N. M., KOMAROFF, A. L., SCHONBERGER, L. B., STRAUS, S. E., Jones, J. F., DUBOIS, R. E., CUNNINGHAM-RUNDLES, C., Pahwa, S. G., et al. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-387 · Cited by 1,713
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The postviral fatigue syndrome — an analysis of the findings in 50 cases
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The Frequency of the Chronic Fatigue Syndrome in Patients with Symptoms of Persistent Fatigue
Manu, P., Lane, T. J., & Matthews, D. A. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-7-554 · Cited by 155
Postviral fatigue syndrome: time for a new approach
David, A. S., Wessely, S. C., & Pelosi, A. J. (1988) · BMJ · doi:10.1136/bmj.296.6623.696 · Cited by 150
WHAT IS MYALGIC ENCEPHALOMYELITIS?
Lloyd, A. R., Wakefield, D., Boughton, C. R., & Dwyer, J. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92107-1 · Cited by 144
CHRONIC INFECTIOUS MONONUCLEOSIS
Isaacs, R. (1948) · Blood · doi:10.1182/blood.v3.8.858.858 · Cited by 99
Epidemic Neuromyasthenia — Clinical Syndrome?
Henderson, D. A., & Shelokov, A. (1959) · New England Journal of Medicine · doi:10.1056/nejm195904092601506 · Cited by 96
An Outbreak of Encephalomyelitis in the Royal Free Hospital Group, London, in 1955
Hospital, T. M. S. O. T. R. F. (1957) · BMJ · doi:10.1136/bmj.2.5050.895 · Cited by 85

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Training, supervision and therapists' adherence to manual-based therapy
Cox, D. L., Burgess, M., Chalder, T., Sharpe, M., White, P. D., & Clark, L. (2013) · International Journal of Therapy and Rehabilitation · doi:10.12968/ijtr.2013.20.4.180 · Cited by 4
Complementary and alternative medicine treatments in the management of chronic fatigue syndrome: a systematic review of randomized controlled trials
Kim, K., Chung, W., Song, M., & Chung, S.-H. (2012) · Oriental Pharmacy and Experimental Medicine · doi:10.1007/s13596-012-0096-9 · Cited by 4
Fibromyalgia Syndrome or Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Factors Influencing Work Disability in Women
Löfgren, M., Schult, M., Öhman, A., Julin, P., & Ekholm, J. (2015) · Handbooks in health, work, and disability · doi:10.1007/978-1-4899-7627-7_26 · Cited by 4
Chronisches Erschöpfungssyndrom
Martin, A., & Gaab, J. (2011) · Psychotherapeut · doi:10.1007/s00278-011-0828-1 · Cited by 4
ME/CFS, case definition, and serological response to Epstein-Barr virus. A systematic literature review
Eriksen, W. (2018) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2018.1503125 · Cited by 3
“Perhaps least restrictive, the Oxford criteria [80] were used in only 1 study [48].”
Method
Rehabilitation Programs for Individuals with Chronic Fatigue Syndrome
Taylor, R. R. (2006) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v13n01_05 · Cited by 4
A longitudinal study of exercise metabolism during recovery from viral illness.
Jakeman, P. M. (1993) · British Journal of Sports Medicine · doi:10.1136/bjsm.27.3.157 · Cited by 4
“Recent reports of a riew'5.”
