Effect of dietary resveratrol on the metabolic profile of nutrients in obese OLETF rats

Prevalence and trends in obesity among US adults, 1999–2000

Flegal, K. M. (2002) · JAMA · doi:10.1001/jama.288.14.1723 · Cited by 6,190 · see citing works

The Disease Burden Associated With Overweight and Obesity

Must, A. (1999) · JAMA · doi:10.1001/jama.282.16.1523 · Cited by 4,804 · see citing works

Regional adiposity and morbidity.

Kissebah, A. H., & Krakower, G. R. (1994) · Physiological Reviews · doi:10.1152/physrev.1994.74.4.761 · Cited by 1,132 · see citing works

Determination of glycogen in small tissue samples.

Lo, S., Russell, J., & Taylor, A. (1970) · Journal of applied physiology · doi:10.1152/jappl.1970.28.2.234 · Cited by 884 · see citing works

The Medical Risks of Obesity

Pi-Sunyer, X. (2002) · Obesity Surgery · doi:10.1007/bf03342140 · Cited by 828 · see citing works

Polyphenols and prevention of cardiovascular diseases

Manach, C., Mazur, A., & Scalbert, A. (2005) · Current Opinion in Lipidology · doi:10.1097/00041433-200502000-00013 · Cited by 680 · see citing works

Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

Viollet, B., Foretz, M., Guigas, B., Horman, S., Dentin, R., Bertrand, L., Hue, L., & Andréelli, F. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.108506 · Cited by 529 · see citing works

Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice

Kim, S., Jin, Y., Choi, Y., & Park, T. (2011) · Biochemical Pharmacology · doi:10.1016/j.bcp.2011.03.012 · Cited by 332 · see citing works

Medium-chain fatty acids: Functional lipids for the prevention and treatment of the metabolic syndrome

Nagao, K., & Yanagita, T. (2009) · Pharmacological Research · doi:10.1016/j.phrs.2009.11.007 · Cited by 282 · see citing works

Bioactive lipids in metabolic syndrome

Nagao, K., & Yanagita, T. (2008) · Progress in Lipid Research · doi:10.1016/j.plipres.2007.12.002 · Cited by 187 · see citing works

Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress

Gómez‐Zorita, S., Fernández‐Quintela, A., Macarulla, M. T., Aguirre, L., Hijona, E., Bujanda, L., Milagro, F. I., Martínez, J. A., & Portillo, M. P. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511002753 · Cited by 164 · see citing works

Resveratrol ameliorates diabetes‐related metabolic changes via activation of AMP‐activated protein kinase and its downstream targets in db/db mice

Do, G., Jung, U. J., Park, H., Kwon, E., Jeon, S.-M., McGregor, R. A., & Choi, M. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200067 · Cited by 141 · see citing works

Effect of Dietary Omega 3 Phosphatidylcholine on Obesity-Related Disorders in Obese Otsuka Long-Evans Tokushima Fatty Rats

Shirouchi, B., Nagao, K., Inoue, N., Ohkubo, T., Hibino, H., & Yanagita, T. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf071225x · Cited by 130 · see citing works

Fat adaptation in well-trained athletes: effects on cell metabolism

Yeo, W. K., Carey, A. L., Burke, L., Spriet, L. L., & Hawley, J. A. (2011) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h10-089 · Cited by 118 · see citing works

Changes in white adipose tissue metabolism induced by resveratrol in rats

Alberdi, G., Rodríguez, V. M., Miranda, J., Macarulla, M. T., Arias, N., Andrés‐Lacueva, C., & Portillo, M. P. (2011) · Nutrition & Metabolism · doi:10.1186/1743-7075-8-29 · Cited by 118 · see citing works

Dietary effect of pomegranate seed oil rich in 9cis, 11trans, 13cis conjugated linolenic acid on lipid metabolism in obese, hyperlipidemic OLETF Rats

