The microbiome in infectious disease and inflammation

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

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An obesity-associated gut microbiome with increased capacity for energy harvest

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A human gut microbial gene catalogue established by metagenomic sequencing

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Human gut microbes associated with obesity

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Diversity of the Human Intestinal Microbial Flora

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A core gut microbiome in obese and lean twins

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Enterotypes of the human gut microbiome

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Linking long-term dietary patterns with gut microbial enterotypes

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Autophagy fights disease through cellular self-digestion

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

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Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

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Regulatory T Cells and Immune Tolerance

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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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The gut microbiota shapes intestinal immune responses during health and disease

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Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

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Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

Chen, W., Jin, W., Hardegen, N. J., Lei, K.-J., Li, L., Marinos, N. J., McGrady, G., & Wahl, S. M. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030152 · Cited by 4,678 · see citing works

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

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Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.033 · Cited by 4,554 · see citing works

Autophagy and Viruses: Adversaries or Allies?

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<i>Faecalibacterium prausnitzii</i> is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

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Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

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Interleukin-10-deficient mice develop chronic enterocolitis

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Intestinal mucosal barrier function in health and disease

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Induction of Colonic Regulatory T Cells by Indigenous <i>Clostridium</i> Species

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Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila

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Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

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Transforming growth factor-β induces development of the TH17 lineage

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A Genome-Wide Association Study Identifies <i>IL23R</i> as an Inflammatory Bowel Disease Gene

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Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICA

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Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

Coombes, J. L., Siddiqui, K. R. R., Arancibia-Cárcamo, C. V., Hall, J. A., Sun, C., Belkaid, Y., & Powrie, F. M. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070590 · Cited by 2,708 · see citing works

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

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The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

Brown, A. J., Goldsworthy, S. M., Barnes, A. A., Eilert, M. M., Tcheang, L., Daniels, D., Muir, A. I., Wigglesworth, M. J., Kinghorn, I., Fraser, N. J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211609200 · Cited by 2,409 · see citing works

Bifidobacteria can protect from enteropathogenic infection through production of acetate

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A microbial symbiosis factor prevents intestinal inflammatory disease

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Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach

Manichanh, C., Rigottier-Gois, L., Bonnaud, E., Gloux, K., Pelletier, E., Frangeul, L., Nalin, R., Jarrin, C., Chardon, P., Marteau, P., et al. (2006) · Gut · doi:10.1136/gut.2005.073817 · Cited by 2,277 · see citing works

Inducible Foxp3 ⁺ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

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The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

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IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

Zhou, L., Ivanov, I. I., Spolski, R. J., Min, R., Shenderov, K., Egawa, T., Levy, D. E., Leonard, W. J., & Littman, D. R. (2007) · Nature Immunology · doi:10.1038/ni1488 · Cited by 2,134 · see citing works

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

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NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

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Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

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Reciprocal T _H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

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Regulation of short-chain fatty acid production

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

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Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

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TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

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Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract

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Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

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The Phylogeny of the Genus Clostridium: Proposal of Five New Genera and Eleven New Species Combinations

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CX 3 CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

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Interactions between commensal intestinal bacteria and the immune system

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The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

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Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

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Innate IL-17-producing cells: the sentinels of the immune system

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Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

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High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

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Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

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Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

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Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

Hirasawa, A., Tsumaya, K., Awaji, T., Katsuma, S., Adachi, T., Yamada, M., Sugimoto, Y., Miyazaki, S., & Tsujimoto, G. (2004) · Nature Medicine · doi:10.1038/nm1168 · Cited by 1,535 · see citing works

TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology

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Negative regulation of Toll-like receptor-mediated immune responses

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Unravelling the effects of the environment and host genotype on the gut microbiome

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Immune adaptations that maintain homeostasis with the intestinal microbiota

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Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

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The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

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Symbiotic bacteria direct expression of an intestinal bactericidal lectin

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

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Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

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Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

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Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae

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The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

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The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

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Diet, gut microbiota and immune responses

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The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

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Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

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