Physiopathological Significance of99mTc HMPAO SPECT Scan Anomalies in Chronic Fatigue Syndrome
Fischler, B., Flamen, P., Everaert, H., Bossuyt, A. M., & Meirleir, K. D. (1998) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v04n04_03 · Cited by 4
The role of sleep in chronic fatigue syndrome: a narrative review
Gotts, Z. M., Ellis, J. G., Newton, J. L., & Deary, V. (2014) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2014.935607 · Cited by 4
“patients without psychiatric disorder,[17] 58 CFS patients with a psychiatric disorder,”
Background
Abnormal Gut Fermentation: Laboratory Studies reveal Deficiency of B vitamins, Zinc, and Magnesium
Eaton, K. K., Howard, J. M., Hunnisett, A., & Harris, M. (2004) · Journal of Nutritional & Environmental Medicine · doi:10.1080/13590840410001734965 · Cited by 4
Nutrient intake is unrelated to nutrient status in patients with chronic fatigue syndrome
Jenkins, M. V., & Rayman, M. P. (2005) · Journal of Nutritional & Environmental Medicine · doi:10.1080/13590840600681751 · Cited by 4
Vocal Fold Deposits in Macrophagic Myofasciitis
Glynn, F. J., & O'Sullivan, P. (2007) · Ear Nose & Throat Journal · doi:10.1177/014556130708600420 · Cited by 4
Controversy over exercise therapy for chronic fatigue syndrome: Continuing the debate
Chalder, T., White, P. D., Sharpe, M., & Mitchell, A. J. (2017) · BJPsych Advances · doi:10.1192/apt.23.5.288 · Cited by 4
Abnormalities in Essential Amino Acids in Patients with Chronic Fatigue Syndrome
Eaton, K. K., & Hunnisett, A. (2004) · Journal of Nutritional & Environmental Medicine · doi:10.1080/13590840410001734938 · Cited by 4
Response to ‘A controversial consensus’; By the International Consensus Panel
Broderick, G. (2011) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2011.02499.x · Cited by 4
A Naturalistic Prospective Study of the Use of Fluoxetine in General Psychiatric Outpatients
Mortimore, C., & Blacker, C. V. R. (1996) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/(sici)1099-1077(199609)11:5 · Cited by 4
Acupuncture for chronic fatigue syndrome
Zhang, W., Liu, Z., Wu, T., & Peng, W. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006010 · Cited by 4
Fatigue symptoms associated with COVID-19 in convalescent or recovered COVID-19 patients; a systematic review and meta-analysisPreprint
Rao, S., Benzouak, T., Gunpat, S., Burns, R. J., Tahir, T. A., Jolles, S. R. A., & Kisely, S. R. (2021) · PsyArXiv (OSF Preprints) · doi:10.31234/osf.io/c4w7p · Cited by 4
Review of Neuroimaging Methods in ME/CFS
Thapaliya, K., Inderyas, M., & Barnden, L. R. (2025) · Methods in molecular biology · doi:10.1007/978-1-0716-4498-0_15 · Cited by 3
Symptom-based survey diagnoses may serve to identify more homogenous sub-groups of fatigue and postviral diseases
Wold, B. K. G., Tveito, K., Angelsen, A., Bringsli, G., Berglund, F., Gustavsen, M., Andersen, G., & Strand, E. B. (2024) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2024.2370209 · Cited by 3
“Although the Fukuda [5] criteria are recommended most often, the CCC [6], ICC [7] and Oxford criteria [4] are also applied in these countries.”
Influential
Anticipation of and response to exercise in adolescents with CFS: An experimental study
Loades, M. E., Chalder, T., Smakowski, A., & Rimes, K. A. (2021) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2021.110490 · Cited by 3
The Facilitation of Clinical and Therapeutic Discoveries in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Related Diseases: Protocol for the You + ME Registry Research Platform
Ramiller, A., Mudie, K., Seibert, E., & Whittaker, S. (2022) · JMIR Research Protocols · doi:10.2196/36798 · Cited by 5
“For all participants, the Registry scores responses to the UK ME/CFS Biobank (UKMEB) Symptoms Assessment Questionnaire to determine fulfillment of distinct ME/CFS case criteria [37], including the CDC-1994 (Fukuda) criteria [38], the Canadian Consensus criteria [39], the International Consensus criteria [40], the Inst…”
Method
Beyond the Clinic: Virtual Care as the Future of Long COVID Rehabilitation
Anderson, M., & Bauer, N. (2024) · Cardiopulmonary Physical Therapy Journal · doi:10.1097/cpt.0000000000000278 · Cited by 3
“30,31 35-37 However, PEM has historically not been well de ﬁ ned or taught to PTs despite the phenomenon of PEM being described as early as 1986.”
