Pharmacotherapy of Eating Disorders
Abstract
Eating disorders are complex, chronic disorders that are difficult to treat. In addition, the 2 primary eating disorders, anorexia nervosa and bulimia nervosa, may have acute, life‐threatening consequences. Medication trials for eating disorders have been hampered by high dropout rates, high placebo response, short trial duration, insufficient doses, and difficult outcome measures. Only 1 medication has been FDA approved for any eating disorder to date, and that is for fluoxetine in the treatment of bulimia. Clearly, new large‐scale, independent studies using novel agents, and studying the use of medications for both short‐ and long‐term outcomes, are needed.
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Of the numerous trials of psychopharmacologic agents for the treatment of BN, none has been primarily a DA agent.
“Of the numerous trials of the effects of psychopharmacologic agents for the treatment of BN, none has been primarily a DA agent [333].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [333]
Psychopharmacologic treatments for anorexia nervosa have yielded only moderate success, and the majority are antidepressants that act primarily on non-DA systems.
“Psychopharmacologic treatments for AN have yielded only moderate success, and the majority of treatments are antidepressants that act primarily on non-DA systems [333].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [333]
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- Authors
- Jackson, C. W., Cates, M., & Lorenz, R.
- Affiliations
- University of Alabama at Birmingham (US)
- University of South Alabama (US)
- Corresponding author
- Jackson, Cherry Wyant
- Venue
- Nutrition in Clinical Practice
- Publisher
- Wiley
- Published
- 2010-04
- Volume
- 25
- Issue
- 2
- Pages
- 143-159
- ISSN
- 0884-5336 (ISSN-L)
- 1941-2452
- OpenAlex
- W2083716511
- Cited by
- 28
- References
- 74
- Citations by year
- 2026: 2 · 2023: 1 · 2021: 1 · 2020: 1 · 2017: 1 · 2016: 1 · 2015: 5 · 2014: 4 · 2013: 3 · 2012: 7
- FWCI
- 0.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nutrition in Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Medicine › Pharmacology › Pharmacology and Obesity Treatment
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Keywords
- eating disorders, pharmacotherapy, anorexia nervosa, bulimia nervosa, fluoxetine, antidepressants, drug trials, trial dropout, placebo response, FDA-approved drugs, long-term outcomes
- MeSH terms
- Anorexia Nervosa, Antidepressive Agents, Combined Modality Therapy, Humans, Prognosis, Treatment Outcome, Nutrition Therapy, Bulimia Nervosa
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