Lysine-fortified wheat flour improves the nutritional and immunological status of wheat-eating families in northern China

Synergism of nutrition, infection, and immunity: an overview

Scrimshaw, N. S., & SanGiovanni, J. P. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.2.464s · Cited by 946 · see citing works

Food Composition Table

Trichopoulou, A. (1987) · Springer eBooks · doi:10.1007/978-3-642-82989-5_10 · Cited by 411 · see citing works

Nutrition, Immunity, and Infection

Morse, C. G., & High, K. P. (2010) · Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases · doi:10.1016/b978-0-443-06839-3.00010-2 · Cited by 304 · see citing works

Nutrition, Immunity, and Infection

Chandra, R. K., & Newberne, P. M. (1977) · Springer eBooks · doi:10.1007/978-1-4684-0784-6 · Cited by 189 · see citing works

Nitrogen and Amino Acid Requirements: The Massachusetts Institute of Technology Amino Acid Requirement Pattern

Young, V. R., & Borgonha, S. (2000) · Journal of Nutrition · doi:10.1093/jn/130.7.1841s · Cited by 156 · see citing works

Amino Acid Fortification of Protein Foods

(1972) · Journal of Nutrition Education · doi:10.1016/s0022-3182(72)80121-3 · Cited by 145 · see citing works

Lysine fortification of wheat flour improves selected indices of the nutritional status of predominantly cereal-eating families in Pakistan

Hussain, T., Abbas, S., Khan, M. A., & Scrimshaw, N. S. (2004) · Food and Nutrition Bulletin · doi:10.1177/156482650402500202 · Cited by 81 · see citing works

Protein Requirements of Man: Comparative Nitrogen Balance Response within the Submaintenance-to-maintenance Range of Intakes of Wheat and Beef Proteins

Young, V. R., Fajardo, L. F., Murray, E. B., Rand, W. M., & Scrimshaw, N. S. (1975) · Journal of Nutrition · doi:10.1093/jn/105.5.534 · Cited by 79 · see citing works

Lysine Enrichment of Wheat Flour: Evaluation in Infants

Graham, G. G., Placko, R. P., Acevedo, G., Morales, E., & Cordano, A. (1969) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/22.11.1459 · Cited by 48 · see citing works

Supplementation of Cereal Proteins with Amino Acids

Bressani, R., Wilson, D., Béhar, M., Chung, M., & Scrimshaw, N. S. (1963) · Journal of Nutrition · doi:10.1093/jn/79.3.333 · Cited by 45 · see citing works

Lysine supplementation of wheat gluten at adequate and restricted energy intakes in young men

Scrimshaw, N. S., Taylor, Y. S. M., & Young, V. R. (1973) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/26.9.965 · Cited by 37 · see citing works

Nitrogen Balance Responses of Young Men to Lysine Supplementation of Bread

Rice, H. L., Shuman, A. C., Matthias, R. H., & Flodin, N. W. (1970) · Journal of Nutrition · doi:10.1093/jn/100.7.847 · Cited by 14 · see citing works

Maternal Nutrition and Birth Outcomes

Abu-Saad, K., & Fraser, D. (2010) · Epidemiologic Reviews · doi:10.1093/epirev/mxq001 · Cited by 672 · see citing works

The Skeletal Muscle Anabolic Response to Plant- versus Animal-Based Protein Consumption

van Vliet, S., Burd, N. A., & van Loon, L. J. (2015) · The Journal of Nutrition · doi:10.3945/jn.114.204305 · Cited by 651 · see citing works

The Role of the Anabolic Properties of Plant- versus Animal-Based Protein Sources in Supporting Muscle Mass Maintenance: A Critical Review

Berrazaga, I., Micard, V., Gueugneau, M., & Walrand, S. (2019) · Nutrients · doi:10.3390/nu11081825 · Cited by 477 · see citing works

