Cited by 199Neural and Behavioral Psychology StudiesTreatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record; 71 of the 72 references it cites were found in a registry or an index.

Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression.

Goodwin, Guy M.·1997·Journal of Psychopharmacology

DOI 10.1177/026988119701100204

Open this paper in CoChat — free account

Abstract

The onset and reversibility of major depression is likely to be explained by diffuse neuromodulatory mechanisms rather than permanent abnormalities of connectivity and neurotransmission. However, the expression of mood state appears to involve fronto-striatal mechanisms. Lesions of the ventral frontal cortex give rise to profound modification of affect and behaviour not explained by effects on current intellectual function. These may represent the most extreme possible disturbances of emotional experience. Neuropsychological testing in major depression shows evidence of slowing in motor and cognitive domains with additional prominent effects on mnemonic function most marked in the elderly. Structural imaging with X-ray computed tomography or magnetic resonance imaging in older patients with major depression shows evidence of structural abnormality compared with controls. These findings are not highly localizing but they tend to confirm the role of cognitive impairment as an important age-related risk factor for major depression. Perfusion or metabolic imaging reflects both reversible changes in function and permanent loss of active neurones. The usual finding has been reductions in anterior brain structures in major depression. Hypoperfusion tends to be greatest in frontal, temporal and parietal areas and most extensive in older (male) patients; high Hamilton scores tend to be associated with reduced uptake. There have also been correlations in the cingulate cortex between increased perfusion and other aspects of the mental state. In general, reductions in frontal areas may be more likely in patients with impoverished mental states. The more prominent impairments of memory are likely to be associated with the finding of impaired temporal function or with a more diffuse failure of neuromodulation.

Integrity signals

Registry

Crossref · 10.1177/026988119701100204

Cites

71 of 71 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527
From Neuropsychology to Mental Structure
Shallice, T. (1988) · doi:10.1017/cbo9780511526817 · Cited by 4,072
Contributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377
Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions.
Alexander, G. E., Crutcher, M. D., & DeLong, M. R. (1990) · PubMed · Cited by 2,422
Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala
Adolphs, R., Tranel, D., Damasio, H., & Damasio, A. (1994) · Nature · doi:10.1038/372669a0 · Cited by 2,360
Chapter 6 Basal ganglia-thalamocortical circuits: Parallel substrates for motor, oculomotor, “prefrontal” and “limbic” functions
(1991) · Progress in Brain Research · doi:10.1016/s0079-6123(08)62678-3 · Cited by 1,961
Selective and divided attention during visual discriminations of shape, color, and speed: functional anatomy by positron emission tomography
Corbetta, M., Miezin, F. M., Dobmeyer, S., Shulman, G. L., & Petersen, S. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-08-02383.1991 · Cited by 1,590
Dissociation in prefrontal cortex of affective and attentional shifts
Dias, R., Robbins, T. W., & Roberts, A. C. (1996) · Nature · doi:10.1038/380069a0 · Cited by 1,527
The Return of Phineas Gage: Clues About the Brain from the Skull of a Famous Patient
Damásio, H., Grabowski, T. J., Frank, R. J., Galaburda, A. M., & Damásio, A. R. (1994) · Science · doi:10.1126/science.8178168 · Cited by 1,520
Word fluency and brain damage
Borkowski, J. G., Benton, A. L., & Spreen, O. (1967) · Neuropsychologia · doi:10.1016/0028-3932(67)90015-2 · Cited by 1,324

Show all 72 references

Research works printed but not linked: 5

Dolan R.J., 1991, J Cereb Blood Flow Metab, 67, S654
Drevets W.C., 1992, Psychopharmac Bull, 28, 261
Dupont R.M., 1990, Clinical and neuropsychological significance. Arch Gen Psychiat, 47, 55
Mayberg H.S., 1994, J Nucl Med, 35, 929
Starkstein S.E., 1995, Neuropsychiat, Neuropsychol Behav Neurol, 8, 38

