The Skeletal Muscle Anabolic Response to Plant- versus Animal-Based Protein Consumption

van Vliet, Stephan; Burd, Nicholas A; van Loon, Luc JC

doi:10.3945/jn.114.204305

Cited by 651Muscle metabolism and nutritionMuscle Physiology and DisordersNutrition and Health in Aging

The Skeletal Muscle Anabolic Response to Plant- versus Animal-Based Protein Consumption

Open access

van Vliet, Stephan, Burd, Nicholas A, van Loon, Luc JC·2015·The Journal of Nutrition

DOI 10.3945/jn.114.204305

Open this paper in CoChat — free account Open PDF

Abstract

Clinical and consumer market interest is increasingly directed toward the use of plant-based proteins as dietary components aimed at preserving or increasing skeletal muscle mass. However, recent evidence suggests that the ingestion of the plant-based proteins in soy and wheat results in a lower muscle protein synthetic response when compared with several animal-based proteins. The possible lower anabolic properties of plant-based protein sources may be attributed to the lower digestibility of plant-based sources, in addition to greater splanchnic extraction and subsequent urea synthesis of plant protein-derived amino acids compared with animal-based proteins. The latter may be related to the relative lack of specific essential amino acids in plant- as opposed to animal-based proteins. Furthermore, most plant proteins have a relatively low leucine content, which may further reduce their anabolic properties when compared with animal proteins. However, few studies have actually assessed the postprandial muscle protein synthetic response to the ingestion of plant proteins, with soy and wheat protein being the primary sources studied. Despite the proposed lower anabolic properties of plant vs. animal proteins, various strategies may be applied to augment the anabolic properties of plant proteins. These may include the following: 1) fortification of plant-based protein sources with the amino acids methionine, lysine, and/or leucine; 2) selective breeding of plant sources to improve amino acid profiles; 3) consumption of greater amounts of plant-based protein sources; or 4) ingesting multiple protein sources to provide a more balanced amino acid profile. However, the efficacy of such dietary strategies on postprandial muscle protein synthesis remains to be studied. Future research comparing the anabolic properties of a variety of plant-based proteins should define the preferred protein sources to be used in nutritional interventions to support skeletal muscle mass gain or maintenance in both healthy and clinical populations.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.3945/jn.114.204305