Arao, K., Wang, Y., Inoue, N., Hirata, J., Jae-Young, C. H. A., Nagao, K., & Yanagita, T. (2004) · Lipids in Health and Disease · doi:10.1186/1476-511x-3-24 · Cited by 113 · see citing works

The 10trans,12cis isomer of conjugated linoleic acid suppresses the development of hypertension in Otsuka Long–Evans Tokushima fatty rats

Nagao, K., Inoue, N., Wang, Y., Hirata, J., Shimada, Y., Nagao, T., Matsui, T., & Yanagita, T. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00929-x · Cited by 91 · see citing works

The 10trans, 12cis isomer of conjugated linoleic acid promotes energy metabolism in OLETF rats.

Nagao, K., Wang, Y.-M., Inoue, N., Han, S.-Y., Buang, Y., Noda, T., Kouda, N., Okamatsu, H., & Yanagita, T. (2003) · Nutrition (Burbank, Los Angeles County, Calif.) · doi:10.1016/s0899-9007(03)00060-1 · Cited by 91 · see citing works

Fat adaptation followed by carbohydrate restoration increases ampk activity in skeletal muscle from trained humans

Yeo, W. K., Lessard, S. J., Chen, Z.-P., Garnham, A. P., Burke, L. M., Rivas, D. A., Kemp, B. E., & Hawley, J. A. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90540.2008 · Cited by 73 · see citing works

Screening of soy protein-derived hypotriglyceridemic di-peptides in vitro and in vivo

Inoue, N., Nagao, K., Sakata, K., Yamano, N., Gunawardena, P. E. R., Han, S.-Y., Matsui, T., Nakamori, T., Furuta, H., Takamatsu, K., et al. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-85 · Cited by 72 · see citing works

Dietary Phosphatidylinositol Prevents the Development of Nonalcoholic Fatty Liver Disease in Zucker (fa/fa) Rats

Shirouchi, B., Nagao, K., Inoue, N., Furuya, K., Koga, S., Matsumoto, H., & Yanagita, T. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf703578d · Cited by 64 · see citing works

Resveratrol inhibits MMP-9 expression by up-regulating PPAR α expression in an oxygen glucose deprivation-exposed neuron model

Cheng, G., Zhang, X., Gao, D., Jiang, X., & Dong, W. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.12.045 · Cited by 59 · see citing works

Polyphenolic extract of lotus root (edible rhizome of Nelumbo nucifera) alleviates hepatic steatosis in obese diabetic db/db mice

Tsuruta, Y., Nagao, K., Kai, S., Tsuge, K., Yoshimura, T., Koganemaru, K., & Yanagita, T. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-202 · Cited by 56 · see citing works

Campest-5-en-3-one, an oxidized derivative of campesterol, activates PPARα, promotes energy consumption and reduces visceral fat deposition in rats

Ikeda, I., KONNO, R., Shimizu, T., Ide, T., Takahashi, N., Kawada, T., Nagao, K., Inoue, N., Yanagita, T., & Hamada, T. (2006) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2006.02.017 · Cited by 52 · see citing works

Repeated and long-term treatment with physiological concentrations of resveratrol promotes NO production in vascular endothelial cells

Takahashi, S., & Nakashima, Y. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511003588 · Cited by 46 · see citing works

Resveratrol and Its Analogues: Promising Antitumor Agents

Zhu, H. (2011) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152011795677427 · Cited by 46 · see citing works

Effects of Citrus Auraptene (7-Geranyloxycoumarin) on Hepatic Lipid Metabolism in Vitro and in Vivo

Nagao, K., Yamano, N., Shirouchi, B., Inoue, N., Murakami, S., Sasaki, T., & Yanagita, T. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf1020329 · Cited by 40 · see citing works

Isomer-Specific Anti-Obese and Hypolipidemic Properties of Conjugated Linoleic Acid in Obese OLETF Rats

