How do we manage iron deficiency after blood donation?

Kiss, Joseph E.; Vassallo, Ralph R.

doi:10.1111/bjh.15136

Cited by 93Iron Metabolism and DisordersBlood donation and transfusion practicesBlood transfusion and management

How do we manage iron deficiency after blood donation?

Kiss, Joseph E., Vassallo, Ralph R.·2018·British Journal of Haematology

DOI 10.1111/bjh.15136

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Abstract

Summary: Blood donors and the RBCs and other components they willingly provide are essential in the delivery of healthcare in all parts of the world. Nearly 70% of donated blood comes from repeat or committed donors. The amount of iron removed in the 10 min or so it takes to withdraw a unit of blood (500 ml, plus 25 ml for testing) requires over 24 weeks to replace on a “standard” diet, i.e., without added iron in the form of supplements The cumulative effect of repeat blood donations without adequate iron replacement or a longer wait between donations results in iron deficiency (ID) in many donors, low haemoglobin deferral (~8% of donation attempts), and frank anaemia in some. Moreover, ID can be associated with side effects that can impact a blood donor's health, such as fatigue, cognitive changes and other neuromuscular symptoms. In an effort to better identify and prevent ID, blood collection agencies are recommending various strategies, including changes in the donation interval, donation frequency, testing of iron status and iron supplementation. In this review, we present the evidence basis for these strategies and suggest our own approaches to improving iron balance in blood donors.

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TMPRSS6 genetic variants modulate iron and hematologic traits in several genome-wide association studies, alter hepcidin levels in normal subjects and might confer susceptibility/resistance to iron deficiency, as observed in blood donors.
“TMPRSS6 genetic variants modulate iron and hematologic traits in several genome-wide association studies,58 alter hepcidin levels in normal subjects86 and might confer susceptibility/resistance to iron deficiency, as observed in blood donors.87”
From Iron metabolism and iron disorders revisited in the hepcidin era (2020) · cites this paper as [87]

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Quantification of body iron and iron absorption in the REDS‐II D onor I ron S tatus E valuation (RISE) study
Kiss, J. E., Birch, R. J., Steele, W. R., Wright, D. J., & Cable, R. G. (2017) · Transfusion · doi:10.1111/trf.14133 · Cited by 29 · see citing works
Self-citation
Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy
Mast, A. E., Schlumpf, K. S., Wright, D. J., Johnson, B. R., Glynn, S. A., Busch, M. P., Olbina, G., Westerman, M., Nemeth, E., Ganz, T., et al. (2013) · Haematologica · doi:10.3324/haematol.2012.070979 · Cited by 25 · see citing works
Prevalence of blood donor iron deficiency and feasibility ferritin‐based iron replacement: a blood collection agency‐based study
Gorlin, J. B., Katz, L. M., Elsmore, D., Kirbach, K., Erickson, Y. O., Hove, A., Black, C., & Walsh‐Jahnke, R. (2016) · Vox Sanguinis · doi:10.1111/vox.12408 · Cited by 22 · see citing works
Estimates of total body iron indicate 19 mg and 38 mg oral iron are equivalent for the mitigation of iron deficiency in individuals experiencing repeated phlebotomy
Bialkowski, W., Kiss, J. E., Wright, D. J., Cable, R. G., Birch, R. J., D'Andrea, P., Bryant, B. J., Spencer, B. R., & Mast, A. E. (2017) · American Journal of Hematology · doi:10.1002/ajh.24784 · Cited by 21 · see citing works
Self-citation
The operational implications of donor behaviors following enrollment in STRIDE (Strategies to Reduce Iron Deficiency in blood donors)
Cable, R. G., Birch, R. J., Spencer, B. R., Wright, D. J., Bialkowski, W., Kiss, J. E., Rios, J. A., Bryant, B. J., & Mast, A. E. (2017) · Transfusion · doi:10.1111/trf.14226 · Cited by 21 · see citing works
Self-citation
Teenage Blood Donors: Are We Asking Too Little and Taking Too Much?