Cites

100 of 100 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Plant protein, including soy, is deficient in specific essential amino acids.
“Plant protein, including soy, is deficient in specific EAAs [15,52].”
From Animal Protein versus Plant Protein in Supporting Lean Mass and Muscle Strength: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2021) · cites this paper as [15]
Amino acids from animal-based sources have a more pronounced anabolic effect than those from plant-based sources.
“Amino acids derived from animal-based sources have a more pronounced anabolic effect than those derived from plant-based sources179.”
From Sarcopenic obesity in older adults: a clinical overview (2024) · cites this paper as [179]
Blending plant-based protein sources is a suggested method to obviate essential amino acid deficiencies.
“Blending plant-based protein sources is a suggested method to obviate EAA deficiencies [71,83].”
From Nutritional Considerations for the Vegan Athlete (2023) · cites this paper as [71]
The robust postexercise MPS responses to milk, egg, and meat-derived proteins have been attributed to their high essential amino acid content, particularly leucine, a lack of notable amino acid deficiencies, rapid digestibility, and high total digestibility/absorbability.
“This has been attributed to their high essential amino acid (EAA) content [69], particularly leucine [70], a lack of any notable amino acid deficiencies [71], rapid digestibility [72], and a high total digestibility/absorbability and therefore availability in the circulation (ie, ‘bioavailability’) [72].”
From Nutritional Considerations for the Vegan Athlete (2023) · cites this paper as [71]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The underappreciated role of muscle in health and disease
Wolfe, R. R. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.3.475 · Cited by 1,561 · see citing works
Slow and fast dietary proteins differently modulate postprandial protein accretion
Boirie, Y., Dangin, M., Gachon, P., Vasson, M.-P., Maubois, J.-L., & Beaufrère, B. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14930 · Cited by 1,453 · see citing works
Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study
Houston, D. K., Nicklas, B. J., Ding, J., Harris, T. B., Tylavsky, F. A., Newman, A. B., Lee, J. S., Sahyoun, N. R., Visser, M., & Kritchevsky, S. B. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.1.150 · Cited by 1,214 · see citing works
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
Cuthbertson, D., Smith, K., Babraj, J., Leese, G., Waddell, T., Atherton, P., Wackerhage, H., Taylor, P. M., & Rennie, M. J. (2005) · The FASEB Journal · doi:10.1096/fj.04-2640fje · Cited by 1,211 · see citing works
Sustainability of meat-based and plant-based diets and the environment
Pimentel, D., & Pimentel, M. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.3.660s · Cited by 1,021 · see citing works
Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men
Tang, J. E., Moore, D. R., Kujbida, G. W., Tarnopolsky, M. A., & Phillips, S. M. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00076.2009 · Cited by 998 · see citing works
Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men
Moore, D. R., Robinson, M. J., Fry, J. L., Tang, J. E., Glover, E. I., Wilkinson, S. B., Prior, T., Tarnopolsky, M. A., & Phillips, S. M. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26401 · Cited by 973 · see citing works
A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly
Katsanos, C. S., Kobayashi, H., Sheffield-Moore, M., Aarsland, A., & Wolfe, R. R. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00488.2005 · Cited by 923 · see citing works
Hempseed as a nutritional resource: An overview
Callaway, J. C. (2004) · Euphytica · doi:10.1007/s10681-004-4811-6 · Cited by 910 · see citing works
Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults
Volpi, E., Kobayashi, H., Sheffield-Moore, M., Mittendorfer, B., & Wolfe, R. R. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.2.250 · Cited by 846 · see citing works
Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis
Cermak, N. M., Res, P. T., de Groot, L. C., Saris, W. H., & van Loon, L. J. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.037556 · Cited by 827 · see citing works
Self-citation
Plant proteins in relation to human protein and amino acid nutrition
Young, V., & Pellett, P. (1994) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/59.5.1203s · Cited by 717 · see citing works
Impact of Antinutritional Factors in Food Proteins on the Digestibility of Protein and the Bioavailability of Amino Acids and on Protein Quality
Gilani, G. S., Xiao, C. W., & Cockell, K. A. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512002371 · Cited by 686 · see citing works
Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men
Pennings, B., Boirie, Y., Senden, J. M., Gijsen, A. P., Kuipers, H., & van Loon, L. J. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.008102 · Cited by 656 · see citing works
Self-citation
The digestion rate of protein is an independent regulating factor of postprandial protein retention
Dangin, M., Boirie, Y., Garcia-Rodenas, C., Gachon, P., Fauquant, J., Callier, P., Ballèvre, O., & Beaufrère, B. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.2.e340 · Cited by 572 · see citing works
The Protein Digestibility–Corrected Amino Acid Score
Schaafsma, G. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.7.1865s · Cited by 537 · see citing works
Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage
Wilkinson, S. B., Tarnopolsky, M. A., MacDonald, M. J., MacDonald, J. R., Armstrong, D., & Phillips, S. M. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.4.1031 · Cited by 530 · see citing works
Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise
Witard, O. C., Jackman, S. R., Breen, L., Smith, K., Selby, A., & Tipton, K. D. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.055517 · Cited by 517 · see citing works
Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters
Hartman, J. W., Tang, J. E., Wilkinson, S. B., Tarnopolsky, M. A., Lawrence, R. L., Fullerton, A. V., & Phillips, S. M. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.2.373 · Cited by 498 · see citing works
Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis
Areta, J. L., Burke, L. M., Ross, M. L., Camera, D. M., West, D. W. D., Broad, E. M., Jeacocke, N. A., Moore, D. R., Stellingwerff, T., Phillips, S. M., et al. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.244897 · Cited by 495 · see citing works
Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle
Biolo, G., Declan Fleming, R. Y., & Wolfe, R. R. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117731 · Cited by 442 · see citing works
Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults
Mamerow, M. M., Mettler, J. A., English, K. L., Casperson, S. L., Arentson-Lantz, E., Sheffield-Moore, M., Layman, D. K., & Paddon-Jones, D. (2014) · The Journal of Nutrition · doi:10.3945/jn.113.185280 · Cited by 438 · see citing works
Evaluating the environmental impact of various dietary patterns combined with different food production systems
Baroni, L., Cenci, L., Tettamanti, M., & Berati, M. (2006) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602522 · Cited by 420 · see citing works
Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia
Rieu, I., Balage, M., Sornet, C., Giraudet, C., Pujos, E., Grizard, J., Mosoni, L., & Dardevet, D. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.110742 · Cited by 410 · see citing works
Food balance sheets.
Kelly, A., Becker, W. G., & Helsing, E. (1991) · PubMed · Cited by 404 · see citing works
Role of dietary protein in the sarcopenia of aging.
Paddon-Jones, D., Short, K., Campbell, W., Volpi, E., & Wolfe, R. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.5.1562s · Cited by 403 · see citing works
Exogenous amino acids stimulate net muscle protein synthesis in the elderly.
Volpi, E., Ferrando, A. A., Yeckel, C. W., Tipton, K. D., & Wolfe, R. R. (1998) · Journal of Clinical Investigation · doi:10.1172/jci939 · Cited by 390 · see citing works
Anabolic Resistance of Muscle Protein Synthesis with Aging
Burd, N. A., Gorissen, S. H., & van Loon, L. J. C. (2013) · Exercise and Sport Sciences Reviews · doi:10.1097/jes.0b013e318292f3d5 · Cited by 384 · see citing works
Self-citation
Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein
Koopman, R., Crombach, N., Gijsen, A. P., Walrand, S., Fauquant, J., Kies, A. K., Lemosquet, S., Saris, W. H. M., Boirie‌, Y., & van Loon, L. J. C. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27474 · Cited by 380 · see citing works
Aging, exercise, and muscle protein metabolism
Koopman, R., & van Loon, L. J. C. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91551.2008 · Cited by 371 · see citing works
Protein quality assessment: impact of expanding understanding of protein and amino acid needs for optimal health
Millward, D. J., Layman, D. K., Tomé, D., & Schaafsma, G. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.5.1576s · Cited by 359 · see citing works
Moderating the portion size of a protein-rich meal improves anabolic efficiency in young and elderly
Symons, T., Sheffield-Moore, M., Wolfe, R. R., & Paddon-Jones, D. (2009) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2009.06.369 · Cited by 352 · see citing works
Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men1–3
Burd, N. A., West, D. W. D., Moore, D. R., Atherton, P. J., Staples, A. W., Prior, T., Tang, J. E., Rennie, M. J., Baker, S. K., & Phillips, S. M. (2011) · The Journal of Nutrition · doi:10.3945/jn.110.135038 · Cited by 325 · see citing works
Self-citation
Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells
Atherton, P. J., Smith, K., Etheridge, T., Rankin, D., & Rennie, M. J. (2010) · Amino Acids · doi:10.1007/s00726-009-0377-x · Cited by 323 · see citing works
Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise
Moore, D. R., Tang, J. E., Burd, N. A., Rerecich, T., Tarnopolsky, M. A., & Phillips, S. M. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.164087 · Cited by 322 · see citing works
Self-citation
Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects
Koopman, R., Wagenmakers, A. J. M., MANDERS, R. J. F., Zorenc, A. H. G., Senden, J. M., Gorselink, M., KEIZER, H. A., & van Loon, L. J. C. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00413.2004 · Cited by 316 · see citing works
Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men
Churchward‐Venne, T. A., Burd, N. A., Mitchell, C. J., West, D. W. D., Philp, A., Marcotte, G. R., Baker, S. K., Baar, K., & Phillips, S. M. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.228833 · Cited by 314 · see citing works
Self-citation
Exercising before protein intake allows for greater use of dietary protein–derived amino acids for de novo muscle protein synthesis in both young and elderly men
Pennings, B., Koopman, R., Beelen, M., Senden, J. M., Saris, W. H., & van Loon, L. J. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29649 · Cited by 311 · see citing works
Self-citation
Postprandial Kinetics of Dietary Amino Acids Are the Main Determinant of Their Metabolism after Soy or Milk Protein Ingestion in Humans
Bos, C., Gaudichon, C., Pueyo, M. E., Morens, C., Tomé, D., Metges, C. C., Petzke, K. J., Everwand, J., & Benamouzig, R. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.5.1308 · Cited by 309 · see citing works
Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise
Tipton, K. D., Elliott, T. A., Cree, M. G., Aarsland, A. A., Sanford, A. P., & Wolfe, R. R. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00166.2006 · Cited by 307 · see citing works
Diet and the environment: does what you eat matter?
Marlow, H. J., Hayes, W. K., Soret, S., Carter, R. L., Schwab, E. R., & Sabaté, J. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.26736z · Cited by 301 · see citing works
The Role of Leucine in the Regulation of Protein Metabolism
Garlick, P. J. (2005) · Journal of Nutrition · doi:10.1093/jn/135.6.1553s · Cited by 301 · see citing works
Regulation of Muscle Protein by Amino Acids
Wolfe, R. R. (2002) · The Journal of Nutrition · doi:10.1093/jn/131.10.3219s · Cited by 288 · see citing works
Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men.
Verhoeven, S., Vanschoonbeek, K., Verdijk, L., Koopman, R., Wodzig, W., Dendale, P., & van Loon, L. V. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26668 · Cited by 286 · see citing works
Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men
Yang, Y., Churchward-Venne, T. A., Burd, N. A., Breen, L., Tarnopolsky, M. A., & Phillips, S. M. (2012) · Nutrition & Metabolism · doi:10.1186/1743-7075-9-57 · Cited by 286 · see citing works
Self-citation
Nutritional quality of legume seeds as affected by some physical treatments, Part 1: Protein quality evaluation
Khattab, R. Y., Arntfield, S. D., & Nyachoti, C. M. (2009) · LWT - Food Science and Technology · doi:10.1016/j.lwt.2009.02.008 · Cited by 250 · see citing works
Nonessential amino acids are not necessary to stimulate net muscle protein synthesis in healthy volunteers
Tipton, K. (1999) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(98)00087-4 · Cited by 231 · see citing works
Leucine Supplementation Enhances Skeletal Muscle Recovery in Rats Following Exercise
Anthony, J. C., Anthony, T. G., & Layman, D. K. (1999) · Journal of Nutrition · doi:10.1093/jn/129.6.1102 · Cited by 226 · see citing works
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein
Paddon-Jones, D., Sheffield-Moore, M., Katsanos, C. S., Zhang, X.-J., & Wolfe, R. R. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2005.10.006 · Cited by 223 · see citing works
Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men
Wall, B. T., Hamer, H. M., de Lange, A., Kiskini, A., Groen, B. B. L., Senden, J. M. G., Gijsen, A. P., Verdijk, L. B., & van Loon, L. J. C. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2012.09.002 · Cited by 220 · see citing works