Sorted by citations

Cognitive deficits in depression: Possible implications for functional neuropathology
Austin, M.-P., Mitchell, P., & Goodwin, G. M. (2001) · British Journal of Psychiatry · doi:10.1192/bjp.178.3.200 · Cited by 1,154
Self-citation
A meta-analysis of depression severity and cognitive function
McDermott, L. M., & Ebmeier, K. P. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.04.022 · Cited by 956
The role of the hippocampus in the pathophysiology of major depression
Campbell, S., & MacQUEEN, G. M. (2004) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0441 · Cited by 891
Increased Amygdala and Decreased Dorsolateral Prefrontal BOLD Responses in Unipolar Depression: Related and Independent Features
Siegle, G. J., Thompson, W., Carter, C. S., Steinhauer, S. R., & Thase, M. E. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.048 · Cited by 857
Chronic stress, cognitive functioning and mental health
Marin, M.-F., Lord, C., Andrews, J., Juster, R.-P., Sindi, S., Arsenault-Lapierre, G., Fiocco, A. J., & Lupien, S. J. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.02.016 · Cited by 654
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
Millan, M. J. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.11.006 · Cited by 569
Apathy in Parkinson's disease: clinical features, neural substrates, diagnosis, and treatment
Pagonabarraga, J., Kulisevsky, J., Strafella, A. P., & Krack, P. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00019-8 · Cited by 592
Executive and prefrontal dysfunction in unipolar depression: a review of neuropsychological and imaging evidence
Rogers, M. A., Kasai, K., Koji, M., Fukuda, R., Iwanami, A., Nakagome, K., Fukuda, M., & Kato, N. (2004) · Neuroscience Research · doi:10.1016/j.neures.2004.05.003 · Cited by 489
Bonsai trees in your head: how the pavlovian system sculpts goal-directed choices by pruning decision trees
Huys, Q. J. M., Eshel, N., O'Nions, E., Sheridan, L., Dayan, P., & Roiser, J. P. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002410 · Cited by 439
Neurobehavioral therapies in the 21st century: Summary of an emerging field and an extended example of Cognitive Control Training for depression
Siegle, G. J., Ghinassi, F., & Thase, M. E. (2007) · Cognitive Therapy and Research · doi:10.1007/s10608-006-9118-6 · Cited by 444
Executive Dysfunction in Geriatric Depression
Lockwood, K. A., Alexopoulos, G. S., & van Gorp, W. G. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.7.1119 · Cited by 378
The neuropathology of primary mood disorder
Harrison, P. J. (2002) · Brain · doi:10.1093/brain/awf149 · Cited by 325
Decision-making cognition in mania and depression
MURPHY, F. C., RUBINSZTEIN, J. S., MICHAEL, A., ROGERS, R. D., ROBBINS, T. W., PAYKEL, E. S., & SAHAKIAN, B. J. (2001) · Psychological Medicine · doi:10.1017/s0033291701003804 · Cited by 316
Cognitive function in depression: a distinct pattern of frontal impairment in melancholia?
Austin, M., Mitchell, P. B., Wilhelm, K. A., Parker, G. B., Hickie, I. B., Brodaty, H., CHAN, J., Eyers, K., MILIC, M., & Hadži-Pavlović, D. (1999) · Psychological Medicine · doi:10.1017/s0033291798007788 · Cited by 298
Serotonin 5-HT2C Receptors as a Target for the Treatment of Depressive and Anxious States: Focus on Novel Therapeutic Strategies
Millan, M. J. (2005) · Therapies · doi:10.2515/therapie:2005065 · Cited by 296
A Neuropsychological Investigation of Prefrontal Cortex Involvement in Acute Mania
Clark, L., Iversen, S. D., & Goodwin, G. M. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.10.1605 · Cited by 279
Self-citation
The neurobiology of depression in later-life: Clinical, neuropsychological, neuroimaging and pathophysiological features
Naismith, S. L., Norrie, L. M., Mowszowski, L., & Hickie, I. B. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.05.009 · Cited by 282
Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression
MICHAEL, N., Erfurth, A., Ohrmann, P., Arolt, V., Heindel, W. L., & Pfleiderer, B. (2003) · Psychological Medicine · doi:10.1017/s0033291703007931 · Cited by 260