Wang, Y., Nagao, K., Inoue, N., Ujino, Y., Shimada, Y., Nagao, T., Iwata, T., Kamegai, T., Yamauchi‐Sato, Y., & Yanagita, T. (2006) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70.355 · Cited by 38 · see citing works

The Medical Risks of Obesity

Pi‐Sunyer, F. X. (2002) · Obesity Surgery · doi:10.1381/096089202762552601 · Cited by 38 · see citing works

Obesity and target organ damage: diabetes

Adler, A. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0802212 · Cited by 35 · see citing works

Mukitake mushroom (Panellus serotinus) alleviates nonalcoholic fatty liver disease through the suppression of monocyte chemoattractant protein 1 production in db/db mice

Nagao, K., Inoue, N., Inafuku, M., Shirouchi, B., Morooka, T., Nomura, S., Nagamori, N., & Yanagita, T. (2009) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2009.01.021 · Cited by 27 · see citing works

Effect ofVaccinium ashei readeLeaf Extracts on Lipid Metabolism in Obese OLETF Rats

Inoue, N., Nagao, K., Nomura, S., Shirouchi, B., Inafuku, M., Hirabaru, H., Nakahara, N., Nishizono, S., Tanaka, T., & Yanagita, T. (2011) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.110451 · Cited by 24 · see citing works

Protective effects of fractional extracts fromPanellus serotinuson non-alcoholic fatty liver disease in obese, diabeticdb/dbmice

Inafuku, M., Nagao, K., Nomura, S., Shirouchi, B., Inoue, N., Nagamori, N., Nakayama, H., Toda, T., & Yanagita, T. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511003485 · Cited by 16 · see citing works

Novel insights of dietary polyphenols and obesity

Wang, S. F., Moustaïd‐Moussa, N., Chen, L., Mo, H., Shastri, A. A., Su, R., Bapat, P., Kwun, I., & Shen, C. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.09.001 · Cited by 903 · see citing works

Resveratrol: Anti-Obesity Mechanisms of Action

Aguirre, L., Fernández-Quintela, A., Arias, N., & Portillo, M. (2014) · Molecules · doi:10.3390/molecules191118632 · Cited by 205 · see citing works

Functional foods as potential therapeutic options for metabolic syndrome

Brown, L., Poudyal, H., & Panchal, S. K. (2015) · Obesity Reviews · doi:10.1111/obr.12313 · Cited by 159 · see citing works

Comparative Studies on Polyphenolic Composition, Antioxidant and Diuretic Effects of Nigella sativa L. (Black Cumin) and Nigella damascena L. (Lady-in-a-Mist) Seeds

Toma, C.-C., Oláh, N.-K., Vlase, L., Mogoșan, C., & Mocan, A. (2015) · Molecules · doi:10.3390/molecules20069560 · Cited by 119 · see citing works

Medicinal Chemistry of the Epigenetic Diet and Caloric Restriction

Martin, S., Hardy, T. M., & Tollefsbol, T. (2013) · Current Medicinal Chemistry · doi:10.2174/09298673113209990189 · Cited by 78 · see citing works

The Role of Resveratrol Administration in Human Obesity

Mongioì, L. M., La Vignera, S., Cannarella, R., Cimino, L., Compagnone, M., Condorelli, R. A., & Calogero, A. E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094362 · Cited by 71 · see citing works

Deciphering the Anti-obesity Benefits of Resveratrol: The “Gut Microbiota-Adipose Tissue” Axis

Zhou, L., Xiao, X., Zhang, Q., Zheng, J., & Deng, M. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00413 · Cited by 66 · see citing works

Doses of Quercetin in the Range of Serum Concentrations Exert Delipidating Effects in 3T3-L1 Preadipocytes by Acting on Different Stages of Adipogenesis, but Not in Mature Adipocytes

Eseberri, I., Miranda, J., Lasa, A., Churruca, I., & Portillo, M. P. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/480943 · Cited by 61 · see citing works

ProbioticLactobacillus gasseriSBT2055 improves glucose tolerance and reduces body weight gain in rats by stimulating energy expenditure

Shirouchi, B., Nagao, K., Umegatani, M., Shiraishi, A., Morita, Y., Kai, S., Yanagita, T., Ogawa, A., Kadooka, Y., & Satô, M. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516002245 · Cited by 61 · see citing works

Pterostilbene, a dimethylated analog of resveratrol, promotes energy metabolism in obese rats

Nagao, K., Jinnouchi, T., Kai, S., & Yanagita, T. (2017) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2017.02.009 · Cited by 57 · see citing works

Antiobesity effects of resveratrol: which tissues are involved?

Fernández‐Quintela, A., Milton‐Laskibar, I., González, M. A., & Portillo, M. P. (2017) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13413 · Cited by 51 · see citing works

Soy β-conglycinin improves obesity-induced metabolic abnormalities in a rat model of nonalcoholic fatty liver disease

Wanezaki, S., Tachibana, N., Nagata, M., Saito, S., Nagao, K., Yanagita, T., & Kohno, M. (2014) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2014.03.005 · Cited by 46 · see citing works

Hepatoprotective and Antioxidant Potential of Organic and Conventional Grape Juices in Rats Fed a High-Fat Diet

Buchner, I., Medeiros, N. D. S., Lacerda, D. D. S., Normann, C. A. B. M., Gemelli, T., Rigon, P., Wannmacher, C. M. D., Henriques, J. A. P., Dani, C., & Funchal, C. (2014) · Antioxidants · doi:10.3390/antiox3020323 · Cited by 45 · see citing works

Polyphenols and obesity prevention: critical insights on molecular regulation, bioavailability and dose in preclinical and clinical settings

Santis, S. D., Clodoveo, M. L., Cariello, M., D’Amato, G., Franchini, C., Faienza, M. F., & Corbo, F. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1765736 · Cited by 42 · see citing works

Anti-obesity effects of resveratrol: comparison between animal models and humans

Fernández‐Quintela, A., Carpéné, C., Fernández, M., Aguirre, L., Milton‐Laskibar, I., Contreras, J., & Portillo, M. P. (2016) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-016-0544-y · Cited by 41 · see citing works

Phytotherapy and the Role of Bioactive Compounds in Modulating Mechanisms of Overweight and Obesity Comorbid with Depressive Symptoms—A Scoping Review of Mechanisms of Action

Sochacka, K., & Lachowicz, S. (2025) · Molecules · doi:10.3390/molecules30132827 · Cited by 16 · see citing works

Dietary Sparassis crispa Reduces Body Fat Mass and Hepatic Lipid Levels by Enhancing Energy Expenditure and Suppressing Lipogenesis in Rats

Takeyama, A., Nagata, Y., Shirouchi, B., Nonaka, C., Aoki, H., Haraguchi, T., Sato, M., Tamaya, K., Yamamoto, H., & Tanaka, K. (2018) · Journal of Oleo Science · doi:10.5650/jos.ess18043 · Cited by 11 · see citing works

Resveratrol alleviates obesity‑associated podocyte injury in ovariectomized obese rats

Li, B., Xiao, X., Miao, Y., Guo, L. C., Zhen, J., Li, X., Jiang, B., & Hu, Z. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.8178 · Cited by 9 · see citing works

Modulation of adipocyte size and fat pad weight via resveratrol releasing scaffolds implanted into the epididymal adipose tissue

Murphy, K. P., Hendley, M. A., Patterson, A. T., Hall, H. E., Carter, G. J., Isely, C., & Gower, R. M. (2020) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37063 · Cited by 9 · see citing works

Herbal adaptogens combined with protein fractions from bovine colostrum and hen egg yolk reduce liver TNF-α expression and protein carbonylation in Western diet feeding in rats

Mobley, C. B., Toedebusch, R. G., Lockwood, C. M., Heese, A. J., Zhu, C., Krieger, A. C., Cruthirds, C. L., Hofheins, J. C., Wiedmeyer, C. E., Kim, D. Y., et al. (2014) · Nutrition & Metabolism · doi:10.1186/1743-7075-11-19 · Cited by 7 · see citing works

