Biomimetic 3D tissue models for advanced high-throughput drug screening

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., & Yamanaka, S. (2007) · Cell · doi:10.1016/j.cell.2007.11.019 · Cited by 20,221 · see citing works

Reconstituting organ-level lung functions on a chip

Huh, D., Matthews, B. D., Mammoto, A., Montoya-Zavala, M., Hsin, H. Y., & Ingber, D. E. (2010) · Science · doi:10.1126/science.1188302 · Cited by 4,250 · see citing works

Vascular endothelial growth factor (VEGF) and its receptors

Neufeld, G., Cohen, T., Gengrinovitch, S., & Gluzman‐Poltorak, Z. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.1.9 · Cited by 3,488 · see citing works

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

Chong, J. J. H., Yang, X., Don, C. W., Minami, E., Liu, Y.-W., Weyers, J. J., Mahoney, W. M., Biber, B. P. V., Cook, S. M., Palpant, N. J., et al. (2014) · Nature · doi:10.1038/nature13233 · Cited by 1,404 · see citing works

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

Lee, K., Silva, E. A., & Mooney, D. J. (2010) · Journal of The Royal Society Interface · doi:10.1098/rsif.2010.0223 · Cited by 1,393 · see citing works

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

Yang, L., Soonpaa, M. H., Adler, E. D., Roepke, T. K., Kattman, S. J., Kennedy, M., Henckaerts, E., Bonham, K., Abbott, G. W., Linden, R. M., et al. (2008) · Nature · doi:10.1038/nature06894 · Cited by 1,389 · see citing works

Tissue-Engineered Lungs for in Vivo Implantation

Petersen, T. H., Calle, E. A., Zhao, L., Lee, E. J., Gui, L., Raredon, M. S. B., Gavrilov, K., Yi, T., Zhuang, Z. W., Breuer, C. K., et al. (2010) · Science · doi:10.1126/science.1189345 · Cited by 1,177 · see citing works

Global Burden of Disease

Mathers, C. D. (2008) · Elsevier eBooks · doi:10.1016/b978-012373960-5.00335-x · Cited by 1,125 · see citing works

Tissue Engineering of a Differentiated Cardiac Muscle Construct

Zimmermann, W.-H., Schneiderbanger, K., Schubert, P., Didié, M., Münzel, F., Heubach, J. F., Kostin, S., Neuhuber, W. L., & Eschenhagen, T. (2002) · Circulation Research · doi:10.1161/hh0202.103644 · Cited by 917 · see citing works

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

Jang, K., Mehr, A. P., Hamilton, G. A., McPartlin, L. A., Chung, S., Suh, K. Y., & Ingber, D. E. (2013) · Integrative Biology · doi:10.1039/c3ib40049b · Cited by 850 · see citing works

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

Wang, G., McCain, M. L., Yang, L., He, A., Pasqualini, F. S., Agarwal, A., Yuan, H., Jiang, D., Zhang, D., Zangi, L., et al. (2014) · Nature Medicine · doi:10.1038/nm.3545 · Cited by 837 · see citing works

Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration

Metcalfe, A. D., & Ferguson, M. W. J. (2006) · Journal of The Royal Society Interface · doi:10.1098/rsif.2006.0179 · Cited by 786 · see citing works

Tissue Engineering and Regenerative Medicine: History, Progress, and Challenges

Berthiaume, F., Maguire, T. J., & Yarmush, M. L. (2011) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-061010-114257 · Cited by 734 · see citing works

Vascular endothelial growth factor and its receptors

Klagsbrun, M., & D'Amore, P. A. (1996) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(96)00027-5 · Cited by 682 · see citing works

Microengineered physiological biomimicry: Organs-on-Chips

Huh, D., Torisawa, Y., Hamilton, G. A., Kim, H. J., & Ingber, D. E. (2012) · Lab on a Chip · doi:10.1039/c2lc40089h · Cited by 667 · see citing works

Bone Morphogenetic Proteins Stimulate Angiogenesis through Osteoblast-Derived Vascular Endothelial Growth Factor A

Deckers, M. M. L., van Bezooijen, R. L., van der Horst, G., Hoogendam, J., van der Bent, C., Papapoulos, S. E., & Löwik, C. W. G. M. (2002) · Endocrinology · doi:10.1210/endo.143.4.8719 · Cited by 651 · see citing works

Electrospun fine-textured scaffolds for heart tissue constructs

Zong, X., Bien, H., Chung, C.-Y., Yin, L., Fang, D., Hsiao, B. S., Chu, B., & Entcheva, E. G. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.01.052 · Cited by 643 · see citing works

Skin tissue engineering — In vivo and in vitro applications

Groeber, F., Holeiter, M., Hampel, M., Hinderer, S., & Schenke‐Layland, K. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.01.005 · Cited by 633 · see citing works

Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs

Kim, D.-H., Lipke, E. A., Kim, P., Cheong, R., Thompson, S., Delannoy, M., Suh, K.-Y., Tung, L., & Levchenko, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906504107 · Cited by 611 · see citing works

Matrix nanotopography as a regulator of cell function

Kim, D., Provenzano, P. P., Smith, C. L., & Levchenko, A. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201108062 · Cited by 576 · see citing works

Engineered skin substitutes: practices and potentials

Supp, D. M., & Boyce, S. T. (2005) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2004.07.023 · Cited by 519 · see citing works

Development of a drug screening platform based on engineered heart tissue

Hansen, A., Eder, A., Bönstrup, M., Flato, M., Mewe, M., Schaaf, S., Aksehirlioglu, B., Schwörer, A., Uebeler, J., & Eschenhagen, T. (2010) · Circulation Research · doi:10.1161/circresaha.109.211458 · Cited by 510 · see citing works

Mechanical stimulation improves tissue-engineered human skeletal muscle

Powell, C., Smiley, B. L., Mills, J., & Vandenburgh, H. H. (2002) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00595.2001 · Cited by 497 · see citing works

Microfluidic heart on a chip for higher throughput pharmacological studies

Agarwal, A., Goss, J. A., Cho, A., McCain, M. L., & Parker, K. K. (2013) · Lab on a Chip · doi:10.1039/c3lc50350j · Cited by 495 · see citing works

Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels

Tsang, V. L., Chen, A. A., Cho, L. M., Jadin, K. D., Sah, R. L., DeLong, S., West, J. L., & Bhatia, S. N. (2007) · The FASEB Journal · doi:10.1096/fj.06-7117com · Cited by 462 · see citing works

Perfused multiwell plate for 3D liver tissue engineering

Domanský, K., Inman, W., Serdy, J., Dash, A., Lim, M. H. M., & Griffith, L. G. (2009) · Lab on a Chip · doi:10.1039/b913221j · Cited by 446 · see citing works

A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity

Astashkina, A. I., Mann, B. K., & Grainger, D. W. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.01.001 · Cited by 432 · see citing works

Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues

Legant, W. R., Pathak, A., Yang, M. T., Deshpande, V. S., McMeeking, R. M., & Chen, C. S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900174106 · Cited by 427 · see citing works

Cardiac Tissue Engineering

Hirt, M. N., Hansen, A., & Thomas Eschenhagen, A. (2014) · Circulation Research · doi:10.1161/circresaha.114.300522 · Cited by 426 · see citing works

A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues

Boudou, T., Legant, W. R., Mu, A., Borochin, M. A., Thavandiran, N., Radisic, M., Zandstra, P. W., Epstein, J. A., Margulies, K. B., & Chen, C. S. (2012) · Tissue Engineering Part A · doi:10.1089/ten.tea.2011.0341 · Cited by 413 · see citing works