Cognitive and neurological impairment in mood disorders
Marvel, C. L., & Paradiso, S. (2004) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(03)00106-0 · Cited by 268
Where is Cingulate Cortex? A Cross-Species View
van Heukelum, S., Mars, R. B., Guthrie, M., Buitelaar, J. K., Beckmann, C. F., Tiesinga, P. H. E., Vogt, B. A., Glennon, J. C., & Havenith, M. N. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.03.007 · Cited by 262
The cognitive neuropsychology of depression in the elderly
Herrmann, L. L., Goodwin, G. M., & Ebmeier, K. P. (2007) · Psychological Medicine · doi:10.1017/s0033291707001134 · Cited by 250
Self-citation
Executive functioning in depressed patients with suicidal ideation
Marzuk, P. M., Hartwell, N., Leon, A. C., & Portera, L. (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00585.x · Cited by 262
Neuropsychological Impairment in Major Depression: Its Nature, Origin and Clinical Significance
Porter, R. J., Bourke, C., & Gallagher, P. (2007) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/00048670601109881 · Cited by 236
Reciprocal autoreceptor and heteroreceptor control of serotonergic, dopaminergic and noradrenergic transmission in the frontal cortex: relevance to the actions of antidepressant agents
Millan, M. J., Lejeune, F., & Gobert, A. (2000) · Journal of Psychopharmacology · doi:10.1177/026988110001400202 · Cited by 225
Abnormal regional spontaneous neural activity in treatment‐refractory depression revealed by resting‐state fMRI
Wu, Q., Li, D., Kuang, W., Zhang, T., Lui, S., Huang, X., Chan, R. C. K., Kemp, G. J., & Gong, Q. (2010) · Human Brain Mapping · doi:10.1002/hbm.21108 · Cited by 215
Frontal and Limbic Activation During Inhibitory Control Predicts Treatment Response in Major Depressive Disorder
Langenecker, S. A., Kennedy, S. E., Guidotti, L. M., Briceño, E. M., Own, L. S., Hooven, T. A., Young, E. A., Akil, H., Noll, D. C., & Zubieta, J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.02.019 · Cited by 215
Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatment
Elizalde, N., Gil-Bea, F. J., Ramírez, M. J., Aisa, B., Lasheras, B., del Rı́o, J. A., & Tordera, R. M. (2008) · Psychopharmacology · doi:10.1007/s00213-007-1035-1 · Cited by 206
Behavioural and neurocognitive responses to sad facial affect are attenuated in patients with mania
LENNOX, B. R., JACOB, R., CALDER, A. J., LUPSON, V., & BULLMORE, E. T. (2004) · Psychological Medicine · doi:10.1017/s0033291704002557 · Cited by 192
An fMRI study of prefrontal brain activation during multiple tasks in patients with major depressive disorder
Fitzgerald, P. B., Srithiran, A., Mendieta, J. B., Daskalakis, Z., Oxley, T. J., Kulkarni, J., & Egan, G. F. (2007) · Human Brain Mapping · doi:10.1002/hbm.20414 · Cited by 194
A meta-analysis of the effects of antidepressants on cognitive functioning in depressed and non-depressed samples
Prado, C. E., Watt, S., & Crowe, S. F. (2018) · Neuropsychology Review · doi:10.1007/s11065-018-9369-5 · Cited by 188
Impairment across executive functions in recurrent major depression
Stordal, K. I., Lundervold, A. J., Egeland, J., Mykletun, A., Asbjørnsen, A., Landrø, N. I., Roness, A., Rund, B. R., Sundet, K., Oedegaard, K. J., et al. (2004) · Nordic Journal of Psychiatry · doi:10.1080/08039480310000789 · Cited by 180
Event-related potentials (ERPs) to hemifield presentations of emotional stimuli: differences between depressed patients and healthy adults in P3 amplitude and asymmetry
Jürgen Kayser, A. (2000) · International Journal of Psychophysiology · doi:10.1016/s0167-8760(00)00078-7 · Cited by 180
Improving the Prediction of Treatment Response in Depression:Integration of Clinical, Cognitive, Psychophysiological, Neuroimaging, and Genetic Measures
Kemp, A. H., Gordon, E., Rush, A. J., & Williams, L. M. (2008) · CNS Spectrums · doi:10.1017/s1092852900017120 · Cited by 170
Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of α2‐adrenergic and serotonin2C receptors: a comparison with citalopram
