The DOI matches its Crossref record; 58 of the 60 references it cites were found in a registry or an index.
Biomechanics of the Sensor-Tissue Interface—Effects of Motion, Pressure, and Design on Sensor Performance and Foreign Body Response—Part II: Examples and Application
Open accessAbstract
This article is the second part of a two-part review in which we explore the biomechanics of the sensor-tissue interface as an important aspect of continuous glucose sensor biocompatibility. Part I, featured in this issue of Journal of Diabetes Science and Technology, describes a theoretical framework of how biomechanical factors such as motion and pressure (typically micromotion and micropressure) affect tissue physiology around a sensor and in turn, impact sensor performance. Here in Part II, a literature review is presented that summarizes examples of motion or pressure affecting sensor performance. Data are presented that show how both acute and chronic forces can impact continuous glucose monitor signals. Also presented are potential strategies for countering the ill effects of motion and pressure on glucose sensors. Improved engineering and optimized chemical biocompatibility have advanced sensor design and function, but we believe that mechanical biocompatibility, a rarely considered factor, must also be optimized in order to achieve an accurate, long-term, implantable sensor.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Such behavior was attributed in part to blood occlusion due to pressures applied to tissue adjacent to the sensor.86–87”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [87]
Citations
Cites
Biological Responses to Materials
Anderson, J. M. (2001) · Annual Review of Materials Research · doi:10.1146/annurev.matsci.31.1.81 · Cited by 1,465
A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses
Weinbaum, S., Cowin, S. C., & Zeng, Y. (1994) · Journal of Biomechanics · doi:10.1016/0021-9290(94)90010-8 · Cited by 1,266
Huiskes, R., Weinans, H., & van Rietbergen, B. (1992) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199201000-00014 · Cited by 1,227
Mechanical properties and Young's modulus of human skin in vivo
Agache, P. G., Monneur, C., Lévêque, J., & de Rigal, J. (1980) · Archives of Dermatological Research · doi:10.1007/bf00406415 · Cited by 742
Biophysical stimuli on cells during tissue differentiation at implant interfaces
Prendergast, P. J., Huiskes, R., & Søballé, K. (1997) · Journal of Biomechanics · doi:10.1016/s0021-9290(96)00140-6 · Cited by 637
Neovascularization of synthetic membranes directed by membrane microarchitecture
Brauker, J. H., Carr‐Brendel, V. E., Martinson, L. A., Crudele, J., Johnston, W. D., & Johnson, R. C. (1995) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820291208 · Cited by 517
Søballé, K., Hansen, E. S., Brockstedt-Rasmussen, H., Jørgensen, P. H., & Bünger, C. (1992) · Journal of Orthopaedic Research® · doi:10.1002/jor.1100100216 · Cited by 506
The Healing of Rat Skin Wounds
Levenson, S. Μ., Geever, E. F., CHOWLEY, L. V., OATES, J. F., Berard, C. W., & ROSEN, H. (1965) · Annals of Surgery · doi:10.1097/00000658-196502000-00019 · Cited by 478
Handbook of non-invasive methods and the skin
Guy, R. H. (1996) · Journal of Controlled Release · doi:10.1016/0168-3659(96)01365-x · Cited by 414
Emerging synergy between nanotechnology and implantable biosensors: A review
Vaddiraju, S., Tomazos, I., Burgess, D. J., Jain, F., & Papadimitrakopoulos, F. (2009) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2009.12.001 · Cited by 383
Research works printed but not linked: 7
- Breton MD, 2011, Diabetes Technol Ther., 13, 176
- Renard EM, Farret A, Place J, Cobelli C, Kovatchev BP, Breton MD. Closed-loop insulin delivery using subcutaneous infusion and glucose sensing, and equipped with a dedicated safety supervision algorithm, improves safety of glucose control in type 1 diabetes. Proceedings of the 46th Annual Meeting of the European Association for the Study of Diabetes; 2010 Sep 20–24; Stockholm, Sweden.
- Von Recum A, 1990, New aspects of biocompatibility: Motion at the interface
- 10.1046/j.1467-2494.2000.00037.x · DOI · Paper page
- Wu JZ, 2006, Biomedical Mater Eng., 16, 53
- Marshall AJ, 2004, Polym Prepr., 45, 100
- 10.2337/diacare.23.2.208 · DOI · Paper page
Cited by
Sorted by citations
Continuous glucose monitoring and metrics for clinical trials: an international consensus statement
Battelino, T., Alexander, C. M., Amiel, S. A., Arreaza-Rubin, G., Beck, R. W., Bergenstal, R. M., Buckingham, B. A., Carroll, J., Ceriello, A., Chow, E., et al. (2023) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(22)00319-9 · Cited by 831
Biocompatible Materials for Continuous Glucose Monitoring Devices
Nichols, S. P., Koh, A., Storm, W. L., Shin, J. H., & Schoenfisch, M. H. (2013) · Chemical Reviews · doi:10.1021/cr300387j · Cited by 347
Advanced strategies to thwart foreign body response to implantable devices
Capuani, S., Malgir, G., Chua, C. Y. X., & Grattoni, A. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10300 · Cited by 204
Challenges and recent progress in the development of a closed-loop artificial pancreas
Bequette, B. W. (2012) · Annual Reviews in Control · doi:10.1016/j.arcontrol.2012.09.007 · Cited by 184
Heinemann, L., Schoemaker, M., Schmelzeisen-Redecker, G., Hinzmann, R., Kassab, A., Freckmann, G., Reiterer, F., & Del Re, L. (2020) · Journal of Diabetes Science and Technology · doi:10.1177/1932296819855670 · Cited by 170
Metadata
- Authors
- Helton, K. L., Ratner, B. D., & Wisniewski, N. A.
- Affiliations
- University of Washington (US)
- Profusa (United States) (US)
- Corresponding author
- Wisniewski, Natalie A.
- ORCID
- Ratner, Buddy D.
- Venue
- Journal of Diabetes Science and Technology
- Publisher
- SAGE Publications
- Published
- 2011-05
- Volume
- 5
- Issue
- 3
- Pages
- 647-656
- ISSN
- 1932-2968 (ISSN-L)
- PMC
- PMC3192630
- OpenAlex
- W2092619316
- Cited by
- 102
- References
- 60
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 1 · 2023: 7 · 2022: 7 · 2021: 8 · 2020: 7 · 2019: 8 · 2018: 7 · 2017: 11 · 2016: 10 · 2015: 8 · 2014: 8 · 2013: 8 · 2012: 4
- Type
- conference abstract
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Diabetes Science and Technology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Physical Sciences › Chemistry › Analytical Chemistry › Electrochemical sensors and biosensors
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Keywords
- continuous glucose monitoring, micromotion, foreign body reaction, implantable glucose sensor, sensor design
- MeSH terms
- Animals, Biocompatible Materials, Biomechanical Phenomena, Blood Glucose, Diabetes Mellitus, Dogs, Equipment Design, Glucose, Humans, Motion, Pressure, Self Care, Swine, Blood Glucose Self-Monitoring, Reproducibility of Results, Porosity, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