Body Weight May Have a Role on Neuropathy and Mobility after Moderate to Severe COVID-19: An Exploratory Study
Figueroa-Padilla, I., Fernández, D. E. R., Cházaro-Rocha, E. F., Gutiérrez, A. L. E., & Jáuregui‐Renaud, K. (2022) · Medicina · doi:10.3390/medicina58101401 · Cited by 4
“Post-infectious fatigue syndrome is a subtype of chronic fatigue syndrome [48] that either follows an infection or is associated with a current infection, which cannot be explained by other medical or psychiatric conditions and has been present for at least six months (affecting daily functioning), and fulfill specifi…”
Background
Gene Expression in Chronic Fatigue Syndrome
Ekua, W., Kevin, J., Gunn, M., Donald, R., & Marshall‐Gradisnik, S. (2012) · InTech eBooks · doi:10.5772/30342 · Cited by 3
“A diagnosis of CFS is made using questionnaires which include Centre for Disease Prevention and control criteria for CFS, the Australian, British and Canadian CFS classifications and the recently developed World Health Organisation’s International Classification of Diseases for CFS (Carruthers et al., 2011, Carruthers…”
Method
Overview of MR Diffusion Tensor Imaging and Spatially Normalized FDG-PET for Diffuse Axonal Injury Patients with Cognitive Impairments
Okumura, A., Shinoda, J., & Yamada, J. (2008) · Springer eBooks · doi:10.1007/978-4-431-73464-2_2 · Cited by 3
Psychomotor Functioning in Chronic Fatigue Syndrome
Sargent, C., Anderson, S., & Budek, M. (1997) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v03n03_04 · Cited by 3
Chronic fatigue syndrome
Welsh, L. (2000) · British Journal of Therapy and Rehabilitation · doi:10.12968/bjtr.2000.7.2.13902 · Cited by 3
Child and adolescent chronic fatigue syndrome/myalgic encephalomyelitis: where are we now?
Gregorowski, A., Simpson, J., & Segal, T. Y. (2019) · Current Opinion in Pediatrics · doi:10.1097/mop.0000000000000777 · Cited by 3
“Several definitions exist to define CFS/ME including the Fukuda definition [9], the Oxford criteria [10] and the National Institute for Health and Clinical Excellence (NICE) guidelines [11].”
Interventions to treat pain in paediatric CFS/ME: a systematic review
Ascough, C., King, H., Serafimova, T., Beasant, L., Jackson, S., Baldock, L., Pickering, A. E., Brooks, J. C. W., & Crawley, E. M. (2020) · BMJ Paediatrics Open · doi:10.1136/bmjpo-2019-000617 · Cited by 3
Mildronate. Chronic fatigue syndrome
Филиппова, А. В., Pereverzev, A. P., Ebzeeva, E. Y., & Ostroumova, O. D. (2020) · Medical alphabet · doi:10.33667/2078-5631-2020-7-15-20 · Cited by 3
Efficacy and safety of Mildronate in treatment of postinfectious asthenic syndrome (clinical examples)
Ebzeeva, E. Y., Ostroumova, O. D., & Mironova, E. V. (2020) · Medical alphabet · doi:10.33667/2078-5631-2020-2-61-66 · Cited by 3
Beliefs about sharing illness experiences in chronic fatigue syndrome: the role of interpersonal trust and personality
Shabahang, R., Sheykhangafshe, F. B., Aruguete, M. S., & Hossienkhanzadeh, A. (2020) · Health Psychology Report · doi:10.5114/hpr.2020.99395 · Cited by 3
“According to the medical records and results of screening, participants all met the criteria for the clinical diagnosis of chronic fatigue syndrome (Haney et al., 2015; Morris & Maes, 2013; Sharpe et al., 1991).”
Method
Chronic Fatigue Syndrome
Wessely, S. C. (1999) · Springer eBooks · doi:10.1007/978-4-431-68500-5_10 · Cited by 4
Somatoforme Störungen
Kapfhammer, H. (2011) · Springer eBooks · doi:10.1007/978-3-642-03637-8_61 · Cited by 3
Traditional Chinese medicinal herbs for idiopathic chronic fatigue and chronic fatigue syndrome
Adams, D., Wu, T., Tai, S., Wiebe, N., & Vohra, S. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006348 · Cited by 3
Retracted
The role of sleep in chronic fatigue syndrome
Gotts, Z. M. (2014) · Northumbria Research Link (Northumbria University) · Cited by 3
Fluoxetine and chronic fatigue syndrome
Cleare, A. J., Wessely, S. C., Sharma, A. K., Kendall, M. J., Oyebode, F., Jones, D. A., Lynch, S., Seth, R., & Vercoulen, J. H. M. M. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90851-x · Cited by 3
Double disability : lived experience of Australian tertiary students with ME/CFS
Morris, D. (2003) · Figshare · Cited by 3
Chronic fatigue syndrome Health and impairment, treatment and prognosis
Stubhaug, B. (2008) · NORA - Norwegian Open Research Archives · Cited by 3
Altered Recovery Process after Fatiguing Exercise and Potential Benefits of Qigong in Patients with Fibromyalgia
Cocke, M. (2015) · KU ScholarWorks (The University of Kansas) · Cited by 3
Chronic fatigue
Stevens, D. L. (2001) · Western Journal of Medicine · doi:10.1136/ewjm.175.5.315 · Cited by 3
Lewy bodies
Curran, S., & Wrigley, M. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.9.1322b · Cited by 2
Muscle strength, muscle endurance, voluntary activation, and perception of effort in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): an overview
Nuzzo, J. L., Taylor, J. L., & Latella, C. (2025) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2025.2556941 · Cited by 2
“…for ME/CFS based on one or more of the following sets of guidelines: Centers for Disease Control and Prevention (CDC) – Holmes et al. 1988 [23], Oxford – Sharpe et al. 1991 [16], CDC – Fukada et al. 1994 [13], and Canadian Consensus Criteria (CCC) – Carruthers et al. 2003 [21] (see Table 1).”
The Aerobic Energy Production and the Lactic Acid Excretion are both Impeded in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Vink, M. (2015) · Journal of Neurology and Neurobiology · doi:10.16966/2379-7150.112 · Cited by 2
“7 [68] which where created so that people with other conditions could be included in so called ME/CFS studies, and the American P2P recentlyconcluded that the Oxford criteria confound the ability to interpret the science, that “continuing to use the Oxford definition may impair progress and cause harm.”
Humanistic and Holistic Strategies for Combating Mental Health Sequelae in the Elderly During the Post-COVID Era
Maity, K., Lal, P., Jyoti, S., Bali, P., Thakur, U. K., Singh, G., Majumdar, V., Patra, S., Arya, J., & Anand, A. (2024) · Annals of Neurosciences · doi:10.1177/09727531231208292 · Cited by 2
“39 Also, COVID-19 infection showed similar symptoms.”
