The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota
Open accessAbstract
Key Points: Antibiotics cause multilineage alterations in murine hematopoiesis, with marked suppression of multipotent progenitors. Suppression of bone marrow populations results from depletion of intestinal microbiota.
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“The gut microbiota constantly communicates with vital organ systems of the host, such as the brain6, bone marrow7, vasculature8, kidney9, immune system10 and autonomic nervous system (ANS)11,12.”
From The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease (2018) · cites this paper as [7]
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Cites
Role of the microbiota in immunity and inflammation.
Belkaid, Y., & Hand, T. W. (2014) · Cell · doi:10.1016/j.cell.2014.03.011 · Cited by 5,385
Wilson, A., Laurenti, E., Oser, G., van der Wath, R. C., Blanco-Bose, W., Jaworski, M., Offner, S., Dunant, C. F., Eshkind, L., Bockamp, E., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.048 · Cited by 1,908
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
Abt, M. C., Osborne, L. C., Monticelli, L. A., Doering, T. A., Alenghat, T., Sonnenberg, G. F., Paley, M. A., Antenus, M., Williams, K. L., Erikson, J., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.04.011 · Cited by 993
Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
Baldridge, M. T., King, K. Y., Boles, N. C., Weksberg, D. C., & Goodell, M. A. (2010) · Nature · doi:10.1038/nature09135 · Cited by 877
Self-citationNeutrophil ageing is regulated by the microbiome
Zhang, D., Chen, G., Manwani, D., Mortha, A., Xu, C., Faith, J. J., Burk, R. D., Kunisaki, Y., Jang, J.-E., Scheiermann, C., et al. (2015) · Nature · doi:10.1038/nature15367 · Cited by 839
Clonal dynamics of native haematopoiesis
Sun, J., Ramos, A., Chapman, B., Johnnidis, J. B., Le, L., Ho, Y.-J., Klein, A. M., Hofmann, O., & Camargo, F. D. (2014) · Nature · doi:10.1038/nature13824 · Cited by 803
The microbiome in infectious disease and inflammation
Honda, K., & Littman, D. R. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-074937 · Cited by 791
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
Busch, K., Klapproth, K., Barile, M., Flossdorf, M., Holland-Letz, T., Schlenner, S. M., Reth, M., Höfer, T., & Rodewald, H.-R. (2015) · Nature · doi:10.1038/nature14242 · Cited by 769
Pietras, E. M., Reynaud, D., Kang, Y.-A., Carlin, D., Calero-Nieto, F. J., Leavitt, A. D., Stuart, J. M., Göttgens, B., & Passegué, E. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.05.003 · Cited by 723
Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection
Khosravi, A., Yáñez, A., Price, J. G., Chow, A. T., Mérad, M., Goodridge, H. S., & Mazmanian, S. K. (2014) · Cell Host & Microbe · doi:10.1016/j.chom.2014.02.006 · Cited by 668
Cited by
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Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
Pickard, J. M., Zeng, M. Y., Caruso, R., & Núñez, G. (2017) · Immunological Reviews · doi:10.1111/imr.12567 · Cited by 1,699
Microbes, Metabolites, and the Gut-Lung Axis
Dang, A. T., & Marsland, B. J. (2019) · Mucosal Immunology · doi:10.1038/s41385-019-0160-6 · Cited by 1,028
The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease
Yang, T., Richards, E. M., Pepine, C. J., & Raizada, M. K. (2018) · Nature Reviews Nephrology · doi:10.1038/s41581-018-0018-2 · Cited by 753
Kennedy, E. A., King, K. Y., & Baldridge, M. T. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01534 · Cited by 602
Self-citationVaccination in the elderly: The challenge of immune changes with aging
Ciabattini, A., Nardini, C., Santoro, F., Garagnani, P., Franceschi, C., & Medaglini, D. (2018) · Seminars in Immunology · doi:10.1016/j.smim.2018.10.010 · Cited by 411
Metadata
- Authors
- Josefsdottir, K. S., Baldridge, M. T., Kadmon, C. S., & King, K. Y.
- Affiliations
- Baylor College of Medicine (US)
- Washington University in St. Louis (US)
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2017-02-09
- Volume
- 129
- Issue
- 6
- Pages
- 729-739
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- PMC
- PMC5301822
- OpenAlex
- W2554797838
- Cited by
- 343
- References
- 34
- Citations by year
- 2026: 25 · 2025: 42 · 2024: 46 · 2023: 31 · 2022: 50 · 2021: 43 · 2020: 40 · 2019: 30 · 2018: 25 · 2017: 11
- FWCI
- 11.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Blood (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- March of Dimes Foundation
- Texas Children's Hospital
- National Institutes of Health
- National Cancer Institute (T32CA009547, P30CA125123)
- National Institute of Allergy and Infectious Diseases (P30AI036211, R01AI141716, U19AI109725)
- National Center for Research Resources (S10RR024574)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Health Sciences › Medicine › Oncology › Neutropenia and Cancer Infections
- Keywords
- antibiotics, hematopoiesis, gut microbiota, fecal microbiota transplantation, germ-free mice, STAT1 signaling, T cell homeostasis, granulocyte maturation, myelosuppression
- MeSH terms
- Gastrointestinal Microbiome, Fecal Microbiota Transplantation, Anemia, Animals, Anti-Bacterial Agents, B-Lymphocytes, Bone Marrow Cells, Germ-Free Life, Granulocytes, Hematopoiesis, Hematopoietic Stem Cells, Leukopenia, Macrophages, Mice, Inbred C57BL, Thrombocytosis, Signal Transduction, Gene Expression, Mice, Knockout, CD8-Positive T-Lymphocytes, STAT1 Transcription Factor, Mice
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