A meta-analysis of community-based studies on quality protein maize

Gunaratna, N. S., Groote, H. D., Nestel, P., Pixley, K. V., & McCabe, G. P. (2009) · Food Policy · doi:10.1016/j.foodpol.2009.11.003 · Cited by 126 · see citing works

Protein, lysine and vitamin D: critical role in muscle and bone health

Aggarwal, R., & Bains, K. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1855101 · Cited by 100 · see citing works

Lysine fortification reduces anxiety and lessens stress in family members in economically weak communities in Northwest Syria

Smriga, M., Ghosh, S. A., Mouneimne, Y., Pellett, P. L., & Scrimshaw, N. S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402550101 · Cited by 83 · see citing works

The Importance of Dietary Protein in Human Health

Henley, E. C., TAYLOR, J. R. N., & Obukosia, S. D. (2010) · Advances in food and nutrition research · doi:10.1016/s1043-4526(10)60002-2 · Cited by 79 · see citing works

Associations among High-Quality Protein and Energy Intake, Serum Transthyretin, Serum Amino Acids and Linear Growth of Children in Ethiopia

Tessema, M., Gunaratna, N. S., Brouwer, I. D., Donato, K., Cohen, J. L., McConnell, M. A., Belachew, T., Belayneh, D., & Groote, H. D. (2018) · Nutrients · doi:10.3390/nu10111776 · Cited by 82 · see citing works

Quality Protein Maize: Progress and Prospects

Atlin, G. N., Palacios‐Rojas, N., Babu, R., Das, B., Twumasi‐Afriyie, S., Friesen, D. K., Groote, H. D., Vivek, B., & Pixley, K. V. (2010) · Plant breeding reviews · doi:10.1002/9780470880579.ch3 · Cited by 74 · see citing works

The effectiveness of quality protein maize in improving the nutritional status of young children in the Ethiopian Highlands

Akalu, G., Taffesse, S., Gunaratna, N. S., & De Groote, H. (2010) · Food and Nutrition Bulletin · doi:10.1177/156482651003100304 · Cited by 70 · see citing works

Plant protein for food: opportunities and bottlenecks

Chardigny, J., & Walrand, S. (2016) · OCL · doi:10.1051/ocl/2016019 · Cited by 68 · see citing works

The requirements of protein & amino acid during acute & chronic infections.

Kurpad, A. V. (2006) · PubMed · Cited by 62 · see citing works

Optimization of the Nutrient Content and Protein Quality of Cereal—Legume Blends for Use as Complementary Foods in Ghana

Suri, D. J., Tano‐Debrah, K., & Ghosh, S. A. (2014) · Food and Nutrition Bulletin · doi:10.1177/156482651403500309 · Cited by 61 · see citing works

Lysine Fortification: Past, Present, and Future

Pellett, P. L., & Ghosh, S. A. (2004) · Food and Nutrition Bulletin · doi:10.1177/156482650402500201 · Cited by 57 · see citing works

Effect of lysine supplementation on health and morbidity in subjects belonging to poor peri-urban households in Accra, Ghana

Ghosh, S. A., Smriga, M., Vuvor, F., Suri, D. J., Mohammed, H., Armah, S. M., & Scrimshaw, N. S. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28834 · Cited by 51 · see citing works

L-lysine dietary supplementation for childhood and adolescent growth: Promises and precautions

Gunarathne, R., Guan, X., Feng, T., Zhao, Y., & Lu, J. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.05.014 · Cited by 52 · see citing works

Local Sources of Protein in Low- and Middle-Income Countries: How to Improve the Protein Quality?