Rasch analysis of the hospital anxiety and depression scale in patients with chronic fatigue syndrome
Bartholomew, E. J., Medvedev, O. N., Petrie, K. J., & Chalder, T. (2025) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2025.112370 · Cited by 2
Chronic Fatigue Syndrome Prevalence and its Relation to Job Performance among Nurses
Haddadi, M., Zakerian, S. A., Mahmoudi, M., Saraji, G. N., Yekta, Z. P., & Aliyari, A. (2015) · Universal Journal of Public Health · doi:10.13189/ujph.2015.030101 · Cited by 2
Síndrome de fatiga crónica en una adolescente de 15 años
Greciano, A. D.-C., Sosa, J. T. R., Aguilera, S., Sánchez-Carpintero, R., & Soutullo, C. A. (2007) · Anales de Pediatría · doi:10.1157/13108085 · Cited by 2
Behandeling van chronische vermoeidheid met cognitieve gedragstherapie
Keijsers, G. P. J., Hosselet, G., & van Minnen, A. (1996) · Directieve therapie · doi:10.1007/bf03060146 · Cited by 2
Chronic Fatigue Syndrome
Jung, S. P., & Lee, K. M. (2007) · Journal of Yeungnam Medical Science · doi:10.12701/yujm.2007.24.1.1 · Cited by 2
“Risdale et al, 2001 GBT and counseling RCT CDC 1994 26(13) 45 PH;PS;QOL <> <> 18”
BackgroundInfluential
Pasienter ut av ingenmannsland: Registeret for myalgisk encefalopati – ME/post viralt fatigue syndrom – PVFS.
Kreyberg, S. E. (2009) · Norsk Epidemiologi · doi:10.5324/nje.v14i1.279 · Cited by 2
“Psykosomatikken lanserte i 1991 en helt ny definisjon av ”chronic fatigue syndrome”, den såkalte Oxforddefinisjonen (12).”
BackgroundInfluential
Three Approaches to Chronic Fatigue Syndrome in the United Kingdom, Australia, and Canada: Lessons for Democratic Policy
Ankeny, R. A., & Mackenzie, F. J. (2016) · The International library of ethics, law and technology · doi:10.1007/978-3-319-32240-7_11 · Cited by 2
Hvordan er det å være ungdom og leve med kronisk utmattelsessyndrom/myalgisk encefalopati? En narrativ oversikt [How is it to be an adolescent living with chronic fatigue syndrome/myalgic encephalomyelitis? A narrative review]
Rødevand, L. N. (2017) · Scandinavian Psychologist · doi:10.15714/scandpsychol.4.e1 · Cited by 2
Greater specificity of activity memories in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Implications for exercise-based treatment
Martin, M., & Alexeeva, I. (2017) · Mental health and physical activity · doi:10.1016/j.mhpa.2017.12.003 · Cited by 2
“Other diagnostic criteria for CFS/ME, such as the Oxford criteria (Sharpe et al., 1991), do not exclude patients with depression.”
Background
Chronic Fatigue Syndrome
Rea, T. D., & Buchwald, D. (2000) · Elsevier eBooks · doi:10.1016/b978-012288145-9/50097-8 · Cited by 2
Multiaspective diagnostics of training loads as well as biomechanical parameters and blood indices among leadingelite race walkers preparing for participation in the olympics
Mleczko, E., Mirek, W., Dąbrowski, Z., Frączek, B., Forczek, W., Sudoł, G., & Gradek, J. (2019) · Journal of Kinesiology and Exercise Sciences · doi:10.5604/01.3001.0015.5535 · Cited by 2
“The signalled problem turned out to be so interesting to solve in a cognitive and applicative sense in scientific research, that already in the last decade of the 20 century, discussion panels of scientists from the round table were organised in Oxford (Green College, March 23, 1990 [23] and at St.”
