Interaction of Theory and Practice to Assess External Validity
Abstract
Background: Variations in local context bedevil the assessment of external validity: the ability to generalize about effects of treatments. For evaluation, the challenges of assessing external validity are intimately tied to the translation and spread of evidence-based interventions. This makes external validity a question for decision makers, who need to determine whether to endorse, fund, or adopt interventions that were found to be effective and how to ensure high quality once they spread. Objective: To present the rationale for using theory to assess external validity and the value of more systematic interaction of theory and practice. Methods: We review advances in external validity, program theory, practitioner expertise, and local adaptation. Examples are provided for program theory, its adaptation to diverse contexts, and generalizing to contexts that have not yet been studied. The often critical role of practitioner experience is illustrated in these examples. Work is described that the Robert Wood Johnson Foundation is supporting to study treatment variation and context more systematically. Results: Researchers and developers generally see a limited range of contexts in which the intervention is implemented. Individual practitioners see a different and often a wider range of contexts, albeit not a systematic sample. Organized and taken together, however, practitioner experiences can inform external validity by challenging the developers and researchers to consider a wider range of contexts. Researchers have developed a variety of ways to adapt interventions in light of such challenges. Conclusions: In systematic programs of inquiry, as opposed to individual studies, the problems of context can be better addressed. Evaluators have advocated an interaction of theory and practice for many years, but the process can be made more systematic and useful. Systematic interaction can set priorities for assessment of external validity by examining the prevalence and importance of context features and treatment variations. Practitioner interaction with researchers and developers can assist in sharpening program theory, reducing uncertainty about treatment variations that are consistent or inconsistent with the theory, inductively ruling out the ones that are harmful or irrelevant, and helping set priorities for more rigorous study of context and treatment variation.
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The classification system's focus on targets of action (levels and determinants) has potential to aid in selecting and strategically combining multiple strategies.
“Consistent with the intent of Proctor et al.’s guidelines, this classification system’s focus on targets of action (levels and determinants) has potential to aid in selecting and strategically combining multiple strategies [45, 46].”
From Beyond “implementation strategies”: classifying the full range of strategies used in implementation science and practice (2017) · cites this paper as [45]
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Westbrook, T. R. (2017) · Evaluation Review · doi:10.1177/0193841x17707908 · Cited by 1 · see citing works
Zamir, M., & Kaunert, C. (2025) · Advanced sciences and technologies for security applications · doi:10.1007/978-3-031-89110-6_2 · Cited by 1 · see citing works
External Validity for Complex Interventions: Towards Pragmatic Strategies for Evaluators
Delahais, T. (2025) · Evaluation Review · doi:10.1177/0193841x251343130 · Cited by 1 · see citing works
Additional file 1 of Quality improvement studies in nursing homes: a scoping review
Toles, M., Colon-Emeric, C. S., Moreton, E., Frey, L., & Leeman, J. (2021) · Figshare · doi:10.6084/m9.figshare.15161894
Additional file 2 of Quality improvement studies in nursing homes: a scoping review
Toles, M., Colon-Emeric, C. S., Moreton, E., Frey, L., & Leeman, J. (2021) · Figshare · doi:10.6084/m9.figshare.15161897
Acquah, D. K., Kung, C. S. J., & Sherlock, R. M. (2026) · Behavioral Sciences · doi:10.3390/bs16050626
- Authors
- Leviton, L. C., & Trujillo, M. D.
- Affiliations
- Robert Wood Johnson Foundation (US)
- Corresponding author
- Leviton, Laura C.
- ORCID
- Leviton, Laura C.
- Venue
- Evaluation Review
- Publisher
- SAGE Publications
- Published
- 2016-01-18
- Volume
- 41
- Issue
- 5
- Pages
- 436-471
- ISSN
- 0145-4692 (ISSN-L)
- 0193-841X
- 1552-3926
- OpenAlex
- W2343651394
- Cited by
- 35
- References
- 84
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 2 · 2023: 5 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 2 · 2018: 5 · 2017: 5 · 2016: 2
- FWCI
- 8.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Evaluation Review (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Social Sciences › Decision Sciences › Management Science and Operations Research › Evaluation and Performance Assessment
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Keywords
- generalizability, program theory, practitioner expertise, local adaptation, context effects, treatment variation, evidence-based interventions, theory-practice interaction, intervention development, systematic inquiry
- MeSH terms
- Decision Making, Evaluation Studies as Topic, Models, Theoretical, Policy Making, Reproducibility of Results, Evidence-Based Practice
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