Vissamsetti, N., Simon-Collins, M., Lin, S., Bandyopadhyay, S., Kuriyan, R., Sybesma, W., & Tomé, D. (2023) · Current Developments in Nutrition · doi:10.1016/j.cdnut.2023.102049 · Cited by 53 · see citing works

Lysine Requirements of Moderately Undernourished School-Aged Indian Children Are Reduced by Treatment for Intestinal Parasites as Measured by the Indicator Amino Acid Oxidation Technique ,

Pillai, R. R., Elango, R., Ball, R. O., Kurpad, A. V., & Pencharz, P. B. (2015) · Journal of Nutrition · doi:10.3945/jn.114.208439 · Cited by 44 · see citing works

Lysine Requirement of Healthy, School-Aged Indian Children Determined by the Indicator Amino Acid Oxidation Technique

Pillai, R. R., Elango, R., Muthayya, S., Ball, R. O., Kurpad, A. V., & Pencharz, P. B. (2009) · Journal of Nutrition · doi:10.3945/jn.109.113357 · Cited by 43 · see citing works

Nutritional Considerations for the Vegan Athlete

West, S., Monteyne, A. J., van der Heijden, I., Stephens, F. B., & Wall, B. T. (2023) · Advances in Nutrition · doi:10.1016/j.advnut.2023.04.012 · Cited by 42 · see citing works

Lysine Requirements of Healthy Pregnant Women are Higher During Late Stages of Gestation Compared to Early Gestation

Payne, M., Stephens, T., Lim, K. I., Ball, R. O., Pencharz, P. B., & Elango, R. (2018) · Journal of Nutrition · doi:10.1093/jn/nxx034 · Cited by 37 · see citing works

Mycoprotein ingestion within or without its wholefood matrix results in equivalent stimulation of myofibrillar protein synthesis rates in resting and exercised muscle of young men

West, S., Monteyne, A. J., Whelehan, G., Abdelrahman, D. R., Murton, A. J., Finnigan, T. J. A., Blackwell, J. R., Stephens, F. B., & Wall, B. T. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522003087 · Cited by 35 · see citing works

Rheological and nutritional studies of amaranth enriched wheatchapatti(Indian flat bread)

Banerji, A., Ananthanarayan, L., & Lele, S. S. (2017) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.13361 · Cited by 30 · see citing works

Translating the impact of quality protein maize into improved nutritional status for Ethiopian children: study protocol for a randomized controlled trial

Tessema, M., Gunaratna, N. S., Donato, K., Cohen, J. L., McConnell, M. A., Belayneh, D., Brouwer, I. D., Belachew, T., & Groote, H. D. (2016) · BMC Nutrition · doi:10.1186/s40795-016-0089-z · Cited by 30 · see citing works

20-Week Study of Clinical Outcomes of Over-the-Counter COVID-19 Prophylaxis and Treatment

Margolin, L., Luchins, J., Margolin, D., Margolin, M., & Lefkowitz, S. (2021) · Journal of Evidence-Based Integrative Medicine · doi:10.1177/2515690x211026193 · Cited by 29 · see citing works

Safety assessment of l-lysine oral intake: a systematic review

Hayamizu, K., Oshima, I., Fukuda, Z., Kuramochi, Y., Nagai, Y., Izumo, N., & Nakano, M. (2019) · Amino Acids · doi:10.1007/s00726-019-02697-3 · Cited by 26 · see citing works

High-Level Production of Lysine in the Yeast Saccharomyces cerevisiae by Rational Design of Homocitrate Synthase

Isogai, S., Matsushita, T., Imanishi, H., Koonthongkaew, J., Toyokawa, Y., Nishimura, A., Yi, X., Kazlauskas, R. J., & Takagi, H. (2021) · Applied and Environmental Microbiology · doi:10.1128/aem.00600-21 · Cited by 25 · see citing works

Comprehensive Safety Assessment of ʟ-Lysine Supplementation from Clinical Studies: A Systematic Review

Hayamizu, K., Oshima, I., & Nakano, M. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa218 · Cited by 23 · see citing works

Impact of Lysine-Fortified Wheat Flour on Morbidity and Immunologic Variables among Members of Rural Families in Northwest Syria

Ghosh, S. A., Pellett, P. L., Aw-Hassan, A. A., Mouneime, Y., Smriga, M., & Scrimshaw, N. S. (2008) · Food and Nutrition Bulletin · doi:10.1177/156482650802900302 · Cited by 23 · see citing works

Fifty-Five-Year Personal Experience with Human Nutrition Worldwide

Scrimshaw, N. S. (2007) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.27.061406.093746 · Cited by 22 · see citing works

Limited Supply of Protein and Lysine Is Prevalent among the Poorest Households in Malawi and Exacerbated by Low Protein Quality

Muleya, M., Tang, K., Broadley, M. R., Salter, A. M., & Joy, E. J. M. (2022) · Nutrients · doi:10.3390/nu14122430 · Cited by 18 · see citing works

l-Lysine Acts as a Serotonin Type 4 Receptor Antagonist to Counteract In Vitro and In Vivo the Stimulatory Effect of Serotonergic Agents on Aldosterone Secretion in Man

Duparc, C., André, C., Ménard, J.-F., Godouet-Getti, B., Wils, J., Cailleux, A.-F., Moreau‐Grangé, L., Louiset, E., & Lefèbvre, H. (2017) · Hormone and Metabolic Research · doi:10.1055/s-0042-122781 · Cited by 17 · see citing works

Bioactive constituents, microstructural and nutritional quality characterisation of peanut flat bread

Salve, A. R., & Arya, S. S. (2020) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-020-00406-3 · Cited by 17 · see citing works

Genetic control of grain amino acid composition in a UK soft wheat mapping population

Oddy, J., Chhetry, M., Awal, R., Addy, J., Wilkinson, M., Smith, D. P., King, R., Hall, C., Testa, R., Murray, E., et al. (2023) · The Plant Genome · doi:10.1002/tpg2.20335 · Cited by 15 · see citing works

Metabolic Characteristics and Discriminative Diagnosis of Growth Hormone Deficiency and Idiopathic Short Stature in Preadolescents and Adolescents

Chang, Y., Chen, J., Zhu, H., Huang, R., Wu, J., Lin, Y., Li, Q., Shen, G., & Feng, J. (2024) · Molecules · doi:10.3390/molecules29071661 · Cited by 14 · see citing works

Effect of Eel Biscuit Supplementation on Height of Children with Stunting Aged 36–60 Months: A Pilot Study

Herawati, D. M. D., Asiyah, S., Wiramihardja, S., Fauzia, S., & Sunjaya, D. K. (2020) · Journal of Nutrition and Metabolism · doi:10.1155/2020/2984728 · Cited by 14 · see citing works

Protein quality & amino acid requirements in relation to needs in India

Shivakumar, N., Minocha, S., & Kurpad, A. V. (2018) · The Indian Journal of Medical Research · doi:10.4103/ijmr.ijmr_1688_18 · Cited by 11 · see citing works

Scientific Opinion on the substantiation of health claims related to L‐lysine and immune defence against herpes virus (ID 453), maintenance of normal blood LDL‐cholesterol concentrations (ID 454, 4669), increase in appetite leading to an increase in energy intake (ID 610), contribution to normal protein synthesis (ID 609, 1612), maintenance of normal bone (ID 663, 1915), and increase in calcium absorption leading to an increase in calcium retention (ID 609, 1612) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

EFSA Panel on Dietetic Products, N. A. A. (. (2011) · EFSA Journal · doi:10.2903/j.efsa.2011.2063 · Cited by 10 · see citing works

Quality Differences of Large Yellow Croaker (Pseudosciaena crocea) Cultured in Deep-Water Sea Cages of Two China Regions

Guo, Q., Thanhhoa, T., Jiang, C., Wang, L., Li, B., & Xing, X. (2018) · Journal of Aquaculture Research & Development · doi:10.4172/2155-9546.1000547 · Cited by 9 · see citing works