Background
Influenza Virus, Enteroviruses, and Other Epidemic Viruses
(2014) · ASM Press eBooks · doi:10.1128/9781555817831.ch10 · Cited by 2
Investigating Post-Exertional Malaise as a Core Symptom of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome: A Meta-Analytic Approach
Brown, A. A. (2017) · Digital Commons-DePaul (DePaul University) · Cited by 2
Myalgia☆
Bockman, C. S., Eckerson, J. M., & McCarson, K. E. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.05161-8 · Cited by 2
Development of the 1994 Chronic Fatigue Syndrome Case Definition and Clinical Evaluation Guidelines
Fukuda, K. (1997) · Springer eBooks · doi:10.1007/978-1-4615-5953-5_2 · Cited by 2
Phantom lymphadenopathy. An association with chronic fatigue syndrome
Shee, C. D. (2003) · Postgraduate Medical Journal · doi:10.1136/pmj.79.927.59 · Cited by 2
The Rise and Fall of the Chronic Fatigue Syndrome as Defined by Holmes et al
Waveren, E. K. V. (1996) · Medical Hypotheses · doi:10.1016/s0306-9877(96)90001-8 · Cited by 2
Chronic fatigue syndrome
Welsh, L. (1996) · Practice Nursing · doi:10.12968/pnur.1996.7.16.29 · Cited by 2
Tumorous xanthomas in a young male with familial hypercholesterolaemia
Rajput, R. (2006) · Archives of Disease in Childhood · doi:10.1136/adc.2006.101535 · Cited by 2
From Violation to Reconstruction: The Process of Self-Renewal Associated with Chronic Fatigue Syndrome
Travers, M. K. (2004) · The Sydney eScholarship Repository (The University of Sydney) · Cited by 2
Chronic Fatigue Syndrome in Practice
Afari, N., van der Meer, J. W., Bleijenberg, G., & Buchwald, D. (2005) · Psychiatric Annals · doi:10.3928/00485713-20050401-08 · Cited by 2
Psychomotor Speed as a Marker for Overtraining in Athletes: A Multidisciplinary Approach
Mulder, T. W., & Nederhof, E. (2003) · Cited by 2
Cognitive functioning in chronic fatigue syndrome
Cockshell, S. J. (2016) · Adelaide Research & Scholarship (AR&S) (University of Adelaide) · doi:10.4225/55/58dc8dc6dc266 · Cited by 2
“1988; 1990) UK Definition (Sharpe et al. 1991) US NIH Definition (Schluederberg et al.”
BackgroundMethodInfluential
Chronic Fatigue Syndrome
Hunt, N. (1998) · CRC Press eBooks · doi:10.1201/b14648-4 · Cited by 2
Somatoforme Störungen
Kapfhammer, H. (2003) · Springer eBooks · doi:10.1007/3-540-27386-7_56 · Cited by 2
The Disrupted and Realigned Self: Exploring the Narratives of New Zealanders with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Bell, L. J. M. (2013) · doi:10.26686/wgtn.17003698.v1 · Cited by 2
Comprehensive profiling of the human intestinal DNA virome and prediction of disease-associated bacterial hosts in severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)Preprint
Hsieh, S.-Y., Savva, G. M., Telatin, A., Tiwari, S. K., Tariq, M., Newberry, F., Seton, K. A., Booth, C., Bansal, A. S., Wileman, T. E., et al. (2023) · medRxiv · doi:10.1101/2023.06.29.23291738 · Cited by 2
Chronic unexplained fatigue
White, P. D. (1999) · Acta Neuropsychiatrica · doi:10.1017/s0924270800035870 · Cited by 1
Stress and psychological trauma as predictors of cancer-related fatigue in breast cancer patients (SaFE study)—study protocol of a prospective follow-up study
Hofmann, H., Koch, T., Brucker, C. V. M., Radermacher, P., Müller, M., Waller, C., & Stein, B. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1691485 · Cited by 1
Does Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Represent a Poly-Herpesvirus Post-Virus Infectious Disease?
