The glucocorticoid receptor: part of the solution or part of the problem?

Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic parameters and body composition

van Rossum, E. F. C. (2004) · Recent Progress in Hormone Research · doi:10.1210/rp.59.1.333 · Cited by 381 · see citing works

Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior

Boyle, M. P., Brewer, J. A., Funatsu, M., Wozniak, D. F., Tsien, J. Z., Izumi, Y., & Muglia, L. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406458102 · Cited by 378 · see citing works

Mineralocorticoid Receptor Function in Major Depression

Young, E. A., Lopez, J. F., Murphy-Weinberg, V., Watson, S. J., & Akil, H. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.1.24 · Cited by 204 · see citing works

Effects of Cytokines on Glucocorticoid Receptor Expression And Function: Glucocorticoid Resistance and Relevance to Depression

Miller, A. H., Pariante, C. M., & Pearce, B. D. (1999) · Advances in Experimental Medicine and Biology · doi:10.1007/978-0-585-37970-8_7 · Cited by 203 · see citing works

Steroid-Independent Translocation of the Glucocorticoid Receptor by the Antidepressant Desipramine

Pariante, C. M., Pearce, B. D., Pisell, T. L., Owens, M. J., & Miller, A. H. (1997) · Molecular Pharmacology · doi:10.1124/mol.52.4.571 · Cited by 156 · see citing works

Increased Pituitary Volume in Antipsychotic-Free and Antipsychotic-Treated Patients of the Æsop First-Onset Psychosis Study

Pariante, C. M., Dazzan, P., Danese, A., Morgan, K. D., Brudaglio, F., Morgan, C., Fearon, P., Orr, K., Hutchinson, G., Pantelis, C., et al. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300766 · Cited by 152 · see citing works

Glucocorticoid Receptor Function<i>In Vitro</i>in Patients with Major Depression

Pariante, C. M. (2004) · Stress · doi:10.1080/10253890500069650 · Cited by 147 · see citing works

Interleukin 1α (IL-1α) induced activation of p38 mitogen-activated protein kinase inhibits glucocorticoid receptor function

Wang, X., Wu, H., & Miller, A. H. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001339 · Cited by 128 · see citing works

The Antidepressant Clomipramine Regulates Cortisol Intracellular Concentrations and Glucocorticoid Receptor Expression in Fibroblasts and Rat Primary Neurones

Pariante, C. M., Hye, A., Williamson, R., Makoff, A., Lovestone, S., & Kerwin, R. W. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300195 · Cited by 70 · see citing works

Psychopathological symptoms during interferon-α and ribavirin treatment: effects on virologic response

Maddock, C., Landau, S., Barry, K., Maulayah, P., Hotopf, M., Cleare, A. J., Norris, S., & Pariante, C. M. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001634 · Cited by 54 · see citing works

The Proinflammatory Cytokine, Interleukin-1α, Reduces Glucocorticoid Receptor Translocation and Function¹

Pariante, C. M., Pearce, B. D., Pisell, T. L., Sanchez, C. I., Po, C., Su, C., & Miller, A. H. (1999) · Endocrinology · doi:10.1210/en.140.9.4359 · Cited by 40 · see citing works

The HPA axis in major depression: classical theories and new developments

Pariante, C. M., & Lightman, S. L. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.06.006 · Cited by 2,009 · see citing works

Neuroimmune mechanisms of depression

Hodes, G. E., Kana, V., Menard, C., Merad, M., & Russo, S. J. (2015) · Nature Neuroscience · doi:10.1038/nn.4113 · Cited by 585 · see citing works

Glucocorticoids, cytokines and brain abnormalities in depression

Zunszain, P. A., Anacker, C., Cattaneo, A., Carvalho, L. A., & Pariante, C. M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.04.011 · Cited by 554 · see citing works

Gut Microbiota, Bacterial Translocation, and Interactions with Diet: Pathophysiological Links between Major Depressive Disorder and Non-Communicable Medical Comorbidities

Slyepchenko, A., Maes, M., Jacka, F. N., Köhler, C. A., Barichello, T., McIntyre, R. S., Berk, M., Grande, I., Foster, J. A., Vieta, E., et al. (2017) · Psychotherapy and Psychosomatics · doi:10.1159/000448957 · Cited by 278 · see citing works

Aging and the HPA axis: Stress and resilience in older adults

Gaffey, A. E., Bergeman, C. S., Clark, L. A., & Wirth, M. M. (2016) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.036 · Cited by 273 · see citing works

Early life adversity and the epigenetic programming of hypothalamic-pituitary-adrenal function

Anacker, C., O'Donnell, K. J., & Meaney, M. J. (2014) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2014.16.3/canacker · Cited by 237 · see citing works

Glucocorticoid Receptor and FKBP5 Expression Is Altered Following Exposure to Chronic Stress: Modulation by Antidepressant Treatment

Guidotti, G., Calabrese, F., Anacker, C., Racagni, G., Pariante, C. M., & Riva, M. A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2012.225 · Cited by 200 · see citing works

Not fade away: the HPA axis and depression

Cowen, P. J. (2010) · Psychological Medicine · doi:10.1017/s0033291709005558 · Cited by 191 · see citing works

Minocycline ameliorates depressive behaviors and neuro-immune dysfunction induced by chronic unpredictable mild stress in the rat

Zhang, C., Zhang, Y.-P., Li, Y.-Y., Liu, B.-P., Wang, H.-Y., Li, K.-W., Zhao, S., & Song, C. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.07.001 · Cited by 172 · see citing works

Different responses to dexamethasone and prednisolone in the same depressed patients

Juruena, M. F., Cleare, A. J., Papadopoulos, A. S., Poon, L., Lightman, S., & Pariante, C. M. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0555-4 · Cited by 147 · see citing works

Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression

Nikkheslat, N., Zunszain, P. A., Horowitz, M. A., Barbosa, I. G., Parker, J. A., Myint, A.-M., Schwarz, M. J., Tylee, A. T., Carvalho, L. A., & Pariante, C. M. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.02.002 · Cited by 147 · see citing works

Inflammatory biomarker profiles of mental disorders and their relation to clinical, social and lifestyle factors

Baumeister, D., Russell, A., Pariante, C. M., & Mondelli, V. (2014) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-014-0887-z · Cited by 142 · see citing works

Neuroactive Steroids and GABAergic Involvement in the Neuroendocrine Dysfunction Associated With Major Depressive Disorder and Postpartum Depression

Maguire, J. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00083 · Cited by 113 · see citing works

The impact of treatment on HPA axis activity in unipolar major depression

McKay, M. S., & Zakzanis, K. K. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.07.012 · Cited by 103 · see citing works

The interface of stress and the HPA axis in behavioural phenotypes of mental illness

Baumeister, D., Lightman, S. L., & Pariante, C. M. (2014) · Current topics in behavioral neurosciences · doi:10.1007/7854_2014_304 · Cited by 104 · see citing works

Clomipramine in vitro reduces glucocorticoid receptor function in healthy subjects but not in patients with major depression

Carvalho, L. A., Juruena, M. F., Papadopoulos, A. S., Poon, L., Kerwin, R., Cleare, A. J., & Pariante, C. M. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.44 · Cited by 75 · see citing works

Pituitary volume in psychosis: the first review of the evidence

Pariante, C. M. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107084020 · Cited by 73 · see citing works

Mechanisms of brain glucocorticoid resistance in stress-induced psychopathologies

Merkulov, V. M., Merkulova, T. I., & Bondar, N. P. (2017) · Biochemistry (Moscow) · doi:10.1134/s0006297917030142 · Cited by 65 · see citing works

Early life trauma, depression and the glucocorticoid receptor gene—An epigenetic perspective

Smart, C., Strathdee, G., Watson, S., Murgatroyd, C., & McAllister-Williams, R. H. (2015) · Psychological Medicine · doi:10.1017/s0033291715001555 · Cited by 61 · see citing works

Circadian activity of the hypothalamic-pituitary-adrenal axis is differentially affected in the rat chronic mild stress model of depression

Christiansen, S., Bouzinova, E. V., Palme, R., & Wiborg, O. (2012) · Stress · doi:10.3109/10253890.2011.654370 · Cited by 55 · see citing works

The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice

Yau, J. L. W., Noble, J., Thomas, S., Kerwin, R., Morgan, P. E., Lightman, S., Seckl, J. R., & Pariante, C. M. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301389 · Cited by 46 · see citing works

Pituitary volume, stress reactivity and genetic risk for psychotic disorder

Habets, P., Collip, D., Myin-Germeys, I., Gronenschild, E., van Bronswijk, S., Hofman, P., Lataster, T., Lardinois, M., Nicolson, N. A., van Os, J., et al. (2012) · Psychological Medicine · doi:10.1017/s0033291711002728 · Cited by 46 · see citing works

The effect of storage conditions on salivary cortisol concentrations using an Enzyme Immunoassay

Nalla, A. A., Thomsen, G., Knudsen, G. M., & Frokjaer, V. G. (2015) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365513.2014.985252 · Cited by 44 · see citing works

Central glucocorticoid receptor-mediated effects of the antidepressant, citalopram, in humans: a study using EEG and cognitive testing

Pariante, C. M., Alhaj, H. A., Arulnathan, V. E., Gallagher, P., Hanson, A., Massey, E., & McAllister-Williams, R. H. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.08.011 · Cited by 33 · see citing works

Are the thyroid and adrenal system alterations linked in depression?

Mokrani, M.-C., Duval, F., Erb, A., Gonzalez Lopera, F., & Danila, V. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.104831 · Cited by 28 · see citing works

Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated northern Swedish population

Ceulemans, S., De Zutter, S., Heyrman, L., Norrback, K., Nordin, A., Nilsson, L., Adolfsson, R., Del‐Favero, J., & Claes, S. (2011) · Bipolar Disorders · doi:10.1111/j.1399-5618.2011.00960.x · Cited by 22 · see citing works

Functional role of Calcium-stimulated adenylyl cyclase 8 in adaptations to psychological stressors in the mouse: implications for mood disorders

Razzoli, M., Andreoli, M., Maraia, G., Di Francesco, C., & Arban, R. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.07.022 · Cited by 20 · see citing works