Bloch, E. M., Mast, A. E., Josephson, C. D., Klein, H. G., & Eder, A. F. (2017) · PEDIATRICS · doi:10.1542/peds.2016-2955 · Cited by 20 · see citing works
Postdonation iron replacement for maintaining iron stores in female whole blood donors in routine donor practice: results of two feasibility studies in Australia
Pasricha, S., Marks, D. C., Salvin, H. E., Brama, T., Keller, A. J., Pink, J., & Speedy, J. (2017) · Transfusion · doi:10.1111/trf.14173 · Cited by 17 · see citing works
Pathophysiology of Iron Homeostasis
Brittenham, G. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35762-3.00035-4 · Cited by 15 · see citing works
The association between frequency of blood donation and the occurrence of low birthweight, preterm delivery, and stillbirth: a retrospective cohort study
Germain, M., Delage, G., Robillard, P., Katz, L. M., & Grégoire, Y. (2016) · Transfusion · doi:10.1111/trf.13762 · Cited by 14 · see citing works
Serum ferritin in plateletpheresis and whole blood donors
Duggan, F., O’Sullivan, K., Power, J. P., Healy, M., & Murphy, W. G. (2016) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2016.06.004 · Cited by 14 · see citing works
Impact of informing donors of low ferritin results
Goldman, M., Uzicanin, S., Scalia, J., Scalia, V., & O’Brien, S. F. (2016) · Transfusion · doi:10.1111/trf.13691 · Cited by 12 · see citing works
Effects of oral supplementation of iron on hepcidin blood concentrations among non‐anaemic female blood donors: a randomized controlled trial
Waldvogel, S., Rochat, B., Peduzzi, D., Vaucher, P., Tissot, J., & Favrat, B. (2015) · Vox Sanguinis · doi:10.1111/vox.12348 · Cited by 8 · see citing works
Hepcidin/Ferritin Quotient Helps to Predict Spontaneous Recovery from Iron Loss following Blood Donation
Lotfi, R., Kroll, C., Plonné, D., Jahrsdörfer, B., & Schrezenmeier, H. (2015) · Transfusion Medicine and Hemotherapy · doi:10.1159/000440825 · Cited by 8 · see citing works

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Iron deficiency
Pasricha, S.-R., Tye-Din, J., Muckenthaler, M. U., & Swinkels, D. W. (2021) · The Lancet · doi:10.1016/s0140-6736(20)32594-0 · Cited by 1,069 · see citing works
Iron metabolism and iron disorders revisited in the hepcidin era
Camaschella, C., Nai, A., & Silvestri, L. (2020) · Haematologica · doi:10.3324/haematol.2019.232124 · Cited by 734 · see citing works
“TMPRSS6 genetic variants modulate iron and hematologic traits in several genome-wide association studies,(58) alter hepcidin levels in normal subjects(86) and might confer susceptibility/resistance to iron deficiency, as observed in blood donors.(87) Other rare recessive disorders of the transferrin receptor pathway –…”
Iron deficiency
Camaschella, C. (2019) · Blood · doi:10.1182/blood-2018-05-815944 · Cited by 702 · see citing works
Iron deficiency anaemia revisited
Cappellini, M. D., Musallam, K. M., & Taher, A. T. (2019) · Journal of Internal Medicine · doi:10.1111/joim.13004 · Cited by 558 · see citing works
Iron Deficiency and Iron Deficiency Anemia: A Comprehensive Overview of Established and Emerging Concepts
Kolarš, B., Mijatović Jovin, V., Živanović, N., Minaković, I., Gvozdenović, N., Dickov Kokeza, I., & Lesjak, M. (2025) · Pharmaceuticals · doi:10.3390/ph18081104 · Cited by 71 · see citing works
L-Arginine and Nitric Oxide in Vascular Regulation—Experimental Findings in the Context of Blood Donation
Kurhaluk, N., & Tkaczenko, H. (2025) · Nutrients · doi:10.3390/nu17040665 · Cited by 62 · see citing works
Elevated risk for iron depletion in high‐school age blood donors
Spencer, B. R., Bialkowski, W., Creel, D. V., Cable, R. G., Kiss, J. E., Stone, M., McClure, C., Kleinman, S. H., Glynn, S. A., & Mast, A. E. (2019) · Transfusion · doi:10.1111/trf.15133 · Cited by 49 · see citing works
Self-citation
First results of a ferritin‐based blood donor deferral policy in the Netherlands
Vinkenoog, M., van den Hurk, K., van Kraaij, M., van Leeuwen, M., & Janssen, M. P. (2020) · Transfusion · doi:10.1111/trf.15906 · Cited by 49 · see citing works