Ariza, M. E., Palomo, I. M., & Williams, M. V. (2025) · Viruses · doi:10.3390/v17121624 · Cited by 1
Tuina therapy for patients with chronic fatigue syndrome: a randomized controlled trial
Wang, S., Ren, J. Y., Zhou, X., Fang, S., He, T., Wu, Z., Xu, S., Kong, L., & Fang, M. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-025-07624-7 · Cited by 1
Chronic fatigue syndrome Role of psychological factors overemphasised
Blatch, C., & Blatt, T. (1994) · BMJ · doi:10.1136/bmj.308.6939.1297 · Cited by 1
Onset Patterns of Chronic Fatigue Syndrome and Myalgic Encephalomyelitis: A Mixed Method Approach
Evans, M. A. (2015) · Digital Commons-DePaul (DePaul University) · Cited by 1
Multidisciplinary group treatment for chronic fatigue syndrome
Belgamwar, R. B., Jorsh, M., Knisely‐Marpole, A., Snowden, H. M., Mayall, E. S., Singhal, A., & Jm, J. (2009) · Progress in Neurology and Psychiatry · doi:10.1002/pnp.109 · Cited by 1
Daytime Sleepiness and REM Sleep Abnormalities in Chronic Fatigue
Ambrogctti, A., Olson, L. G., Sutherland, D. C., Malcolm, J. A., Bliss, D., & Gyulay, S. G. (1998) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v04n01_04 · Cited by 1
Cognitive Function and Major Depression in Chronic Fatigue: The Apathy Construct
Axe, E. K., Satz, P., & Fawzy, F. I. (2007) · Journal of Chronic Fatigue Syndrome · doi:10.3109/10573320802091841 · Cited by 1
Differential Diagnosis of Vasovagal Syncope: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Sarzi‐Puttini, P., Batticciotto, A., Talotta, R., & Atzeni, F. (2014) · Springer eBooks · doi:10.1007/978-3-319-09102-0_16 · Cited by 1
“The CDC recommends an initial urinalysis, complete blood count, a comprehensive metabolic panel, and the measurement of phosphorus, thyroid-stimulating hormone, and C-reactive protein levels [ 50 ].”
BackgroundMethod
A Reexamination of the Cognitive Behavioral Model of Chronic Fatigue Syndrome: Investigating the Cogency of the Model’s Behavioral Pathway
Sunnquist, M. (2016) · Digital Commons-DePaul (DePaul University) · Cited by 1
The effects of therapies for Myalgic Encephalomyelitis and chronic fatigue syndrome should be assessed using objective measures
Twisk, F. (2017) · Medical Research and Innovations · doi:10.15761/mri.1000118 · Cited by 1
“According to the original PACE protocol [24] people were eligible if they met the Oxford criteria for chronic fatigue (CF) [25], implicating a CFB score ≥6 (CFL >12), and the SF-36 PF score was ≤65.”
Method
The PACE Trial’s GET Manual for Therapists Exposes the Fixed Incremental Nature of Graded Exercise Therapy for ME/CFS
Vink, M., & Partyka-Vink, K. (2025) · Life · doi:10.3390/life15040584 · Cited by 1
“Respectively, five (Oxford criteria) and three authors (Fukuda criteria) of White et al. [6] were involved in removing PEM as a compulsory criterion for the diagnosis of ME/CFS in 1991 and 1994 [32,33].”
Xenotropic Murine Leukemia Virus-Related Virus as a Case Study: Using a Precautionary Risk Management Approach for Emerging Blood-Borne Pathogens in Canada
Michael, G., ElSaadany, S., Oraby, T. F., Laderoute, M. P., Wu, J., Aspinall, W. P., Krewski, D. R., & Peter, R. (2012) · InTech eBooks · doi:10.5772/38572 · Cited by 1
“…to select research subjects include the Canadian Consensus Criteria for CFS-ME published in 2003 (Carruthers et al., 2003), Holmes et al.’s CFS working case definition (Holmes et al., 1988), the Oxford criteria (Sharpe et al., 1991) and the CDC clinically empirical approach (Reeves et al., 2005).”