Improving the regeneration rate of deep lethal mutant protoplasts by fusion to promote efficient L-lysine fermentation

Li, N., Lu, J., Wang, Z., Du, P., Li, P., Su, J., Xiao, J. N., Wang, M., Wang, J., & Wang, R. (2023) · BMC Biotechnology · doi:10.1186/s12896-023-00792-8 · Cited by 8 · see citing works

Protein glycation compromises the bioavailability of milk protein-derived lysine in vivo in healthy adult males: a double-blind, randomized cross-over trial

van Lieshout, G. A. A., Trommelen, J., Nyakayiru, J., van Kranenburg, J. M. X., Senden, J. M., Gijsen, A. P., Verdijk, L. B., Pellikaan, W. F., Bragt, M. C. E., & van Loon, L. J. C. (2025) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2025.01.025 · Cited by 8 · see citing works

Concomitant lysine and phosphorus addition to a wheat gluten protein diet highly amplified growth measures of rats

Ragi, M.-E. E., El-Mallah, C. A., Toufeili, I. A., & Obeid, O. (2018) · Nutrition · doi:10.1016/j.nut.2018.11.009 · Cited by 8 · see citing works

Production of highly nutritious functional food with the supplementation of wheat flour with lysine

Albert, C., Gombos, S., Salamon, R. V., Csiki, Z., Prokisch, J., & Csapó, J. (2017) · Acta Universitatis Sapientiae Alimentaria · doi:10.1515/ausal-2017-0001 · Cited by 8 · see citing works

Low-quality protein modulates inflammatory markers and the response to lipopolysaccharide insult: the case of lysine

El-Mallah, C. A., Ragi, M.-E. E., Eid, A. A., & Obeid, O. (2023) · British Journal Of Nutrition · doi:10.1017/s0007114522004068 · Cited by 5 · see citing works

High-Nutrition Biscuits to Increase Animal Protein in Diets of HIV-Infected Kenyan Women and Their Children: A Study in Progress

Ernst, J. A., Ettyang, G. A., & Neumann, C. G. (2014) · Food and Nutrition Bulletin · doi:10.1177/15648265140354s306 · Cited by 5 · see citing works

Production of a high-nutritional-value functional food, the Update1 bread, with the supplementation of the wheat flour with high-protein-content raw food materials

Csapó, J., & Schobert, N. (2017) · Acta Universitatis Sapientiae Alimentaria · doi:10.1515/ausal-2017-0003 · Cited by 4 · see citing works

Efek tepung ulat sagu (Rhynchophorus ferrugineus) terhadap penurunan kadar malondialdehyde (MDA) pada tikus Wistar dengan diet rendah protein

Lestari, L. A., Sulchan, M., Legowo, A. M., Tjahjono, K., & Juniarto, A. Z. (2021) · AcTion Aceh Nutrition Journal · doi:10.30867/action.v6i2.537 · Cited by 2 · see citing works

Milk Protein Glycation Compromises Postprandial Lysine Bioavailability but does not Modulate Postprandial Muscle Protein Synthesis Rates In Vivo in Males: A Double-blind, Randomized Parallel Trial

van Lieshout, G. A. A., Trommelen, J., Hendriks, F. K., Nyakayiru, J., van Kranenburg, J. M. X., Senden, J. M., Goessens, J. P. B., Verdijk, L. B., Bragt, M. C. E., & van Loon, L. J. C. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.05.032 · Cited by 2 · see citing works

Food Sources and Lysine Intakes of Filipinos: Why Is It Important?