Association of blood donation with iron deficiency among adolescent and adult females in the United States: a nationally representative study
Patel, E. U., White, J. L., Bloch, E. M., Grabowski, M. K., Gehrie, E. A., Lokhandwala, P. M., Brunker, P. A. R., Goel, R., Shaz, B. H., Ness, P. M., et al. (2019) · Transfusion · doi:10.1111/trf.15179 · Cited by 38 · see citing works
Reticulocytes in donor blood units enhance red blood cell alloimmunization
Thomas, T. A., Qiu, A., Kim, C. Y., Gordy, D. E., Miller, A., Tredicine, M., Dzieciątkowska, M., Zotti, F. D., Hod, E. A., D’Alessandro, A., et al. (2023) · Haematologica · doi:10.3324/haematol.2023.282815 · Cited by 33 · see citing works
Effectiveness of ferritin-guided donation intervals in whole-blood donors in the Netherlands (FIND'EM): a stepped-wedge cluster-randomised trial
Meulenbeld, A., Ramondt, S., Sweegers, M. G., Quee, F. A., Prinsze, F. J., Hoogendijk, E. O., Swinkels, D. W., & van den Hurk, K. (2024) · The Lancet · doi:10.1016/s0140-6736(24)01085-7 · Cited by 33 · see citing works
Absolute and functional iron deficiency: Biomarkers, impact on immune system, and therapy
Iriarte‐Gahete, M., Tarancón‐Díez, L., Garrido‐Rodríguez, V., Leal, M., & Pacheco, Y. M. (2024) · Blood Reviews · doi:10.1016/j.blre.2024.101227 · Cited by 35 · see citing works
Surface modification of SiO2 nanoparticles for bacterial decontaminations of blood products
Alavi, M., Hamblin, M. R., Mozafari, M. R., de Menezes, I. R. A., & Coutinho, H. D. M. (2022) · Cellular Molecular and Biomedical Reports · doi:10.55705/cmbr.2022.338888.1039 · Cited by 29 · see citing works
Variations in hemoglobin measurement and eligibility criteria across blood donation services are associated with differing low‐hemoglobin deferral rates: a BEST Collaborative study
Zalpuri, S., Romeijn, B., Allara, E., Goldman, M., Kamel, H. T., Gorlin, J. B., Vassallo, R. R., Grégoire, Y., Goto, N., Flanagan, P., et al. (2020) · Transfusion · doi:10.1111/trf.15676 · Cited by 24 · see citing works
Self-citation
Complications of blood donation reported to haemovigilance systems: analysis of eleven years of international surveillance
Wiersum‐Osselton, J. C., Politis, C., Richardson, C., Goto, N., Grouzi, E., Marano, G., & Land, K. J. (2020) · Vox Sanguinis · doi:10.1111/vox.13048 · Cited by 23 · see citing works
Longer-term efficiency and safety of increasing the frequency of whole blood donation (INTERVAL): extension study of a randomised trial of 20 757 blood donors
Kaptoge, S., Angelantonio, E. D., Moore, C., Walker, M., Armitage, J., Ouwehand, W. H., Roberts, D. J., Danesh, J., Thompson, S. G., Kaptoge, S., et al. (2019) · The Lancet Haematology · doi:10.1016/s2352-3026(19)30106-1 · Cited by 22 · see citing works
Ferritin testing to characterize and address iron deficiency in young donors
Vassallo, R. R., Bravo, M. D., & Kamel, H. T. (2018) · Transfusion · doi:10.1111/trf.14921 · Cited by 21 · see citing works
Self-citation
The Efficacy of Bone Wax in Reduction of Perioperative Blood Loss in Total Hip Arthroplasty via Direct Anterior Approach
Mortazavi, S. M. J., Razzaghof, M., Ghadimi, E., Seyedtabaei, S. M. M., Ardakani, M. V., & Moharrami, A. (2022) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.22.00376 · Cited by 19 · see citing works
The effect of donation activity dwarfs the effect of lifestyle, diet and targeted iron supplementation on blood donor iron stores
Lobier, M., Castrén, J., Niittymäki, P., Palokangas, E., Partanen, J., & Arvas, M. (2019) · PLoS ONE · doi:10.1371/journal.pone.0220862 · Cited by 19 · see citing works
Whole Blood Donor Iron Management Across Europe: Experiences and Challenges in Four Blood Establishments
van den Hurk, K., Arvas, M., Roberts, D. J., Castrén, J., & Erikstrup, C. (2024) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2024.150860 · Cited by 18 · see citing works
Longer-term efficiency and safety of increasing the frequency of whole blood donation (INTERVAL): extension study of a randomised trial of 20 757 blood donors.
