The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Treating Nonsuicidal Self-Injury: A Systematic Review of Psychological and Pharmacological Interventions
Open accessAbstract
Objective: Nonsuicidal self-injury (NSSI), the deliberate, self-inflicted damage of bodily tissue without the intent to die, is associated with various negative outcomes. Although basic and epidemiologic research on NSSI has increased during the last 2 decades, literature on effective interventions targeting NSSI is still emerging. Here, we present a comprehensive, systematic review of existing psychological and pharmacological treatments designed specifically for NSSI, or including outcome assessments examining change in NSSI. Method: We conducted a systematic search of PsycINFO, MEDLINE, and ERIC databases to retrieve relevant articles that met inclusion criteria; specifically, uncontrolled and controlled trials that 1) presented quantitative outcome data on NSSI, and 2) clearly differentiated NSSI from suicidal self-injury (SSI). Consistent with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, definition of NSSI, we excluded studies examining populations with developmental or intellectual disabilities, or with psychotic disorders. Results: Several interventions appear to hold promise for reducing NSSI, including dialectical behaviour therapy, emotion regulation group therapy, manual-assisted cognitive therapy, dynamic deconstructive psychotherapy, atypical antipsychotics (aripiprazole), naltrexone, and selective serotonin reuptake inhibitors (with or without cognitive-behavioural therapy). Nevertheless, there remains a paucity of well-controlled studies investigating treatment efficacy for NSSI. Conclusions: Structured psychotherapeutic approaches focusing on collaborative therapeutic relationships, motivation for change, and directly addressing NSSI behaviours seem to be most effective in reducing NSSI. Medications targeting the serotonergic, dopaminergic and opioid systems also have demonstrated some benefits. Future studies employing controlled designs as well as a clear delineation of NSSI and SSI will improve knowledge regarding treatment effects.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“In their systematic review of non-suicidal self-injury, Turner et al. (2014) concluded that structure and collaboration were the most effective components of treatment, but did not identify a clear front runner in psychological interventions.”
From A multi‐method evaluation of a compassion‐focused cognitive behavioural psychotherapy group for people who self‐harm. (2022) · cites this paper as Turner et al. (2014)
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
J Neuropsychiatry Clin Neurosci
Yudofsky, S. C., & Hales, R. E. (1992) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.4.4.359 · Cited by 3,818
Defining empirically supported therapies.
Chambless, D. L., & Hollon, S. D. (1998) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.66.1.7 · Cited by 3,067
Cognitive-behavioral treatment of chronically parasuicidal borderline patients
Linehan, M. M. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810360024003 · Cited by 2,203
Linehan, M. M., Comtois, K. A., Murray, A. M., Brown, M. Z., Gallop, R. J., Heard, H. L., Korslund, K. E., Tutek, D. A., Reynolds, S. K., & Lindenboim, N. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.7.757 · Cited by 2,025
Nock, M. K. (2010) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.121208.131258 · Cited by 1,550
Dialectical behavior therapy for patients with borderline personality disorder and drug dependence
Linehan, M. M., Schmidt, H., Dimeff, L. A., Craft, J. C., Kanter, J., & Comtois, K. A. (1999) · The American Journal on Addictions · doi:10.1080/105504999305686 · Cited by 1,043
Evaluating three treatments for borderline personality disorder: a multiwave study
Clarkin, J. F., Levy, K. N., Lenzenweger, M. F., & Kernberg, O. F. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.6.922 · Cited by 997
Silverman, M. M., Berman, A. L., Sanddal, N. D., O'Carroll, P. W., & Joiner, T. E. (2007) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.2007.37.3.264 · Cited by 991
Linehan, M. M., Dimeff, L. A., Reynolds, S. K., Comtois, K. A., Welch, S. S., Heagerty, P., & Kivlahan, D. R. (2002) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00011-x · Cited by 741
McMain, S. F., Links, P. S., Gnam, W. H., Guimond, T., Cardish, R. J., Korman, L., & Streiner, D. L. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09010039 · Cited by 729
Research works printed but not linked: 85
- International Society for the Study of Self-Injury, 2007, Definition of non-suicidal self-injury [Internet]
- 10.1176/appi.books.9780890425596 · DOI · Paper page
- 10.1080/15374416.2013.794699 · DOI