Angeles‐Agdeppa, I., Arias, F. P. S., & Toledo, M. B. (2020) · doi:10.12691/jfnr-8-4-7 · Cited by 1 · see citing works

Effect of Soil Amendment on the Functional and Pasting Properties of False Horn Plantain Flour

Danso, F., Appiah, F. K., & Banful, B. K. B. (2018) · International Journal of Environment Agriculture and Biotechnology · doi:10.22161/ijeab/3.1.36 · Cited by 1 · see citing works

Sago Caterpillar (Rhynchophorus ferrugineus) Flour Improve Insulin-Like Growth Factor 1 (IGF-1) Levels in Low-Protein Diet Rats

Lestari, L. A., & Gunawan, W. B. (2022) · Jurnal Aisyah Jurnal Ilmu Kesehatan · doi:10.30604/jika.v7is1.1300 · Cited by 2 · see citing works

Effects of fortified lysine on the amino acid profile and sensory qualities of deep-fried and dried noodles.

Polpuech, C., Chavasit, V., Srichakwal, P., & PANIANGVAIT, P. (2011) · PubMed · Cited by 1 · see citing works

Development of synthetic cooperative consortia using genetic engineering and adaptive laboratory evolution in yeasts

Guzmán, L. J. B. (2024) · doi:10.21248/gups.83676 · Cited by 1 · see citing works

The fractional synthesis rates of plasma proteins as determined using deuterated water are sensitive to dietary intake of lysine in rats

Tian, Y., Shi, M., Dai, Q., Meng, C., Gu, R., Peng, J. P., Chen, Y., & Jiang, Y. (2018) · Amino Acids · doi:10.1007/s00726-018-2645-0

Application of the Indicator Amino Acid Oxidation Technique to Determine the Protein Quality of Indian Wheat by Studying the Metabolic Availability of Lysine in Healthy Young Adult Men

ZUJAJA-TUL-NOOR, Z.-T.-N. (2018) · TSpace (University of Toronto)

Linear growth failure of Ethiopian children : The role of protein, zinc and mycotoxin intake

Tessema, M. (2020) · doi:10.18174/517748

Importance and nutritive value of plant proteins in human diet

Tu, J., Cheng, P., Brennan, M. A., & Brennan, C. S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95052-7.00004-2

Additional file 1 of Improving the regeneration rate of deep lethal mutant protoplasts by fusion to promote efficient L-lysine fermentation

Li, N., Lu, J., Wang, Z., Du, P., Li, P., Su, J., Xiao, J., Wang, M., Wang, J., & Wang, R. (2023) · Figshare · doi:10.6084/m9.figshare.23689763

Lysine fortification of wheat flour improves selected indices of the nutritional status of predominantly cereal-eating families in Pakistan

Hussain, T., Abbas, S., Khan, M. A., & Scrimshaw, N. S. (2004) · Food and Nutrition Bulletin · doi:10.1177/156482650402500202 · Cited by 81 · see citing works

Impact of Lysine-Fortified Wheat Flour on Morbidity and Immunologic Variables among Members of Rural Families in Northwest Syria

Ghosh, S. A., Pellett, P. L., Aw-Hassan, A. A., Mouneime, Y., Smriga, M., & Scrimshaw, N. S. (2008) · Food and Nutrition Bulletin · doi:10.1177/156482650802900302 · Cited by 23 · see citing works

Nutrition evaluation of wheat flour fortified with lysine and some kinds of the vitamins

Wang, H. (2001) · Chinese Journal of Disease Control and Prevention

THE EFFECT OF LYSINE FORTIFICATION OF IRANIAN BREAD ON THE NUTRITIONAL STATUS OF SCHOOL CHILDREN

Hedayat, H., SHAHBAZI, H., PAYAN, R., Azar, M. M., BAVENDI, M., & Donoso, G. (1973) · Acta Paediatrica · doi:10.1111/j.1651-2227.1973.tb08106.x · Cited by 6 · see citing works

Lysine Fortification of Wheat Bread Fed to Haitian School Children

King, K. W., Sebrell, W. H., Severinghaus, E. L., Storvick, W. O., BERNADOTTE, J., DELVA, H., FOUGERE, W., FOUCALD, J., & Vital, F. (1963) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/12.1.36 · Cited by 33 · see citing works