Cited by 353Cytokine Signaling Pathways and InteractionsImmune cells in cancerAcute Myeloid Leukemia Research

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Colony-stimulating factor-1 receptor

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Sherr, CJ·1990·Blood

DOI 10.1182/blood.v75.1.1.bloodjournal7511

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Abstract

The c-fms protooncogene maps near the CSF-1 locus on human chromosome 5 at

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Crossref · 10.1182/blood.v75.1.1.bloodjournal7511

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Xu, F., Taki, T., Yang, H. W., Hanada, R., Hongo, T., Ohnishi, Kobayashi, M., Bessho, F., Yanagisawa, M., & Hayashi, Y. (1999) · British Journal of Haematology · doi:10.1111/j.1365-2141.1999.01284.x · Cited by 176
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Background
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Background
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Background
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Background
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Background
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Background
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Background
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BackgroundInfluential
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Vassal, G., Koscielny, S., Challine, D., et al. (1995) · Cancer Chemotherapy and Pharmacology · doi:10.1007/bf00688324 · Cited by 101
Syndecan-1 regulates the biological activities of interleukin-34
Ségaliny, A. I., Brion, R., Mortier, E., Maillasson, M., Chérel, M., Jacques, Y., Goff, B. L., & Heymann, D. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.01.023 · Cited by 97
“The homodimeric cytokines M-CSF or IL-34 bind in a close way to the extracellular domain of M-CSFR, but with a different binding mode [9,10], leading to receptor dimerization and differential auto-phosphorylation on its eight tyrosine residues [11].”
Background
Tec Kinase Associates with c-kit and Is Tyrosine Phosphorylated and Activated following Stem Cell Factor Binding
Tang, B., Mano, H., Yi, T., & Ihle, J. N. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.8432-8437.1994 · Cited by 102
“c-kit is related to c-fins, the CSF-1 receptor, which is primarily expressed in macrophages (20).”
Background
Enhancement of human immunodeficiency virus type 1‐DNA vaccine potency through incorporation of T‐helper 1 molecular adjuvants
Calarota, S. A., & Weiner, D. B. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00150.x · Cited by 95
“M-CSF has been shown to be a regulator of the growth, differentiation, and function of mononuclear phagocytes (34).”
Background
The hematopoietic cytokine, colony‐stimulating factor 1, is also a growth factor in the CNS: Congenital absence of CSF‐1 in mice results in abnormal microglial response and increased neuron vulnerability to injury
Berezovskaya, O. L., Maysinger, D., & FEDOROFF, S. (1995) · International Journal of Developmental Neuroscience · doi:10.1016/0736-5748(95)00013-7 · Cited by 94
Chronic myelomonocytic leukemia: Tel-a-kinase what Ets all about
Sawyers, C. L., & Denny, C. T. (1994) · Cell · doi:10.1016/0092-8674(94)90307-7 · Cited by 92
Macrophage colony-stimulating factor mediates astrocyte-induced microglial ramification in human fetal central nervous system culture.
Liu, W., Brosnan, C. F., Dickson, D. W., & Lee, S. C. (1994) · PubMed Central · Cited by 91
The peripheral lymph node homing receptor, LECAM-1, is involved in CD18-independent adhesion of human neutrophils to endothelium
Hallmann, R., Jutila, M. A., Smith, C. W., et al. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)90511-5 · Cited by 90
Macrophage colony-stimulating factor (CSF-1) enhances invasiveness in CSF-1 receptor-positive carcinoma cell lines.
Filderman, A. E., Bruckner, A., Kacinski, B. M., et al. (1992) · PubMed · Cited by 89
Expression of mRNA Encoding the Macrophage Colony-Stimulating Factor Receptor (c- fms ) is Controlled by a Constitutive Promoter and Tissue-Specific Transcription Elongation
Yue, X., Favot, P., Dunn, T. L., Cassady, A. I., & Hume, D. A. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3191 · Cited by 87
FLT3: Receptor and Ligand. Biology and Potential Clinical Application
Shurin, M. R. (1998) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(97)00035-x · Cited by 84
Development of Osteoclasts From Embryonic Stem Cells Through a Pathway That Is c-fms but not c-kit Dependent
Yamane, T., Kunisada, T., Yamazaki, H., Era, T., Nakano, T., & Hayashi, S.-I. (1997) · Blood · doi:10.1182/blood.v90.9.3516 · Cited by 82
Neuronal and microglial regulators of cortical wiring: usual and novel guideposts
Squarzoni, P. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00248 · Cited by 91
Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples
Shih, L.-Y., Liang, D.-C., Huang, C.-F., Chang, Y.-T., Lai, C.-L., Lin, T., Yang, C.-P., Hung, I., Liu, H., Jaing, T.-H., et al. (2007) · Leukemia · doi:10.1038/sj.leu.2404995 · Cited by 79
Localization of a CDKN2 gene in linkage group V of Xiphophorus fishes defines it as a candidate for the DIFF tumor suppressor
Kazianis, S., Gutbrod, H., Nairn, R. S., McEntire, B. B., Coletta, L. D., Walter, R. B., Borowsky, R. L., Woodhead, A. D., Setlow, R. B., Schartl, M., et al. (1998) · Genes Chromosomes and Cancer · doi:10.1002/(sici)1098-2264(199807)22:3 · Cited by 60
Macrophage Phenotype in Mice Deficient in Both Macrophage-Colony–Stimulating Factor (Op) and Apolipoprotein E
de Villiers, W. J. S., Smith, J. D., Miyata, M., Dansky, H. M., Darley, E., & Gordon, S. (1998) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.18.4.631 · Cited by 80
Mitogenic Signals and Transforming Potential of Nyk, a Newly Identified Neural Cell Adhesion Molecule-Related Receptor Tyrosine Kinase
Lei, L., & Kung, H.-J. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.12.6582 · Cited by 81
“contain endogenous Fms and do not respond to treatment with human CSF-1 (84).”
Background
PU.1 but not ets-2 is essential for macrophage development from embryonic stem cells
Henkel, G., McKercher, Sr., Yamamoto, H., Anderson, K., Oshima, R., & Maki, R. (1996) · Blood · doi:10.1182/blood.v88.8.2917.bloodjournal8882917 · Cited by 76
Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1
Metcalf, D., Ws, A., Elefanty, A. G., et al. (1999) · Leukemia · doi:10.1038/sj.leu.2401440 · Cited by 74
Hematopoietic lineage commitment: Role of transcription factors
Kehrl, J. H. (1995) · Stem Cells · doi:10.1002/stem.5530130304 · Cited by 69
Identification of a cell-surface antigen associated with activated T lymphoblasts and activated platelets
Sutherland, D. R., Yeo, E. L., Ryan, A., Mills, G., Bailey, D. J., & Baker, M. A. (1991) · Blood · doi:10.1182/blood.v77.1.84.bloodjournal77184 · Cited by 81
“for 2 more days (3) before analysis on FACS II.”
Background
Biochemical analysis of the ligand for the neu oncogenic receptor
Yarden, Y., & Peles, E. (1991) · Biochemistry · doi:10.1021/bi00228a027 · Cited by 71
Emergence of T, B, and Myeloid Lineage-Committed as well as Multipotent Hemopoietic Progenitors in the Aorta-Gonad- Mesonephros Region of Day 10 Fetuses of the Mouse
Ohmura, K., Kawamoto, H., Fujimoto, S., Ozaki, S., Nakao, K., & Katsura, Y. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.9.4788 · Cited by 69
Cytokines: From clone to clinic
Aggarwal, B. B., & Pócsik, É. (1992) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(92)90002-e · Cited by 69
Emergence of T Cell Progenitors Without B Cell or Myeloid Differentiation Potential at the Earliest Stage of Hematopoiesis in the Murine Fetal Liver
Kawamoto, H., Ohmura, K., Fujimoto, S., & Katsura, Y. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.5.2725 · Cited by 68

Authors: Sherr, C.
Venue: Blood
Publisher: American Society of Hematology
Published: 1990-01-01
Volume: 75
Issue: 1
Pages: 1-12
ISSN: 0006-4971 (ISSN-L)
1528-0020
DOI: 10.1182/blood.v75.1.1.bloodjournal7511
OpenAlex: W2403681274
Cited by: 353
References: 0
Citations by year: 2024: 1 · 2023: 5 · 2022: 1 · 2021: 7 · 2019: 4 · 2018: 5 · 2017: 4 · 2016: 5 · 2015: 3 · 2014: 6 · 2013: 8 · 2012: 3
FWCI: 18.95
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Blood (publishedVersion)
PubMed (publishedVersion)
Funders: Howard Hughes Medical Institute
American Lebanese Syrian Associated Charities (P30CA21765, CA 21765)
National Institutes of Health (CA21765))
National Cancer Institute (P 30CA 21765, P30CA021765)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Cytokine Signaling Pathways and Interactions
Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
Health Sciences › Medicine › Hematology › Acute Myeloid Leukemia Research
Keywords: colony-stimulating factor 1 receptor, CSF1R, hematopoietic growth factor receptors, mesenchymal stem cells, osteoclastogenesis, receptor tyrosine kinase
MeSH terms: Cell Transformation, Neoplastic, Chromosomes, Human, Pair 5, Humans, Protein-Tyrosine Kinases, Proto-Oncogene Proteins, Receptors, Cell Surface, Signal Transduction, Down-Regulation, Receptor, Macrophage Colony-Stimulating Factor, Receptors, Platelet-Derived Growth Factor

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