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Changes in thymic function with age and during the treatment of HIV infection

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Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

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The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery

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Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients

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The success of assisted reproduction technologies in relation to composition of the total regulatory T cell (Treg) pool and different Treg subsets

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Regulatory T-cell subset distribution in children with primary hypertension is associated with hypertension severity and hypertensive target organ damage

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The role of the thymus in allogeneic bone marrow transplantation and the recovery of the peripheral T-cell compartment

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Dietary Zinc Deficiency in Rodents: Effects on T-Cell Development, Maturation and Phenotypes

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EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children

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T-cell ageing in end-stage renal disease patients: Assessment and clinical relevance

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T cell markers recount the course of immunosenescence in healthy individuals and chronic kidney disease

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Primary Cytomegalovirus Infection Significantly Impacts Circulating T Cells in Kidney Transplant Recipients

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Altered CD31 expression and activity in helper T cells of acute coronary syndrome patients

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Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial

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T Cell Receptor Excision Circle (TREC) Monitoring after Allogeneic Stem Cell Transplantation; a Predictive Marker for Complications and Clinical Outcome

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Loss of CD31 receptor in CD4+ and CD8+ T-cell subsets in children with primary hypertension is associated with hypertension severity and hypertensive target organ damage

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Premature ageing of the immune system underlies immunodeficiency in ataxia telangiectasia

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The adhesion molecule PECAM-1 enhances the TGF-β–mediated inhibition of T cell function

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Cell-Associated HIV-1 Unspliced-to-Multiply-Spliced RNA Ratio at 12 Weeks of ART Predicts Immune Reconstitution on Therapy

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Excessive conversion and impaired thymic output contribute to disturbed regulatory T-cell homeostasis in AIDS patients with low CD4 cell counts

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Functional analysis of clinical response to low-dose IL-2 in patients with refractory chronic graft-versus-host disease

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Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation

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CD31 Is Required on CD4+ T Cells To Promote T Cell Survival during Salmonella Infection

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Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy

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T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death

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Maternal gut microbiota during pregnancy and the composition of immune cells in infancy

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Association of neutrophil-lymphocyte ratio and T lymphocytes with the pathogenesis and progression of HBV-associated primary liver cancer

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Multiple Sclerosis: A Disorder of Altered T-Cell Homeostasis

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Low‐affinity TCR engagement drives IL ‐2‐dependent post‐thymic maintenance of naive CD 4+ T cells in aged humans

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Thymic hyperplasia after chemotherapy in adults with mature B cell lymphoma and its influence on thymic output and CD4+T cells repopulation

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Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma

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A very low thymus function identifies patients with substantial increased risk for long-term mortality after kidney transplantation

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Developmentally determined reduction in CD31 during gestation is associated with CD8 + T cell effector differentiation in preterm infants

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Two separate effects contribute to regulatory T cell defect in systemic lupus erythematosus patients and their unaffected relatives

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End-Stage Renal Disease Causes Skewing in the TCR Vβ-Repertoire Primarily within CD8+ T Cell Subsets

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Reduced Thymic Size but No Evidence of Impaired Thymic Function in Uninfected Children Born to Human Immunodeficiency Virus-infected Mothers

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Impaired Thymic Output in Patients with Chronic Hepatitis C Virus Infection

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Age-Associated Differences in MiRNA Signatures Are Restricted to CD45RO Negative T Cells and Are Associated with Changes in the Cellular Composition, Activation and Cellular Ageing

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Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature

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Mesenchymal stromal cells improve early lymphocyte recovery and T cell reconstitution after autologous hematopoietic stem cell transplantation in patients with malignant lymphomas

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Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV

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Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant

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T-Cell Subset Distribution in HIV-1–Infected Patients After 12 Years of Treatment-Induced Viremic Suppression

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Establishment and Maintenance of the Human Naïve CD4+ T-Cell Compartment

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Reduced T-Cell Thymic Export Reflected by sj-TREC in Patients with Coronary Artery Disease

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Oral immunotherapy in hen’s egg‐allergic children increases a hypo‐proliferative subset of CD4+ T cells that could constitute a marker of tolerance achievement

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Haematopoietic Stem Cell Transplantation Results in Extensive Remodelling of the Clonal T Cell Repertoire in Multiple Sclerosis

Massey, J. C., Jackson, K., Singh, M., Hughes, B., Withers, B., Ford, C., Khoo, M., Hendrawan, K., Zaunders, J., Muylder, B. C.-D., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.798300 · Cited by 26

Pretransplant thymic function predicts acute rejection in antithymocyte globulin–treated renal transplant recipients

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Cancer‐driven changes link T cell frequency to muscle strength in people with cancer: a pilot study

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Oxidative DNA damage in reconstituting T cells is associated with relapse and inferior survival after allo-SCT

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Homeostatic signals do not drive post-thymic T cell maturation

Houston, E. G., Boursalian, T. E., & Fink, P. J. (2012) · Cellular Immunology · doi:10.1016/j.cellimm.2012.02.005 · Cited by 21

High purity and yield of natural Tregs from cord blood using a single step selection method

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End stage renal disease patients have a skewed T cell receptor Vβ repertoire

Huang, L., Langerak, A. W., Wolvers-Tettero, I. L. M., Meijers, R. W. J., Baan, C. C., Litjens, N. H. R., & Betjes, M. G. H. (2015) · Immunity & Ageing · doi:10.1186/s12979-015-0055-7 · Cited by 21

The immune system in infants: Relevance to xenotransplantation

Bikhet, M. H., Morsi, M., Hara, H., Rhodes, L. A., Carlo, W. F., Cleveland, D. C., Cooper, D. K. C., & Iwase, H. (2020) · Pediatric Transplantation · doi:10.1111/petr.13795 · Cited by 22

Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells

Newman, D. K., Fu, G., McOlash, L., Schauder, D., Newman, P. J., Cui, W., Rao, S., Johnson, B. D., Gershan, J. A., & Riese, M. J. (2018) · Journal of Leukocyte Biology · doi:10.1002/jlb.2hi0617-229rrr · Cited by 24

Interleukin-8 as a candidate for thymoma identification and recurrence surveillance

Gao, S., Jiang, J., Jin, C., Gao, J., Xiong, D., Yang, P., Cui, S., Yang, W., Leng, Q., Dong, J., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18697-x · Cited by 20

Naive T Lymphocytes and Recent Thymic Emigrants Are Associated With HIV-1 Disease History in French Adolescents and Young Adults Infected in the Perinatal Period: The ANRS-EP38-IMMIP Study

Blanche, S., Scott‐Algara, D., Chenadec, J. L., Didier, C., Montange, T., Avettand-Fènoël, V., Rouzioux, C., Mélard, A., Viard, J., Dollfus, C., et al. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit729 · Cited by 21

Recent Thymus Emigrant CD4+ T Cells Predict HIV Disease Progression in Patients With Perinatally Acquired HIV

zakhour, R. G., Tran, D. Q., Degaffe, G. H., Bell, C., Donnachie, E., Zhang, W., Pérez, N., Benjamins, L. J., Bianco, G. P. D., Rodriguez, G. H., et al. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw030 · Cited by 20

Alemtuzumab as Antirejection Therapy

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OMIP‐013: Differentiation of human T‐cells

Mahnke, Y. D., Beddall, M. H., & Roederer, M. (2012) · Cytometry Part A · doi:10.1002/cyto.a.22201 · Cited by 20

Thymic Activity and T Cell Repertoire Recovery after Autologous Hematopoietic Stem Cell Transplantation Preceded by Myeloablative Radiotherapy or Chemotherapy

Głowala‐Kosińska, M., Chwieduk, A., Smagur, A., Fidyk, W., Najda, J., Mitrus, I., & Giebel, S. (2016) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2016.01.014 · Cited by 20

Immunosenescence in aging and neurodegenerative diseases: evidence, key hallmarks, and therapeutic implications

Chen, Z., Mao, Z., Tang, W., Shi, Y., Liu, J., & You, Y. (2025) · Translational Neurodegeneration · doi:10.1186/s40035-025-00517-1 · Cited by 27

Pre-transplant Thymic Function Predicts Is Associated With Patient Death After Kidney Transplantation

Courivaud, C., Bamoulid, J., Crépin, T., Gaiffe, É., Laheurte, C., Saas, P., & Ducloux, D. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01653 · Cited by 19

The personalized application of biomaterials based on age and sexuality specific immune responses

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Recent thymic emigrants as the bridge between thymoma and autoimmune diseases

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Renewal of the T-cell compartment in multiple sclerosis patients treated with glatiramer acetate

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T Cells of Infants Are Mature, but Hyporeactive Due to Limited Ca2+ Influx

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Lymph node and circulating T cell characteristics are strongly correlated in end-stage renal disease patients, but highly differentiated T cells reside within the circulation

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Initiation of c-ART in HIV-1 Infected Patients Is Associated With a Decrease of the Metabolic Activity of the Thymus Evaluated Using FDG-PET/Computed Tomography

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Decreased thymic output predicts progression of chronic kidney disease

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Rapid T cell repopulation after rabbit anti-thymocyte globulin (rATG) treatment is driven mainly by cytomegalovirus

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