Millan, M. J., Gobert, A., Rivet, J., Adhumeau-Auclair, A., Cussac, D., Newman‐Tancredi, A., Dekeyne, A., Nicolas, J., & Lejeune, F. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00982.x · Cited by 170
Cannabinoid receptors are localized to noradrenergic axon terminals in the rat frontal cortex
Oropeza, V. C., Mackie, K., & Bockstaele, E. J. V. (2006) · Brain Research · doi:10.1016/j.brainres.2006.09.110 · Cited by 150
Frontostriatal deficits in unipolar major depression
Rogers, M. A., Bradshaw, J. L., Pantelis, C., & Phillips, J. G. (1998) · Brain Research Bulletin · doi:10.1016/s0361-9230(98)00126-9 · Cited by 150
Repetitive Transcranial Magnetic Stimulation Treatment of Comorbid Posttraumatic Stress Disorder and Major Depression
Rosenberg, P. B., Mehndiratta, R. B., Mehndiratta, Y. P., Wamer, A., Rosse, R. B., & Balish, M. (2002) · Journal of Neuropsychiatry · doi:10.1176/jnp.14.3.270 · Cited by 145
Executive function improvement upon remission of recurrent unipolar depression
Biringer, E., Lundervold, A., Stordal, K., Mykletun, A., Egeland, J., Bottlender, R., & Lund, A. (2005) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-005-0577-7 · Cited by 138
Qualitative analysis of verbal fluency in depression
Fossati, P., Guillaume, L. B., Ergis, A.-M., & Allilaire, J. (2003) · Psychiatry Research · doi:10.1016/s0165-1781(02)00300-1 · Cited by 134
Volumetric analysis of the pre-frontal regions: findings in aging and schizophrenia
Convit, A. J., Wolf, O. T., de Leon, M. J., Patalinjug, M. B., Kandil, E., Caraos, C., Scherer, A., Louis, L. A. S., & Cancro, R. (2001) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(01)00097-x · Cited by 132
Cognitive deficits in the rat chronic mild stress model for depression: Relation to anhedonic-like responses
Henningsen, K., Andreasen, J. T., Bouzinova, E. V., Jayatissa, M. N., Jensen, M. S., Redrobe, J. P., & Wiborg, O. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.10.039 · Cited by 130
Neurobiological mechanisms in generalized anxiety disorder.
Nutt, D. J. (2001) · PubMed · Cited by 123
Generalized anxiety disorder: comorbidity, comparative biology and treatment
Nutt, D., Ballenger, J. C., Sheehan, D. V., & Wïttchen, H. (2002) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145702003048 · Cited by 129
The neuropsychological profile in unipolar depression
Elliott, R. (1998) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(98)01235-2 · Cited by 176
Electrical Stimulation of Rat Medial Prefrontal Cortex Enhances Forebrain Serotonin Output Implications for Electroconvulsive Therapy and Transcranial Magnetic Stimulation in Depression
Juckel, G. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00097-9 · Cited by 112
Brain Network Dysfunction in Late-Life Depression
Tadayonnejad, R., & Ajilore, O. (2013) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988713516539 · Cited by 124
Lesion pattern in patients with multiple sclerosis and depression
Berg, D., Supprian, T., Thomae, J., Warmuth‐Metz, M., Horowski, A., Zeiler, B., Magnus, T. U., Rieckmann, P., & Becker, G. (2000) · Multiple Sclerosis Journal · doi:10.1177/135245850000600304 · Cited by 114
Working memory dysfunction in major depression: an event-related potential study
Pelosi, L., Slade, T., Blumhardt, L. D., & Sharma, V. K. (2000) · Clinical Neurophysiology · doi:10.1016/s1388-2457(00)00354-0 · Cited by 112
Buspirone modulates basal and fluoxetine-stimulated dialysate levels of dopamine, noradrenaline and serotonin in the frontal cortex of freely moving rats: activation of serotonin1A receptors and blockade of α2-adrenergic receptors underlie its actions
Gobert, A., Rivet, J., Cistarelli, L., Melon, C., & Millan, M. J. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00211-0 · Cited by 103
Motor deficits and schizophrenia: the evidence from neuroleptic-naïve patients and populations at risk.
Wolff, A. L., & O’Driscoll, G. A. (1999) · PubMed Central · Cited by 103
Anatomical MRI study of corpus callosum in unipolar depression
Lacerda, A. L. T., Brambilla, P., Sassi, R. B., Nicoletti, M., Mallinger, A. G., Frank, E., Kupfer, D. J., Keshavan, M. S., & Soares, J. C. (2004) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2004.10.004 · Cited by 103
Differences in verbal memory retrieval in breast cancer chemotherapy patients compared to healthy controls: a prospective fMRI study
Zunini, R. A. L., Scherling, C., Wallis, N., Collins, B., MacKenzie, J., Bielajew, C. H., & Smith, A. (2012) · Brain Imaging and Behavior · doi:10.1007/s11682-012-9213-0 · Cited by 101
Anterior cingulate cortex gray matter abnormalities in adults with attention deficit hyperactivity disorder: a voxel-based morphometry study
Amico, F., Stauber, J., Koutsouleris, N., & Frodl, T. (2011) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2010.08.011 · Cited by 98
Efficacy of high frequency (rapid) suprathreshold repetitive transcranial magnetic stimulation of right prefrontal cortex in bipolar mania: A randomized sham controlled study
Praharaj, S. K., Ram, D., & Arora, M. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.12.020 · Cited by 98
The prefrontal–limbic network in depression: Modulation by hypothalamus, basal ganglia and midbrain
Bennett, M. R. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.01.006 · Cited by 98
Depression severity is correlated to the integrity of white matter fiber tracts in late-onset major depression
Dalby, R. B., Frandsen, J., Chakravarty, M. M., Ahdidan, J., Sørensen, L., Rosenberg, R., Videbech, P., & Østergaard, L. (2010) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2010.06.008 · Cited by 96
Childhood Trauma and PTSD Symptoms Increase the Risk of Cognitive Impairment in a Sample of Former Indentured Child Laborers in Old Age
Burri, A. V., Maercker, A. R. A., Krammer, S., & Simmen‐Janevska, K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057826 · Cited by 97
Effects of Acute and Chronic Reboxetine Treatment on Stress-induced Monoamine Efflux in the Rat Frontal Cortex
Page, M. E. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00301-9 · Cited by 90
The clinical effectiveness and cost of repetitive transcranial magnetic stimulation versus electroconvulsive therapy in severe depression: a multicentre pragmatic randomised controlled trial and economic analysis.
McLoughlin, D., Mogg, A., Eranti, S., Pluck, G., Purvis, R., Edwards, D., Landau, S., Brown, R. G., Rabe-Heskith, S., Howard, R., et al. (2007) · Health Technology Assessment · doi:10.3310/hta11240 · Cited by 93
Pseudo-dementia: A neuropsychological review
Prakash, R., Kang, H., Zhao, F., You, L., Giorgetta, C., Venkatesh, D., & Sarkhel, S. (2014) · Annals of Indian Academy of Neurology · doi:10.4103/0972-2327.132613 · Cited by 91
Long-lasting cognitive impairment in unipolar major depression: a 6-month follow-up study
Hammar, Å., Lund, A., & Hugdahl, K. (2003) · Psychiatry Research · doi:10.1016/s0165-1781(03)00075-1 · Cited by 88
Cerebral perfusion in chronic fatigue syndrome and depression
MacHale, S., Lawrie, S. M., Cavanagh, J., Glabus, M. F., Murray, C. L., Ebmeier, K. P., & Goodwin, G. M. (2000) · The British Journal of Psychiatry · doi:10.1192/bjp.176.6.550 · Cited by 88
Self-citation
Localization of white-matter lesions and effect of vascular risk factors in late-onset major depression
Dalby, R. B., Chakravarty, M. M., Ahdidan, J., Sørensen, L. U., Frandsen, J. R., Jónsdóttir, K. Ý., Tehrani, E., Rosenberg, R., Østergaard, L., & Videbech, P. (2009) · Psychological Medicine · doi:10.1017/s0033291709991656 · Cited by 85
Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups
Baek, S., Jun, T.-W., Kim, K.-J., Shin, M., Kang, S.-Y., & Kim, C. (2011) · Brain and Development · doi:10.1016/j.braindev.2011.01.011 · Cited by 84
Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood
O’Malley, D., Dinan, T. G., & Cryan, J. F. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1885-9 · Cited by 82
Effects of a single dose of cortisol on the neural correlates of episodic memory and error processing in healthy volunteers
Hsu, F., Garside, M. J., Massey, A. E., & McAllister-Williams, H. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1413-2 · Cited by 78
High-frequency repetitive transcranial magnetic stimulation delays rapid eye movement sleep
Cohrs, S., Tergau, F., Riech, S., Kästner, S., Paulus, W., Ziemann, U., Rüther, E., & Hajak, G. (1998) · Neuroreport · doi:10.1097/00001756-199810260-00019 · Cited by 74
Subtypes of Memory Dysfunction Associated with ECT: Characteristics and Neurobiological Bases
Rami-González, L., Bernardo, M., Boget, T., Salamero, M., Gil-Verona, J. A., & Junqué, C. (2001) · Journal of Ect · doi:10.1097/00124509-200106000-00008 · Cited by 73
Lack of insight may predict impaired decision making in manic patients
Adida, M., Clark, L., Mazzola‐Pomietto, P., Kaladjian, A., Besnier, N., Azorin, J., Jeanningros, R., & Goodwin, G. M. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00618.x · Cited by 75
Self-citation
Impact of Work Environment and Occupational Stress on Safety Behavior of Individual Construction Workers
Jung, M., Lim, S., & Chi, S. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17228304 · Cited by 88
Suicidal Behaviours in Affective Disorders: A Defcit of Cognitive Inhibition?
Richard‐Devantoy, S., Gorwood, P. A. P. M., Annweiler, C., Olié, J., Gall, D. L., & Beauchet, O. (2012) · The Canadian Journal of Psychiatry · doi:10.1177/070674371205700409 · Cited by 70
Modulation of Dialysate Levels of Dopamine, Noradrenaline, and Serotonin (5-HT) in the Frontal Cortex of Freely-Moving Rats by (-)-Pindolol Alone and in Association with 5-HT Reuptake Inhibitors Comparative Roles of β-Adrenergic, 5-HT1A, and 5-HT1B Receptors
Gobert, A. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00035-4 · Cited by 70
Changes in regional cerebral blood flow following antidepressant treatment in late‐life depression
Ishizaki, J., Yamamoto, H., Takahashi, T., Takeda, M., Yano, M., & Mimura, M. (2008) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1980 · Cited by 68
Residual cognitive impairment in late‐life depression after a 12‐month period follow‐up
Portella, M. J., Marcos, T., Rami, L., Navarro, V., Gastó, C., & Salamero, M. (2003) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.895 · Cited by 67
Abnormalities in P300 components in depression: an ERP-sLORETA study
Zhou, L., Wang, G., Cai, N., Wang, H., Liu, Z., & Bai, H. (2019) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2018.1478991 · Cited by 67
Neuropsychological and hypothalamic–pituitary-axis function in female patients with melancholic and non-melancholic depression
Michopoulos, I., Zervas, I. M., Pantelis, C., Tsaltas, E., Papakosta, V., Boufidou, F., Nikolaou, C., Papageorgiou, C., Soldatos, C. R., & Lykouras, L. (2008) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-007-0781-8 · Cited by 62
Neuroanatomical studies on bipolar disorder
Baumann, B., & Bogerts, B. (2001) · The British Journal of Psychiatry · doi:10.1192/bjp.178.41.s142 · Cited by 60
Major and minor depression in Parkinson's disease: a neuropsychological investigation
da Costa, A. L. C., Peppe, A., Carlesimo, G. A., Pasqualetti, P., & Caltagirone, C. (2006) · European Journal of Neurology · doi:10.1111/j.1468-1331.2006.01406.x · Cited by 62
Cognitive Function in Patients with Multiple Sclerosis: Impairment and Treatment
Rao, S. M. (2004) · International Journal of MS Care · doi:10.7224/1537-2073-6.1.9 · Cited by 58
Decrease in genu of the corpus callosum in medication-naïve, early-onset dysthymia and depressive personality disorder
Lyoo, I. K., Kwon, J. S., Lee, S., Han, M. H., Chang, C.-G., Seo, C. S., Lee, S. I. K., & Renshaw, P. F. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01436-1 · Cited by 59
Depression: a role for neurosurgery?
Malhi, J. R. B. G. S. (2000) · British Journal of Neurosurgery · doi:10.1080/02688690050175193 · Cited by 56
Local administration of a cannabinoid agonist alters norepinephrine efflux in the rat frontal cortex
Page, M. E., Oropeza, V. C., & Bockstaele, E. J. V. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.11.009 · Cited by 55
Neurocognitive dysfunction in antidepressant-free, non-elderly patients with unipolar depression: Alerting and covert orienting of visuospatial attention
