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Cited by 268

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Dietary biomarkers: advances, limitations and future directions

Open access
Hedrick, Valisa E, Dietrich, Andrea M, Estabrooks, Paul A, Savla, Jyoti, Serrano, Elena, Davy, Brenda M·2012·Nutrition Journal

Abstract

The subjective nature of self-reported dietary intake assessment methods presents numerous challenges to obtaining accurate dietary intake and nutritional status. This limitation can be overcome by the use of dietary biomarkers, which are able to objectively assess dietary consumption (or exposure) without the bias of self-reported dietary intake errors. The need for dietary biomarkers was addressed by the Institute of Medicine, who recognized the lack of nutritional biomarkers as a knowledge gap requiring future research. The purpose of this article is to review existing literature on currently available dietary biomarkers, including novel biomarkers of specific foods and dietary components, and assess the validity, reliability and sensitivity of the markers. This review revealed several biomarkers in need of additional validation research; research is also needed to produce sensitive, specific, cost-effective and noninvasive dietary biomarkers. The emerging field of metabolomics may help to advance the development of food/nutrient biomarkers, yet advances in food metabolome databases are needed. The availability of biomarkers that estimate intake of specific foods and dietary components could greatly enhance nutritional research targeting compliance to national recommendations as well as direct associations with disease outcomes. More research is necessary to refine existing biomarkers by accounting for confounding factors, to establish new indicators of specific food intake, and to develop techniques that are cost-effective, noninvasive, rapid and accurate measures of nutritional status.

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Metadata

Authors
Hedrick, V. E., Dietrich, A. M., Estabrooks, P. A., Savla, J., Serrano, E., & Davy, B. M.
Venue
Nutrition Journal
Published
2012-12
Volume
11
Issue
1
Pages
109-109
ISSN
1475-2891 (ISSN-L)
OpenAlex
W2104893499
Cited by
268
References
11
FWCI
14.18
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Dietary biomarkers: advances, limitations and future directions. https://app.cochat.ai/papers/10.1186/1475-2891-11-109
The paper
Hedrick, V. E., Dietrich, A. M., Estabrooks, P. A., Savla, J., Serrano, E., & Davy, B. M. (2012). Dietary biomarkers: advances, limitations and future directions. Nutrition Journal. https://doi.org/10.1186/1475-2891-11-109

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.