Kaptoge, S. K., Angelantonio, E. D., Moore, C. S., Walker, M. R., Armitage, J., Ouwehand, W. H., Roberts, D. J., Danesh, J., Thompson, S. G., & INTERVAL Trial Group (2019) · Apollo (University of Cambridge) · doi:10.17863/cam.40730 · Cited by 18 · see citing works
Iron deficiency–related symptoms in whole blood donors: a systematic review
Zalpuri, S., Schotten, N., Baart, A. M., van de Watering, L. M., van den Hurk, K., & van Kraaij, M. G. J. (2019) · Transfusion · doi:10.1111/trf.15509 · Cited by 16 · see citing works
The health impacts of blood donation: a systematic review of donor and non-donor perceptions.
Thorpe, R. D., Masser, B., Coundouris, S. P., Hyde, M. K., Kruse, S. P., & Davison, T. E. (2024) · PubMed Central · doi:10.2450/bloodtransfus.494 · Cited by 14 · see citing works
The Use of Iron-Enriched Yeast for the Production of Flatbread
Nowosad, K., & Sujka, M. (2021) · Molecules · doi:10.3390/molecules26175204 · Cited by 13 · see citing works
Individualized risk trajectories for iron‐related adverse outcomes in repeat blood donors
Russell, W. A., Scheinker, D., & Custer, B. (2021) · Transfusion · doi:10.1111/trf.16740 · Cited by 12 · see citing works
Ferritin-guided iron supplementation as an alternative or complement to prolonged blood donation intervals (FORTE): a double-blind, randomised, controlled trial
Karregat, J. H. M., Meulenbeld, A., Quee, F. A., Novotny, V. M. J., Swinkels, D. W., van den Born, B. H., Zaaijer, H. L., Twisk, J. W. R., & van den Hurk, K. (2025) · The Lancet Haematology · doi:10.1016/s2352-3026(25)00167-x · Cited by 11 · see citing works
Recovery of Iron Stores After Adolescents Donate Blood
Vassallo, R. R., Hilton, J. F., Bravo, M. D., Vittinghoff, E., Custer, B., & Kamel, H. T. (2020) · PEDIATRICS · doi:10.1542/peds.2019-3316 · Cited by 11 · see citing works
Self-citation
Ferritin Trajectories over Repeated Whole Blood Donations: Results from the FIND+ Study
Moazzen, S., Sweegers, M. G., Janssen, M. P., Hogema, B. M., Hoekstra, T., & van den Hurk, K. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11133581 · Cited by 12 · see citing works
Effects of repeated blood donation on iron status of blood donors in Zimbabwe: A cross‐sectional study
Vhanda, D., Chinowaita, F., Nkomo, S. Z., Timire, C., & Kouamou, V. (2021) · Health Science Reports · doi:10.1002/hsr2.426 · Cited by 10 · see citing works
Donor iron depletion: beneficial or burdensome?
Vassallo, R. R. (2019) · Transfusion · doi:10.1111/trf.15282 · Cited by 10 · see citing works
Self-citation
The association between eating frequency with alertness and gastrointestinal complaints in nurses during the night shift
de Rijk, M. G., van Eekelen, A. P. J., Kaldenberg, E., Boesveldt, S., Woerd, W. T., Holwerda, T., Lansink, C. J. M., Feskens, E. J. M., & de Vries, J. H. M. (2021) · Journal of Sleep Research · doi:10.1111/jsr.13306 · Cited by 11 · see citing works
Macronutrient intake and alertness during night shifts – the time interval matters
de Rijk, M. G., van Eekelen, A. P. J., Boesveldt, S., Kaldenberg, E., Holwerda, T., Lansink, C. J. M., Feskens, E. J. M., & de Vries, J. H. M. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1245420 · Cited by 9 · see citing works
The contribution and potential of older blood donors in Asia Pacific regions
Fung, Y. L., Lee, C. K., Kwon, S., Soedarmono, Y., Satake, M., Alcantara, R., & Donkin, R. (2021) · Transfusion Medicine · doi:10.1111/tme.12845 · Cited by 8 · see citing works
Should We Stop Collecting the Preoperative Autologous Blood before Bone Marrow Harvest?