Pardo, J. V., Pardo, P. J., Humes, S. W., & Posner, M. I. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.12.037 · Cited by 53
Abnormal brain activation during directed forgetting of negative memory in depressed patients
Yang, W., Chen, Q., Liu, P., Cheng, H., Cui, Q., Wei, D., Zhang, Q., & Qiu, J. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.05.034 · Cited by 55
Is poststroke depression a vascular depression?
Diéguez, S., Staub, F., Bruggimann, L., & Bogousslavsky, J. (2004) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2004.09.012 · Cited by 54
Psychosocial factors and ageing in older lesbian, gay and bisexual people: a systematic review of the literature
McParland, J., & Camic, P. M. (2016) · Journal of Clinical Nursing · doi:10.1111/jocn.13251 · Cited by 61
The Danish PET/depression project: poor verbal fluency performance despite normal prefrontal activation in patients with major depression
Videbech, P., Ravnkilde, B., Kristensen, S., Egander, A., Clemmensen, K., Rasmussen, N. A., GJEDDE, A. H., & Rosenberg, R. (2003) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(03)00002-7 · Cited by 50
Memory and Metamemory Functioning Among Depressed Patients
Kalska, H., Punamäki, R., Makinen-Pelli, T., & Saarinen, M. (1999) · Applied Neuropsychology · doi:10.1207/s15324826an0602_5 · Cited by 49
Perspectives of B-Mode Transcranial Ultrasound
Berg, D., & Becker, G. (2002) · NeuroImage · doi:10.1006/nimg.2001.1014 · Cited by 47
Simultaneous analyses of the neurochemical and behavioral effects of the norepinephrine reuptake inhibitor reboxetine in a rat model of antidepressant action
Page, M. E., Brown, K., & Lucki, I. (2003) · Psychopharmacology · doi:10.1007/s00213-002-1269-x · Cited by 44
A psychopathological study into the relationship between attention deficit hyperactivity disorder in adult patients and recurrent brief depression
Heßlinger, B., van Elst, L. T., Mochan, F., & Ebert, D. (2003) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2003.00112.x · Cited by 44
Depression and neurological disorders
Benedetti, F., Bernasconi, A., & Pontiggia, A. (2005) · Current Opinion in Psychiatry · doi:10.1097/01.yco.0000194147.88647.7f · Cited by 45
Neurocognitive functioning in bipolar depression: a component structure analysis
Gallagher, P., Gray, J. M., Watson, S., Young, A. H., & Ferrier, I. N. (2013) · Psychological Medicine · doi:10.1017/s0033291713001487 · Cited by 45
Salivary cortisol patterns and cognitive speed in major depression: a comparison with allergic rhinitis and healthy control subjects
Hartog, H. M. D., Nicolson, N. A., Derix, M. M. A., van Bemmel, A. L., Kremer, B., & Jolles, J. (2003) · Biological Psychology · doi:10.1016/s0301-0511(03)00050-4 · Cited by 41
Prefrontal cortex modulation of mood and emotionally induced facial expressions: a transcranial magnetic stimulation study.
Padberg, F., Juckel, G., Präßl, A., Zwanzger, P., Mavrogiorgou, P., Hegerl, U., Hampel, H., & Möller, H. (2001) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.13.2.206 · Cited by 48
The postconcussion syndrome after mild head trauma: is brain damage overdiagnosed? Part 1.
Margulies, S. L. (2000) · Journal of clinical neuroscience · doi:10.1054/jocn.1999.0681 · Cited by 45
Neuropsychological effects of stress on social phobia with and without comorbid depression
Graver, C. J., & White, P. M. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2006.08.002 · Cited by 39
Apathy in Parkinson's Disease
Pagonabarraga, J., & Kulisevsky, J. (2017) · International review of neurobiology · doi:10.1016/bs.irn.2017.05.025 · Cited by 40
Effects of repeated cortisol administration on brain potential correlates of episodic memory retrieval
McAllister-Williams, H., & Rugg, M. D. (2002) · Psychopharmacology · doi:10.1007/s00213-001-0938-5 · Cited by 39
Neuropsychological Function in Patients With Chronic Fatigue Syndrome, Multiple Sclerosis, and Depression
Daly, E., Komaroff, A. L., Bloomingdale, K. L., Wilson, S. J., & Albert, M. (2001) · Applied Neuropsychology · doi:10.1207/s15324826an0801_3 · Cited by 38