The 2013 FAO report on dietary protein quality evaluation in human nutrition: Recommendations and implications
Leser, S. (2013) · Nutrition Bulletin · doi:10.1111/nbu.12063 · Cited by 206 · see citing works
Effects of an omnivorous diet compared with a lactoovovegetarian diet on resistance-training-induced changes in body composition and skeletal muscle in older men
Campbell, W. W., Barton, M. L., Cyr-Campbell, D., Davey, S. L., Beard, J. L., Parise, G., & Evans, W. J. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.6.1032 · Cited by 190 · see citing works
Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein
Casperson, S. L., Sheffield‐Moore, M., Hewlings, S. J., & Paddon‐Jones, D. (2012) · Clinical Nutrition · doi:10.1016/j.clnu.2012.01.005 · Cited by 187 · see citing works
Postprandial Stimulation of Muscle Protein Synthesis in Old Rats Can Be Restored by a Leucine-Supplemented Meal
Dardevet, D. P., Sornet, C., Bayle, G., Prugnaud, J., Pouyet, C., & Grizard, J. (2002) · Journal of Nutrition · doi:10.1093/jn/132.1.95 · Cited by 185 · see citing works
Whey protein supplementation during resistance training augments lean body mass
Volek, J. S., Volk, B. M., Gómez, A. L., Kunces, L. J., Kupchak, B. R., Freidenreich, D. J., Aristizabal, J. C., Saenz, C., Dunn-Lewis, C., Ballard, K. D., et al. (2013) · Journal of the American College of Nutrition · doi:10.1080/07315724.2013.793580 · Cited by 181 · see citing works
The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance
Joy, J. M., Lowery, R. P., Wilson, J. M., Purpura, M., De Souza, E. O., Wilson, S. M., Kalman, D. S., Dudeck, J. E., & Jäger, R. (2013) · Nutrition Journal · doi:10.1186/1475-2891-12-86 · Cited by 179 · see citing works
The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in rats
Norton, L. E., Layman, D. K., Bunpo, P., Anthony, T. G., Brana, D. V., & Garlick, P. J. (2009) · The Journal of Nutrition · doi:10.3945/jn.108.103853 · Cited by 178 · see citing works
Protein blend ingestion following resistance exercise promotes human muscle protein synthesis
Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Fry, C. S., Borack, M. S., Cope, M. B., Mukherjea, R., et al. (2013) · The Journal of Nutrition · doi:10.3945/jn.112.168021 · Cited by 178 · see citing works
Dietary Protein Digestion and Absorption Rates and the Subsequent Postprandial Muscle Protein Synthetic Response Do Not Differ between Young and Elderly Men ,
Koopman, R., Walrand, S., Beelen, M., Gijsen, A. P., Kies, A. K., Boirie, Y., Saris, W. H. M., & van Loon, L. J. C. (2009) · The Journal of Nutrition · doi:10.3945/jn.109.109173 · Cited by 167 · see citing works
Minced beef is more rapidly digested and absorbed than beef steak, resulting in greater postprandial protein retention in older men
Pennings, B., Groen, B. B., van Dijk, J.-W., de Lange, A., Kiskini, A., Kuklinski, M., Senden, J. M., & van Loon, L. J. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.051201 · Cited by 167 · cited 1× · see citing works
“In addition, this work has shown that a total of 50–70% of the dietary protein–derived AAs from milk and beef protein become available in systemic circulation when assessed over a 5- to 6-h postprandial period (17, 22, 29).”
Background
Prolonged Leucine Supplementation Does Not Augment Muscle Mass or Affect Glycemic Control in Elderly Type 2 Diabetic Men
Leenders, M., Verdijk, L. B., van der Hoeven, L., van Kranenburg, J. M. X., Hartgens, F., Wodzig, W. K. W. H., Saris, W. H. M., & van Loon, L. J. C. (2011) · Journal of Nutrition · doi:10.3945/jn.111.138495 · Cited by 159 · see citing works
Dietary protein and resistance training effects on muscle and body composition in older persons
Campbell, W. W., & Leidy, H. J. (2007) · Journal of the American College of Nutrition · doi:10.1080/07315724.2007.10719650 · Cited by 148 · see citing works
Peripheral and Splanchnic Metabolism of Dietary Nitrogen Are Differently Affected by the Protein Source in Humans as Assessed by Compartmental Modeling
Fouillet, H., Mariotti, F., Gaudichon, C., Bos, C., & Tomé, D. (2002) · Journal of Nutrition · doi:10.1093/jn/132.1.125 · Cited by 147 · see citing works
Effect of protein source on resistive-training-induced changes in body composition and muscle size in older men
Haub, M. D., Wells, A. M., Tarnopolsky, M. A., & Campbell, W. W. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.3.511 · Cited by 146 · see citing works
Postprandial metabolic utilization of wheat protein in humans
Bos, C., Juillet, B., Fouillet, H., Turlan, L., Daré, S., Luengo, C., Ntounda, R., Benamouzig, R., Gausserès, N., Tomé, D., et al. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.87 · Cited by 141 · see citing works
Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men
Tang, J. E., Manolakos, J. J., Kujbida, G. W., Lysecki, P. J., Moore, D. R., & Phillips, S. M. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-076 · Cited by 130 · see citing works
Leucine content of dietary proteins is a determinant of postprandial skeletal muscle protein synthesis in adult rats
Norton, L. E., Wilson, G. J., Layman, D. K., Moulton, C. J., & Garlick, P. J. (2012) · Nutrition & Metabolism · doi:10.1186/1743-7075-9-67 · Cited by 126 · see citing works
A meta-analysis of community-based studies on quality protein maize
Gunaratna, N. S., Groote, H. D., Nestel, P., Pixley, K. V., & McCabe, G. P. (2009) · Food Policy · doi:10.1016/j.foodpol.2009.11.003 · Cited by 126 · see citing works
Nutrient-rich meat proteins in offsetting age-related muscle loss
Phillips, S. M. (2012) · Meat Science · doi:10.1016/j.meatsci.2012.04.027 · Cited by 122 · see citing works
Soy versus whey protein bars: Effects on exercise training impact on lean body mass and antioxidant status
Brown, E. C., DiSilvestro, R. A., Babaknia, A., & Devor, S. T. (2004) · Nutrition Journal · doi:10.1186/1475-2891-3-22 · Cited by 122 · see citing works
Leucine as a pharmaconutrient in health and disease
van Loon, L. J. C. (2012) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e32834d617a · Cited by 119 · see citing works
The anabolic response to resistance exercise and a protein-rich meal is not diminished by age
Symonsi, T. B., Sheffield-Moore, M., Mamerow, M. M., Wolfe, R. R., & Paddon-Jones, D. (2011) · The Journal of nutrition, health and aging · doi:10.1007/s12603-010-0319-z · Cited by 112 · see citing works
Dose-dependent responses of myofibrillar protein synthesis with beef ingestion are enhanced with resistance exercise in middle-aged men
Robinson, M. J., Burd, N. A., Breen, L., Rerecich, T., Yang, Y., Hector, A. J., Baker, S. K., & Phillips, S. M. (2013) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2012-0092 · Cited by 109 · see citing works
Self-citation
Supplementation of soy protein with branched-chain amino acids alters protein metabolism in healthy elderly and even more in patients with chronic obstructive pulmonary disease
ENGELEN, M. P. K. J., Rutten, E. P. A., de Castro, C. L. N., Wouters, E. F. �., Schols, A. M. W. J., & Deutz, N. E. P. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.431 · Cited by 108 · see citing works
Dietary animal protein intake: association with muscle mass index in older women.
Lord, C., Chaput, J., Aubertin‐Leheudre, M., Labonté, M., & Dionne, I. J. (2007) · PubMed · Cited by 82 · see citing works
Lysine fortification of wheat flour improves selected indices of the nutritional status of predominantly cereal-eating families in Pakistan
Hussain, T., Abbas, S., Khan, M. A., & Scrimshaw, N. S. (2004) · Food and Nutrition Bulletin · doi:10.1177/156482650402500202 · Cited by 81 · see citing works
The science of muscle hypertrophy: making dietary protein count
Phillips, S. M. (2011) · Proceedings of the Nutrition Society · doi:10.1017/s002966511000399x · Cited by 81 · see citing works
A randomised study on the effects of fish protein supplement on glucose tolerance, lipids and body composition in overweight adults
Vikøren, L. A. S., Nygard, O. K., Lied, E., Rostrup, E., & Gudbrandsen, O. A. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512001717 · Cited by 76 · see citing works
The effectiveness of quality protein maize in improving the nutritional status of young children in the Ethiopian Highlands
Akalu, G., Taffesse, S., Gunaratna, N. S., & De Groote, H. (2010) · Food and Nutrition Bulletin · doi:10.1177/156482651003100304 · Cited by 70 · see citing works
Available versus digestible dietary amino acids
Rutherfurd, S. M., & Moughan, P. J. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512002528 · Cited by 67 · see citing works
Relationship between animal protein intake and muscle mass index in healthy women
Aubertin‐Leheudre, M., & Adlercreutz, H. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509991310 · Cited by 65 · see citing works
Role of specific dietary amino acids in clinical conditions
Jonker, R., Engelen, M., & Deutz, N. (2012) · British Journal of Nutrition · doi:10.1017/s0007114512002358 · Cited by 65 · see citing works
Nutritional assessment of transgenic lysine‐rich maize compared with conventional quality protein maize
Tang, M., He, X., Luo, Y., et al. (2013) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.5845 · Cited by 60 · see citing works
What is the relationship between the acute muscle protein synthesis response and changes in muscle mass?
Mitchell, C. J., Churchward‐Venne, T. A., Cameron‐Smith, D., & Phillips, S. M. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00609.2014 · Cited by 59 · see citing works
Lysine-fortified wheat flour improves the nutritional and immunological status of wheat-eating families in northern China
Zhao, W., Zhai, F., Zhang, D., An, Y., Liu, Y., He, Y., Ge, K., & Scrimshaw, N. S. (2004) · Food and Nutrition Bulletin · doi:10.1177/156482650402500203 · Cited by 58 · see citing works
Role of leucine and other amino acids in regulating protein metabolism in vivo
Frexes-Steed, M., Lacy, D. B., Collins, J. J., & Abumrad, N. N. (1992) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1992.262.6.e925 · Cited by 58 · see citing works
Absorption kinetics are a key factor regulating postprandial protein metabolism in response to qualitative and quantitative variations in protein intake
Fouillet, H., Juillet, B., Gaudichon, C., Mariotti, F., Tomé, D., & Bos, C. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00281.2009 · Cited by 57 · see citing works
Effect of protein source and resistance training on body composition and sex hormones
Kalman, D., Feldman, S., Martínez, M. C. G., Krieger, D., & Tallon, M. J. (2007) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-4-4 · Cited by 56 · see citing works
The production of intrinsically labeled milk and meat protein is feasible and provides functional tools for human nutrition research
Pennings, B., Pellikaan, W. F., Senden, J. M., van Vuuren, A. M., Sikkema, J., & van Loon, L. J. C. (2011) · Journal of Dairy Science · doi:10.3168/jds.2011-4451 · Cited by 53 · see citing works
Substantial Differences between Organ and Muscle Specific Tracer Incorporation Rates in a Lactating Dairy Cow
Burd, N. A., Hamer, H. M., Pennings, B., Pellikaan, W. F., Senden, J. M., Gijsen, A. P., & van Loon, L. J. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068109 · Cited by 44 · see citing works
Self-citation
The single biopsy approach is reliable for the measurement of muscle protein synthesis rates in vivo in older men
Burd, N. A., Pennings, B., Groen, B. B. L., Gijsen, A. P., Senden, J. M., & van Loon, L. J. C. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00513.2012 · Cited by 38 · see citing works
Self-citation
Nutrition studies in Thailand. II. Effects of fortification of rice with lysine, threonine, thiamin, riboflavin, vitamin A, and iron on preschool children
Gershoff, S., McGandy, R. B., Suttapreyasri, D., Promkutkao, C., Nondasuta, A., Pisolyabutra, U., Tantiwongse, P., & Viravaidhaya, V. (1977) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/30.7.1185 · Cited by 34 · see citing works
The protein sparing function of the gut and the quality of food protein
Soeters, P. B., de JONG, C. H., & Deutz, N. E. P. (2001) · Clinical Nutrition · doi:10.1054/clnu.2000.0376 · Cited by 34 · see citing works
Need for measures of satellite cell activation along with muscle protein synthesis
CAMERA, D. M., & Hawley, J. A. (2015) · Research Bank (Australian Catholic University) · Cited by 33 · see citing works
Study of Mycoprotein Production Using Fusarium oxysporum PTCC 5115 and Reduction of its RNA Content
Ahangi, Z., Shojaosadati, S. A., & Nikoopour, H. (2008) · Pakistan Journal of Nutrition · doi:10.3923/pjn.2008.240.243 · Cited by 16 · see citing works
Effect of the Quality of Dietary Amino Acids Composition on the Urea Synthesis in Rats
Tujioka, K., Ohsumi, M., HAYASE, K., & Yokogoshi, H. (2011) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.57.48 · Cited by 13 · see citing works
A specific protein-enriched enteral formula decreases cortisolemia and improves plasma albumin and amino acid concentrations in elderly patients
Olza, J., Mesa, M., Poyatos, R., Aguilera, C., Moreno-Torres, R., Pérez, M., de la Cruz, A. J. P., & Gil, Á. (2010) · Nutrition and Metabolism · doi:10.1186/1743-7075-7-58 · Cited by 6 · see citing works
[Biological evaluation of a protein mixture intended for enteral nutrition].
Olza, J., Foulquie, J. P., Valero, G. U., et al. (2008) · PubMed · Cited by 6 · see citing works
Various sources of animal protein intake and their association with muscle mass index and insulin resistance in overweight postmenopausal women
Maltais, M. L., Leblanc, S., Archambault-Therrien, C., Jean, B., Bobeuf, F., & Dionne, I. J. (2013) · International Journal of Nutrition and Metabolism · doi:10.5897/ijnam12.019 · Cited by 4 · see citing works
The Results and Interpretation of Three Field Trials of Lysine Fortification of Cereals
Austin, J. E., Habicht, J., Milner, M., et al. (1984) · Cited by 3 · see citing works

