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Cited by 30Muscle metabolism and nutritionSports Performance and TrainingMuscle activation and electromyography studies

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Effects of creatine loading on electromyographic fatigue threshold during cycle ergometry in college-aged women

Open access
Smith, Abbie E, Walter, Ashley A, Herda, Trent J, Ryan, Eric D, Moon, Jordan R, Cramer, Joel T, Stout, Jeffrey R·2007·Journal of the International Society of Sports Nutrition
DOI 10.1186/1550-2783-4-20PMC PMC2244642
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Abstract

The purpose of this study was to examine the effects of 5 days of Creatine (Cr) loading on the electromyographic fatigue threshold (EMGFT) in college-aged women. Fifteen healthy college-aged women (mean +/- SD = 22.3 +/- 1.7 yrs) volunteered to participate in this double-blind, placebo-controlled study and were randomly placed into either placebo (PL - 10 g of flavored dextrose powder; n = 8) or creatine (Cr - 5 g di-creatine citrate plus 10 g of flavored dextrose powder; n = 7; Creatine Edge, FSI Nutrition) loading groups. Each group ingested one packet 4 times per day (total of 20 g/day) for 5 days. Prior to and following supplementation, each subject performed a discontinuous incremental cycle ergometer test to determine their EMGFT value, using bipolar surface electrodes placed on the longitudinal axis of the right vastus lateralis. Subjects completed a total of four, 60 second work bouts (ranging from 100-350 W). The EMG amplitude was averaged over 10 second intervals and plotted over the 60 second work bout. The resulting slopes from each successive work bouts were used to calculate EMGFT. A two-way ANOVA (group [Cr vs. PL] x time [pre vs. post]) resulted in a significant (p = 0.031) interaction. Furthermore, a dependent samples t-test showed a 14.5% +/- 3.5% increase in EMGFT from pre- to post-supplementation with Cr (p = 0.009), but no change for the PL treatment (-2.2 +/- 5.8%; p = 0.732). In addition, a significant increase (1.0 +/- 0.34 kg; p = 0.049) in weight (kg) was observed in the Cr group but no change for PL (-0.2 kg +/- 0.2 kg). These findings suggest that 5 days of Cr loading in women may be an effective strategy for delaying the onset of neuromuscular fatigue during cycle ergometry.

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Crossref · 10.1186/1550-2783-4-20

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  • CC is able to delay the onset of neuromuscular fatigue during cycle ergometry.

    “High-dose, short-term CC supplementation (4 × 5 g CC per day for 5 days) has been found to increase anaerobic working capacity (AWC) in healthy physically active women (Eckerson et al. 2004) and is able to delay the onset of neuromuscular fatigue during cycle ergometry (Smith et al. 2007).”

    From Analysis of the efficacy, safety, and regulatory status of novel forms of creatine (2011) · cites this paper as Smith et al. 2007

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Citations

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Research works printed but not linked: 37

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Metadata

Authors
Smith, A. E., Walter, A. A., Herda, T. J., Ryan, E. D., Moon, J. R., Cramer, J. T., & Stout, J. R.
Affiliations
  • Metabolic and Body Composition Laboratory, Department of Health and Exercise ScienceUniversity of Oklahoma 73019 Norman OK USA
  • University of Oklahoma (US)
Corresponding author
Stout, Jeffrey R
ORCID
Venue
Journal of the International Society of Sports Nutrition
Publisher
Informa UK Limited
Published
2007-07-13
Volume
4
Issue
1
Pages
20-20
ISSN
1550-2783 (ISSN-L)
DOI
10.1186/1550-2783-4-20
PMC
PMC2244642
OpenAlex
W2159476091
Cited by
30
References
6
Citations by year
2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2019: 3 · 2017: 2 · 2016: 4 · 2015: 1 · 2014: 1 · 2013: 3 · 2012: 1
FWCI
0.26
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of the International Society of Sports Nutrition (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • KU ScholarWorks (University of Kansas) (submittedVersion, other-oa)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Physical Sciences › Engineering › Biomedical Engineering › Muscle activation and electromyography studies
Keywords
creatine supplementation, creatine loading, neuromuscular fatigue, cycle ergometry, women, vastus lateralis, dextrose placebo, weight gain

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