A Systematic Review of Acupuncture for Chronic Fatigue Syndrome
Kim, H. G., Ryoo, D. W., Jeong, S. M., Kim, S. J., Baek, S. W., Lee, C. H., Yoon, J. Y., Goo, B., Kim, M. J., Park, Y., et al. (2017) · 대한침구학회지 · doi:10.13045/acupunct.2017086 · Cited by 1
Chronic fatigue syndrome
Spender, Q. W., Salt, N., Dawkins, J., Kendrick, T., Hill, P., Hall, D., & Carnell, J. (2018) · CRC Press eBooks · doi:10.1201/9781315378428-41 · Cited by 1
Myalgia
Bockman, C. S., & Eckerson, J. M. (2007) · xPharm: The Comprehensive Pharmacology Reference · doi:10.1016/b978-008055232-3.60687-7 · Cited by 1
Particular experiences: a psychosocial exploration of myalgic encephalomyelitis (ME) and its relationship with self, environment and the material world
Fellenor, J. (2015) · The University of Bath Online Publications Store (The University of Bath) · Cited by 1
Das chronische Müdigkeitssyndrom (die chronische Erschöpfbarkeit) und seine Beziehung zum Fibromyalgiesyndrom
Hoffmann, A., & Linder, R. (1999) · Springer eBooks · doi:10.1007/978-3-662-00574-3_2 · Cited by 1
Muscular Pain Mechanisms: Brief Review with Special Consideration of Delayed-Onset Muscle Soreness
Mizumura, K. (2008) · Springer eBooks · doi:10.1007/978-4-431-73242-6_12 · Cited by 1
Mit chronischem Müdigkeits- bzw. Fibromyalgie- syndrom assoziierte Manifestationen: Ausdruck einer Dysbalance im neuroendokrinoimmunologischen Regelkreis?
Klein, R. (2003) · Springer eBooks · doi:10.1007/978-3-642-19026-1_2 · Cited by 1
Cytokine Expression and Morphology ofin vitroGrown Monocytes from Patients with Chronic Fatigue Syndrome
Gimenez, H. B., Cash, P., Laing, R. B. S., & Douglas, J. G. (1999) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v05n01_05 · Cited by 1
Bailliere's Clinical Neurology-Inflammatory Neuropathies
Scolding, N. J. (1995) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.58.6.765-b · Cited by 1
MATTERS ARISING: Bonner et al reply:
Bonner, D., Ron, M. A., Chalder, T., Butler, S., & Wessely, S. C. (1995) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.58.6.765 · Cited by 1
Postviral fatigue syndrome: Author's reply
Behan, P. O. (1992) · BMJ · doi:10.1136/bmj.304.6841.1567 · Cited by 1
Chronic Fatigue Syndrome in Army General Practice
Johnston, J. (1994) · Journal of the Royal Army Medical Corps · doi:10.1136/jramc-140-02-01 · Cited by 1
“The diagnosis is simply established by a history of disabling fatigue for more than six months with no obvious physical disease to explain it (2).”
Background
Unexplained Prolonged Fatigue in Primary Care
Wu, H.-S., & Mengel, M. B. (2006) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v13n01_03 · Cited by 1

Authors: Sharpe, M. C.
Affiliations: Warneford Hospital (GB)
Corresponding author: Sharpe, M C
ORCID: Sharpe, M C
Venue: Journal of the Royal Society of Medicine
Publisher: SAGE Publications
Published: 1991-02
Volume: 84
Issue: 2
Pages: 118-121
ISSN: 0141-0768 (ISSN-L)
1758-1095
DOI: 10.1177/014107689108400224
PMC: PMC1293107
OpenAlex: W1538919177
Cited by: 1,026
References: 16
Citations by year: 2026: 8 · 2025: 17 · 2024: 19 · 2023: 13 · 2022: 13 · 2021: 28 · 2020: 26 · 2019: 36 · 2018: 28 · 2017: 37 · 2016: 41 · 2015: 32 · 2014: 22 · 2013: 32 · 2012: 21
FWCI: 28.92
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of the Royal Society of Medicine (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Wellcome Trust
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Coenzyme Q10 studies and effects
Keywords: chronic fatigue syndrome, research guidelines, research priorities
MeSH terms: Humans, Methods, Research, Fatigue Syndrome, Chronic

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