Microengineered Platforms for Cell Mechanobiology

Kim, D., Wong, P. K., Park, J., Levchenko, A., & Sun, Y. (2009) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-061008-124915 · Cited by 407 · see citing works

Functional tissue engineering for tendon repair: A multidisciplinary strategy using mesenchymal stem cells, bioscaffolds, and mechanical stimulation

Butler, D. L., Juncosa‐Melvin, N., Boivin, G. P., Galloway, M. T., Shearn, J. T., Gooch, C., & Awad, H. A. (2007) · Journal of Orthopaedic Research® · doi:10.1002/jor.20456 · Cited by 378 · see citing works

Repopulation of decellularized mouse heart with human induced pluripotent stem cell-derived cardiovascular progenitor cells

Lu, T., Lin, B., Kim, J. K., Sullivan, M. L. G., Tobita, K., Salama, G., & Yang, L. (2013) · Nature Communications · doi:10.1038/ncomms3307 · Cited by 370 · see citing works

Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies

Bursac, N., Papadaki, M., Cohen, R. J., Schöen, F. J., Eisenberg, S. R., Carrier, R. L., Vunjak‐Novakovic, G., & Freed, L. E. (1999) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1999.277.2.h433 · Cited by 366 · see citing works

Decellularization methods of porcine kidneys for whole organ engineering using a high-throughput system

Sullivan, D. C., Mirmalek-Sani, S.-H., Deegan, D. B., Baptista, P. M., Aboushwareb, T., Atala, A., & Yoo, J. J. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.07.023 · Cited by 363 · see citing works

Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation

Hirt, M. N., Boeddinghaus, J., Mitchell, A. N., Schaaf, S., Börnchen, C., Müller, C., Schulz, H., Hübner, N., Stenzig, J., Stoehr, A., et al. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.05.009 · Cited by 355 · see citing works

Effect of precise mechanical loading on fibroblast populated collagen lattices: Morphological changes

Eastwood, M., Mudera, V., McGrouther, D. A., & Brown, R. (1998) · Cell Motility and the Cytoskeleton · doi:10.1002/(sici)1097-0169(1998)40:1 · Cited by 337 · see citing works

Direct differentiation of human embryonic stem cells into selective neurons on nanoscale ridge/groove pattern arrays

Lee, M. R., Kwon, K. W., Jung, H., Kim, H. N., Suh, K. Y., Kim, K., & Kim, K.-S. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.02.012 · Cited by 333 · see citing works

Drug‐screening platform based on the contractility of tissue‐engineered muscle

Vandenburgh, H. H., Shansky, J., Benesch, F., Barbata, V., Reid, J., Thorrez, L., Valentini, R. F., & Crawford, G. (2008) · Muscle & Nerve · doi:10.1002/mus.20931 · Cited by 323 · see citing works

Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model

Sung, J. H., Yu, J., Luo, D., Shuler, M. L., & March, J. C. (2010) · Lab on a Chip · doi:10.1039/c0lc00273a · Cited by 321 · see citing works

Improved Human Embryonic Stem Cell Embryoid Body Homogeneity and Cardiomyocyte Differentiation from a Novel V-96 Plate Aggregation System Highlights Interline Variability

Burridge, P. W., Anderson, D., Priddle, H., Muñoz, M. D. B., Chamberlain, S. R., Allegrucci, C., Young, L. E., & Denning, C. N. (2006) · Stem Cells · doi:10.1634/stemcells.2006-0598 · Cited by 301 · see citing works

Bone tissue engineering bioreactors: Dynamic culture and the influence of shear stress

Yeatts, A. B., & Fisher, J. P. (2010) · Bone · doi:10.1016/j.bone.2010.09.138 · Cited by 298 · see citing works

Engineering Myocardial Tissue

Thomas Eschenhagen, A., & Zimmermann, W. H. (2005) · Circulation Research · doi:10.1161/01.res.0000196562.73231.7d · Cited by 261 · see citing works

Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo

Juhas, M., Engelmayr, G. C., Fontanella, A. N., Palmer, G. M., & Bursac, N. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402723111 · Cited by 246 · see citing works

Building a Tiered Approach to In Vitro Predictive Toxicity Screening: A Focus on Assays with In Vivo Relevance

McKim, J. M. (2010) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/138620710790596736 · Cited by 231 · see citing works

Scaffold-Free Three-Dimensional Cell Culture Utilizing Micromolded Nonadhesive Hydrogels

Napolitano, A. P., Dean, D. M., Man, A. J., Youssef, J., Ho, D. N., Rago, A. P., Lech, M. P., & Morgan, J. R. (2007) · BioTechniques · doi:10.2144/000112591 · Cited by 231 · see citing works

Tissue geometry patterns epithelial–mesenchymal transition via intercellular mechanotransduction

Gomez, E. W., Chen, Q. K., Gjorevski, N., & Nelson, C. M. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22545 · Cited by 214 · see citing works

Three-dimensional neuron–muscle constructs with neuromuscular junctions

Morimoto, Y., Kato‐Negishi, M., Onoe, H., & Takeuchi, S. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.08.062 · Cited by 196 · see citing works

Controlled Release of Stromal Cell–Derived Factor-1alpha In Situ Increases C-kit + Cell Homing to the Infarcted Heart

Zhang, G., Nakamura, Y., Wang, X., Hu, Q., Suggs, L. J., & Zhang, J. J. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0013 · Cited by 184 · see citing works

Incorporation of 3T3‐L1 Cells To Mimic Bioaccumulation in a Microscale Cell Culture Analog Device for Toxicity Studies

Viravaidya‐Pasuwat, K., & Shuler, M. L. (2004) · Biotechnology Progress · doi:10.1021/bp034238d · Cited by 184 · see citing works

Mechanical Strain-Stimulated Remodeling of Tissue-Engineered Blood Vessel Constructs

Seliktar, D., Nerem, R. M., & Galis, Z. S. (2003) · Tissue Engineering · doi:10.1089/107632703768247359 · Cited by 179 · see citing works

Advanced maturation by electrical stimulation: Differences in response between C2C12 and primary muscle progenitor cells

Langelaan, M. L. P., Boonen, K. J. M., Rosaria-Chak, K. Y., van der Schaft, D. W. J., Post, M. J., & Baaijens, F. F. (2010) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.345 · Cited by 175 · see citing works

‘Human-on-a-chip’ Developments: A Translational Cutting-edge Alternative to Systemic Safety Assessment and Efficiency Evaluation of Substances in Laboratory Animals and Man?

Marx, U., Walles, H., Hoffmann, S., Lindner, G., Horland, R., Sonntag, F., Klotzbach, U., Sakharov, D. A., Tonevitsky, A., & Lauster, R. (2012) · Alternatives to Laboratory Animals · doi:10.1177/026119291204000504 · Cited by 174 · see citing works

Tissue-Engineered Lung: An In Vivo and In Vitro Comparison of Polyglycolic Acid and Pluronic F-127 Hydrogel/Somatic Lung Progenitor Cell Constructs to Support Tissue Growth

Cortiella, J., Nichols, J. E., Kojima, K., Bonassar, L. J., Dargon, P. T., Roy, A. K., Vacant, M. P., Niles, J. A., & Vacanti, C. A. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.1213 · Cited by 172 · see citing works

Tissue Engineered Human Skin Equivalents

Zhang, Z., & Michniak‐Kohn, B. B. (2012) · Pharmaceutics · doi:10.3390/pharmaceutics4010026 · Cited by 171 · see citing works

Cardiac Organogenesis in Vitro : Reestablishment of Three-Dimensional Tissue Architecture by Dissociated Neonatal Rat Ventricular Cells

Akins, R. E., Boyce, R., Madonna, M. L., Schroedl, N. A., Gonda, S. R., McLaughlin, T., & Hartzell, C. R. (1999) · Tissue Engineering · doi:10.1089/ten.1999.5.103 · Cited by 171 · see citing works

Patterning Methods for Polymers in Cell and Tissue Engineering

Kim, H. N., Kang, D.-H., Kim, M. S., Jiao, A., Kim, D., & Suh, K. Y. (2012) · Annals of Biomedical Engineering · doi:10.1007/s10439-012-0510-y · Cited by 165 · see citing works

p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation

Stanton, L., Sabari, S., Sampaio, A. V., Underhill, T. M., & Beier, F. (2004) · Biochemical Journal · doi:10.1042/bj20030874 · Cited by 161 · see citing works

Biomimetic Nanopatterns as Enabling Tools for Analysis and Control of Live Cells

Kim, D., Lee, H., Lee, Y. K., Nam, J., & Levchenko, A. (2010) · Advanced Materials · doi:10.1002/adma.201000468 · Cited by 161 · see citing works

Epidermal Nerve Fibers Modulate Keratinocyte Growth via Neuropeptide Signaling in an Innervated Skin Model

Roggenkamp, D., Köpnick, S., Stäb, F., Wenck, H., Schmelz, M., & Neufang, G. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.464 · Cited by 160 · see citing works

Human hepatocyte transplantation: state of the art

Fitzpatrick, E., Mitry, R. R., & Dhawan, A. K. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02152.x · Cited by 154 · see citing works

Derivation of Distal Airway Epithelium from Human Embryonic Stem Cells

Samadikuchaksaraei, A., Cohen, S., Isaac, K., Rippon, H. J., Polak, J. M., Bielby, R. C., & Bishop, A. E. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.867 · Cited by 149 · see citing works

Structure and Functional Evaluation of Tendon–Skeletal Muscle Constructs Engineered in Vitro

Larkin, L. M., Calve, S., Kostrominova, T. Y., & Arruda, E. M. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.3149 · Cited by 137 · see citing works

A tissue-engineered endothelialized dermis to study the modulation of angiogenic and angiostatic molecules on capillary-like tube formation in vitro

Hudon, V., Berthod, F., Black, A. F., Damour, O., Germain, L., & Auger, F. A. (2003) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2003.05298.x · Cited by 136 · see citing works

A home away from home: Challenges and opportunities in engineering in vitro muscle satellite cell niches

Cosgrove, B. D., Sacco, A., Gilbert, P. M., & Blau, H. M. (2009) · Differentiation · doi:10.1016/j.diff.2009.08.004 · Cited by 135 · see citing works

Identification of a bone marrow–derived epithelial-like population capable of repopulating injured mouse airway epithelium

Wong, A. P., Keating, A., Lu, W.-Y., Duchesneau, P., Wang, X., Sacher, A. G., Hu, J., & Waddell, T. K. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36882 · Cited by 130 · see citing works

Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity

DesRochers, T. M., Suter, L., Roth, A., & Kaplan, D. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059219 · Cited by 128 · see citing works

Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration

Kim, D., Gupta, K., Smith, R. R., Kim, P., Ahn, E. H., Kim, H. N., Marbán, E., Suh, K. Y., & Levchenko, A. (2012) · Integrative Biology · doi:10.1039/c2ib20067h · Cited by 124 · see citing works

The role of skin substitutes in the treatment of burn injuries

Shakespeare, P. G. (2005) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2004.07.015 · Cited by 114 · see citing works

A 3-D organoid kidney culture model engineered for high-throughput nephrotoxicity assays

Astashkina, A. I., Mann, B. K., Prestwich, G. D., & Grainger, D. W. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.02.063 · Cited by 114 · see citing works

Growth, differentiation, transplantation and survival of human skeletal myofibers on biodegradable scaffolds

Thorrez, L., Shansky, J., Wang, L., Fast, L. D., VandenDriessche, T., Chuah, M., Mooney, D. J., & Vandenburgh, H. H. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.09.014 · Cited by 108 · see citing works

