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Cited by 337

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Serum Transferrin Receptor and Transferrin Receptor-Ferritin Index Identify Healthy Subjects With Subclinical Iron Deficits

Suominen, Pauli, Punnonen, Kari, Rajamäki, Allan, Irjala, Kerttu·1998·Blood

Abstract

Despite the established utility of serum transferrin receptor (sTfR), serum ferritin, and the sTfR/log ferritin ratio (TfR-F Index) in the diagnosis of iron deficiency (ID) anemia, the numeric values of these parameters, which are indicative of subclinical ID, remain to be clearly defined. In this study, 65 apparently healthy nonanemic adults (22 men and 43 women) were treated with 3 months of oral iron supplementation to evaluate its effect on parameters reflecting iron status and to determine the prevalence of subclinical iron deficiency in apparently healthy adults. Significant supplementation-induced changes were observed in sTfR, ferritin, and TfR-F Index values in women, whereas in men, none of the studied parameters showed any significant change. Iron-deficient erythropoiesis (IDE) was not observed in men, but was found in 17 women (40%). Although individuals with a compromised iron status may be represented in substantial numbers in conventional reference populations, they can be readily identified using sTfR, ferritin, and TfR-F Index determinations. © 1998 by The American Society of Hematology.

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Crossref · 10.1182/blood.v92.8.2934

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Metadata

Authors
Suominen, P., Punnonen, K., Rajamäki, A., & Irjala, K.
Venue
Blood
Published
1998-10-15
Volume
92
Issue
8
Pages
2934-2939
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
OpenAlex
W1638373457
Cited by
337
References
2
FWCI
5.49
Type
journal article
Language
en
Open access
closed

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