Flagged first, then by citations

Research works printed but not linked: 2

[26]26. Symons TB, Sheffield-Moore M, Wolfe RR, Paddon-Jones D. A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc 2009;109:1582-6.
[45]45. WHO/FAO/UNU. Protein and amino acid requirements in human nutrition: report of a joint WHO/FAO/UNU expert consultation. World Health Organ Tech Rep Ser 2007;935:1-265.

Sorted by citations

Protein content and amino acid composition of commercially available plant-based protein isolates
Gorissen, S. H. M., Crombag, J. J. R., Senden, J. M. G., Waterval, W. A. H., Bierau, J., Verdijk, L. B., & van Loon, L. J. C. (2018) · Amino Acids · doi:10.1007/s00726-018-2640-5 · Cited by 1,169 · see citing works
Self-citation
Dietary protein intake and human health
Wu, G. (2016) · Food & Function · doi:10.1039/c5fo01530h · Cited by 748 · see citing works
Does nutrition play a role in the prevention and management of sarcopenia?
Robinson, S. M., Reginster, J. Y., Rizzoli, R., Shaw, S. C., Kanis, J. A., Bautmans, I., Bischoff-Ferrari, H., Bruyère, O., Cesari, M., Dawson-Hughes, B., et al. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2017.08.016 · Cited by 491 · see citing works
Self-citation
The Role of the Anabolic Properties of Plant- versus Animal-Based Protein Sources in Supporting Muscle Mass Maintenance: A Critical Review
Berrazaga, I., Micard, V., Gueugneau, M., & Walrand, S. (2019) · Nutrients · doi:10.3390/nu11081825 · Cited by 477 · see citing works
Sarcopenic obesity in older adults: a clinical overview
Prado, C. M., Batsis, J. A., Donini, L. M., Gonzalez, M. C., & Siervo, M. (2024) · Nature Reviews Endocrinology · doi:10.1038/s41574-023-00943-z · Cited by 355 · see citing works
Ingestion of wheat protein increases in vivo muscle protein synthesis rates in healthy older men in a randomized trial
Gorissen, S. H., Horstman, A. M., Franssen, R., Crombag, J. J., Langer, H., Bierau, J., Respondek, F., & van Loon, L. J. (2016) · The Journal of Nutrition · doi:10.3945/jn.116.231340 · Cited by 221 · see citing works
Protein Intake and Muscle Health in Old Age: From Biological Plausibility to Clinical Evidence
Landi, F., Calvani, R., Tosato, M., Martone, A., Ortolani, E., Savera, G., D’Angelo, E., Sisto, A., & Marzetti, E. (2016) · Nutrients · doi:10.3390/nu8050295 · Cited by 218 · see citing works
Exercise and nutrition strategies to counteract sarcopenic obesity
Trouwborst, I., Verreijen, A., Memelink, R., Massanet, P., Boirie, Y., Weijs, P., & Tieland, M. (2018) · Nutrients · doi:10.3390/nu10050605 · Cited by 210 · see citing works
Characterising the muscle anabolic potential of dairy, meat and plant-based protein sources in older adults
Gorissen, S. H. M., & Witard, O. C. (2018) · Proceedings of the Nutrition Society · doi:10.1017/s002966511700194x · Cited by 221 · see citing works
Sources and amounts of animal, dairy, and plant protein intake of US adults in 2007-2010.
Pasiakos, S., Agarwal, S., Lieberman, H., & Fulgoni, V. (2015) · Nutrients · doi:10.3390/nu7085322 · Cited by 211 · see citing works
Sarcopenic Obesity: Epidemiologic Evidence, Pathophysiology, and Therapeutic Perspectives
Koliaki, C., Liatis, S., Dalamaga, M., & Kokkinos, A. (2019) · Current Obesity Reports · doi:10.1007/s13679-019-00359-9 · Cited by 176 · see citing works
The impact of protein quality on the promotion of resistance exercise-induced changes in muscle mass
Phillips, S. M. (2016) · Nutrition & Metabolism · doi:10.1186/s12986-016-0124-8 · Cited by 168 · see citing works
The anabolic response to plant-based protein ingestion
Pinckaers, P. J. M., Trommelen, J., Snijders, T., & van Loon, L. J. C. (2021) · Sports Medicine · doi:10.1007/s40279-021-01540-8 · Cited by 170 · see citing works
Animal Protein versus Plant Protein in Supporting Lean Mass and Muscle Strength: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lim, M. T., Pan, B. J., Toh, D. W. K., Sutanto, C. N., & Kim, J. E. (2021) · Nutrients · doi:10.3390/nu13020661 · Cited by 164 · see citing works
“EAAs are known to stimulate the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, triggering a rise in MPS [53,54].”
BackgroundInfluential
Muscle and Bone Health in Postmenopausal Women: Role of Protein and Vitamin D Supplementation Combined with Exercise Training
Agostini, D., Donati Zeppa, S., Lucertini, F., Annibalini, G., Gervasi, M., Ferri Marini, C., Piccoli, G., Stocchi, V., Barbieri, E., & Sestili, P. (2018) · Nutrients · doi:10.3390/nu10081103 · Cited by 151 · see citing works
Leucine supplementation enhances integrative myofibrillar protein synthesis in free-living older men consuming lower- and higher-protein diets: a parallel-group crossover study
Murphy, C. H., Saddler, N. I., Devries, M. C., McGlory, C., Baker, S. K., & Phillips, S. M. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.136424 · Cited by 133 · see citing works
The effects of dietary protein intake on appendicular lean mass and muscle function in elderly men: A 10-wk randomized controlled trial
Mitchell, C. J., Milan, A. M., Mitchell, S. M., Zeng, N., Ramzan, F., Sharma, P., Knowles, S. O., Roy, N. C., Sjödin, A., Wagner, K.-H., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.117.160325 · Cited by 132 · see citing works
Protein Considerations for Optimising Skeletal Muscle Mass in Healthy Young and Older Adults
Witard, O., Wardle, S., Macnaughton, L., Hodgson, A., & Tipton, K. (2016) · Nutrients · doi:10.3390/nu8040181 · Cited by 132 · see citing works
High-Protein Plant-Based Diet Versus a Protein-Matched Omnivorous Diet to Support Resistance Training Adaptations: A Comparison Between Habitual Vegans and Omnivores
Hevia-Larraín, V., Gualano, B., Longobardi, I., Gil, S., Fernandes, A. L., Costa, L. A. R., Pereira, R. M. R., Artioli, G. G., Phillips, S. M., & Roschel, H. (2021) · Sports Medicine · doi:10.1007/s40279-021-01434-9 · Cited by 132 · see citing works
No Difference Between the Effects of Supplementing With Soy Protein Versus Animal Protein on Gains in Muscle Mass and Strength in Response to Resistance Exercise
Messina, M., Lynch, H., Dickinson, J. M., & Reed, K. E. (2018) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2018-0071 · Cited by 120 · see citing works
Mycoprotein ingestion stimulates protein synthesis rates to a greater extent than milk protein in rested and exercised skeletal muscle of healthy young men: a randomized controlled trial
Monteyne, A. J., Coelho, M. O., Porter, C., Abdelrahman, D. R., Jameson, T. S., Jackman, S. R., Blackwell, J. R., Finnigan, T. J., Stephens, F. B., Dirks, M. L., et al. (2020) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa092 · Cited by 110 · see citing works
Effect of a High-Protein Diet Versus Standard-Protein Diet on Weight Loss and Biomarkers of Metabolic Syndrome: A Randomized Clinical Trial
