Cited by 343Gut microbiota and healthHematopoietic Stem Cell TransplantationNeutropenia and Cancer Infections

The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.

Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota

Open access

Josefsdottir, Kamilla S., Baldridge, Megan T., Kadmon, Claudine S., King, Katherine Y.·2017·Blood

DOI 10.1182/blood-2016-03-708594PMC PMC5301822

Open this paper in CoChat — free account Open PDF

Abstract

Key Points: Antibiotics cause multilineage alterations in murine hematopoiesis, with marked suppression of multipotent progenitors. Suppression of bone marrow populations results from depletion of intestinal microbiota.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1182/blood-2016-03-708594

Cites

34 of 34 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Role of the microbiota in immunity and inflammation.
Belkaid, Y., & Hand, T. W. (2014) · Cell · doi:10.1016/j.cell.2014.03.011 · Cited by 5,385
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
Wilson, A., Laurenti, E., Oser, G., van der Wath, R. C., Blanco-Bose, W., Jaworski, M., Offner, S., Dunant, C. F., Eshkind, L., Bockamp, E., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.048 · Cited by 1,908
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
Abt, M. C., Osborne, L. C., Monticelli, L. A., Doering, T. A., Alenghat, T., Sonnenberg, G. F., Paley, M. A., Antenus, M., Williams, K. L., Erikson, J., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.04.011 · Cited by 993
Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
Baldridge, M. T., King, K. Y., Boles, N. C., Weksberg, D. C., & Goodell, M. A. (2010) · Nature · doi:10.1038/nature09135 · Cited by 877
Self-citation
Neutrophil ageing is regulated by the microbiome
Zhang, D., Chen, G., Manwani, D., Mortha, A., Xu, C., Faith, J. J., Burk, R. D., Kunisaki, Y., Jang, J.-E., Scheiermann, C., et al. (2015) · Nature · doi:10.1038/nature15367 · Cited by 839
Clonal dynamics of native haematopoiesis
Sun, J., Ramos, A., Chapman, B., Johnnidis, J. B., Le, L., Ho, Y.-J., Klein, A. M., Hofmann, O., & Camargo, F. D. (2014) · Nature · doi:10.1038/nature13824 · Cited by 803
The microbiome in infectious disease and inflammation
Honda, K., & Littman, D. R. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-074937 · Cited by 791
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
Busch, K., Klapproth, K., Barile, M., Flossdorf, M., Holland-Letz, T., Schlenner, S. M., Reth, M., Höfer, T., & Rodewald, H.-R. (2015) · Nature · doi:10.1038/nature14242 · Cited by 769
Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions
Pietras, E. M., Reynaud, D., Kang, Y.-A., Carlin, D., Calero-Nieto, F. J., Leavitt, A. D., Stuart, J. M., Göttgens, B., & Passegué, E. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.05.003 · Cited by 723
Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection
Khosravi, A., Yáñez, A., Price, J. G., Chow, A. T., Mérad, M., Goodridge, H. S., & Mazmanian, S. K. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.02.006 · Cited by 668

Show all 34 references

Sorted by citations

Items 301–343 of 343

Additional file 17 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056053
Additional file 3 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056065
Additional file 6 of Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice
Dessein, R., Bauduin, M., Grandjean, T., Guern, R. L., Figeac, M., Beury, D., Faure, K., Faveeuw, C., Guery, B., Gosset, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13115148
Additional file 4 of Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice
Dessein, R., Bauduin, M., Grandjean, T., Guern, R. L., Figeac, M., Beury, D., Faure, K., Faveeuw, C., Guery, B., Gosset, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13115142
Additional file 11 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056035
Additional file 18 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056056
Additional file 8 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056080
Additional file 6 of Androgen-induced gut dysbiosis disrupts glucolipid metabolism and endocrinal functions in polycystic ovary syndrome
Han, Q., Wang, J., Li, W., Chen, Z.-J., & Du, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14551578
Additional file 3 of Androgen-induced gut dysbiosis disrupts glucolipid metabolism and endocrinal functions in polycystic ovary syndrome
Han, Q., Wang, J., Li, W., Chen, Z.-J., & Du, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14551569
Additional file 4 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056068
Additional file 13 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056041
Additional file 7 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056077
Additional file 2 of Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice
Dessein, R., Bauduin, M., Grandjean, T., Guern, R. L., Figeac, M., Beury, D., Faure, K., Faveeuw, C., Guery, B., Gosset, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13115136
Additional file 19 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056059
Additional file 1 of Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder
Chen, C., Xu, J.-L., Gu, Z., Zhou, S.-S., Wei, G.-L., Gu, J.-L., Ma, H.-L., Feng, Y.-Q., Song, Z.-W., Yan, Z.-P., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26703271
Additional file 5 of Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice
Dessein, R., Bauduin, M., Grandjean, T., Guern, R. L., Figeac, M., Beury, D., Faure, K., Faveeuw, C., Guery, B., Gosset, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13115145
Additional file 16 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056050
Additional file 2 of Androgen-induced gut dysbiosis disrupts glucolipid metabolism and endocrinal functions in polycystic ovary syndrome
Han, Q., Wang, J., Li, W., Chen, Z.-J., & Du, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14551566
Additional file 12 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056038
Additional file 5 of Androgen-induced gut dysbiosis disrupts glucolipid metabolism and endocrinal functions in polycystic ovary syndrome
Han, Q., Wang, J., Li, W., Chen, Z.-J., & Du, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14551575
Additional file 4 of Androgen-induced gut dysbiosis disrupts glucolipid metabolism and endocrinal functions in polycystic ovary syndrome
Han, Q., Wang, J., Li, W., Chen, Z.-J., & Du, Y. (2021) · Figshare · doi:10.6084/m9.figshare.14551572
Additional file 3 of Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice
Dessein, R., Bauduin, M., Grandjean, T., Guern, R. L., Figeac, M., Beury, D., Faure, K., Faveeuw, C., Guery, B., Gosset, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13115139
Additional file 5 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056071
Additional file 14 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J. E., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056044
Additional file 10 of Linking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in paediatric haematopoietic stem cell transplantation
Vaitkute, G., Panić, G., Alber, D., Faizura-Yeop, I., Cloutman-Green, E., Swann, J., Veys, P. A., Standing, J. F., Klein, N. J., & Bajaj‐Elliott, M. (2022) · Figshare · doi:10.6084/m9.figshare.20056032
Systematic screening of tryptophan metabolism identifies site- and microbial-specific signatures of tryptophan utilization in experimental colitisPreprint
Welz, L., Alsaadi, A. I., Harris, D. M., Yu, M., Mekdoud, T., Bornhäuser, J., Springer, E., Gilloteau, C., Pothakamury, A. A., Smith, J. D., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.16.693850
Astragalus Polysaccharide Improved DSS‐Induced Colitis in Mice By Remodeling the Gut Microbiota
KHAN, I. A., Bai, Y., Li, J., Wang, Z., Xu, Z., Yuan, T., Liu, X., Zhang, Y., Zhang, C., & Xu, S. (2026) · eFood · doi:10.1002/efd2.70141
Implication du récepteur NLRP6, de la voie STING et de la cytokine BAFF dans la réponse inflammatoire pulmonaire provoquée par l’exposition aigüe à la fumée de cigarette
Nascimento, M. (2019) · theses.fr (ABES) · doi:10.70675/cdb12968z83bdz4e78za8bczd26a3f65daef
Bifidobacterium breve MN15965 Improved Bacterial Diversity, Short-Chain Fatty Acid Production, and Immune Activation in a Cyclophosphamide-Induced Immunosuppression Mouse Model
Liu, T., Zhao, X., Hui, Y., Yang, J., Li, J., Qin, H., Zhao, K., Li, J., Bian, X., Wang, X., et al. (2026) · Microorganisms · doi:10.3390/microorganisms14050949
Mechanistic insights into postbiotic-induced myelopoiesis and immune recovery after chemotherapy
Gutiérrez, F., Vasile, B., Ivir, M., Alvarez, S., & Salva, S. (2026) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/j.jpet.2026.104934 · Cited by 1
Computational Screening of Microbial Metabolites as Erythropoietin (EPO) Mimetics for the Treatment of Anemia
Hasan, M. N., Shishir, M. A., Rahman, K. A., Islam, S. B. U., Shill, M. C., Bulbul, N., Safa, A., Jime, J. S., & Fakruddin, M. (2026) · Biomedical Engineering and Computational Biology · doi:10.1177/11795972261441396
Adverse Early-Life Factors Associated with Clonal Hematopoiesis of Indeterminate Potential in Later Life
Yu, Y., Wang, J., Sun, Y., Yu, B., Tan, X., Lu, Y., Xia, F., & Wang, N. (2026) · Biomedicines · doi:10.3390/biomedicines14061366
Two cases of pancytopenia characterized by severe neutropenia induced by anti-PD-1 tislelizumab combined with chemotherapy in non-small cell lung cancer patients and a literature review
Lu, F., Yi, L., Zhu, Y., 宗文康, Zhao, F., Zhang, Y., Yang, L., & Li, Y. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1820443
A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies
Molajafari, A., Ebrahim‐Saraie, H. S., Moghadam, M. T., & Bibalan, M. H. (2026) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.70306
The Gut–Iron–Immune Axis in Severe Anaemia and Bacteraemia
Abuga, K. M., Bate, M. Y., & Atkinson, S. H. (2026) · Nutrients · doi:10.3390/nu18172753
Systematic Screening of Tryptophan Metabolism Identifies Site- and Microbiota-Dependent Signatures of Tryptophan Utilization in Experimental Colitis
Welz, L., Alsaadi, A. I., Harris, D. M. M., Yu, M., Mekdoud, T., Bornhäuser, J., Springer, E., Gilloteau, C., Pothakamury, A. A., Smith, J. D., et al. (2026) · International Journal of Tryptophan Research · doi:10.1177/11786469261472316
Microbial Influences on Leukaemia: A New Frontier in Haematological Research
Amiludin, D. N. A. A. M., Taib, W. R. W., Ismail, I. B., Saad, H. K. M., & Zulkeflee, R. H. (2026) · Malaysian Journal of Medicine and Health Sciences · doi:10.47836/mjmhs.22.s2.17
Microbiota–Inflammation Crosstalk in Myeloproliferative Neoplasms: MPN-Specific Human Data, Mechanistic Plausibility and Translational Priorities
Țîrlea, L., Lipan, L. E., & Tanase, A. D. (2026) · Biomedicines · doi:10.3390/biomedicines14092074
Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing
Chittimalli, K., Rozario, H. E., Martinez, V., McAdams, Z. L., Adkins, S., Ericsson, A. C., & Jarajapu, Y. P. R. (2026) · British Journal of Pharmacology · doi:10.1111/bph.70656 · Cited by 1
Gut irradiation and microbiota status modulate the meningeal immune landscape
Whiteley, C. H., Cytlak, U., Blair, I., Ashman, S. J., Parker, H., Illidge, T., Dyer, D. P., Travis, M. A., & Greenhalgh, A. D. (2026) · Discovery Immunology · doi:10.1093/discim/kyag019
Multikingdom gut microbiome and immune aging: A host–microbial signaling perspective
Jiang, B., Liu, T., Duan, W., & Xue, Y. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103414
Siwu Paste alleviates blood deficiency syndrome induced by cyclophosphamide and acetylphenylhydrazine in association with gut microbiota remodeling and improved splenic metabolic homeostasis
Wan, D., Feng, X., Xu, S., Du, Q., Yue, W., & Zhang, S. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.122534
Disease-specific gut microbiota–metabolite–immune networks in hematologic disorders: mechanisms, causal support, and translational strategies
Yi, L., Yuan, Y., Ma, X., Li, C., Hao, Y., Ma, Q., Liu, X., Du, X., Shao, L., Wang, S., et al. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2752469

Authors: Josefsdottir, K. S., Baldridge, M. T., Kadmon, C. S., & King, K. Y.
Affiliations: Baylor College of Medicine (US)
Washington University in St. Louis (US)
ORCID: Baldridge, Megan T.
King, Katherine Y.
Venue: Blood
Publisher: American Society of Hematology
Published: 2017-02-09
Volume: 129
Issue: 6
Pages: 729-739
ISSN: 0006-4971 (ISSN-L)
1528-0020
DOI: 10.1182/blood-2016-03-708594
PMC: PMC5301822
OpenAlex: W2554797838
Cited by: 343
References: 34
Citations by year: 2026: 25 · 2025: 42 · 2024: 46 · 2023: 31 · 2022: 50 · 2021: 43 · 2020: 40 · 2019: 30 · 2018: 25 · 2017: 11
FWCI: 11.44
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Blood (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: March of Dimes Foundation
Texas Children's Hospital
National Institutes of Health
National Cancer Institute (T32CA009547, P30CA125123)
National Institute of Allergy and Infectious Diseases (P30AI036211, R01AI141716, U19AI109725)
National Center for Research Resources (S10RR024574)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
Health Sciences › Medicine › Oncology › Neutropenia and Cancer Infections
Keywords: antibiotics, hematopoiesis, gut microbiota, fecal microbiota transplantation, germ-free mice, STAT1 signaling, T cell homeostasis, granulocyte maturation, myelosuppression
MeSH terms: Gastrointestinal Microbiome, Fecal Microbiota Transplantation, Anemia, Animals, Anti-Bacterial Agents, B-Lymphocytes, Bone Marrow Cells, Germ-Free Life, Granulocytes, Hematopoiesis, Hematopoietic Stem Cells, Leukopenia, Macrophages, Mice, Inbred C57BL, Thrombocytosis, Signal Transduction, Gene Expression, Mice, Knockout, CD8-Positive T-Lymphocytes, STAT1 Transcription Factor, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks