Cited by 230Autism Spectrum Disorder ResearchBehavioral and Psychological StudiesChild Nutrition and Feeding Issues

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index; 1 of the 40 sources its claims cite were checked for support.

Clinical outcomes of an early intervention program for preschool children with Autism Spectrum Disorder in a community group setting.

Open access
Eapen, Valsamma, Črnčec, Rudi, Walter, Amelia·2013·BMC Pediatrics

Abstract

BACKGROUND: Available evidence indicates that early intervention programs, such as the Early Start Denver Model (ESDM), can positively affect key outcomes for children with Autism Spectrum Disorder (ASD). However, programs involving resource intensive one-to-one clinical intervention are not readily available or deliverable in the community, resulting in many children with ASD missing out on evidence-based intervention during their early and most critical preschool years. This study evaluated the effectiveness of the ESDM for preschool-aged children with ASD using a predominantly group-based intervention in a community child care setting. METHODS: Participants were 26 children (21 male) with ASD with a mean age of 49.6 months. The ESDM, a comprehensive early intervention program that integrates applied behaviour analysis with developmental and relationship-based approaches, was delivered by trained therapists during the child's attendance at a child care centre for preschool-aged children with ASD. Children received 15-20 hours of group-based, and one hour of one-to-one, ESDM intervention per week. The average intervention period was ten months. Outcome measures were administered pre- and post-intervention, and comprised a developmental assessment - the Mullen Scales of Early Learning (MSEL); and two parent-report questionnaires - the Social Communication Questionnaire (SCQ) and Vineland Adaptive Behaviours Scales-Second Edition (VABS-II). RESULTS: Statistically significant post-intervention improvements were found in children's performance on the visual reception, receptive language and expressive language domains of the MSEL in addition to their overall intellectual functioning, as assessed by standardised developmental quotients. Parents reported significant increases in their child's receptive communication and motor skills on the VABS-II, and a significant decrease in autism-specific features on the SCQ. These effects were of around medium size, and appeared to be in excess of what may have been expected due to maturation. Nonetheless, these results need to be confirmed in a controlled study. CONCLUSIONS: This study suggests community dissemination of the ESDM using predominantly group-based intervention may be an effective intervention. Making the ESDM accessible to the wider ASD community in child care settings has the potential for significant clinical and economic benefits. Further studies are indicated in this area, including those with younger children, and which incorporate a control group and standardised ASD assessments. TRIAL REGISTRATION: This trial is registered with the Australian New Zealand Clinical Trials Registry: Registry number ACTRN12612000461897.

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

In a pre-post community study, 26 preschool-aged children with ASD received the Early Start Denver Model (ESDM) mainly in a group child-care setting and showed significant improvements in several developmental, adaptive, and autism-symptom measures. The authors conclude this delivery model may be effective and feasible, but call for controlled confirmation.

Key findings

  • Significant post-intervention gains were found on the MSEL for overall developmental quotient (36.8 to 46.7, p<0.001, d=0.47), Visual Reception (35.9 to 51.5, p=0.001, d=0.63), Receptive Language (27.6 to 38.7, p<0.001, d=0.48), and Expressive Language (32.6 to 40.7, p=0.001, d=0.40); Fine Motor DQ did not improve significantly (47.9 to 51.3, p=0.28, d=0.14).
  • On the VABS-II, significant increases were reported for Receptive Communication (7.6 to 9.3, p=0.005, d=0.49), Gross Motor (9.3 to 11.7, p<0.001, d=0.87), and the Motor Skills domain standard score (66.4 to 73.7, p=0.02, d=0.45).
  • SCQ total scores decreased significantly from 18.5 to 15.7 (p=0.04, d=−0.39), and the percentage of children scoring below the clinical cut-off of 15 or more doubled from 21% at Time 1 to 42% at Time 2; parent-reported use of full sentences increased from 52% to 68%.
  • The authors note effect sizes were generally lower than those in Dawson et al.’s one-to-one ESDM trial, e.g., overall MSEL d=0.47 versus 0.87 in Dawson et al.

Methods

  • Pre-post study of 26 children (21 male) with DSM-IV-TR Autistic Disorder, mean age 49.6 months (SD 6.08, range 36–58 months), attending an Autism Specific Early Learning and Care Centre in metropolitan Sydney, Australia.
  • ESDM was delivered by trained therapists during child-care attendance: 15–20 hours per week of group intervention plus 1 hour per week of one-to-one intervention; average time between initial and follow-up assessment was 9.72 months (SD 2.91).
  • Outcomes were measured pre- and post-intervention with the MSEL, SCQ, and VABS-II; paired samples t-tests compared scores, with Cohen’s d effect sizes reported.

Limitations

  • Stated by the paper: lack of a control group; lack of a standardised observational measure of ASD diagnosis and severity; need for further studies with younger children and follow-up to assess durability.
  • Evident from the text: the pre-post design cannot establish that observed improvements were caused by ESDM rather than maturation or other factors; the sample was small (n=26), and there were missing data because some families did not complete measures within required timeframes.

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Integrity signals

Registry

Crossref · 10.1186/1471-2431-13-3

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Figures

Figure 1 Approximate developmental trajectory of study participants before and during group ESDM intervention, compared to a typical developmental trajectory. a. MSEL scores were calculated by taking the average of the age equivalent scores obtained in the four completed MSEL subscales (i.e., Visual Reception, Fine Motor, Receptive Language and Expressive Language) in order to provide an estimate of overall intellectual ability.
Figure 1 Approximate developmental trajectory of study participants before and during group ESDM intervention, compared to a typical developmental trajectory. a. MSEL scores were calculated by taking the average of the age equivalent scores obtained in the four completed MSEL subscales (i.e., Visual Reception, Fine Motor, Receptive Language and Expressive Language) in order to provide an estimate of overall intellectual ability.CC BY · PubMed Central

Verification

Claims the paper makes

30 Not checked yet · 17 Own result · 10 Own interpretation · 9 Own method · 1 Partly supported · accuracy not yet measured

Verify all 39 references — free account

Show all 44 claims

  • It may state two separate claims as one. 10
  • Probably not a substantial claim. 15
23 of 23
  • The paper relies on this without support.

    The observed pre-post improvements are attributable to the ESDM intervention rather than to maturation or other concurrent factors.

    “This study suggests community dissemination of the ESDM using predominantly group-based intervention may be an effective intervention.”
  • The paper relies on this without support.

    The sample of 26 preschool children with ASD attending an ASELCC is representative of the wider population of preschool children with ASD in community settings.

    “This study suggests community dissemination of the ESDM using predominantly group-based intervention may be an effective intervention.”
  • The paper relies on this without support.

    No other interventions or therapies were received by the children during the study period.

    “None of the participants were receiving an EIBI outside of the ESDM intervention offered as part of the study.”
  • The paper relies on this without support.

    The missing data did not bias the results.

    “No families withdrew from the study during the course of the intervention; however, there were some instances of missing data due to families not completing measures within the necessary timeframes.”
  • The paper relies on this without support.

    The ESDM curriculum can be delivered in a group setting without losing its efficacy.

    “Other than accommodations to allow translation to the group context, no modifications were made to the ESDM curriculum.”
  • The paper relies on this without support.

    The SCQ and VABS-II have acceptable test-retest reliability.

    “The SCQ and VABS-II have acceptable test-retest reliability, suggesting that measurement errors were not a key factor.”
  • The paper relies on this without support.

    The ESDM is designed to enhance the social attention and communicative abilities of young children with ASD, with particular focus on social attention, affect sharing, imitation and joint attention.

    “Given that the ESDM is designed to enhance the social attention and communicative abilities of young children with an ASD, with particular focus on the critical skills of social attention, affect sharing, imitation and joint attention, the significant gains made in the respective domains of visual reception and receptive and expressive communication are noteworthy.”
  • The paper relies on this without support.

    One-to-one intervention starting at the youngest possible age offers the best opportunity for improving outcomes in children with ASD.

    “this is in keeping with the existing evidence that one-to-one intervention starting at the youngest possible age offers the best opportunity for improving outcomes in children with ASD.”
  • The paper relies on this without support.

    Intervention programs provided within day care and preschool settings offer greater opportunities for generalisation of skills and improvements to school readiness, resulting in easier transition to other education settings following intervention.

    “Intervention programs provided within day care and preschool settings offer greater opportunities for generalisation of skills and improvements to school readiness, resulting in easier transition to other education settings following intervention.”
9 of 9

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Citations

Cites

Show all 37 references

Research works printed but not linked: 2

  1. Rutter M, Bailey A, Lord C: Social communication questionnaire (SCQ). 2003, Los Angeles, CA: Western Psychological Services
  2. Sparrow S, Cicchetti D, Balla D: Vineland adaptive behavior scales: (Vineland II), survey interview form/caregiver rating form. 2005, Livonia, MN: Pearson Assessments

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Metadata

Authors
Eapen, V., Črnčec, R., & Walter, A.
Affiliations
  • South Western Sydney Local Health District (AU)
  • UNSW Sydney (AU)
Corresponding author
Eapen, Valsamma
Venue
BMC Pediatrics
Published
2013-01-07
Volume
13
Issue
1
Pages
3-3
ISSN
1471-2431 (ISSN-L)
OpenAlex
W2123545643
Cited by
230
References
37
Citations by year
2026: 10 · 2025: 13 · 2024: 16 · 2023: 18 · 2022: 63 · 2021: 11 · 2020: 13 · 2019: 18 · 2018: 15 · 2017: 12 · 2016: 10 · 2015: 14 · 2014: 10 · 2013: 6
FWCI
7.18
Type
journal article
Language
en
Open access
Locations
  • BMC Pediatrics (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • UNSWorks (University of New South Wales, Sydney, Australia) (submittedVersion, cc-by-nc-nd)
Funders
  • Australian Government
  • University of New South Wales
  • University of California, Davis
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Keywords
autism spectrum disorder, Early Start Denver Model, early intervention, preschool children, group intervention, community-based childcare, community dissemination, applied behaviour analysis, language development, adaptive behavior, parent-reported outcomes, Mullen Scales of Early Learning
MeSH terms
Behavior Therapy, Child, Child Development Disorders, Pervasive, Child, Preschool, Female, Humans, Male, New South Wales, Treatment Outcome, Early Intervention, Educational

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