Lysák, D., Hejretová, L., Hrabětová, M., & Jindra, P. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10102134 · Cited by 8 · see citing works
Promoting awareness of donation‐related iron depletion among high risk blood donors
France, J. L., France, C. R., Rebosa, M., Shaz, B. H., & Kessler, D. A. (2021) · Transfusion · doi:10.1111/trf.16694 · Cited by 8 · see citing works
First do no harm: iron loss in whole blood donors
Sweegers, M. G., van Kraaij, M. G. J., & van den Hurk, K. (2019) · ISBT Science Series · doi:10.1111/voxs.12527 · Cited by 8 · see citing works
Reticulocytes in donor RBC units enhance RBC alloimmunizationPreprint
Thomas, T. A., Qiu, A., Kim, C. Y., Gordy, D. E., Miller, A., Tredicine, M., Dzieciątkowska, M., Zotti, F. D., Hod, E. A., D’Alessandro, A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.25.525560 · Cited by 8 · see citing works
The value of genetic data from 665,460 individuals in managing iron deficiency anaemia and suitability to donate blood
Toivonen, J., Allara, E., FinnGen, Castrén, J., Angelantonio, E. D., & Arvas, M. (2023) · Vox Sanguinis · doi:10.1111/vox.13564 · Cited by 7 · see citing works
Eligibility Considerations for Female Whole Blood Donors: Hemoglobin Levels and Iron Status in a Nationally Representative Population
Spencer, B. R., White, J. L., Patel, E. U., Goel, R., Bloch, E. M., & Tobian, A. A. R. (2022) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2022.11.001 · Cited by 6 · see citing works
Preemptive intravenous iron therapy versus autologous whole blood therapy for early postoperative hemoglobin level in patients undergoing bimaxillary orthognathic surgery: a prospective randomized noninferiority trial
Chae, M. S., Lee, M., Choi, M. H., Park, J. U., Park, M., Kim, Y. H., Choi, H., Joo, J. D., & Moon, Y. E. (2021) · BMC Oral Health · doi:10.1186/s12903-020-01359-1 · Cited by 6 · see citing works
Visits to general practitioners after iron‐related deferrals from blood donation in middle‐aged and older Australian blood donors
Karki, S., Davison, T. E., Liu, B. C., Bell, K., Olynyk, J. K., Hayen, A. D., & Irving, D. O. (2021) · Transfusion · doi:10.1111/trf.16701 · Cited by 6 · see citing works
Iron deficiency among Japanese whole‐blood donors measured by serum ferritin
Odajima, T., Tsuno, N. H., Ishimaru, F., Okubo, R., Murakami, J., Kitsukawa, K., Ikuta, K., Matsuzaki, K., Muroi, K., Satake, M., et al. (2024) · Vox Sanguinis · doi:10.1111/vox.13688 · Cited by 6 · see citing works
Donor protection: Iron supplementation for frequent blood donors in Korea
Lee, S. J., Min, H., Jang, J. S., Lee, S., Chung, Y., & Kim, M. J. (2019) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2019.07.005 · Cited by 6 · see citing works
Deferral due to low hemoglobin and predictors of permanence in the blood donation system of repeat female blood donors
Urbina, A., García‐Otálora, M., Romero, D. M., Rocha, F., Rodríguez, Á. D. L. H., Palomino, F., & Weinauer, F. (2021) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2021.103340 · Cited by 6 · see citing works
Hepcidin as a diagnostic marker of iron deficiency in blood donors
Kaur, P., Kaur, G., Kaur, P., & Tahlan, A. (2021) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2021.103121 · Cited by 5 · see citing works
A computational model for prediction of ferritin and haemoglobin levels in blood donors
Paalvast, Y., Moazzen, S., Sweegers, M. G., Hogema, B. M., Janssen, M. P., & van den Hurk, K. (2022) · British Journal of Haematology · doi:10.1111/bjh.18367 · Cited by 5 · see citing works
Blood donors, iron deficiency and supplementation options – Will clinical trials help moving forward?