High-Content Drug Screening with Engineered Musculoskeletal Tissues

Vandenburgh, H. H. (2009) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2009.0445 · Cited by 103 · see citing works

Human Embryonic Stem Cells Differentiated to Lung Lineage-Specific Cells Ameliorate Pulmonary Fibrosis in a Xenograft Transplant Mouse Model

Banerjee, E. R., Laflamme, M. A., Papayannopoulou, T., Kahn, M., Murry, C. E., & Henderson, W. R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033165 · Cited by 100 · see citing works

Effects of Solar Ultraviolet Radiation on Engineered Human Skin Equivalent Containing Both Langerhans Cells and Dermal Dendritic Cells

Béchetoille, N., Dezutter‐Dambuyant, C., Damour, O., André, V., Orly, I., & Perrier, É. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0405 · Cited by 100 · see citing works

A high-throughput three-dimensional cell migration assay for toxicity screening with mobile device-based macroscopic image analysis

Timm, D. M., Chen, J., Sing, D. C., Gage, J. A., Haisler, W. L., Neeley, S. K., Raphael, R. M., Dehghani, M., Rosenblatt, K. P., Killian, T. C., et al. (2013) · Scientific Reports · doi:10.1038/srep03000 · Cited by 93 · see citing works

Shear‐stress preconditioning and tissue‐engineering‐based paradigms for generating arterial substitutes

Baguneid, M. S., Murray, D., Salacinski, H. J., Fuller, B. J., Hamilton, G., Walker, M. G., & Seifalian, A. M. (2004) · Biotechnology and Applied Biochemistry · doi:10.1042/ba20030148 · Cited by 93 · see citing works

Functional Neuromuscular Junctions Formed by Embryonic Stem Cell-Derived Motor Neurons

Umbach, J. A., Adams, K. L., Gundersen, C. B., & Novitch, B. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036049 · Cited by 90 · see citing works

Fabrication of poly(ethylene glycol): gelatin methacrylate composite nanostructures with tunable stiffness and degradation for vascular tissue engineering

Kim, P., Yuan, A. E., Nam, K., Jiao, A., & Kim, D. (2014) · Biofabrication · doi:10.1088/1758-5082/6/2/024112 · Cited by 87 · see citing works

Engineering of a Complex Organ: Progress Toward Development of a Tissue-engineered Lung

Nichols, J. E., & Cortiella, J. (2008) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200802-022aw · Cited by 86 · see citing works

Robust T-tubulation and maturation of cardiomyocytes using tissue-engineered epicardial mimetics

Bian, W., Badie, N., Himel, H. D., & Bursac, N. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.01.045 · Cited by 82 · see citing works

Factors affecting the structure and maturation of human tissue engineered skeletal muscle

Martin, N. R. W., Passey, S. L., Player, D. J., Khodabukus, A., Ferguson, R. A., Sharples, A. P., Mudera, V., Baar, K., & Lewis, M. P. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.04.002 · Cited by 81 · see citing works

Thermoresponsive Nanofabricated Substratum for the Engineering of Three-Dimensional Tissues with Layer-by-Layer Architectural Control

Jiao, A., Trosper, N. E., Yang, H. S., Kim, J., Tsui, J. H., Frankel, S., Murry, C. E., & Kim, D. (2014) · ACS Nano · doi:10.1021/nn4063962 · Cited by 79 · see citing works

Cardiac-like flow generator for long-term imaging of endothelial cell responses to circulatory pulsatile flow at microscale

Chen, H., Cornwell, J. A., Zhang, H., Lim, T., Resurreccion, R., Port, T., Rosengarten, G., & Nordon, R. E. (2013) · Lab on a Chip · doi:10.1039/c3lc50123j · Cited by 78 · see citing works

Regulating Fibrinolysis to Engineer Skeletal Muscle from the C2C12 Cell Line

Khodabukus, A., & Baar, K. (2009) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2008.0286 · Cited by 77 · see citing works

Gastrointestinal tract modelling in health and disease

Liao, D., Zhao, J., & Gregersen, H. N. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.169 · Cited by 67 · see citing works

High Throughput Screening of Transdermal Formulations

Karande, P., & Mitragotri, S. (2002) · Pharmaceutical Research · doi:10.1023/a:1015362230726 · Cited by 66 · see citing works

A biodegradable microvessel scaffold as a framework to enable vascular support of engineered tissues

Ye, X., Lu, L., Kolewe, M. E., Park, H., Larson, B. L., Kim, E. S., & Freed, L. E. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.09.039 · Cited by 64 · see citing works

Tissue-engineered skin substitutes in regenerative medicine

Mansbridge, J. N. (2009) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2009.08.008 · Cited by 64 · see citing works

Transfer of Melanosomes in a Skin Equivalent Model In Vitro

Topol, B. M., Haimes, H. B., Dubertret, L., & Bell, E. (1986) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12456314 · Cited by 61 · see citing works

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Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies

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3D Bioprinting in Tissue Engineering for Medical Applications: The Classic and the Hybrid

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Engineering biofunctional in vitro vessel models using a multilayer bioprinting technique

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In Vitro Microfluidic Models for Neurodegenerative Disorders

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Thermally-triggered fabrication of cell sheets for tissue engineering and regenerative medicine

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Scaffold-free three-dimensional cell culturing using magnetic levitation

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A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it

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Microchannels in Development, Survival, and Vascularisation of Tissue Analogues for Regenerative Medicine

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Tissue Engineered Bands of Büngner for Accelerated Motor and Sensory Axonal Outgrowth

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A high-throughput in vitro ring assay for vasoactivity using magnetic 3D bioprinting

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In Vitro Model of the Epidermis

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Co-culture approaches for cultivated meat production

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Recent Advances in Magnetic Levitation: A Biological Approach from Diagnostics to Tissue Engineering

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In Vitro Immune Organs-on-Chip for Drug Development: A Review

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Bioengineered 3D Glial Cell Culture Systems and Applications for Neurodegeneration and Neuroinflammation

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Myocardial slices come to age: an intermediate complexity in vitro cardiac model for translational research

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Biosynthetic, biomimetic, and self-assembled vascularized Organ-on-a-Chip systems

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Advances in In Vitro Models of Neuromuscular Junction: Focusing on Organ‐on‐a‐Chip, Organoids, and Biohybrid Robotics

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Psychiatry in a Dish: Stem Cells and Brain Organoids Modeling Autism Spectrum Disorders

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Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery

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The Importance of Biophysical and Biochemical Stimuli in Dynamic Skeletal Muscle Models

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Bioprinting of novel 3D tumor array chip for drug screening

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Harvest of quality-controlled bovine myogenic cells and biomimetic bovine muscle tissue engineering for sustainable meat production

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From 3D printing to 3D bioprinting: the material properties of polymeric material and its derived bioink for achieving tissue specific architectures

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Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy

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3D Printing, Ink Casting and Micromachined Lamination (3D PICLμM): A Makerspace Approach to the Fabrication of Biological Microdevices

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Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms

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Lymph Nodes-On-Chip: Promising Immune Platforms for Pharmacological and Toxicological Applications

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Recent Developments in 3D Bio-Printing and Its Biomedical Applications

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Combined Effect of Cryogel Matrix and Temperature-Reversible Soluble–Insoluble Polymer for the Development of in Vitro Human Liver Tissue

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Elastin-like Polypeptide-Based Bioink: A Promising Alternative for 3D Bioprinting

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Considerations to Be Taken When Carrying Out Medicinal Plant Research—What We Learn from an Insight into the IC50 Values, Bioavailability and Clinical Efficacy of Exemplary Anti-Inflammatory Herbal Components

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