- 10.1037/a0024405 · DOI
- 10.1037/h0080369 · DOI
- 10.1017/S0033291710002497 · DOI
- 10.1177/0272431608316604 · DOI
- 10.1007/s10964-005-7262-z · DOI · Paper page
- 10.1521/suli.34.1.12.27769 · DOI · Paper page
- 10.1023/A:1014089117419 · DOI
- 10.1007/s10802-013-9712-5 · DOI
- 10.1046/j.1440-1819.2003.01088.x · DOI
- 10.1080/15374410801955771 · DOI
- 10.1037/0022-006X.72.5.885 · DOI
- 10.1186/1753-2000-6-14 · DOI
- 10.1037/0003-066X.57.12.1052 · DOI
- 10.17744/mehc.28.2.6w61cut2lxjdg3m7 · DOI
- 10.1016/j.psychres.2010.03.019 · DOI
- 10.1017/S003329170700027X · DOI
- 10.1016/j.psychres.2006.05.010 · DOI · Paper page
- 10.1176/appi.ajp.2010.10050718 · DOI · Paper page
- 10.1176/ajp.151.9.1305 · DOI · Paper page
- 10.1111/j.1600-0447.1989.tb10259.x · DOI
- 10.1027/0227-5910.27.1.4 · DOI
- O'Carroll PW, 1998, Suicide prevention: The global context, 23
- 10.1037/0021-843X.111.1.198 · DOI · Paper page
- 10.1037/0002-9432.75.2.324 · DOI
- Walsh BW, 2006, Treating self-injury: A practical guide
- 10.1111/j.1467-8721.2009.01613.x · DOI
- Plener PL, 2009, Self-injury in youth: The essential guide to assessment and intervention, 275
- 10.1037/11875-015 · DOI
- 10.1891/0889-8391.26.1.3 · DOI
- 10.1111/jcap.12035 · DOI
- 10.3122/jabfm.2010.02.090110 · DOI
- 10.1016/S0272-7358(97)00105-0 · DOI
- 10.1521/suli.31.2.169.21516 · DOI
- 10.1016/j.jaac.2013.09.009 · DOI
- 10.1002/jclp.20418 · DOI
- 10.1016/S0140-6736(04)16770-6 · DOI · Paper page
- 10.1007/s10567-012-0126-7 · DOI
- 10.1002/jclp.20415 · DOI
- 10.1027/0227-5910/a000060 · DOI
- 10.1111/j.1469-7610.2012.02525.x · DOI
- 10.1017/S0033291701004238 · DOI
- 10.1177/1059840510388570 · DOI
- Linehan MM, 2014, Research on dialectical behavior therapy: Summary of the data to date [Internet]
- US Preventive Services Task Force, 1996, Guide to clinical preventive services
- Linehan MM, 1993, Skills training manual for treating borderline personality disorder
- Linehan MM, 1993, Cognitive-behavioral treatment of borderline personality disorder
- 10.1002/eat.22112 · DOI
- 10.1155/2013/145219 · DOI
- 10.1111/j.1475-3588.2010.00569.x · DOI · Paper page
- Van Goethem A, 2012, Rev Int Psicol Ter Psicol = International Journal of Psychology & Psychological Therapy, 12, 21
- 10.1037/a0029096 · DOI
- 10.1192/bjp.182.2.135 · DOI
- 10.1891/0889-8391.26.4.365 · DOI
- 10.1017/S003329179800765X · DOI
- 10.1521/pedi.2006.20.5.482 · DOI
- Newham P., 1994, The singing cure: An introduction to voice movement therapy
- 10.1177/1943862112467649 · DOI
- 10.1001/archpsyc.1985.01790340059009 · DOI
- 10.1177/00030651090570011006 · DOI
- Clarkin JF, 2006, Psychotherapy for borderline personality: Focusing on object relations
- 10.1521/pedi.15.6.487.19190 · DOI
- 10.1001/archpsyc.63.6.649 · DOI · Paper page
- 10.1176/ajp.2006.163.5.833 · DOI
- 10.1007/s00213-007-0740-0 · DOI
- 10.1521/capn.2005.10.4.1 · DOI
- 10.1097/00005053-199603000-00011 · DOI
- 10.1176/ajp.148.8.1064 · DOI
- Markovitz PJ, 1995, Psychopharmacol Bull, 31, 773
- Roth AS, 1996, J Clin Psychiatry, 57, 233
- 10.1176/appi.ajp.2008.08070976 · DOI · Paper page
- 10.4088/JCP.v69n0617 · DOI
- 10.1080/10398560701317101 · DOI
- 10.1192/bjp.bp.109.067199 · DOI
- 10.1176/appi.psychotherapy.2009.63.1.41 · DOI
- Nixon MK, 2003, Can Child Adolesc Psychiatry Rev, 12, 10
- 10.1037/a0026113 · DOI
- 10.1016/j.brat.2005.03.005 · DOI · Paper page
- 10.1016/j.brat.2010.05.017 · DOI · Paper page
- 10.1037/a0025043 · DOI
- 10.1521/capn.2005.10.6.1 · DOI
- 10.1001/archpsyc.62.10.1122 · DOI
- Moher D, 2009, PLoS Med, 6
Cited by
Sorted by citations
Items 101–200 of 219
Barca, L., Maisto, D., & Pezzulo, G. (2023) · Neuroscience of Consciousness · doi:10.1093/nc/niad025 · Cited by 10
Drubina, B., Kökönyei, G., & Reinhardt, M. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03408-7 · Cited by 10
“Structured psychotherapeutic approaches that focus on collaborative therapeutic relationships and motivation for change while directly keeping in focus the NSSI behavior itself seem to be the most effective in reducing NSSI [76].”
BackgroundOlsen, M. H., Morthorst, B. R., Pagsberg, A. K., Heinrichsen, M., Møhl, B., Rubæk, L., Bjureberg, J., Simonsson, O., Lindschou, J., Gluud, C. N., et al. (2021) · Trials · doi:10.1186/s13063-021-05406-2 · Cited by 13
The Role of Pleasure Neurobiology and Dopamine in Mental Health Disorders.
Worley, J. A. (2017) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/02793695-20170818-09 · Cited by 9
A Study of Spontaneous Self-Injurious Behavior and Neuroimaging in Rhesus Macaques
Zhang, Y., Qiao, Y.-C., Ji, Y., Huang, H., Zhang, L., Ruan, J.-X., Li, C., Xie, H., Zhang, B.-L., Zhou, Q., et al. (2025) · Research · doi:10.34133/research.0782 · Cited by 3
“Dopamine is implicated in NSSI-related psychiatric mechanisms [ 31 ].”
Ye, Z., Zhang, F., Cui, R., Ye, X., Tan, M., Tao, T., & Zhang, X. (2024) · BMC Psychology · doi:10.1186/s40359-024-02236-0 · Cited by 11
Liu, C., Ye, X., & Chen, M. (2024) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.13132 · Cited by 10
“In addition to structured psychotherapeutic approaches focusing on collaborative therapeutic relationships and motivation for change to reduce NSSI among depressed adolescents, medications targeting depressive symptoms also have demonstrated some benefits (Turner et al., 2014).”
Li, X.-T., Liu, S.-Y., Tian, Y.-S., He, J., Chen, H., Ning, M., Chen, Z.-Y., Yang, J.-X., Li, Y., & Zhou, J.-S. (2023) · BMC Nursing · doi:10.1186/s12912-023-01542-z · Cited by 8
“Till now, there are no specific psychopharmacological treatment for NSSI, medications such as fluoxetine and aripiprazole are only used for treatment the comorbid mental disorders [10].”
BackgroundMorthorst, B. R., Rubæk, L., Lindschou, J., Jakobsen, J. C., Gluud, C. N., Bjureberg, J., Hellner, C., Møhl, B., & Pagsberg, A. K. (2021) · Pilot and Feasibility Studies · doi:10.1186/s40814-021-00785-4 · Cited by 11
Rayner, G. C., Bowling, G., Bluff, L., Wright, K., Ashworth‐Lord, A., & Laird, C. (2022) · Counselling and Psychotherapy Research · doi:10.1002/capr.12516 · Cited by 7
Losaberidze, M., Mallorquí‐Bagué, N., Demetrovics, Z., Jiménez‐Múrcia, S., Potenza, M. N., Soborun, Y., Romero, P., Reinhardt, M., Kökönyei, G., Mestre‐Bach, G., et al. (2025) · Journal of Behavioral Addictions · doi:10.1556/2006.2025.00079 · Cited by 9
Turner, C. J., & Chapman, A. L. (2025) · Personality and Mental Health · doi:10.1002/pmh.1640 · Cited by 8
“To date, treatments that address emotion regulation as a core mechanism of change have shown promise in the treatment of NSSI within and outside of BPD (Berk et al., 2020; Cook & Gorraiz, 2016; Turner et al., 2014).”
Self-citationMithani, K., Zhang, K., Yan, H., Elkaim, L. M., Gariscsak, P. J., Suresh, H., Gouveia, F., Fasano, A., Gorodetsky, C., & Ibrahim, G. M. (2024) · Neuromodulation (Malden, Mass.) · doi:10.1016/j.neurom.2024.07.009 · Cited by 7
Orsolini, L., Corona, D., Cervelli, A. L., Ribuoli, E., Longo, G., & Volpe, U. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1403038 · Cited by 7
“Reported data sums up to a relatively high prevalence in this population, estimated to be 16% (4), and, as such, NSSI is identi fi ed as a major public health concern (5, 6), even more so as it associates with different negative outcomes, including suicidal behaviours (7).”
BackgroundPediatric suicide: Review of a preventable tragedy
Greydanus, D. E., Nazeer, A., Qayyum, Z., Patel, D. R., Rausch, R., Hoang, L.-N., Miller, C., Chahin, S. S., Apple, R. W., Saha, G. K., et al. (2024) · Disease-a-Month · doi:10.1016/j.disamonth.2024.101725 · Cited by 10
Efficacy and Safety of Aripiprazole in Borderline Personality Disorder: A Systematic Review
Valdivieso-Jiménez, G., Pino-Zavaleta, D. A., Campos-Rodriguez, S. K., Ortiz-Saavedra, B., Fernández, M. F., & Benites-Zapata, V. (2023) · Psychiatric quarterly · doi:10.1007/s11126-023-10045-8 · Cited by 7
“Similarly, additional systematic reviews on pharmacological treatment for BPD that used the same study by Nickel et al. [25, 26] reached the same conclusion about the insufficient evidence for using aripiprazole and produced the same results [29–32].”
ResultTreating Adolescent Non-Suicidal Self-Injury: Guidelines for Clinical Practice
Flaherty, H. B. (2021) · Child & Youth Services · doi:10.1080/0145935x.2021.1938525 · Cited by 10
“Despite the prevalence and seriousness of NSSI, there is currently no universally agreed-upon best practice for the treatment of NSSI (Flaherty, 2018; King et al., 2020; Klonsky & Muehlenkamp, 2007; Muehlenkamp, 2006; Nock, 2012; Ose et al., 2021; Turner et al., 2014).”
BackgroundPotential relationship of self-injurious behavior to right temporo-parietal lesions
Borah, S., McConnell, B., Hughes, R., & Kluger, B. M. (2016) · Neurocase · doi:10.1080/13554794.2016.1147586 · Cited by 7
Liu, P., Li, B. Y., Liu, J., Yang, X., Li, Y., Li, Y., & Lu, J. (2025) · BMC Psychology · doi:10.1186/s40359-025-03151-8 · Cited by 6
“…(ERITA) [8], Treatment for Self-Injurious Behaviors (T-SIB) [9] and Intensive Contextual Treatment (ICT) [10], but they are still in the preliminary research stage, research on treatment methods for NSSI is still limited, and the effectiveness of treatment still needs to be explored [11, 12].”
Chung, H.-U., Kim, G., Kim, D.-I., & Hur, J. (2025) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2025.152610 · Cited by 6
Julià, A., Jaén, I., García‐Palacios, A., Pascual, J. C., Sintes, A., Lara, A., Méndez, I., Romero, S., Puntí, J., Soler, J., et al. (2025) · Internet Interventions · doi:10.1016/j.invent.2025.100826 · Cited by 5
“Therefore, a large proportion of people engaging in SITB lack access to evidence-based interventions (Hawton et al., 2015, 2016; Hetrick et al., 2016; Jobes, 2012; Mehlum et al., 2019; Turner et al., 2014).”
Emotion regulation in self-injurious youth: A tale of two circuits.
Santana-Gonzalez, C., Ranatunga, J., Nguyen, G. H., Greiskalns, B., Das, N., Lattimer, E., Maurice, M., Yi, G., Zietlow, A.-L., Eckstein, M., et al. (2024) · Psychiatry research. Neuroimaging · doi:10.1016/j.pscychresns.2024.111944 · Cited by 6
Zhou, L., Ye, Y., Liu, B., Zhou, L., Sheng, J., Zhang, X.-F., Deng, X., & Ran, M. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1446727 · Cited by 9
“The etiology of NSSI is multifactorial, involving individual psychological traits, social environment, and family background (8).”
BackgroundDeng, Y., Ye, B., & Yang, Q. (2024) · Children and Youth Services Review · doi:10.1016/j.childyouth.2024.107543 · Cited by 5
Personality Disorder Symptoms in Intermittent Explosive Disorder: A Latent Class Analysis
Ciesinski, N. K., Drabick, D. A. G., Berman, M. E., & McCloskey, M. S. (2024) · Journal of Personality Disorders · doi:10.1521/pedi.2024.38.1.34 · Cited by 6
Geng, S., Wang, L., Sun, J.-P., Xu, M., Zhang, L., Yi, Z., Ji, J., & Zhang, X. (2023) · Clinical Child Psychology and Psychiatry · doi:10.1177/13591045231169087 · Cited by 6
“However, a paucity of well-controlled studies have examined the efficacy of treatment for NSSI (Turner et al., 2014).”
BackgroundGuo, J., Ying, J., Zhou, X., Wang, C., Lin, N., & You, J. (2022) · Current Psychology · doi:10.1007/s12144-022-03166-z · Cited by 7
Foynes, M. M., Singh, R. S., & Landes, S. J. (2021) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2021.10.005 · Cited by 5
Wichniak, A., Samochowiec, J., Szulc, A., Dudek, D., Heitzman, J., Janas-Kozik, M., Wolańczyk, T., Rymaszewska, J., Siwek, M., & Bieńkowski, P. (2021) · Psychiatria Polska · doi:10.12740/pp/138177 · Cited by 6
“There are also literature reports on the efficacy of aripiprazole in self-harm, that may be associated with personality disorders [88].”
Pain perception and nonsuicidal self-injurious behavior
Зинчук, М. С., Аведисова, А. С., Voinova, N., Kustov, G., Pashnin, E., Gulyaeva, N. V., & Guekht, A. B. (2020) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro2020120121144 · Cited by 7
Personality Traits, Early Maladaptive Schemas, and Severity of Nonsuicidal Self-Injury
Arthurs, S., & Tan, J. C. H. (2017) · doi:10.24839/2325-7342.jn22.3.181 · Cited by 6
Impulsive-addictive-compulsive Types of Non-suicidal Self-injury: A Case Series
Elango, S. C., Sharma, E., & Roopesh, B. N. (2025) · Indian Journal of Psychological Medicine · doi:10.1177/02537176241300760 · Cited by 4
Hudson, E., Hartley, S., & Taylor, P. (2024) · Psychology and psychotherapy · doi:10.1111/papt.12567 · Cited by 5
“Within the literature and clinical interventions, NSSI recovery is frequently conceptualised as the reduction or cessation of self-injuring behaviours (Calati & Courtet, 2016; Grunberg & Lewis, 2015; Kress & Hoffman, 2008; Turner et al., 2014).”
Use of the opioid receptor antagonist – naltrexone in the treatment of non-suicidal self-injury
Karakuła‐Juchnowicz, H., Banaszek, A., & Juchnowicz, D. (2023) · Psychiatria Polska · doi:10.12740/pp/onlinefirst/161954 · Cited by 10
“The best-studied opioid antagonists are naloxone and naltrexone, both of which are used in the pharmacotherapy of NSSI [30, 31, 35, 36].”
InfluentialLindquist, E. G., & West, A. (2023) · Archives of Suicide Research · doi:10.1080/13811118.2023.2193594 · Cited by 5
“The lifetime risk of NSSI is 5%, with anywhere from 13.9 to 35.6% of adolescents and 20% of college students engaging in NSSI (Cipriano, Cella, & Cotrufo, 2017; Turner, Austin, & Chapman, 2014).”
BackgroundInfluentialTaylor, P. J., Duxbury, P. J., Moorhouse, J., Russell, C., Pratt, D., Parker, S., Sutton, C., Lobban, F. A., Drake, R., Eccles, S., et al. (2023) · Pilot and Feasibility Studies · doi:10.1186/s40814-023-01273-7 · Cited by 8
Fetal Alcohol Spectrum Disorder and Suicidality: What Does the Literature Tell Us?
Flannigan, K., Wrath, A. J., Badry, D., McMorris, C., Ewasiuk, A., Campbell, A., & Harding, K. D. (2022) · Journal of Mental Health Research in Intellectual Disabilities · doi:10.1080/19315864.2022.2082604 · Cited by 5
“…aspects of suicidality have unique implications for risk assessment, intervention responses, and trajectories (Batterham et al., 2015; Horváth et al., 2020; Turner et al., 2014), and therefore a more nuanced understanding of the spectrum of suicidality among individuals with FASD is needed.”
BackgroundLewis, S. P., Kenny, T. E., Pritchard, T. R., Labonte, L., Heath, N., & Whitley, R. (2022) · Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001541 · Cited by 5
“Although many of the strategies reported by participants in this study were evidence-informed (e.g., distraction, social support; Glenn et al., 2019; Turner et al., 2014), others were not (e.g., replacement behaviors, substance use) and may do more harm than good (Wadman et al., 2020).”
BackgroundPrevalence and Correlates of Self-Injurious Behaviors Among Justice-Involved Youth
Jin, H., Marshall, B., Kemp, K., & Tolou-Shams, M. (2021) · Journal of correctional health care · doi:10.1089/jchc.19.04.0027 · Cited by 5
“…justice systems is the key to promote enhanced screening efforts of SIB with FTO-CINI youth and cross-training in available local interventions to improve access to evidenced-based treatment, such as structured psychotherapeutic approaches and pharmacological interventions (Turner et al. , 2014).”
Schmelefske, E., Per, M., Anand, L., Khoury, B., & Heath, N. L. (2025) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-025-04962-3 · Cited by 2
“13, 14 Embodied and Embedded Mindfulness and Self-Compassion Dispositional mindfulness is de�ned by most Western researchers as the practice of deliberately attending to experiences in the present moment, with an attitude of non-judgement, openness, and acceptance.”
Jansen, M., & L'ecuyer, S. (2021) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001381 · Cited by 4
Saxena, O., Kishore, M. T., Kumar, A., Sagar, K. J. V., & Binukumar, B. (2023) · Journal of Indian Association for Child and Adolescent Mental Health · doi:10.1177/09731342231196370 · Cited by 3
Deering, K., & Williams, J. (2017) · International Journal of Mental Health Nursing · doi:10.1111/inm.12387 · Cited by 17
“In order to yield more results, every search employed a singular term for self-harm from the reviews of Ward et al. (2013) and Turner et al. (2014), combined with a term from CHIME in all of the designated databases.”
MethodBaek, J., Lee, J., Park, W., & Kim, D. (2026) · Cognitive Therapy and Research · doi:10.1007/s10608-026-10726-1 · Cited by 2
“Such stratification can optimize service capacity without reducing clinical effectiveness (Turner et al., 2014).”
Neural circuit for Non-Suicidal Self-Injury and Causal Clinical Validation.
Wang, S., Wu, Y., Wang, W.-J., Zhang, J.-H., Geng, F., Li, Q.-Q., Xiao, G., Zu, M.-D., Nie, J., Ni, L.-P., et al. (2025) · Behavioural Brain Research · doi:10.1016/j.bbr.2025.115736 · Cited by 3
Thai, M., Başgöze, Z., Schreiner, M. W., Roediger, D. J., Falke, C. A., Mueller, B. A., Fiecas, M. J. A., Quevedo, K. M., Pfeifer, J. H., Klimes‐Dougan, B., et al. (2024) · Psychological Medicine · doi:10.1017/s0033291724001399 · Cited by 5
Langjord, T., Pedersen, G., Bovim, T., Bremer, K., Christensen, T. B., Hove, O., Kildahl, A. N., Mork, E., Norheim, A. B., Ramleth, R., et al. (2024) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2024.2376162 · Cited by 3
“Current evidence on SH treatment is represented in a large body of research, mainly based on the milder, and more common conditions; self-harming behaviors with no intent of suicide (non-suicidal self-injury [15–17].”
Hach, I., Bertsch, T., & Nonell, P. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1240681 · Cited by 3
“Reducing NSSIs and/or reducing symptoms of borderline personality disorders (clinical prevalence of borderline personality disorders is 11% in adolescents and up to 76% in emergency departments) might have been a therapeutic impact of aripiprazole and quetiapine prescribed by physicians (40).”
BackgroundInfluentialThe Relationship Between Self-Harm and Suicide in Adolescents and Young Adults
Brañas, M. J. A. A., Croci, M. S., Murray, G. E., & Choi-Kain, L. (2022) · Psychiatric annals · doi:10.3928/00485713-20220715-01 · Cited by 3
Pharmacological interventions for self-harm in adults
Witt, K., Hetrick, S. E., Rajaram, G., Hazell, P., Salisbury, T. T., Townsend, E., & Hawton, K. E. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013669.pub2 · Cited by 22
Intentional foreign body ingestion: What do we know and how can we help?
Kienzle, A., & Warner, V. (2016) · Nursing · doi:10.1097/01.nurse.0000481436.25049.22 · Cited by 3
Lint, A. H., Walsh, R. F. L., Sheehan, A. E., Cheek, S. M., & Liu, R. T. (2026) · Journal of Mood and Anxiety Disorders · doi:10.1016/j.xjmad.2026.100190 · Cited by 2
“That is, there may be significant heterogeneity within SA and NSSI, respectively, corresponding to variance in underlying risk profiles, that is missed in treating each as a homogenous outcome [8 – 11].”
Kang, T.-J., Zhao, X., Huo, X.-N., Liu, X., Wang, Y.-N., Wang, X.-L., Ding, X.-B., & Wu, H. (2026) · JAMA Network Open · doi:10.1001/jamanetworkopen.2026.17336 · Cited by 2
Zhang, C., Qu, D., Chong, D., Lei, C., Shen, Y., Cui, X., He, Y., Li, Y., Ou, J., & Chen, R. (2025) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.70054 · Cited by 3
Chen, Y., Yang, X., Liao, K., Yu, R., Chen, X., Zhang, W., & Liu, N. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07106-6 · Cited by 2
“Previous studies suggested that the use of antidepressant medication was an effective treatment for NSSI in adolescents, which may contribute to an decreased risk of suicidal behavior in youths [7, 8].”
Supporting Clients Who Self-Injure: A Person-Centered Approach
Lewis, S. P., Hasking, P., & Boyne, H. P. (2025) · Journal of Health Service Psychology · doi:10.1007/s42843-025-00131-9 · Cited by 2
“Here, DBT strategies such as distress tolerance and coping with emotional pain have been recommended (Hasking et al., 2023; Turner et al., 2014).”
Kim, S., & Lee, D. (2025) · PLoS ONE · doi:10.1371/journal.pone.0316619 · Cited by 2
Echoes of Pain: Navigating Non-suicidal Self-injury in Schizophrenia—Clinical Chronicles
Biswal, J., Agarwal, K., Deepanshu, M., & Sahoo, S. (2024) · Indian Journal of Psychological Medicine · doi:10.1177/02537176241292799 · Cited by 3
“21”
Rodante, D., Chiapella, L. C., Fedi, R. O., Papávero, E. B., Lavoie, K., & Daray, F. M. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1087097 · Cited by 5
Effects of Group Psychotherapy for Nonsuicidal Self-Injury: A Meta-Analysis
Masland, S. R., Finch, E. F., & Schnell, S. E. (2023) · International Journal of Group Psychotherapy · doi:10.1080/00207284.2023.2191683 · Cited by 2
“…with brief intervention, developmentally oriented interventions for adolescents, emotion regulation group therapy, cognitive therapy, dynamic deconstructive therapy, integrated family therapy, and pharmacological interventions (see Flaherty, 2018; Glenn et al., 2019; Turner et al., 2014).”
BackgroundImplicit cognitions on self-injurious and suicidal behavior in borderline personality disorder
Scheunemann, J., Kühn, S., Biedermann, S. V., Lipp, M., Peth, J., Gallinat, J., & Jelinek, L. (2023) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2023.101836 · Cited by 2
Prevalence and Correlates of Self-Injury among Adolescents: A Cross-Sectional Study
Domingues, P. N., & da Silva, T. F. (2022) · International Journal of Clinical Psychiatry and Mental Health · doi:10.12970/2310-8231.2022.10.02 · Cited by 2
“Different methods can be used in association [10-12].”
BackgroundMethodInfluentialNonsuicidal Self-Injury: A Nurse-Led Quality Improvement Project to Address Self-Harm.
Goodman, D., Pletch, A., Paul, P., Anderson, E., & Kverno, K. S. (2022) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/02793695-20220208-02 · Cited by 2
Kerkelä, M., Gissler, M., & Veijola, J. M. (2022) · Epidemiology and Health · doi:10.4178/epih.e2022005 · Cited by 2
Group-based intervention for eating disorders with non-suicidal-self-injury: a case series
Vieira, A., Rodrigues, T. F., Brandão, I., Timóteo, S., Nunes, P., & Gonçalves, S. (2021) · Clinical Psychologist · doi:10.1080/13284207.2021.1892454 · Cited by 2
Несуицидальные самоповреждения подростков: общее и особенное. Часть II
Любов, Е. Б., & Zotov, P. B. (2020) · Суицидология · doi:10.32878/suiciderus.20-11-04(41)-26-55 · Cited by 2
Rationalizing self-defeating behaviors: Theory and evidence
Lefgren, L. J., Stoddard, O. B., & Stovall, J. E. (2020) · Journal of Health Economics · doi:10.1016/j.jhealeco.2020.102407 · Cited by 4
“Following Jacob and Lefgren (2003), one could observe whether NSSI was less common during teacher in-service days when school was out of session to otherwise similar days when school was in session.”
BackgroundInfluentialTreatment of nonsuicidal self-injury disorder with oral ketamine
Vanle, B., Fuller, M. C., Hangiandreou, G., & Silverman, S. (2019) · Heart and Mind · doi:10.4103/hm.hm_50_19 · Cited by 2
“Although selective serotonin reuptake inhibitors are widely used, it remains unclear whether they are useful in nondepressed NSSID patients.[3] Given the dearth of evidence regarding effective treatment of this highly impairing condition, we describe the first case of NSSI who achieved remission with oral ketamine.”
BackgroundPsychopharmacotherapy of Severe Self-Injury in an Adolescent with Gender Dysphoria and Comorbidity
Rice, T., Kufert, Y., Walther, A., Feldman, E., García-Delgar, B., & Coffey, B. J. (2016) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2016.29114.bjc · Cited by 1
“Guidelines on NSSI suggest—but cannot clearly demonstrate— that psychopharmacological intervention for NSSI is effective in the child and adolescent (Hawton et al. 2015) and young adult populations (Turner et al. 2014).”
Alniak, I., & Güney, E. (2021) · Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi · doi:10.14744/dajpns.2021.00142 · Cited by 2
“340 +Length of last hospitalization (days) (n=85) 15 (5-75) 15 (7-35) -0.”
BackgroundInfluentialSun, S., Hong, L., Tong, S., Zheng, M., Sun, J., Yan, S., Zhao, K., Shi, W., & He, H. (2026) · BMC Psychology · doi:10.1186/s40359-026-04479-5 · Cited by 1
“For middle adolescence, integrating evidence-based psycho-therapies that target these internalizing processes into treatment plans is recommended, such as Dialectical Behavior Therapy (DBT) [11, 57].”
Non-Suicidal Self-Injury in Adolescence and Youth
Петрова, Н. Н. (2025) · Psikhiatriya · doi:10.30629/2618-6667-2025-23-4-103-116 · Cited by 1
Unterschemmann, S., Mueller, E. M., Lux, S., Philipsen, A., & Schulze, M. (2025) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-025-00304-4
“Even though therapy seems to be partially successful [22, 75, 76, 102], complete remission remains rare with some studies reporting a total absence after therapy in only 25% [85].”
Exploring Voluntary Disclosure of Non‐Suicidal Self‐Injury: A Thematic Analysis
Mirichlis, S., Lewis, S. P., Boyes, M., & Hasking, P. (2025) · Journal of Community & Applied Social Psychology · doi:10.1002/casp.70126 · Cited by 1
Calvo, N., Amoretti, S., Lugo-Marín, J., Oriol, M., Perez, C., Ramos-Quiroga, J., & Ferrer, M. (2025) · European Journal of Psychiatry · doi:10.1016/j.ejpsy.2024.100288 · Cited by 1
“17 The latest studies indicate that this stage coincides with what some authors have begun to call the Transitional Age Youth (TAY), a period of transition that begins around ages 15 - 16 and persists beyond 25 years, thus including the two classic groups of “ adolescence ” or “ young adults, ”…”
InfluentialYin, Y.-Q., Zhang, S.-F., Yu, L., Shi, F., & Yu, G.-L. (2025) · Journal of Psychiatric Practice · doi:10.1097/pra.0000000000000846 · Cited by 1
“15 Past studies indicate that NSSI has been treated using dialectical behavior therapy for adolescents, 16 – 18 mentalization-based treatment for adolescents, 19,20 and cognitive-behavioral therapy.”
Abursu, H., Hesapçıoğlu, S. T., & Ceylan, M. F. (2024) · Qatar medical journal · doi:10.5339/qmj.2024.69 · Cited by 1
Wollweber, B., Keck, M., & Schmidt, U. (2015) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125315585652 · Cited by 1
“To the best of the authors’ knowledge, there is so far only one randomized controlled trial (RCT) that assessed the efficacy of medication for reduction of NSSI [Turner et al. 2014].”
BackgroundNyakundi, J. K., & Wairungu, G. (2021) · International journal of research and innovation in social science · doi:10.47772/ijriss.2021.5725 · Cited by 1
“Finally, medications targeting the serotonergic, dopaminergic and opioid systems also have demonstrated some benefits as well (Turner et al., 2014).”
BackgroundVictor, S. E. (2016) · doi:10.14288/1.0308725 · Cited by 1
Longitudinal changes in endocannabinoids and clinical course of adolescent non-suicidal self-injury
Ferger, M. D., Brodesser, S., Kaess, M., & Koenig, J. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-04391-x
“Psychotherapy (i.e., dialectical behavior therapy for adolescents (DBT-A) and cognitive behavioral therapy (CBT)), aiming at reducing dysfunctional and promoting functional coping strategies, are effective in the treatment of adolescent NSSI [12 – 14].”
Euthanasia of a macaque with self-injurious behavior in a visual neuroscience laboratory
Horton, J. C. (2026) · Animal advances · doi:10.48130/animadv-0026-0018
“These classes of medications have also been used to treat non-suicidal self-injury in humans, but data showing efficacy are weak [37] .”
Efektivitas Dukungan Teman Sebaya dan Art Therapy terhadap NSSI SMK Citra Medika Gender
Sumarni, D. W., Kusumadewi, A. F., Erlina, E., Khairani, N. R., Missi, E. T. E., Purwanta, P., & Winarni, R. A. (2026) · Jurnal Wanita dan Keluarga · doi:10.22146/jwk.27677
“Secara teoritis, konseling suportif dapat membantu remaja dalam memproses stres, meningkatkan self-acceptance , dan merekonstruksi pola pikir negatif (Turner et al ., 2022).”
Alberdi‐Páramo, Í., Rodrigo-Holgado, I., & Díaz‐Marsá, M. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1843176
“When feasible, elements of evidence-based psychotherapeutic approaches can be incorporated into acute care (78).”
InfluentialBi, J., Liu, P., Xue, Z., Li, X., Xu, Q., Jia, Y., & Lu, J. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1871678 · Cited by 1
“However, the treatment effects of existing NSSI interventions are generally moderate, highlighting the need for further identi fi cation of potentially malleable intervention targets (9, 10).”
Giménez, M. C., Jaén, I., Vega, D., Julià, A., López-Solá, M., Solé-Casals, J., Miralles, I., & García-Palacios, A. (2026) · Frontiers in Digital Health · doi:10.3389/fdgth.2026.1794576
Park, K. J., Kim, Y. W., Jung, E., Kim, J. Y., & Kim, H. (2026) · Bipolar Disorders · doi:10.1111/bdi.70125
“As AAPs are commonly prescribed to manage self-harm behaviors [30], this discrepancy in clinical characteristics may partially explain the higher rate of AAP prescriptions among girls.”
Ji, Y., Chen, X., Zheng, Q., Liu, Q., Zhang, C., Zhang, T.-T., & Li, L.-J. (2026) · World Journal of Psychiatry · doi:10.5498/wjp.v16.i3.113825
Du, L., Zong, X., He, J., Feng, M., Li, H., Tan, Y., Dong, L., Sun, X., Zhang, Y., Yin, S., et al. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1748315
Cook, V., & Mason, J. (2026) · Clinical Case Studies · doi:10.1177/15346501261425244
“Despite DBT demonstrating reductions in BPD symptoms, several randomised controlled trials suggest that it has mixed or modest effects on reducing self-injury speci fi cally (Turner et al., 2014).”
Therapeutic Nursing Interventions to Reduce Self-Injurious Behavior: A Scoping Review
Putri, T. H., Suryani, S., Abdullah, K. L., Andriyani, S., Fujiana, F., & Syisnawati, S. (2025) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s553691
“21 However, the results of this review demonstrate that nurses can lead a therapeutic role in reducing SIB in various clinical and non-clinical healthcare settings.”
Chmelíková, M. (2025) · Psychiatrie pro praxi · doi:10.36290/psy.2025.026
A Case of Repeated Cardiac Trauma Caused by Sewing Needles
Oshiro, N., Yoshida, T., Higuchi, T., & Kawashima, T. (2025) · Japanese Journal of Cardiovascular Surgery · doi:10.4326/jjcvs.54.233
A way of survival: A Qualitative Study of Non suicidal Self Injury Behavior in Adolescents
Su, C.-Y., Ji, Y.-T., & Liu, W. (2025) · The Journal of Medicine, Humanity and Media · doi:10.62787/mhm.v3i2.132
Non-suicidal self-harm and its addictive potential in adolescents with drug-related disorders
Muradian, A., Timerbulatova, M., & Timerbulatov, I. F. (2025) · Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery) · doi:10.33920/med-01-2504-02
Ghaedi-Heidari, F., Maghsoudi, J., Bahrami, M., Kheirabadi, G., Noori‐Rahmatabadi, B., Hermis, A. H., Jaasim, K. H., Ajel, M. A., & Zakeri, M. (2025) · Nursing Open · doi:10.1002/nop2.70188
“People with experience of self-harm are more probable to visit the emergency department and psychiatric centres more than once a year (Turner et al. 2014).”
Subgroups of non-suicidal self-injury in a large diverse sample of online help-seekers
Kruzan, K., Washburn, J. J., Aaby, D., Nguyen, T., & Mohr, D. C. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1513685
Calvo, N., Lugo-Marin, J., García-Martínez, Á., Alonzo-Castillo, T., Ferrer, S., Oriol-Escudé, M., Pérez-Galbarro, C., Ramos-Quiroga, J., & Ferrer, M. (2024) · Revista de Psiquiatría Infanto-Juvenil · doi:10.31766/revpsij.v41n4a4
Shi, X.-L., Hou, M., Chen, X., & Zhu, Y. (2024) · Nature and Science of Sleep · doi:10.2147/nss.s470557
“67,68 In addition, self-compassion-oriented prevention and intervention programs, such as compassion-focused therapy (CFT) and mindful self-compassion (MSC), may hold great promise in reducing the incidence of NSSI.”
Background
Metadata
- Authors
- Turner, B. J., Austin, S. B., & Chapman, A. L.
- Affiliations
- Simon Fraser University (CA)
- Corresponding author
- Turner, Brianna J
- Venue
- The Canadian Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2014-11
- Volume
- 59
- Issue
- 11
- Pages
- 576-585
- ISSN
- 0706-7437 (ISSN-L)
- 1497-0015
- PMC
- PMC4244876
- OpenAlex
- W2226199416
- Cited by
- 259
- References
- 109
- Citations by year
- 2026: 17 · 2025: 30 · 2024: 31 · 2023: 36 · 2022: 23 · 2021: 37 · 2020: 19 · 2019: 13 · 2018: 15 · 2017: 15 · 2016: 17 · 2015: 3 · 2014: 1
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Canadian Journal of Psychiatry (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Psychological Association
- Michael Smith Health Research BC
- Health Canada
- Canadian Institutes of Health Research
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- non-suicidal self-injury, suicidal self-injury, psychological intervention, pharmacotherapy, dialectical behavior therapy, atypical antipsychotics, aripiprazole, naltrexone, selective serotonin reuptake inhibitors, cognitive behavioral therapy, treatment efficacy
- MeSH terms
- Adolescent, Adult, Borderline Personality Disorder, Combined Modality Therapy, Humans, Psychotherapy, Psychotherapy, Group, Psychotropic Drugs, Suicide, Attempted, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Self-Injurious Behavior, Outcome Assessment, Health Care, Young Adult, Theory of Mind
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review