CoChat
Sign Up
Cited by 154Neuroendocrine regulation and behaviorStress Responses and CortisolNeuropeptides and Animal Physiology

The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.

Anxiolytic-like effect of oxytocin in the simulated public speaking test

de Oliveira, Danielle CG, Zuardi, Antonio W, Graeff, Frederico G, Queiroz, Regina HC, Crippa, José AS·2012·Journal of Psychopharmacology
DOI 10.1177/0269881111400642
Open this paper in CoChat — free account

Abstract

Oxytocin (OT) is known to be involved in anxiety, as well as cardiovascular and hormonal regulation. The objective of this study was to assess the acute effect of intranasally administered OT on subjective states, as well as cardiovascular and endocrine parameters, in healthy volunteers ( n = 14) performing a simulated public speaking test. OT or placebo was administered intranasally 50 min before the test. Assessments were made across time during the experimental session: (1) baseline (−30 min); (2) pre-test (−15 min); (3) anticipation of the speech (50 min); (4) during the speech (1:03 h), post-test time 1 (1:26 h), and post-test time 2 (1:46 h). Subjective states were evaluated by self-assessment scales. Cortisol serum and plasma adrenocorticotropic hormone (ACTH) were measured. Additionally, heart rate, blood pressure, skin conductance, and the number of spontaneous fluctuations in skin conductance were measured. Compared with placebo, OT reduced the Visual Analogue Mood Scale (VAMS) anxiety index during the pre-test phase only, while increasing sedation at the pre-test, anticipation, and speech phases. OT also lowered the skin conductance level at the pre-test, anticipation, speech, and post-test 2 phases. Other parameters evaluated were not significantly affected by OT. The present results show that OT reduces anticipatory anxiety, but does not affect public speaking fear, suggesting that this hormone has anxiolytic properties.

Overview

Integrity signals

Registry

Crossref · 10.1177/0269881111400642

Cites

66 of 66 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 66 references

Research works printed but not linked: 6

  1. First MB, 1997, Structured Clinical Interview for DSM-IV Axis I Disorders (SCID), Clinician Version
  2. Lupien SJ, 1997, J Clin Endocrinol Metabol, 82, 2070
  3. Osório FL, 2008, Rev Psiq Clin, 135, 207
  4. Palma SM, 1994, Braz J Med Biol Res, 27, 2895
  5. 10.1210/endo.138.7.5255 · DOI · Paper page
  6. Zuardi AW, 1981, J Bras Psiquiatr, 131, 403

Cited by

Sorted by citations

Items 101–154 of 154

Related

See all

Metadata

Authors
de Oliveira, D. C., Zuardi, A. W., Graeff, F. G., Queiroz, R. H., & Crippa, J. A.
Affiliations
  • Department of Neurosciences and Behavior, Division of Psychiatry, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  • Universidade de São Paulo (BR)
  • National Science and Technology Institute (INCT) for Translational Medicine, CNPq, Ribeirão Preto, São Paulo, Brazil
ORCID
Graeff, Frederico G
Venue
Journal of Psychopharmacology
Publisher
SAGE Publications
Published
2011-05-09
Volume
26
Issue
4
Pages
497-504
ISSN
  • 0269-8811 (ISSN-L)
  • 1461-7285
DOI
10.1177/0269881111400642
OpenAlex
W2023279242
Cited by
154
References
66
Citations by year
2026: 5 · 2025: 11 · 2024: 3 · 2023: 9 · 2022: 5 · 2021: 6 · 2020: 14 · 2019: 8 · 2018: 15 · 2017: 12 · 2016: 17 · 2015: 10 · 2014: 17 · 2013: 12 · 2012: 7
FWCI
16.93
Type
journal article
Language
en
Open access
closed
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations
  • Journal of Psychopharmacology (publishedVersion)
  • PubMed (publishedVersion)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (publishedVersion)
Funders
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Keywords
oxytocin, anxiolytic effects, anticipatory anxiety, public speaking anxiety, speech performance, intranasal administration, cortisol, ACTH, heart rate, blood pressure, skin conductance, sedation
MeSH terms
Administration, Intranasal, Adrenocorticotropic Hormone, Adult, Fear, Humans, Hydrocortisone, Oxytocin, Speech, Anti-Anxiety Agents

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review