Biochemical effect of resveratrol on Lipids profile and hepatic oxidative stress in experimentally induced obesity in female rats

Hussein, S. A., Abdelmagid, A. D., & Fareed, F. (2017) · Benha Veterinary Medical Journal · doi:10.21608/bvmj.2017.31114 · Cited by 7 · see citing works

Dietary Cholest-4-en-3-one, a Cholesterol Metabolite of Gut Microbiota, Alleviates Hyperlipidemia, Hepatic Cholesterol Accumulation, and Hyperinsulinemia in Obese, Diabetic db/db Mice

Higuchi, M., Okumura, M., Mitsuta, S., & Shirouchi, B. (2024) · Metabolites · doi:10.3390/metabo14060321 · Cited by 6 · see citing works

Resveratrol as Anti-Obesity and Anticancer Agent

Gupta, V. K., Sonker, P., & Kumar, A. (2021) · Springer eBooks · doi:10.1007/978-981-16-1846-8_10 · Cited by 3 · see citing works

How Do Structurally Distinct Compounds Exert Functionally Identical Effects in Combating Obesity?

Deng, Z., Liu, R.-X., Li, A., Guo, J., & Zeng, Q.-P. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00069 · Cited by 3 · see citing works

Efficacy ofFicusspp. on renal injury induced by hypercholesterolaemia

Awad, N. E., Hamed, M. A. A., Seida, A. A., & Elbatanony, M. M. (2012) · Natural Product Research · doi:10.1080/14786419.2011.570760 · Cited by 3 · see citing works

Epigenetics of Human Obesity: A Link Between Genetics and Nutrition

Albuquerque, D., Manco, L., & Nóbrega, C. (2014) · Springer eBooks · doi:10.1007/978-3-319-12766-8_8 · Cited by 2 · see citing works

The effect of L-DOPA and natural products on age-related motor deficits and dopaminergic cell survival

Allen, E. N. (2013)

Decoding red wine’s effects: Cardiovascular and metabolic disorders in animal research

Bomfim, G. H. S., Musial, D. C., & Aguiar, T. F. M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-29192-0.00052-2

Comparative anti-obesity efficacy of high-interest natural products in preclinical models: a bibliometric and network meta-analysis

Chen, Y.-X., Yang, Q.-W., Zhang, L., Sun, M.-H., Tong, H.-Y., Yi-yu, D., Hu, Y., Jiang, L., Liu, J.-T., & Zhao, J. X. (2026) · Food & Function · doi:10.1039/d6fo03150a

Hepatic lipid metabolic pathways modified by resveratrol in rats fed an obesogenic diet

Alberdi, G., Rodríguez, V. M., Macarulla, M. T., Miranda, J., Churruca, I., & Portillo, M. P. (2012) · Nutrition · doi:10.1016/j.nut.2012.09.011 · Cited by 106 · see citing works

Biochemical effect of resveratrol on Lipids profile and hepatic oxidative stress in experimentally induced obesity in female rats

Hussein, S. A., Abdelmagid, A. D., & Fareed, F. (2017) · Benha Veterinary Medical Journal · doi:10.21608/bvmj.2017.31114 · Cited by 7 · see citing works

Resveratrol attenuates oxidative stress and prevents steatosis and hypertension in obese rats programmed by early weaning

Franco, J. G., Lisboa, P. C., Lima, N. S., Amaral, T. A. S., Peixoto‐Silva, N., Resende, Â. C., OLIVEIRA, E. B. D., Passos, M. C. F., & de Moura, E. G. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2012.06.019 · Cited by 89 · see citing works

Role of resveratrol metabolites in adipose function

Allan, M. L. (2014) · Purdue e-Pubs (Purdue University System)

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Timmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.10.002 · Cited by 1,320 · see citing works