Authors: Goodwin, G. M.
Affiliations: Warneford Hospital (GB)
Corresponding author: Goodwin, Guy M.
ORCID: Goodwin, Guy M.
Venue: Journal of Psychopharmacology
Publisher: SAGE Publications
Published: 1997-03
Volume: 11
Issue: 2
Pages: 115-122
ISSN: 0269-8811 (ISSN-L)
1461-7285
DOI: 10.1177/026988119701100204
OpenAlex: W2141880924
Cited by: 199
References: 72
Citations by year: 2025: 1 · 2024: 1 · 2023: 4 · 2022: 2 · 2021: 4 · 2020: 7 · 2019: 5 · 2018: 2 · 2017: 5 · 2016: 3 · 2015: 4 · 2014: 6 · 2013: 9 · 2012: 9
FWCI: 4.30
Type: journal article
Language: en
Open access: closed
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of Psychopharmacology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: major depressive disorder, frontal lobe, frontostriatal circuits, cognitive impairment, memory impairment, older adults, cerebral hypoperfusion, cingulate cortex, neuromodulation, structural brain abnormalities, neuropsychological assessment, neuroimaging
MeSH terms: Affect, Brain Mapping, Dementia, Depressive Disorder, Energy Metabolism, Frontal Lobe, Gyrus Cinguli, Humans, Neuropsychological Tests, Regional Blood Flow, Tomography, Emission-Computed, Tomography, Emission-Computed, Single-Photon, Prefrontal Cortex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks