The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Bioengineered Teeth from Cultured Rat Tooth Bud Cells
Open accessAbstract
The recent bioengineering of complex tooth structures from pig tooth bud tissues suggests the potential for the regeneration of mammalian dental tissues. We have improved tooth bioengineering methods by comparing the utility of cultured rat tooth bud cells obtained from three- to seven-day post-natal (dpn) rats for tooth-tissue-engineering applications. Cell-seeded biodegradable scaffolds were grown in the omenta of adult rat hosts for 12 wks, then harvested. Analyses of 12-week implant tissues demonstrated that dissociated 4-dpn rat tooth bud cells seeded for 1 hr onto PGA or PLGA scaffolds generated bioengineered tooth tissues most reliably. We conclude that tooth-tissue-engineering methods can be used to generate both pig and rat tooth tissues. Furthermore, our ability to bioengineer tooth structures from cultured tooth bud cells suggests that dental epithelial and mesenchymal stem cells can be maintained in vitro for at least 6 days.
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“The incidence of children born with missing primary and/or adult teeth issignificant (Nunn et al., 2003), and tooth loss in aged populations is also a prevalent health problem.”
Background
Cited by
Huang, G. T.-J., Gronthos, S., & Shi, S. (2009) · Journal of Dental Research · doi:10.1177/0022034509340867 · Cited by 1,871
Demineralization–remineralization dynamics in teeth and bone
Abou Neel, E., Aljabo, A., Strange, A., Ibrahim, S., Coathup, M., Young, A., Bozec, L., & Mudera, V. (2016) · International Journal of Nanomedicine · doi:10.2147/ijn.s107624 · Cited by 697
Fully functional bioengineered tooth replacement as an organ replacement therapy
Ikeda, E., Morita, R., Nakao, K., Ishida, K., Nakamura, T., Takano-Yamamoto, T., Ogawa, M., Mizuno, M., Kasugai, S., & Tsuji, T. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902944106 · Cited by 447
Stem cell-based biological tooth repair and regeneration
Volponi, A. A., Pang, Y., & Sharpe, P. T. (2010) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.09.012 · Cited by 318
Biodegradable inflatable balloon for reducing radiation adverse effects in prostate cancer
Levy, Y., Paz, A., Yosef, R. B., Corn, B. W., Vaisman, B., Shuhat, S., & Domb, A. J. (2009) · Journal of Biomedical Materials Research Part B: Applied Biomaterials · doi:10.1002/jbm.b.31467 · Cited by 52
Metadata
- Authors
- Duailibi, M. T., Duailibi, S. E., Young, C. S., Bartlett, J. D., Vacanti, J. P., & Yelick, P. C.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2004-07
- Volume
- 83
- Issue
- 7
- Pages
- 523-528
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2091298489
- Cited by
- 416
- References
- 18
- FWCI
- 6.89
- Type
- journal article
- Language
- en
- Open access
- green
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- Duailibi, M. T., Duailibi, S. E., Young, C. S., Bartlett, J. D., Vacanti, J. P., & Yelick, P. C. (2004). Bioengineered Teeth from Cultured Rat Tooth Bud Cells. Journal of Dental Research. https://doi.org/10.1177/154405910408300703
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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