Garraud, O., Politis, C., & Vuk, T. (2022) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2022.103530 · Cited by 5 · see citing works
Examination of the relationship between iron status and cognitive function among healthy young women with and without a recent history of blood donation
France, J. L., Hod, E. A., Caccappolo, E., Suhr, J. A., France, C. R., Kessler, D. A., & Shaz, B. H. (2020) · Transfusion · doi:10.1111/trf.16069 · Cited by 5 · see citing works
Iron Supplementation and Blood Donation in Nigeria
Nwagha, T. U., Ugwu, A. O., & Nwaekpe, C. N. (2023) · Annals of African Medicine · doi:10.4103/aam.aam_248_21 · Cited by 4 · see citing works
Are we donating iron? Impact of apheresis on ferritin
Infanti, L. (2023) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2023.103668 · Cited by 3 · see citing works
Donor iron depletion in context
Vassallo, R. R. (2020) · Transfusion · doi:10.1111/trf.16219 · Cited by 3 · see citing works
Self-citation
Low ferritin levels appear to be associated with worsened health in male repeat blood donors
Palokangas, E., Lobier, M., Partanen, J., Castrén, J., & Arvas, M. (2021) · Vox Sanguinis · doi:10.1111/vox.13104 · Cited by 3 · see citing works
Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietin.Preprint
Karpova, D., Encabo, H., Donato, E., Kotova, I., Calderazzo, S., Leppae, A., Panten, J., Przybylla, A., Seifried, E., Kopp-Schneider, A., et al. (2022) · medRxiv · doi:10.1101/2022.07.24.22277825 · Cited by 2 · see citing works
Protection of fundamental human rights by improving patient access to plasma‐derived therapies and donor health protection
Thibert, J., von Bonsdorff, L., Plançon, J., de Angelis, V., So‐Osman, C., Erikstrup, C., Tiberghien, P., & van den Hurk, K. (2026) · Vox Sanguinis · doi:10.1111/vox.70245 · Cited by 2 · see citing works
Seasonal Variation of Ferritin among Swedish Blood Donors
Saldeen, J., Carlsson, L. M. S., & Larsson, A. O. (2022) · Laboratory Medicine · doi:10.1093/labmed/lmac053 · Cited by 2 · see citing works
The importance of plasma ferritin values in blood donors for the evaluation of body iron store in a five-month period
Ćatović-Baralija, E., Ahmetović-Karić, G., Hasić, S., Avdagić, N., & Babić, N. (2020) · Medicinski Glasnik · doi:10.17392/1223-21 · Cited by 2 · see citing works
Investigation on the feasibility of large‐volume autologous red blood cells donation: A pilot trial in a small cohort of Chinese
Wu, J., Chen, G., Wang, L., Wang, P., Han, Y., Yang, L., & Ouyang, X. (2023) · Journal of Clinical Apheresis · doi:10.1002/jca.22048 · Cited by 2 · see citing works
Effects of Iron Dietary Supplements to Prevent Iron Deficiency in Repeat Blood Donors
Lee, J. Y., Lee, J. S., Ko, D. Y., Seon, J. Y., Yang, J. H., Kim, J. N., & Youn, M. A. (2021) · The Korean Journal of Blood Transfusion · doi:10.17945/kjbt.2021.32.2.102 · Cited by 1 · see citing works
Exploring the association between blood donation and anemia: A cross‑sectional study based on the NHANES
Lv, C., Zeng, L., Zhu, W., & Wu, Z. (2025) · Transfusion Clinique et Biologique · doi:10.1016/j.tracli.2025.11.004 · Cited by 1 · see citing works
To Assess the Iron Reserves in Blood Donors by Measuring Serum Ferritin and Hemoglobin in the Children Hospital Lahore
Fateen, T., Ali, S. S., Saqlain, N., Shafqat, F., Khalid, A., Ali, K. S., & Kashif, Z. (2022) · Pakistan Journal of Medical and Health Sciences · doi:10.53350/pjmhs221610265 · Cited by 1 · see citing works
Experience with the prolonged release of iron in iron deficiency patients
Drozdov, V. N., Ших, Е. В., Astapovskii, A. A., & Николаевич, Ц. Д. (2023) · Meditsinskiy sovet = Medical Council · doi:10.21518/ms2023-105 · Cited by 1 · see citing works
Dietary intervention program based on short messages service for mothers of children with iron deficiency anemia
Ismail, M. S. M., Almakarem, A. S. A., Abdalla, S. S., Salem, N. M., Abdelwahed, A. Y., & Elbilgahy, A. A. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns9.14569 · Cited by 1 · see citing works
Association Between Race and Blood Ferritin Level of Whole Blood Donors
Akgun, Y. (2025) · Cureus · doi:10.7759/cureus.82926 · Cited by 1 · see citing works
A pilot study to assess Vitamin D and serum ferritin levels among prospective female blood donors with low hemoglobin levels
Mani, A., Nair, A. R., & Gupta, D. (2022) · Asian Journal of Transfusion Science · doi:10.4103/ajts.ajts_13_22 · Cited by 1 · see citing works
La Donación de Sangre
Ariño, L. S. A., & Sánchez, L. M. M. (2021) · Revista Repertorio de Medicina y Cirugía · doi:10.31260/repertmedcir.01217372.1036 · Cited by 1 · see citing works
Donor education – times change and we with time
O’Brien, S. F. (2020) · Transfusion · doi:10.1111/trf.15977 · Cited by 1 · see citing works
To Fe, or not to Fe, that is the question
Belizaire, R., & Stowell, S. R. (2022) · Blood · doi:10.1182/blood.2022017881 · Cited by 1 · see citing works
Sideropenia em doadores de sangue na unidade da Fundação Hemominas de Poços de Caldas
Spina, C. A. D. S. (2020) · doi:10.11606/d.17.2020.tde-11022020-165258
New Possibilities of Correction of Iron Deficiency Conditions in the Practice of a Family Doctor
Матюха, Л. Ф. (2020) · Family Medicine · doi:10.30841/2307-5112.1-2.2020.204547
Diffuse Hair Loss and Thinning: a Modern Perspective on the Problem and Approaches to Therapy
Проценко, Т. В. (2020) · Family Medicine · doi:10.30841/2307-5112.3.2020.211558
Blood Donor Medical Assessment, Collection, and Complications
Bachowski, G. J. (2021) · Transfusion Medicine · doi:10.1002/9781119599586.ch4
Epidemiology of blood donor health in the context of increased frequency of donation: The INTERVAL trial
Browne, A. (2020) · Apollo (University of Cambridge) · doi:10.17863/cam.75098
Hematology and Iron Status Evaluation Based on Donation Characteristics in Dr. Sardjito Hospital, Yogyakarta
Anshori, F., Ratnaningsih, T., & Triyono, T. (2021) · INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY · doi:10.24293/ijcpml.v27i3.1876
Identification and analysis of genetic and chemical modulators of iron metabolism
Hawula, Z. J. (2021) · Queensland University of Technology · doi:10.5204/thesis.eprints.225904
Time to eat : The diet of night shift workers from different dietary perspectives and its association with health and safety
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Authors: Kiss, J. E., & Vassallo, R. R.
Affiliations: Institute for Transfusion Medicine (US)
Chief Medical and Scientific Officer Blood Systems, Inc. Scottsdale AZ USA
Corresponding author: Kiss, Joseph E.
ORCID: Kiss, Joseph E.
Vassallo, Ralph R.
Venue: British Journal of Haematology
Publisher: Wiley
Published: 2018-05-16
Volume: 181
Issue: 5
Pages: 590-603
ISSN: 0007-1048 (ISSN-L)
1365-2141
DOI: 10.1111/bjh.15136
OpenAlex: W2803683681
Cited by: 92
References: 95
Citations by year: 2026: 6 · 2025: 8 · 2024: 6 · 2023: 13 · 2022: 13 · 2021: 20 · 2020: 14 · 2019: 10 · 2018: 2
FWCI: 1.90
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: British Journal of Haematology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
Social Sciences › Business, Management and Accounting › Management of Technology and Innovation › Blood donation and transfusion practices
Health Sciences › Medicine › Biochemistry › Blood transfusion and management
Keywords: iron deficiency, blood donors, repeat blood donation, iron supplementation, anemia, iron balance, fatigue, neuromuscular symptoms
MeSH terms: Iron Deficiencies, Blood Donors, Female, Humans, Iron, Male

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