Campos-Nonato, I., Hernandez, L., & Barquera, S. (2017) · Obesity Facts · doi:10.1159/000471485 · Cited by 97 · see citing works
No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males
Pinckaers, P. J. M., Kouw, I. W. K., Hendriks, F. K., van Kranenburg, J. M. X., de Groot, L. C. P. G. M., Verdijk, L. B., Snijders, T., & van Loon, L. J. C. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521000635 · Cited by 76 · see citing works
Self-citation
The muscle protein synthetic response to the ingestion of a plant-derived protein blend does not differ from an equivalent amount of milk protein in healthy, young males
Pinckaers, P. J., Kouw, I. W., Gorissen, S. H., Houben, L. H., Senden, J. M., Wodzig, W. K., de Groot, L. C., Verdijk, L. B., Snijders, T., & van Loon, L. J. (2022) · The Journal of Nutrition · doi:10.1093/jn/nxac222 · Cited by 70 · see citing works
Self-citation
A focus on leucine in the nutritional regulation of human skeletal muscle metabolism in ageing, exercise and unloading states
Ely, I. A., Phillips, B. E., Smith, K., Wilkinson, D. J., Piasecki, M., Breen, L., Larsen, M. S., & Atherton, P. J. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.08.010 · Cited by 64 · see citing works
Vegan and omnivorous high protein diets support comparable daily myofibrillar protein synthesis rates and skeletal muscle hypertrophy in young adults
Monteyne, A. J., Coelho, M. O. C., Murton, A. J., Abdelrahman, D. R., Blackwell, J. R., Koscien, C. P., Knapp, K. M., Fulford, J., Finnigan, T. J. A., Dirks, M. L., et al. (2023) · The Journal of Nutrition · doi:10.1016/j.tjnut.2023.02.023 · Cited by 64 · see citing works
Consumer acceptance of microalgae as a novel food‐where are we now? And how to get further
Olsen, M. L., Olsen, K., & Jensen, P. E. (2024) · Physiologia Plantarum · doi:10.1111/ppl.14337 · Cited by 62 · see citing works
Plant-based food patterns to stimulate muscle protein synthesis and support muscle mass in humans: a narrative review
Nichele, S., Phillips, S. M., & Boaventura, B. C. B. (2022) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2021-0806 · Cited by 61 · see citing works
Dietary Protein Sources and Muscle Mass over the Life Course: The Lifelines Cohort Study
Alexandrov, N. V., Eelderink, C., Singh-Povel, C. M., Navis, G. J., Bakker, S. J. L., & Corpeleijn, E. (2018) · Nutrients · doi:10.3390/nu10101471 · Cited by 56 · see citing works
No Significant Differences in Muscle Growth and Strength Development When Consuming Soy and Whey Protein Supplements Matched for Leucine Following a 12 Week Resistance Training Program in Men and Women: A Randomized Trial
Lynch, H. M., Buman, M. P., Dickinson, J. M., Ransdell, L. B., Johnston, C. S., & Wharton, C. M. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17113871 · Cited by 56 · see citing works
Achieving Optimal Post-Exercise Muscle Protein Remodeling in Physically Active Adults through Whole Food Consumption
Van Vliet, S., Beals, J. W., Martinez, I. G., Skinner, S. K., & Burd, N. A. (2018) · Nutrients · doi:10.3390/nu10020224 · Cited by 56 · see citing works
Self-citation
Exploring Health-Promoting Attributes of Plant Proteins as a Functional Ingredient for the Food Sector: A Systematic Review of Human Interventional Studies
Lonnie, M., Laurie, I., Myers, M., Horgan, G., Russell, W., & Johnstone, A. (2020) · Nutrients · doi:10.3390/nu12082291 · Cited by 53 · see citing works
Soluble Whey Protein Hydrolysate Ameliorates Muscle Atrophy Induced by Immobilization via Regulating the PI3K/Akt Pathway in C57BL/6 Mice
Shin, J. E., Park, S. J., Ahn, S. I., & Choung, S.-Y. (2020) · Nutrients · doi:10.3390/nu12113362 · Cited by 52 · see citing works
Myofibrillar and mitochondrial protein synthesis rates do not differ in young men following the ingestion of carbohydrate with whey, soy, or leucine-enriched soy protein after concurrent resistance-and endurance-type exercise
Churchward-Venne, T. A., Pinckaers, P. J. M., Smeets, J. S. J., Peeters, W. M., Zorenc, A. H., Schierbeek, H., Rollo, I., Verdijk, L. B., & van Loon, L. J. C. (2019) · The Journal of Nutrition · doi:10.1093/jn/nxy251 · Cited by 51 · see citing works
Self-citation
Alternative dietary protein sources to support healthy and active skeletal muscle aging
van der Heijden, I., Monteyne, A. J., Stephens, F. B., & Wall, B. T. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuac049 · Cited by 45 · see citing works
The role of protein hydrolysates for exercise-induced skeletal muscle recovery and adaptation: a current perspective
Morgan, P. T., & Breen, L. (2021) · Nutrition & Metabolism · doi:10.1186/s12986-021-00574-z · Cited by 44 · see citing works
Amount Rather than Animal vs Plant Protein Intake Is Associated with Skeletal Muscle Mass in Community-Dwelling Middle-Aged and Older Chinese Adults: Results from the Guangzhou Nutrition and Health Study
Li, C.-Y., Fang, A.-P., Ma, W.-J., Wu, S.-L., Li, C.-L., Chen, Y.-M., & Zhu, H.-L. (2019) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2019.03.010 · Cited by 44 · see citing works
Nutritional Considerations for the Vegan Athlete
West, S., Monteyne, A. J., van der Heijden, I., Stephens, F. B., & Wall, B. T. (2023) · Advances in Nutrition · doi:10.1016/j.advnut.2023.04.012 · Cited by 42 · see citing works
Potato Protein Isolate Stimulates Muscle Protein Synthesis at Rest and with Resistance Exercise in Young Women
Oikawa, S. Y., Bahniwal, R., Holloway, T. M., Lim, C., McLeod, J. C., McGlory, C., Baker, S. K., & Phillips, S. M. (2020) · Nutrients · doi:10.3390/nu12051235 · Cited by 41 · see citing works
Dietary Protein and Muscle in Aging People: The Potential Role of the Gut Microbiome
Ni Lochlainn, M., Bowyer, R. C. E., & Steves, C. J. (2018) · doi:10.20944/preprints201806.0152.v1 · Cited by 138 · see citing works
Protein source influences acute appetite and satiety but not subsequent food intake in healthy adults
Braden, M. L., Gwin, J. A., & Leidy, H. J. (2023) · The Journal of Nutrition · doi:10.1016/j.tjnut.2023.04.001 · Cited by 25 · see citing works
Protein Requirements of Pre-Menopausal Female Athletes: Systematic Literature Review
Mercer, D., Convit, L., Condo, D., Carr, A. J., Hamilton, D. L., Slater, G., & Snipe, R. M. J. (2020) · Nutrients · doi:10.3390/nu12113527 · Cited by 20 · see citing works
Novel essential amino acid supplements enriched with L-leucine facilitate increased protein and energy intakes in older women: a randomised controlled trial
Ispoglou, T., Deighton, K., King, R. F., White, H., & Lees, M. (2017) · Nutrition Journal · doi:10.1186/s12937-017-0298-6 · Cited by 21 · see citing works
Sarcopenic obesity, pathogenesis, and treatment with a focus on exercise and protein intake
Karaağaç, Y. (2023) · Journal of Mind and Medical Sciences · doi:10.22543/2392-7674.1419 · Cited by 5 · see citing works

Authors: van Vliet, S., Burd, N. A., & van Loon, L. J.
Affiliations: University of Illinois Urbana-Champaign (US)
ORCID: Burd, Nicholas A
Venue: The Journal of Nutrition
Publisher: Elsevier BV
Published: 2015-09
Volume: 145
Issue: 9
Pages: 1981-1991
ISSN: 0022-3166 (ISSN-L)
DOI: 10.3945/jn.114.204305
OpenAlex: W2113689811
Cited by: 651
References: 100
Citations by year: 2026: 66 · 2025: 73 · 2024: 69 · 2023: 77 · 2022: 76 · 2021: 75 · 2020: 74 · 2019: 45 · 2018: 39 · 2017: 29 · 2016: 24 · 2015: 3
FWCI: 3.17
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 2711 d)
Locations: Journal of Nutrition (publishedVersion)
PubMed (publishedVersion)
Research Bank (Australian Catholic University) (submittedVersion)
Research Publications (Maastricht University) (submittedVersion, other-oa)
VUBIR (Vrije Universiteit Brussel) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
Keywords: plant proteins, animal protein, skeletal muscle anabolism, muscle protein synthesis, soy protein, wheat proteins, leucine, essential amino acids, urea synthesis, protein digestibility, muscle mass preservation, protein fortification, amino acid composition
MeSH terms: Whey Proteins, Animals, Cattle, Dietary Proteins, Humans, Leucine, Meat, Milk Proteins, Muscle Proteins, Plant Proteins, Protein Biosynthesis, Muscle, Skeletal, Postprandial Period, Soybean Proteins, Food Quality

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Skeletal Muscle Anabolic Response to Plant- versus Animal-Based Protein Consumption

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks